• Corynebacterium efficiens is a thermotolerant, glutamic acid-producing (from dextrin) species of bacteria from soil and vegetables. (wikipedia.org)
  • An easily transferable metabolic engineering strategy for access of C. glutamicum to aldohexuronates was developed and applied to growth and production of the amino acids L-lysine and L-ornithine as well as the terpene lycopene from D-galacturonate or D-glucuronate. (springeropen.com)
  • Metabolic network analysis during fed-batch cultivation of Corynebacterium glutamicum for pantothenic acid production: first quantitative data and analysis of by-product formation. (microbiologyresearch.org)
  • Since its discovery, C. glutamicum has become an indispensable microorganism for the biotechnological industry [ 9 ]. (springeropen.com)
  • Neither aldohexuronic acid supported growth of C. glutamicum as sole or combined carbon source, although its genome encodes a putative uronate isomerase sharing 28% identical amino acids with UxaC from Escherichia coli . (springeropen.com)
  • Identification, sequence analysis, and expression of a Corynebacterium glutamicum gene cluster encoding the three glycolytic enzymes glyceraldehyde-3-phosphate dehydrogenase, 3-phosphoglycerate kinase, and triosephosphate isomerase. (microbiologyresearch.org)
  • Utilization of the hexuronic acids D-galacturonic acid (abundant in pectin-rich waste streams such as peels and pulps) and D-glucuronic acid (a component of the side-chains of plant xylans) for growth and production with C. glutamicum has not yet been studied. (springeropen.com)
  • Heterologous expression of the genes for both uptake and catabolism of D-galacturonic acid and D-glucuronic acid was required to enable growth of C. glutamicum with either aldohexuronic acid as the sole carbon source. (springeropen.com)
  • Corynebacterium glutamicum , which is used in industrial amino acid production at a million-ton scale, has been engineered towards utilization of alternative carbon sources. (springeropen.com)
  • Recently, efforts with C. glutamicum have shifted from optimizing production processes to also include access to alternative carbon sources. (springeropen.com)
  • Corynebacterium glutamicum is a nonpathogenic gram-positive bacterium used as an important industrial strain for amino acid, nucleic acid, organic acid, alcohol, and biopolymer production and is a key model organism for studying pathogen evolution, such as Corynebacterium diphtheriae and Mycobacterium tuberculosis , which are phylogenetically related to C. glutamicum [ 5 ]. (biomedcentral.com)