Hallmark details of cellular senescence. Medical search. Frequent questions

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Anatomy32

Telomere Fibroblasts Cells, Cultured Cell Line, Tumor Cell Line Heterochromatin Plant Leaves Foreskin HCT116 Cells Cell Line, Transformed Intranuclear Inclusion Bodies Embryo, Mammalian Endothelial Cells Epithelial Cells Cell Nucleus Mitochondria Melanocytes HeLa Cells Human Umbilical Vein Endothelial Cells NIH 3T3 Cells Keratinocytes Skin Stem Cells Chromatin Lung Tumor Cells, Cultured Mesenchymal Stromal Cells Bile Ducts Flowers Hep G2 Cells Prostate Liver

Organisms9

Mice, Knockout Mice, Inbred C57BL Mice, Transgenic Mice, Nude Arabidopsis Mice, Mutant Strains Plants, Genetically Modified Petunia Mice, Inbred BALB C

Diseases18

Aging, Premature Cell Transformation, Neoplastic Neoplasms Progeria Werner Syndrome Nevus, Pigmented Genomic Instability Disease Models, Animal Atherosclerosis Prostatic Neoplasms Airway Remodeling Inflammation Melanoma Skin Neoplasms Liver Cirrhosis, Biliary Cell Transformation, Viral Disease Progression Breast Neoplasms

Chemicals and Drugs96

Cyclin-Dependent Kinase Inhibitor p16 Tumor Suppressor Protein p53 Cyclin-Dependent Kinase Inhibitor p21 Telomerase beta-Galactosidase Retinoblastoma Protein Tumor Suppressor Proteins Tumor Suppressor Protein p14ARF Sirtuin 1 Nuclear Proteins RNA, Small Interfering Reactive Oxygen Species Telomeric Repeat Binding Protein 2 Heterochromatin DNA-Binding Proteins Hydrogen Peroxide ras Proteins Transcription Factors Repressor Proteins Oxidants Cell Cycle Proteins Histones TOR Serine-Threonine Kinases Proto-Oncogene Proteins c-myc RNA, Messenger Cyclin-Dependent Kinase Inhibitor p15 Polycomb Repressive Complex 1 Inhibitor of Differentiation Protein 1 Protein-Serine-Threonine Kinases MicroRNAs Sirtuins Toyocamycin Jumonji Domain-Containing Histone Demethylases Cyclin-Dependent Kinase Inhibitor p27 Isopropyl Thiogalactoside Biological Markers Antigens, Nuclear Cyclin-Dependent Kinase 6 Proto-Oncogene Proteins c-mdm2 Neoplasm Proteins Papillomavirus E7 Proteins Ataxia Telangiectasia Mutated Proteins DNA Proto-Oncogene Proteins p21(ras)RecQ Helicases Intracellular Signaling Peptides and Proteins Cyclin-Dependent Kinase 4 PTEN Phosphohydrolase Caveolin 1 E2F Transcription Factors Sirolimus RNA Chlorophyll Histone Deacetylase 1 Doxorubicin Proteasome Endopeptidase Complex Antineoplastic Agents Ethylenes p38 Mitogen-Activated Protein Kinases Chromosomal Proteins, Non-Histone Proto-Oncogene Proteins Cyclins Phosphatidylethanolamine Binding Protein Imidazoles DNA Primers Acetylcysteine Chromatin Trans-Activators Ubiquitin-Protein Ligases Oncogene Proteins, Viral Enzyme Inhibitors Proteins Proto-Oncogene Proteins c-akt Antibiotics, Antineoplastic Cyclin-Dependent Kinases Exodeoxyribonucleases Plant Proteins Carrier Proteins Antioxidants Histone Deacetylases Plant Growth Regulators Piperazines Arabidopsis Proteins Protein Isoforms Cyclin D1 Superoxide Dismutase ADP-Ribosylation Factors Etoposide Cytokinins Histone Deacetylase Inhibitors NF-kappa B Extracellular Signal-Regulated MAP Kinases Protein Kinases Phosphatidylinositol 3-Kinases Oxygen Cyclopentanes

Analytical, Diagnostic and Therapeutic Techniques and Equipment22

Models, Biological Gene Knockdown Techniques Blotting, Western Reverse Transcriptase Polymerase Chain Reaction Transfection Immunohistochemistry Gene Expression Profiling Immunoblotting Chromatin Immunoprecipitation Flow Cytometry Disease Models, Animal Real-Time Polymerase Chain Reaction Microscopy, Fluorescence Cell Culture Techniques Microarray Analysis Oligonucleotide Array Sequence Analysis Caloric Restriction Karyotyping In Situ Hybridization, Fluorescence Fluorescent Antibody Technique Cell Count Polymerase Chain Reaction

Phenomena and Processes76

Cell Aging Telomere Telomere Shortening Aging DNA Damage Cell Proliferation Cell Cycle Cell Cycle Checkpoints Signal Transduction Oxidative Stress Longevity Phenotype Apoptosis Gene Expression Regulation Genes, p16 Diploidy RNA Interference Down-Regulation Heterochromatin Cell Division Mutation Up-Regulation Oncogenes Gene Silencing Genes, ras Gene Expression Regulation, Neoplastic Genomic Instability Promoter Regions, Genetic Telomere Homeostasis Time Factors Radiation Transcription, Genetic Genes, p53 Transfection Base Sequence Cell Shape Phosphorylation Gene Expression Epigenesis, Genetic Autophagy Protein Binding Cell Survival Acetylation DNA Repair Stress, Physiological Genes, Tumor Suppressor Cell Differentiation Gamma Rays DNA Methylation Gene Expression Regulation, Plant Mitosis Enzyme Activation Radiation, Ionizing Gene Deletion Amino Acid Sequence Cell Death G1 Phase MAP Kinase Signaling System Chromatin Chromatin Assembly and Disassembly Protein Processing, Post-Translational Airway Remodeling DNA Replication Protein Structure, Tertiary Cell Growth Processes Transcriptional Activation Protein Transport Caloric Restriction Oxidation-Reduction Ultraviolet Rays Wound Healing Cell Count Dose-Response Relationship, Drug CpG Islands Binding Sites Cell Transformation, Viral

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Cell Aging Cyclin-Dependent Kinase Inhibitor p16 Telomere Fibroblasts Tumor Suppressor Protein p53 Aging, Premature Telomere Shortening Cyclin-Dependent Kinase Inhibitor p21 Telomerase beta-Galactosidase Aging DNA Damage Cells, Cultured Cell Proliferation Cell Line, Tumor Retinoblastoma Protein Cell Cycle Cell Cycle Checkpoints Signal Transduction Oxidative Stress Cell Transformation, Neoplastic Cell Line Tumor Suppressor Proteins Tumor Suppressor Protein p14ARF Sirtuin 1 Neoplasms Progeria Longevity Nuclear Proteins RNA, Small Interfering Phenotype Reactive Oxygen Species Telomeric Repeat Binding Protein 2 Apoptosis Gene Expression Regulation Genes, p16 Diploidy RNA Interference Models, Biological Down-Regulation Heterochromatin DNA-Binding Proteins Gene Knockdown Techniques Hydrogen Peroxide Werner Syndrome Cell Division ras Proteins Transcription Factors Mutation Repressor Proteins Up-Regulation Mice, Knockout Plant Leaves Blotting, Western Oncogenes Oxidants Gene Silencing Cell Cycle Proteins Foreskin Histones Nevus, Pigmented TOR Serine-Threonine Kinases Genes, ras HCT116 Cells Mice, Inbred C57BL Gene Expression Regulation, Neoplastic Reverse Transcriptase Polymerase Chain Reaction Genomic Instability Proto-Oncogene Proteins c-myc Cell Line, Transformed RNA, Messenger Cyclin-Dependent Kinase Inhibitor p15 Polycomb Repressive Complex 1 Molecular Sequence Data Inhibitor of Differentiation Protein 1 Promoter Regions, Genetic Intranuclear Inclusion Bodies Telomere Homeostasis Protein-Serine-Threonine Kinases Time Factors MicroRNAs Sirtuins Radiation Transcription, Genetic Genes, p53 Embryo, Mammalian Toyocamycin Transfection Jumonji Domain-Containing Histone Demethylases Endothelial Cells Cyclin-Dependent Kinase Inhibitor p27 Epithelial Cells Base Sequence Cell Shape Phosphorylation Isopropyl Thiogalactoside Biological Markers Antigens, Nuclear Mice, Transgenic Gene Expression

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