• Hantaviruses such as Hantaan virus (HTNV) and Andes virus cause two human diseases, hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome, respectively. (mssm.edu)
  • Previously, two well-characterized hantaviruses had been isolated from different species in the United States: Seoul virus from Rattus norvegicus (Norway rat) and Prospect Hill virus from Microtus pennsylvanicus (meadow vole) (5). (cdc.gov)
  • Severe infections with hantaviruses HTNV, Dobrava-Belgrade virus (DOBV), or PUUV are characterized by AKI with massive proteinuria. (biomedcentral.com)
  • After finding the virus, the group cloned and sequenced it and compared it with known hantaviruses. (sciencedaily.com)
  • The new virus shares approximately 75 percent of its nucleotides and 85 percent of its amino acids with Asian and European hantaviruses. (sciencedaily.com)
  • Hantaviruses occur throughout the world in wild rodents, which shed the virus throughout life in saliva, urine, and feces. (msdmanuals.com)
  • Dobrava-Belgrade virus (DOBV) and Hantaan virus (HTNV) hantaviruses cause hemorrhagic fever with renal syndrome (HFRS). (reagena.com)
  • Within a few years, 4 additional disease-associated hantaviruses indigenous to the United States were described: Bayou, Black Creek Canal, New York, and Monongahela viruses. (medscape.com)
  • Hantaviruses (family Bunyaviridae , genus Hantavirus ) are rodent- and insectivore-borne viruses that are distributed in all continents except Antarctica. (medscape.com)
  • [ 5 ] All known New World hantaviruses pathogenic to humans, including SNV and Andes virus, cause HPS, in which the primary organ affected is the lungs. (medscape.com)
  • These rodents are a nuisance, but they also pose a more serious health risk: the spread of viruses such as the hantaviruses. (geometry.net)
  • αVβ3 integrin is generally known as the primary endocytic receptor for pathogenic hantaviruses which include: HTNV Seoul virus (SEOV) PUUV SNV and New York-1 virus (NYV) [18]. (biotech2012.org)
  • Zhang, Yun-Zhi title: Fugong virus, a novel hantavirus harbored by the small oriental vole (Eothenomys eleusis) in China date: 2016-02-16 journal: Virol J DOI: 10.1186/s12985-016-0483-9 sha: 7dad7185f2f7dd28cfaa251822682e46bb5b26e6 doc_id: 2125 cord_uid: xbpko2bt BACKGROUND: Rodents are natural reservoirs of hantaviruses, which cause two disease types: hemorrhagic fever with renal syndrome in Eurasia and hantavirus pulmonary syndrome in North America. (distantreader.org)
  • Puumala virus is found in Scandinavia, western Europe, and western Russia. (cdc.gov)
  • Hantaan and Dobrava virus infections usually cause severe symptoms, while Seoul, Saaremaa, and Puumala virus infections are usually more moderate. (cdc.gov)
  • Fatality ranges from 5-15% for HFRS caused by Hantaan virus, and it is less than 1% for disease caused by Puumala virus. (cdc.gov)
  • We analyzed the cellular consequences of hantavirus infection by measuring adhesion and migration capacity of human renal cells infected with Puumala (PUUV) or Hantaan (HTNV) virus. (biomedcentral.com)
  • Over the ensuing years, several other etiologic agents of HFRS such as the Seoul, Puumala, and Dobrava viruses, were discovered across Europe and Asia. (medscape.com)
  • Description: Puumala virus (PUUV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) and is highly homologous to the protype hantavirus Hantaan virus (1). (mytaq.com)
  • Milder forms are caused by SEOUL VIRUS and transmitted by the rodents Rattus rattus and R. norvegicus, and the PUUMALA VIRUS with transmission by Clethrionomys galreolus. (ucdenver.edu)
  • De indfangede IgM-antistoffer påvises af HRP (peberrodsperoxidase) enzymet, som er koblet til det rekombinante Puumala-virus nukleokapsidprotein. (aidian.dk)
  • Some forms of hemorrhagic fever with renal syndrome are mild (eg, nephropathia epidemica, caused by Puumala virus, as occurs in Scandinavia, the western part of the former Soviet Union, and Europe). (msdmanuals.com)
  • Hantaan, Dobrava, Seoul, and Puumala viruses) cause hemorrhagic fever and renal syndrome (HFRS), in which the primary organ affected is the kidney. (medscape.com)
  • Mortality rate patterns for hemorrhagic fever with renal syndrome caused by Puumala virus. (geometry.net)
  • Active surveillance of patients with HFRS entails 1) recovering whole-genome sequences of Hantaan virus (HTNV) using amplicon (multiplex PCR-based) next-generation sequencing, 2) tracing the putative infection site of a patient by administering an epidemiological questionnaire, and 3) collecting HTNV-positive rodents using targeted rodent trapping. (korea.ac.kr)
  • Researchers in the West African country of Guinea have discovered the first African hantavirus, a type of rodent- borne virus that can cause life-threatening infections in humans. (sciencedaily.com)
  • Researchers have discovered the first African hantavirus, a type of rodent-borne virus that can cause life-threatening infections in humans when it is inhaled through aerosolized rodent urine or droppings. (sciencedaily.com)
  • This novel hantavirus is related to viruses that cause severe disease in humans in Central and Eastern Europe. (sciencedaily.com)
  • The American virus causes hantavirus pulmonary syndrome: fever, chills, and severe muscle pain, followed by respiratory distress. (sciencedaily.com)
  • in 1976, the first hantavirus was found near-and named for-the Hantaan River near Seoul, South Korea. (sciencedaily.com)
  • We don't yet know what symptoms the Sangassou virus might cause or how virulent it is," said ter Meulen, "but we have already obtained preliminary evidence that the Sangassou virus can infect humans, because we identified hantavirus-specific neutralizing antibodies in [the blood] of humans living in the area where the virus was detected. (sciencedaily.com)
  • Like each of the more than two dozen other types of hantavirus, Sangassou virus is carried by only one host species-limiting its spread to the natural range of the African wood mouse, from southern Guinea across parts of Sierra Leone, Liberia, and Ivory Coast, to Ghana. (sciencedaily.com)
  • Serum samples from those afflicted demonstrated evidence of Hantavirus infection and within 10 weeks of the original outbreak, researchers had successfully developed a diagnostic test for the virus. (medscape.com)
  • The clinical syndrome caused by Sin Nombre virus (SNV) became known as Hantavirus pulmonary syndrome (HPS) or, more accurately, Hantavirus cardiopulmonary syndrome (HCPS). (medscape.com)
  • About 20 viruses have been identified within the genus Hantavirus, family Bunyaviridae, but only 11 have been shown to cause human disease. (medscape.com)
  • Description: Andes virus (ANDV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). (mytaq.com)
  • Description: Hantaan virus (HNTV) is the prototype virus of the genus hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA virus that is the eiological agent of Korean hemorrhagic fever (1). (mytaq.com)
  • Довідковий матеріал загального характеру Bunyaviridae contain the genus Hantavirus , which consists of at least 4 serogroups with 9 viruses causing 2 major, sometimes overlapping, clinical syndromes: Hemorrhagic fever. (msdmanuals.com)
  • Andes virus is the only person-to-person transmittable hantavirus. (reagena.com)
  • 1,2 In Mainland China, there are two predominant species of Hantavirus, Hantaan and Seoul virus, and either or both species may circulate in a given area. (who.int)
  • Most hantavirus infections are caused by Sin Nombre virus, but cases of HPS caused by Bayou, Black Creek Canal, Monongahela, and New York viruses have been reported, and cases of domestically acquired hemorrhagic fever and renal syndrome caused by Seoul virus have also occurred. (medscape.com)
  • [ 10 ] The only hantavirus species with evidence of human-to-human transmission is Andes virus, which is endemic to South America. (medscape.com)
  • The deer mouse may develop chronic hantavirus infection and shed virus in its Serologic testing for hantavirus is available at the Hygienic Laboratory. (geometry.net)
  • The new agent was named the Sin Nombre virus and it is associated with hantavirus pulmonary syndrome (HPS). (geometry.net)
  • This virus is phylogenetic clustering with another hantavirus LX309, but shows highly genomic divergence. (distantreader.org)
  • In this study, we identified another novel hantavirus in the small oriental vole (Eothenomys eleusis, subfamily Arvicolinae), designated Fugong virus (FUGV) because it was recovered in Fugong county, Yunnan Province, China. (distantreader.org)
  • The new virus went through a litany of names (eg, Little Water virus, Four Corners virus, Muerto Canyon virus) before finally being given the somewhat tongue-in-cheek moniker of Sin Nombre virus (in Spanish, literally the virus with no name). (medscape.com)
  • It was isolated from an infected Oligoryzomys longicaudatus rodent in Chile, and is highly similar to the Sin Nombre virus (SNV). (mytaq.com)
  • Sin Nombre Virus Infection in Field Workers, Colorado, USA. (impeckoble.com)
  • Serologic diagnosis in North America must be able to differentiate between Seoul and Sin Nombre virus infections due to potential cross-reactivity. (msdmanuals.com)
  • Peptide antagonists that inhibit Sin Nombre virus and hantaan virus entry through the beta3-integrin receptor. (mahavirelectricalsfurnitures.com)
  • Others are severe (eg, that caused by Hantaan virus, as occurs in Korea, China, and Russia, or by Dobrava [Belgrade] virus, as occurs in the Balkans). (msdmanuals.com)
  • however, the Black Creek Canal virus and the Bayou virus of the southeastern United States, as well as the Andes virus of South America, have been linked to renal failure and share some similarities with HFRS. (medscape.com)
  • Human-to-human transmission can occur with Andes virus. (msdmanuals.com)
  • People can become infected with these viruses and develop HFRS after exposure to aerosolized urine, droppings, or saliva of infected rodents or after exposure to dust from their nests. (cdc.gov)
  • Depending upon which virus is causing the HFRS, death occurs in less than 1% to as many as 15% of patients. (cdc.gov)
  • HFRS varies considerably in its symptoms and severity depending on the causative virus species. (biomedcentral.com)
  • The clinical syndrome became known as hemorrhagic fever with renal syndrome (HFRS), formerly Korean hemorrhagic fever, and the virus was named Hanta after the Hantaan River of Korea. (medscape.com)
  • Dive into the research topics of 'Hantaan virus nucleocapsid protein binds to importin α proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor kappa B'. Together they form a unique fingerprint. (mssm.edu)
  • It indicated that linkage of Hsp70 to NP enhanced the immune response to Hantaan virus nucleocapsid protein. (virosin.org)
  • Antibodies reactive with these viruses have been detected in serum specimens from rodents and humans from many areas of the United States (5). (cdc.gov)
  • There are 14 distinct viruses associated with haemorrhagic fever in humans. (who.int)
  • the only exception is the four dengue viruses, which may circulate continually among humans. (who.int)
  • The researchers originally collected hundreds of African rodents during a study of the variability of Lassa virus-another rodent-borne virus-in its hosts and in humans. (sciencedaily.com)
  • They include both DNA and RNA viruses as well viruses from humans and animals. (lookformedical.com)
  • Загальні відомості про арбовірусні, аренавірусні та філовірусні інфекції Arbovirus (arthropod-borne virus) applies to any virus that is transmitted to humans and/or other vertebrates by certain species of blood-feeding arthropods, chiefly insects (flies and mosquitoes). (msdmanuals.com)
  • Humans become infected through direct contact with infected rodents or inhalation of virus that has been shed in rodent excreta, blood, and saliva and then become aerosolized. (medscape.com)
  • Haantan virus is widely distributed in eastern Asia, particularly in China, Russia, and Korea. (cdc.gov)
  • They named the disease the Hantaan virus, after a river near the demilitarized zone in Korea, the area of much fighting over hills and bunkers during the later stages of the Korean War. (wearethemighty.com)
  • As a group, they are still commonly referred to as the Bunyaviridae family of viruses, or simply bunyaviruses. (medscape.com)
  • These febrile diseases result from infection by viruses from 4 viral families: Arenaviridae, Bunyaviridae, Filoviridae, and Flaviviridae. (medscape.com)
  • and the yellow-necked field mouse ( Apodemus flavicollis ), which carries Dobrava virus. (cdc.gov)
  • The most severe form is caused by HANTAAN VIRUS whose natural host is the rodent Apodemus agrarius. (ucdenver.edu)
  • Two Hantaan virus strains, clone 1 (cl-1), which is virulent in newborn mice, and its attenuated mutant (mu11E10), were used to examine the pathogenesis of Hantaan virus infection in a mouse model and identify virus factors relating to virulence. (elsevierpure.com)
  • Such viruses are produced in cells coinfected with different strains of a given virus. (lookformedical.com)
  • Hepatitis E virus (HEV), an important agent of viral hepatitis worldwide, can cause severe courses of infection in pregnant women and immunosuppressed patients. (mdpi.com)
  • Some of these viruses cause relatively mild illnesses, while others can cause severe, life-threatening disease. (who.int)
  • Recovery of infectious virus between 10 and 20 days after the onset of symptoms has only been documented in some individuals with severe COVID-19 symptoms, in some complicated cases by an immunocompromised condition [ 24 ]. (biomedcentral.com)
  • Some are usually mild but occasionally may be severe (eg, Seoul virus that has world-wide distribution in wild brown and domesticated rats). (msdmanuals.com)
  • African Swine Fever Virus Biology and Vaccine Approaches. (kiev.ua)
  • During viral infections, the complex and dynamic distributions of variants, termed viral quasispecies, play a key role in the adaptability of viruses to changing environments and the fate of the population as a whole. (springer.com)
  • 2003. Ultrastructural differences in mixed infections of six Turnip mosaic virus and one Ribgrass mosic virus isolates in Crucifers. (esciencepress.net)
  • The Virus Glycoprotein Spikes reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (mytaq.com)
  • The Euroinmun Anti Hanta Virus Pool Elisa Igg Seekamp 31 23560 Luebeck Germany reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (nfkb-p65.net)
  • Description: Quantitative sandwich ELISA for measuring Human Anti-Epstein?Barr virus IgG (Anti-EBV IgG) Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. (nfkb-p65.net)
  • Reagena Dobrava-Hantaan IgM EIA er et enzym immunoassay til påvisning af akut Dobrava- og Hantaan-virusinfektion fra humant serum. (aidian.dk)
  • Reagena Dobrava-Hantaan IgG EIA er et enzym immunoassay til påvisning af Dobrava og Hantaan IgG-antistoffer fra humant serum. (aidian.dk)
  • Six rAdeasy-G1 immuned mice and four rAdeasy-G2 immuned mice produce antibody which can specifically react with the Hantaan virus. (virosin.org)
  • Human IgG antibody Laboratories manufactures the virus glycoprotein spikes reagents distributed by Genprice. (mytaq.com)
  • Human IgG antibody Laboratories manufactures the euroinmun anti hanta virus pool elisa igg seekamp 31 23560 luebeck germany reagents distributed by Genprice. (nfkb-p65.net)
  • Since VHF share symptoms with many other diseases, positive identification of the disease relies on laboratory evidence of the viruses in the bloodstream, such as detection of antigens and antibodies or isolation of the virus from the body. (who.int)
  • In 1976, South Korean researcher Dr. Ho Wang Lee and his team discovered the virus was spread from rat saliva, feces and urine. (wearethemighty.com)
  • In order to study the immune responses of Hantaan virus envelope glycoproteins G1 and G2 in adenovirus expression system, G1 and G2 gene were amplified from Hantaan virus 76-118 and cloned to the plasmid pAdTrackCMV. (virosin.org)
  • Virus Helper 0 domande Viruses which enable defective viruses to replicate or to form a protein coat by complementing the missing gene function of the defective (satellite) virus. (lookformedical.com)
  • Virus-induced host gene shutoff in animals and plants. (notulaebotanicae.ro)
  • Recombinant fusion prokaryotic expression vector pGEX-4T-1/hsp70-S was constructed by cloning genes Hsp70 and Hantaan virus S gene coding region into pGEX-4T and was expressed in E. coli. (virosin.org)
  • The aim of the study was development of recombinant positive control containing a fragment of B646L gene of African swine fever virus. (kiev.ua)
  • This one-to-one pairing of virus with host also means that the Sangassou discovery has implications for rodent classification, said ter Meulen. (sciencedaily.com)
  • We are also planning to look for other emerging viruses in our rodent collection," said ter Meulen. (sciencedaily.com)
  • Reliable and rapid diagnostic tests coupled with national surveillance created conditions whereby patients were tested, relevant information was gathered regarding rodent exposures, and potential rodent virus hosts were caught and tested. (medscape.com)
  • These febrile diseases result from infection by enveloped RNA viruses belonging to six taxonomic families: Arenaviridae, Hantaviridae, Nairoviridae, Phenuiviridae, Filoviridae, and Flaviviridae. (medscape.com)
  • After subcutaneous inoculation of newborn BALB/c mice, cl-1 caused fatal disease with high viral multiplication in peripheral organs, but mu11E10 produced nonfatal infection with a low level of virus multiplication. (elsevierpure.com)
  • The severity of the disease varies depending upon the virus causing the infection. (cdc.gov)
  • African Swine Fever (Infection With African Swine Fever Virus). (kiev.ua)
  • The viruses are transmitted by two main categories of natural reservoirs: arthropods and rodents. (medscape.com)
  • These glycoproteins interact with the PUUV nucleocapsid (NP) protein through their cytoplasmic tail, and this association has been suggested to be crucial to the binding of the ribonucleoprotein of the PUUV and the assembly of the virus particle (2). (mytaq.com)
  • Not all viruses in these families cause viral hemorrhagic fever. (medscape.com)
  • However, different viruses can cause a range of various clinical problems in addition to viral hemorrhagic fever. (medscape.com)
  • The viruses are carried by a number of rodents, including the brown rat, the striped field mouse, and the yellow-necked mouse. (sciencedaily.com)
  • To isolate the virus, the team collected blood samples from more than 600 rodents. (sciencedaily.com)
  • 1992. Characterization of distinct isolate of tomato spotted wilt virus TSWV. (esciencepress.net)
  • Quasispecies composition and evolution of a typical Zika virus clinical isolate from Suriname. (cdc.gov)
  • Virus Incompleti 0 domande Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. (lookformedical.com)
  • 1993. The serological comparison of tospovirus isolates from Taiwan and India with Impatiens necrotic spot virus and different tomato spotted wilt virus isolates. (esciencepress.net)
  • Moreover, viral genome tracking has been recently performed to rapidly and precisely characterize an outbreak from the emerging virus. (korea.ac.kr)
  • Provirus 0 domande Duplex DNA sequences in eukaryotic chromosomes, corresponding to the genome of a virus, that are transmitted from one cell generation to the next without causing lysis of the host. (lookformedical.com)
  • Virus Riassortanti 0 domande Viruses containing two or more pieces of nucleic acid (segmented genome) from different parents. (lookformedical.com)
  • Virus Delle Piante 0 domande Viruses parasitic on plants higher than bacteria. (lookformedical.com)
  • After amplification in the 293 cell, the recombinant viruses were immuned to the Balb/c mice. (virosin.org)
  • An experiment with genetic reassortant viruses showed that in newborn mice the M segment is the most related to virulence and the L segment is partly related. (elsevierpure.com)
  • Others, called SATELLITE VIRUSES, are able to replicate only when their genetic defect is complemented by a helper virus. (lookformedical.com)
  • Virus A Rna 0 domande Viruses whose genetic material is RNA. (lookformedical.com)
  • 2002. Genetic organization of Iris yellow spot virus M RNA: indications for functional homology between the Gc. (esciencepress.net)
  • Genetic and Immunogenic Characteristics of Measles Virus Isolated in Zhejiang Province[J]. Virologica Sinica, 2006, 21(1): 1-5. (virosin.org)
  • Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples. (cdc.gov)
  • Dobrava virus is found primarily in the Balkans, and Seoul virus is found worldwide. (cdc.gov)
  • Most cases are attributable to the Seoul virus, with the Hantaan virus playing a more minor role. (medscape.com)
  • 3,4 This dynamic type of epidemiology is characterized by co-circulation of both viruses with a predominance of Hantaan virus in north-eastern China and a predominance of Seoul virus south-western China. (who.int)
  • Viral hemorrhagic fevers share certain clinical manifestations, regardless of the virus that causes the disease. (medscape.com)
  • Despite the diverse taxonomy of the six virus families involved in viral hemorrhagic fevers (VHFs), they share some common characteristics. (medscape.com)
  • On the contrary, current evidence indicates that mutant spectra contribute to viral pathogenesis, can modulate the expression of phenotypic traits by subpopulations of viruses, can include memory genomes that reflect the past evolutionary history of the viral lineage, and, furthermore, can participate in viral extinction through lethal mutagenesis. (springer.com)
  • Arias A, Agudo R, Ferrer-Orta C, Pérez-Luque R, Airaksinen A, Brocchi E, Domingo E, Verdaguer N, Escarmis C (2005) Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding. (springer.com)
  • Charpentier C, Dwyer DE, Mammano F, Lecossier D, Clavel F, Hance AJ (2004) Role of minority populations of human immunodeficiency virus type 1 in the evolution of viral resistance to protease inhibitors. (springer.com)
  • Here, we reviewed genomic epidemiological and active surveillance data for determining the emergence of zoonotic RNA viruses based on viral genomic sequences obtained from patients and natural reservoirs. (korea.ac.kr)
  • However, RNase A treatment of positive samples prior to RNA extraction did not degrade viral RNA, indicating the presence of SARS-CoV-2 nucleocapsids or complete virus particles protecting the RNA as opposed to free viral RNA. (biomedcentral.com)