Haptens to antibody. Medical search. Frequent questions

And if the desired application is for consistent antibody results with easy large scale production, recombinant monoclonal antibodies may be suggested. (prosci-services.com)
Ion channel therapeutic monoclonal antibodies · 22. (synabs.be)
Although the idea of generating therapeutic monoclonal antibodies that block or agonize ion channels, which are membrane proteins, seems to be self-evident, its implementation is more complicated than expected. (synabs.be)
Consequently chimeric, humanised and human monoclonal antibodies have been created, produced and get used nowadays. (wikipedia.org)
Possible was this approach because of the development of monoclonal Antibodies which could be connected to radiometal chelates. (wikipedia.org)
Monoclonal antibodies (mAbs) directed against tumor-associated antigens have excellent characteristics to target tumor cells selectively ( 1 - 3 ). (snmjournals.org)
A total of seven rabbit polyclonal antibodies (pAbs) and 21 mouse monoclonal antibodies (mAbs) with various recognition properties were obtained. (bvsalud.org)

Interaction of smoking and atopy in producing specific IgE antibody against a hapten protein conjugate. (ox.ac.uk)
Using a radioallergosorbent test with a tetrachlorophthalic anhydride human serum albumin conjugate, specific IgE antibody was detected in serum from 24 out of 300 factory floor workers exposed to tetrachlorophthalic anhydride. (ox.ac.uk)
Smoking may predispose to, and interact with atopy in, the production of specific IgE antibody to this hapten protein conjugate. (ox.ac.uk)
These findings imply that carrier-specific helper T cells do not play a controlling role in determining whether high- or low-avidity hapten-specific B-cell precursors will proliferate in response to challenge with a hapten-carrier conjugate. (johnshopkins.edu)
Among them AAT Bioquest's Buccutite™ crosslinking technology offer the most efficient method to conjugate antibodies with macromolecules such as enzyme tags. (stratech.co.uk)
The formation of anti-DNP reaginic antibody was completely suppressed by treatment of mice with a conjugate consisting of the hapten coupled to an isologous, nonimmunogenic carrier, viz. (aai.org)
Hapten-heterologous carrier conjugates elicited antihapten titers similar in magnitude to those elicited by the homologous carrier conjugate. (caltech.edu)

We recommend analyzing the immunogenic variables of the small molecule hapten and application of interest since each application presents antigens in a distinct way. (prosci-services.com)
The first radiolabelled antibodies were used in the early 1950s and got used for cancer therapy, but it took roughly two more decades before it was demonstrated that they target human tumour associated antigens in cancer patients. (wikipedia.org)
Our biopharmaceutical company specializes in delivering precision-engineered products tailored for Carprofen research and applications, offering a comprehensive range that includes anti-small molecule antibodies and small molecule competitive antigens. (genemedi.net)
These encompass various forms, such as Carrier-coupled antigens, immunogens, hapten-carrier conjugates, BSA-conjugated, and OVA-conjugated variants, designed to cater to diverse scientific needs. (genemedi.net)
The specificity of tissue antigens has previously been investigated by the usual immunologic procedures [1] and the effects of antibodies [2,3] upon tissue explants has long been known. (caltech.edu)
The problem of obtaining from precipitation experiments evidence about the structure of antibodies and the nature of serological reactions is obviously greatly simplified by the replacement of protein antigens by simple substances of known structure. (caltech.edu)
A company seeks a process of making high-affinity antibodies (or other substances) that can bind rapidly to antigens of large molecular sizes, such as proteins. (farmavita.net)
The concept is also used for chemicals as antigens or haptens. (bvsalud.org)

A judicious alternative to chemical molecules and small peptides with short half-life is the monoclonal antibody where high levels of specificity would be expected to mitigate off-target effects, and generate safer and more potent classes of drugs. (synabs.be)
This can be provided by using a biomarker which has a high affinity and specificity for its target (e.g. an antibody). (wikipedia.org)
Owing to their high affinity and specificity, antibodies have been considered as suitable vehicles for imaging and therapeutics, since the beginning of the 20th Century. (wikipedia.org)
Pretargeting strategies can lead to an improved imaging contrast, as it combines the high target specificity and affinity of an antibody with the fast pharmacokinetic properties of a small molecule. (wikipedia.org)
In this approach a nonradiolabeled bispecific monoclonal antibody (bs-mAb) with antitumor-associated antigen (TAA) and antihapten specificity is injected in the first phase. (snmjournals.org)
The growth and function of tissue explants have previously been used to study the specificity of tissue antibodies [4,5], but the antisera used were of low, uncertain potency, and only a few different tissues were examined in testing the toxic effects. (caltech.edu)
Cross-reactivity with selected E(2)-related endogenous steroids strongly suggested that scFv#m2-c4 has improved specificity compared to conventional antibodies. (lu.se)

Selectivity of the assay was assessed by measuring cross-reactivity of antibody M6122 to related congeners such as aglycones and the 2'-glycosides of hesperetin dihydrochalcone, 5 and phloretin, 6. (cdc.gov)
Fluorophore-linked immunosorbent assay: FITC Antibody [NB100-64617] - FLISA plate was coated with Goat Anti-Human IgG-FITC and Goat Anti-Human IgG-BIOT. (novusbio.com)
Thus, genetically engineered antibodies, which have much higher affinities than native antibodies, should increase assay sensitivities. (lu.se)

Characterization of polyclonal antibodies to the Ah receptor prepared by immunization with a synthetic peptide hapten. (aspetjournals.org)
Rabbit polyclonal and single chain Fv (scFv) antibodies were produced to aflatoxin Bi. (dcu.ie)
Both the polyclonal and scFv antibodies were found to be suitable for the detection of AFBi, and the assays were reproducible. (dcu.ie)
Chlorpyrifos-BSA conjugates were produced with different molar substitution ratios, and were used for the development of a competitive ELISA with polyclonal anti-chlorpyrifos antibodies. (dcu.ie)

Primary Antibodies are guaranteed for 1 year from date of receipt. (novusbio.com)

FITC is a commonly used marker for antibodies in immunofluorescent techniques since the conjugation of FITC to proteins is relatively easy and does not, in general, destroy the biological activity of the labeled protein. (novusbio.com)
FITC is widely used as a hapten to label different proteins. (novusbio.com)
Antibodies to FITC are used to identify FITC labeled proteins and as models to study the mechanism of antibody response to a well defined hapten. (anobase.org)
DIG is commonly used as a hapten that is conjugated to proteins to improve immunogenicity. (rndsystems.com)
However, most drugs act as haptens, binding covalently to serum or cell-bound proteins, including peptides embedded in major histocompatibility complex (MHC) molecules. (merckmanuals.com)
The major antibody class found in the blood, IgG, has a remarkable persistence, with a serum half-life of 20-23 days, compared with only hours or a few days for other circulating proteins 5 . (nature.com)
The carrier proteins, once coupled to the peptides, provide these additional motifs and generate a strong antibody response. (gbiosciences.com)
The carrier proteins are coupled to haptens, including peptides and small proteins, with the use of protein cross-linkers. (gbiosciences.com)
Newly produced antibody, like the other plasma proteins, became readily labelled with S35 amino acids within a few hours. (caltech.edu)
Some success has been obtained also in the formation of antibodies from other serum proteins and by other denaturation-renaturation procedures. (caltech.edu)
This technology seeker is not interested in high-affinity antibody technologies for small molecules, but rather for large molecules such as proteins. (farmavita.net)

The predominant antibody is immunoglobulin G (IgG). (medscape.com)

Sanfilippo, F & Scott, DW 1976, ' The Effects of carrier-specific helper T-cell tolerance on antibody avidity in the anti-hapten response ', Cellular Immunology , vol. 21, no. 1, pp. 112-120. (johnshopkins.edu)

Competitive immunoassay-validated hapten-carrier conjugates BSA-Carprofen with anti-Hapten antibody. (genemedi.net)
The hapten hapten-carrier conjugates BSA-Carprofen had been validated with our anti-Hapten antibody Anti-Carprofen mouse monoclonal antibody via competitive ELISA test. (genemedi.net)
Production of hapten-protein conjugates of the organophosphate pesticides chlorpyrifos and pirimiphos, and characterisation of antichlorpyrifos antibodies were also successfully performed. (dcu.ie)

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. (bdbiosciences.com)
The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions. (biolegend.com)

Tumors were pretargeted with the bispecific monoclonal antibody (bs-mAb) G250xDTIn-1 and, 72 h later, mice were injected intravenously with one of both radiolabeled peptides. (snmjournals.org)
Earlier clinical studies reported a high sensitivity of pretargeted immunoscintigraphy using murine or chimeric anticarcinoembryonic antigen (CEA) bispecific antibody (BsMAb) and peptides labeled with 111 In or 131 I in medullary thyroid carcinoma (MTC). (snmjournals.org)
The synthesis and applications of the peptides are gaining increasing popularity as a result of the developments in biotechnology and bioengineering areas and for a number of research purposes including cancer diagnosis and treatment, antibiotic drug development, epitope mapping, production of antibodies, and vaccine design. (intechopen.com)
The use of peptides for the generation of antibodies against specific peptides has become an essential tool in proteomic research. (gbiosciences.com)

These immunogenic variables include the chemical structure, conjugation method, cross-linking between the small molecule and protein carrier, the orientation of the hapten on the carrier protein, and linkers used. (prosci-services.com)
Some protein and large polypeptide drugs (eg, insulin , therapeutic antibodies) can directly stimulate antibody production. (merckmanuals.com)
The binding makes the protein-drug complex immunogenic, stimulating antidrug antibody production, T-cell responses against the drug, or both. (merckmanuals.com)
2) I do not know how you are attaching the hapten to the carrier protein. (bio.net)
Passively administered homologous antibody did not produce a change in the retention of the primary injection of antigen nor did secondary injections of a heterologous native protein injected according to the same immunization schedule as the homologous azoprotein. (caltech.edu)
1) The general approach has been to attempt to produce an insoluble protein antigen which would combine specifically with antibody to give a complex that could be dissociated into soluble antibody and insoluble antigen, which could then be separated by centrifugation. (caltech.edu)
However, in every case the resulting product either had lost too much native antigenicity (i.e., adsorbed serum always contained antibody which reacted with native antigen), was too soluble, or had too much power of adsorption for non-specific protein. (caltech.edu)
The basis of hapten- molecular mechanisms of the sensitization pro- protein binding work is the hypothesis that upon cess will result in novel opportunities for the skin absorption, only protein-reactive chemicals development of alternative methods for assessing (or those that can be metabolically or chemically skin sensitization hazard and relative potency of converted to protein-reactive species) are able to chemicals. (cdc.gov)

This need is for a highly sensitive, high-affinity antibody or process of designing and making a substance that works as well as antibodies in having a high affinity to a given analyte, and a high speed of binding. (farmavita.net)
It is important to clarify the methodology that maintains a certain probability of high-affinity antibody production. (farmavita.net)

Due to the hybridoma technology in 1975, monoclonal (murine) antibodies could easily be produced in practical amounts, consequently the number of studies increased drastically. (wikipedia.org)
However, these types of antibodies turned out to be quite troublesome, due to the triggering of the human anti-murine antibody response. (wikipedia.org)
The lack of binding of mIgG to hFcRn explains why murine antibodies are rapidly removed from the circulation in humans, despite long half-life in mice 32 . (nature.com)

The beginning of the pretargeting concept was based on bispecific antibodies which were able to bind a specific target antigen and a radiolabelled hapten. (wikipedia.org)
Haptens may also bind directly to class II MHC molecules, directly activating T cells. (merckmanuals.com)
The sample is incubated with biotinylated Tg and the antibodies of the sample bind the antigen. (cdc.gov)
May I know how the mAb specific for 2, 4-dinitrophenyl (DNP) hapten might also bind to Tyr or phe? (indiabix.com)
however, it is extremely difficult to obtain a pair of antibodies that can bind to a small molecule simultaneously, which is always thought to be a single epitope. (bvsalud.org)

Fluorochrome labeling provides rapid, accurate localization of antigen antibody interaction when one of the reactants is part of a cell, tissue or other biological structure. (novusbio.com)
The specific activity of antibody was measured in the antigen-antibody precipitates obtained, both in the period when the antibody had been allowed to decline and also after antigen had been reinjected to induce an anamnestic response. (caltech.edu)
The biological activity of soluble antigen-antibody complexes: II. (caltech.edu)
2), and ourselves (3) has established the fact that soluble antigen-antibody complexes formed in excess antigen can, (a) induce symptoms similar to anaphylaxis, (b) cause contraction of isolated smooth muscle from normal guinea pigs, and (c) increase the permeability of skin capillaries in a manner similar to that obtained in passive cutaneous anaphylaxis. (caltech.edu)

Mouse monoclonal clone FL-D6 anti-FITC antibody will react with either free or conjugated FITC. (anobase.org)
Mouse monoclonal clone FL-D6 anti-FITC antibody may be used for the detection of FITC and as a universal indicator reagent for bridging FITC with other immunochemical reagents. (anobase.org)

Immunoassays for haptens depend on competitive hapten-anti-hapten reactions, and consequently their sensitivities are significantly influenced by the affinities of anti-hapten antibodies. (lu.se)

Immunogen and coating antigen were prepared by conjugating hapten, 4-(3-oxo-3-(2,6-dihydroxy-4-glucoside phenyl)propyl) benzoic acid, to thyroglobulin and bovine serum albumin, respectively. (cdc.gov)

Serum samples were then taken at various intervals and the specific activity of antibody was measured as soon as antibody reappeared in the circulation. (caltech.edu)
Quantitative antibody nitrogen data, obtained for the serum of each rabbit showed, in general, an inverse relationship between circulating antibody and radioactivity retained, i.e. the higher the circulating antibody titer, the lower the retention of radioactivity in liver tissue. (caltech.edu)

Antibodies against small molecule haptens enable robust and rapid detection, monitoring and quantification using assays such as ELISA or IHC/IF. (prosci-services.com)
The optimized ELISA, developed with antibody M6122, gave IC50 values of 27.8 and 21.8 ng/mL for 1 and 2, respectively. (cdc.gov)
The antibodies were also used in the detection of AFBi in spiked grain samples by ELISA and BIAcore. (dcu.ie)

Two-step in vitro antibody affinity maturation enables estradiol-17β assays with more than 10-fold higher sensitivity. (lu.se)

Then, two haptens were designed by introducing spacer arms at the C4â ³-OH and C5-OH of ABM, respectively, aiming to provide the longest epitope distances. (bvsalud.org)

So why aren't there more therapeutic antibodies on the market targeting ion channels? (synabs.be)
In clinical studies we have evaluated a unique monoclonal antibody-based drug delivery system, a bifunctional antibody designed to deliver imaging or therapeutic agents, such as radioisotopes, drugs, or biologics, to tumor cells, while minimizing the dose to normal tissue. (aacrjournals.org)
Antibodies are used extensively in diagnostics and as therapeutic agents. (farmavita.net)

There are many varieties of antibody conjugation technologies available and each has its benefits, though no single one is optimal for every payload and antibody. (stratech.co.uk)

By using the plaque inhibition technique to measure antibody avidity, we found that there appears to be no difference in the avidity of antibody responses to TNP between the SGG-tolerant and control groups when both are challenged with TNP-SGG in CFA. (johnshopkins.edu)
We also made some experiments on the inhibition of precipitation by added haptens, in order to see how great would be the effects of monohaptenic impurities possibly present in the substances studied. (caltech.edu)
Both sets of antibodies were used in the development of competitive ELISA's and also for the development of BIAcore-based inhibition immunoassays. (dcu.ie)

This antibody is routinely tested by flow cytometric analysis. (bdbiosciences.com)
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis . (biolegend.com)

Owing to the high molecular weight of antibodies and the Fc domain of the antibody, a slow clearance from the blood and non-target tissue occurs, which results in low tumour-to-blood and tumour-to-muscle ratios. (wikipedia.org)
This consequently encouraged the development of lower molecular weight antibodies and resulted in the development of minibodies, diabodies, single chain variable fragments (scFv) and single domain fragments (Fv). (wikipedia.org)
Basically I am using a chemical molecule ( molecular weigth of 261 ) to raise the antibodies. (bio.net)
4 The second was the molecular "dip stick" applied to hapten-antibody binding to determine the "depth" of the combining site. (rockychem.com)

Recombinant Monoclonal Antibody. (rndsystems.com)
The work described in this thesis involves the production and characterisation of antibodies and recombinant antibodies to aflatoxin Bi (AFBi), a potent mycotoxin and carcinogen. (dcu.ie)

Autoimmune anti-HIV-1gp120 antibody with antiidiotype-like activity in sera and immune complexes of HIV-1-related immunologic thrombocytopenia. (jci.org)
Autoimmune antiidiotype-like antibody (Ab2) directed against anti-HIV-1gp120 (Ab1) was found in high titer in the sera of 10 consecutive homosexual and 11 narcotic addict HIV-1-related immunologic thrombocytopenia (HIV-1-ITP) patients, was barely detectable in 10 nonthrombocytopenic HIV-1 sero-positive individuals, and was not detectable in 5 normal subjects by use of a solid-phase RIA. (jci.org)

Antibodies were detected with serially diluted Sheep Anti-FITC-PE. (novusbio.com)
There are no reviews for FITC Antibody (NB100-64617). (novusbio.com)
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. (bdbiosciences.com)
The antibody reacts with both free and conjugated fluorescein isothiocyanate (FITC). (anobase.org)
The antibody can also be used to isolate cells that have an FITC-labeled ligand on their surface. (anobase.org)

An isotype control should be used at the same concentration as the antibody of interest. (bdbiosciences.com)
This mouse IgG2b, κ isotype control is a monoclonal antibody, clone 27-35, that is specific for the dansyl (5-[dimethylamino] naphthalene-1-sulfonyl) hapten. (bdbiosciences.com)

Increased antibody formation was not seen in primed CBA mice injected with (CBA × C57B1)F 1 spleen cells, or in normal (CBA × C57B1)F 1 mice injected with primed CBA cells. (karger.com)
After the addition of biotinylated T3 and streptavidin-coated microparticles, the still-free binding sites of the labeled antibody become occupied, with formation of an antibody-hapten complex. (cdc.gov)
However, this treatment did not affect the level of antibody formation to the carrier of the immunizing antigen. (aai.org)
The level may be too low for detection but still significant with respect to antibody formation. (caltech.edu)

Depending on the immunogenicity and desired application of the small molecule, we will develop personalized recommendations for host species and antibody technology. (prosci-services.com)
The presence of dinitrophenyl groups on the immunizing antigen could suppress, partially or completely, the antibody response to p-azophenyl arsonate when this hapten was located on the same molecule. (caltech.edu)

This was found to be true in both the 19 and 7S antibody responses in vivo as well as in an adoptive transfer model. (johnshopkins.edu)

For example, we may recommend rabbits for host species to small molecules due to rabbits' immune system generating a plethora of diverse antibodies. (prosci-services.com)

Two steps of affinity maturation were performed on a "wild-type" scFv (scFv#E4-4) composed of V(H) and V(L) domains from a mouse anti-E(2) antibody (Ab#E4-4). (lu.se)

CBA × C57B1)F 1 mice were primed to the hapten NNP on either of the non-cross-reacting carriers fowl γ -globulin (F γ G) or ovalbumin (OV) and 4 weeks later were given 50 × 10 6 CBA or (CBA × C57B1)F 1 spleen cells. (karger.com)
When challenged on the same day with NNP.F γ G, the two groups of mice undergoing a graft-versus-host reaction (GVHR) showed higher numbers of antibody-producing cells to both NNP and F γ G determinants. (karger.com)
The antibody-forming cells were of host origin, and the effect could be induced by T lymphocytes, not by B. When mice were challenged with NNP.F γ G at various intervals after the induction of GVHR, it was found that by 8 days the increased response was seen only in mice primed to hapten on the heterologous carrier (NNP.OV). (karger.com)
The dansyl (DNS) hapten is not expressed on human cells or human cell lines. (bdbiosciences.com)
This hapten is not expressed on non-human primate cells. (bdbiosciences.com)
These findings appear irreconcilable with the possibility of direct clonal selection of antibody-producing cells by unprocessed antigen. (caltech.edu)
Language": "en", "Country": "XG", "Code": "Storage Conditions (Product)" }, { "Name": "Background Information", "Value": "Human epidermal growth factor receptor 2 (HER2) is a member of the epidermal growth factor subfamily of transmembrane receptor tyrosine kinases that mediate the growth, differentiation, and survival of cells. (roche.com)

Of these 24, 20 (83.3%) were current smokers compared with 133 (48.2%) of 276 without antibody (p less than 0.01), and there was a weaker association with atopy, defined by skin tests with common allergens. (ox.ac.uk)
The T-helper 1 responses are more specific, and the body develops antibodies to these allergens when the T-helper 1 system is activated. (ceufast.com)

Rats rendered tolerant to ultracentrifuged sheep γ-globulin (SGG) have been shown to make a poor anti-trinitrophenyl (TNP)-specific antibody response upon challenge with TNP-SGG in complete Freund's adjuvant (CFA). (johnshopkins.edu)
We have been able to use this carrier-tolerance system in studying specific helper T-cell unresponsiveness to IgG and IgM antibody responses. (johnshopkins.edu)
Eventually, this effect was shown to depend on the presence of a specific antibody against the type b capsule. (medscape.com)
50 μL of sample, a biotinylated monoclonal TSH-specific antibody and a monoclonal TSH-specific antibody labeled with a ruthenium complex react to form a sandwich complex. (cdc.gov)
15 μL of sample and an anti-T3-specific antibody labeled with a ruthenium complex are incubated together. (cdc.gov)
A comparison of antibody-specific activity provided evidence that there was a release of antibody which had been made at the time of S35 feeding and stored in some stabilized form in tissues. (caltech.edu)
From these results it may be concluded that an intracellular antibody-forming activity influences the loss (or retention) of antigen deposited in liver tissue and that the mechanism is immunologically specific. (caltech.edu)
A key issue is how quickly this methodology can determine/calculate the appropriate antibody design for a specific antigen. (farmavita.net)

Hapten-heterologous carrier recall of antihapten was successful as early as 37 days and as late as 11 months after sensitization. (caltech.edu)

In addition, studies on the maturation of 19 and 7S antibody responses showed no differences in antibody avidity between carrier-tolerant and control groups. (johnshopkins.edu)

While investigating the pathogenesis of experimental nephritis produced by rabbit anti-rat-kidney antibody, it occurred to us that the effects of antikidney antibody on kidney tissue might readily be visualized in tissue cultures. (caltech.edu)

Also connecting two haptens via a two amino acid linker resulted in an enhancement effect of the affinity, which improved the uptake and retention of the radiolabelled compound without affecting the rapid clearance. (wikipedia.org)

It can also be conjugated to nucleic acids or saccharides as a label for detection with anti-DIG antibodies. (rndsystems.com)

The antibody does not react with bound or free TRITC (tetramethylrhodamine isothiocyanate). (anobase.org)
Clone HI98 has been described to specifically react with 3-fucosyl-N-acetyllactosamine (3-FAL), also called X-hapten, SSEA-1, CD15, or Lewis X. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections 5 and formalin-fixed paraffin-embedded tissue sections. (biolegend.com)

Infants rarely responded to PRP vaccine, but both the proportion of responders and resultant antibody levels improved dramatically in those aged 1-2 years. (medscape.com)

Antibodies raised in rabbits M6122, M6123, and M6124 and the coating antigen were screened and characterized to determine their optimum concentrations. (cdc.gov)

Altogether, the study provided a theoretical foundation as well as practical experience and demonstrated the importance of careful hapten design and extensive antibody screening to successfully establish the sandwich immunoassay for small molecules. (bvsalud.org)

To bypass the problem associated with the prolonged circulation time of radiolabelled antibodies, in the mid-1980s a strategy called pretargeted radioimmunotherapy was developed. (wikipedia.org)

After the addition of anti-Tg antibodies labeled with ruthenium complex and streptavidin-coated microparticles, the immunocomplex produced becomes bound to the solid phase via interaction of biotin and streptavidin. (cdc.gov)

For the past several years we have been interested in devising methods that would afford practical procedures for the isolation and purification of antibodies from immune serums and in particular the isolation of non-precipitating antibodies from animal serums and allergic antibodies (reagins) from human serums. (caltech.edu)

In the present study, abamectin (ABM) was selected to prove the effect of hapten design and antibody recognition properties on the development of a sandwich immunoassay for small molecules. (bvsalud.org)

Anatomy14

Organisms9

Diseases4

Chemicals and Drugs89

Analytical, Diagnostic and Therapeutic Techniques and Equipment37

Phenomena and Processes27

Disciplines and Occupations2

Information Science3

Health Care4

Monoclonal antibodies7

Conjugate7

Antigens8

Specificity7

Assay3

Polyclonal4

Primary Antibodies1

Proteins11

Immunoglobulin1

Anti-hapten response1

Conjugates3

Affinity chromatography2

Peptides4

Protein8

High affinity2

Murine3

Bind5

Antigen antibody4

Mouse monoclonal2

Reactions1

Immunogen1

Serum2

ELISA3

Assays1

Epitope1

Therapeutic3

Conjugation1

Inhibition3

Flow cytometric analysis2

Molecular4

Recombinant2

Autoimmune2

FITC5

Isotype2

Formation4

Molecule2

Vivo1

Species1

ScFv1

Cells7

Allergens2

Specific8

Antihapten1

Responses1

Rabbit1

Amino1

Detection1

React2

Vaccine1

Rabbits1

Successfully1

Circulation1

Complex1

Human1

Small1