EpidermisAppendagesMorphogenesisApocrine sweatDifferentiationKeratinocytesRegenerationScalpForm hair folliclesIndividual hair folliclesTumorsBenignSweatMutationsProliferationMelanocytesCellsSebaceous glandPigmentCystsAlopeciaSkinHistopathologyWhite hairsErythemaGlandsInduceAccumulation of keratinInducesLipidEpitheliumAnagenTelogenRegulatesDormantTransplantsStructuresTissueOutermost layerMelanocyteTissuesReceptorsBarrierFollicularInflammatory reactionGeneticsAcceleratesThicknessIrritationGrowth patternsInductionGrowsCharacteristicsAbnormalities
Epidermis14
- It houses several types of stem cells, which supply the entire hair follicle with new cells, and take part in healing the epidermis after a wound. (wikipedia.org)
- The researchers found that with the start of the hair's growth phase, mutated melanocyte stem cells migrated up the hair follicle and into the epidermis. (nih.gov)
- The polarity of the epidermis is, for example, reflected in controlled changes in cell shape that accompany differentiation, oriented cell division, and the planar orientation of hair follicles and cilia. (uni-koeln.de)
- At about 8% of epidermal cells, melanocytes form the second most numerous cell type in the epidermis. (innerbody.com)
- Langerhans cells are the third most common cells in the epidermis and make up just over 1% of all epidermal cells. (innerbody.com)
- An epidermal nevus (plural: nevi) is an abnormal, noncancerous (benign) patch of skin caused by an overgrowth of cells in the outermost layer of skin ( epidermis ). (medlineplus.gov)
- The epidermis is the top layer of skin which is responsible for pigment, epidermal cells, and proteins. (cosmeticlaserskinsurgery.com)
- The dermis layer is located just beneath the epidermis and contains the dermal cells, blood vessels and nerves, hair follicles and oil glands that are responsible for providing nutrients. (cosmeticlaserskinsurgery.com)
- The follicle resembles a narrow pocket within the skin, as if a tiny finger had pushed the epidermis down into the Dermis and the underlying subcutaneous tissue. (hairscientists.org)
- The arrector pili muscle joins the wall of the follicle to the epidermis and is responsible for the erection of hairs and goose flesh during cold weather or emotional stresses. (hairscientists.org)
- Melanocytes are found in the basal layer of the epidermis and together with the surrounding keratinocytes form the epidermal unit, whose main function is to produce and distribute melanin by a complex process called melanogenesis ( 4-7 ). (spandidos-publications.com)
- The dermis, the second layer of the skin just under the outer layer, the epidermis, contains tens of thousands of tiny and complex structures, the hair follicles, which enclose the hair root. (antiaging-systems.com)
- Teeth, hair, and hair follicles are formed by the epidermis and dermis in concert, while fingernails and toenails are formed by the epidermis alone. (medscape.com)
- Hair follicles, sebaceous glands, sweat glands, apocrine glands, and mammary glands are considered epidermal glands or epidermal appendages, because they develop as downgrowths or diverticula of the epidermis into the dermis. (medscape.com)
Appendages4
- This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. (creativebiomart.net)
- Epidermal appendages are intradermal epithelium-lined structures that can divide and differentiate. (medscape.com)
- Epidermal appendages serve an important role as a source of epithelial cells. (medscape.com)
- The wound heals by means of reepithelialization from the remaining epidermal appendages, similar to the healing of partial-thickness burns. (medscape.com)
Morphogenesis5
- Mitochondrial function in murine skin epithelium is crucial for hair follicle morphogenesis and epithelial-mesenchymal interactions. (nature.com)
- In vitro models of human hair follicle-like tissue could be fundamental tools to better understand hair follicle morphogenesis and hair drug screening. (researchgate.net)
- During prenatal development and postnatal cyclic hair regeneration, hair follicle morphogenesis is triggered by reciprocal interactions and the organization of the epithelial and mesenchymal cell po. (researchgate.net)
- This article will address the importance of polarizing processes and their molecular regulators in epidermal morphogenesis and homeostasis and discuss how alterations in polarity may contribute to skin disease. (uni-koeln.de)
- A conditional knockout in surface epithelium results in defects in hair follicle development and epidermal morphogenesis. (jax.org)
Apocrine sweat1
- Other structures associated with the hair follicle include the cup in which the follicle grows known as the infundibulum, the arrector pili muscles, the sebaceous glands, and the apocrine sweat glands. (wikipedia.org)
Differentiation5
- Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity. (crossref.org)
- Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development. (nature.com)
- The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells. (nature.com)
- Even with HFD feeding in four consecutive days, HFSCs shows increased oxidative stress and the signs of epidermal differentiation. (prohealth.com)
- It contributes to epidermal proliferation, differentiation, and hair growth. (medscape.com)
Keratinocytes4
- Interactions Between Epidermal Keratinocytes, Dendritic Epidermal T-Cells, and Hair Follicle Stem Cells. (ncbs.res.in)
- The local inflammatory reaction following perturbation of the epidermal barrier (either by exposure to a physical or chemical irritant) can appear within minutes to hours after the insult, and is believed to be initiated by the release of primary cytokines from keratinocytes [ 9 10 ]. (ispub.com)
- One group of epidermal nevi, called keratinocytic or nonorganoid epidermal nevi, includes nevi that involve only keratinocytes. (medlineplus.gov)
- Once they reach the stratum corneum, they are fully differentiated keratinocytes devoid of nuclei and are subsequently shed in the process of epidermal turnover. (medscape.com)
Regeneration7
- Hair regeneration using hair follicle stem cells (HFSCs) and dermal papilla cells is a promising approach for the treatment of alopecia. (researchgate.net)
- Dermal papilla cells (DPCs) play critical roles in hair follicle development, but the underlying mechanisms that contribute to hair regeneration have yet to be fully elucidated, particularly in terms of alterations in androgenetic alopecia patients. (researchgate.net)
- Mice on a high-fat diet (which leads to obesity) experience a depletion of hair follicle stem cells through a cascade of inflammatory signaling, which blocks hair follicle regeneration and leads to hair loss. (prohealth.com)
- The authors found that obesity can lead to depletion of hair follicle stem cells (HFSCs) through the induction of certain inflammatory signals, blocking hair follicle regeneration and ultimately resulting in loss of hair follicles. (prohealth.com)
- The inflammatory signals in HFSCs strikingly repress Sonic hedgehog signaling that plays crucial role in hair follicle regeneration in HFSCs. (prohealth.com)
- Dr. Claire Higgins and her colleague Dr. Colin Jahoda have published an overview of hair cloning and the challenges scientists face in attempting to develop hair regeneration therapies for androgenetic alopecia or common balding. (bernsteinmedical.com)
- Anagen: The period of follicle regeneration (folliculo-genesis) with active hair growth. (hairscientists.org)
Scalp15
- For example, terminal hairs grow on the scalp and lanugo hairs are seen covering the bodies of fetuses in the uterus and in some newborn babies. (wikipedia.org)
- Of all mammals, humans have the longest growth phase of scalp hair compared to hair growth on other parts of the body. (wikipedia.org)
- For centuries, humans have ascribed esthetics to scalp hair styling and dressing and it is often used to communicate social or cultural norms in societies. (wikipedia.org)
- In addition to its role in defining human appearance, scalp hair also provides protection from UV sun rays and is an insulator against extremes of hot and cold temperatures. (wikipedia.org)
- Differences in the shape of the scalp hair follicle determine the observed ethnic differences in scalp hair appearance, length and texture. (wikipedia.org)
- For example, the skin of the palms and soles does not have hair follicles whereas skin of the scalp, forearms, legs and genitalia has abundant hair follicles. (wikipedia.org)
- The scalp hair follicle in Caucasians is elliptical in shape and, therefore, produces straight or wavy hair, whereas the scalp hair follicle of people of African descent is more curvy, resulting in the growth of tightly curled hair. (wikipedia.org)
- In this study, we demonstrated that hypoxia-inducible factor-1a (HIF-1a) is suppressed in scalp tissues of androgenetic alopecia patients and potentially associated with hair fol. (researchgate.net)
- This normally happens on the scalp, cheeks, eyebrows and wherever else hair follicles are found. (organicfacts.net)
- 6-9 Cutaneous calcified epidermal cysts have been reported on the scrotum, vulva, scalp, subungual area, breast, and heel, but are most commonly located on the scrotum. (lww.com)
- scalp hairs grow for 2-7 years). (hairscientists.org)
- With the use of a specialist micro surgical needle, your doctor will puncture the scalp and insert each hair graft is inserted at an angle with a specific density to resemble a natural and realistic hair pattern. (hshairclinic.co.uk)
- Similar to an FUE hair transplant procedure, follicular unit transaction works by transplanting hair from one area of the scalp to another. (hshairclinic.co.uk)
- Our team of experts work to delicately replicate the appearance of hair follicles on the scalp or natural hair strokes on the brow area to replicate each individual brow hair. (hshairclinic.co.uk)
- Natural pigments are applied at the epidermal level of the scalp to replicate the appearance of hair follicles or strands. (hshairclinic.co.uk)
Form hair follicles2
- In utero, the epithelium and underlying mesenchyme interact to form hair follicles. (wikipedia.org)
- The first is the difficulty in getting dermal papilla cells in humans to self-aggregate and form hair follicles and the second is the inability, thus far, of scientists to generate normal hairs and follicles. (bernsteinmedical.com)
Individual hair follicles2
- One theory is that surplus skin cells build up around individual hair follicles. (medscape.com)
- With a FUT hair transplant instead of removing and transplanting individual hair follicles and transplanting them a strip of hair is removed from the back of the head. (hshairclinic.co.uk)
Tumors1
- Keratoacanthomas are common benign epidermal tumors characterized by the rapid development of a firm, symmetrical dome-shaped nodule with a horn-filled crater in its center and a tendency for spontaneous regression. (cdlib.org)
Benign1
- Calcified epidermal cysts are rare benign entities that were first described in 1947. (lww.com)
Sweat5
- and the number/density of hair follicles and sweat glands. (cdc.gov)
- The dermis promotes the development and maintains the functional components of skin, such as hair follicles, sweat glands, nerves and blood vessels. (biologists.com)
- Other types of epidermal nevi involve additional types of epidermal cells, such as the cells that make up the hair follicles, the sweat glands, or the sebaceous glands (glands in the skin that produce a substance that protects the skin and hair). (medlineplus.gov)
- Hair is closely associated with sweat gland and sebaceous gland activity. (hairscientists.org)
- however, large radiation doses to the skin can cause permanent hair loss, damaged sebaceous and sweat glands, atrophy, fibrosis, decreased or increased skin pigmentation, and ulceration or necrosis of the exposed tissue. (cdc.gov)
Mutations5
- A rare form of skin cancer may sometimes start with cancer-causing mutations in hair follicle stem cells. (nih.gov)
- To explore this potential origin of melanoma, a team of researchers led by Dr. Mayumi Ito at NYU Langone Health genetically engineered mice with oncogenic gene mutations in the melanocyte stem cells within hair follicles. (nih.gov)
- Mutations in the FGFR3 gene and PIK3CA gene account for about forty percent of keratinocytic epidermal nevi. (medlineplus.gov)
- Mutations in the HRAS gene are found in a majority of people with a nevus sebaceous and are also associated with keratinocytic epidermal nevi. (medlineplus.gov)
- Mutations associated with an epidermal nevus are present only in the cells of the nevus, not in the normal skin cells surrounding it. (medlineplus.gov)
Proliferation3
- Inhibits follicle proliferation, if induced by mitogens. (cdc.gov)
- The steady deterioration of the dermal and epidermal layers of the skin with age is caused by a combination of factors including reduced cellular proliferation and collagen synthesis, extracellular matrix remodeling, and changes in epidermal morphology (Crane 2015). (ernolaszlo.com)
- Epidermal growth factor receptor (EGFR) inhibitors are part of an emerging class of anticancer medicines known as "targeted therapy," which target pathways more specific to neoplastic proliferation than traditional chemotherapeutic agents. (medscape.com)
Melanocytes5
- Melanocyte stem cells, the source of melanocytes, are found in the lower portion of hair follicles. (nih.gov)
- The findings will require confirmation in human studies, but they suggest that melanoma can arise from melanocyte stem cells in hair follicles as well as from melanocytes in skin layers. (nih.gov)
- Greying' of hair is due to the gradual loss of the melanocytes' pigment - melanin. (hairscientists.org)
- In white hairs the melanocytes are absent. (hairscientists.org)
- During this short period of change (approximately 2 weeks) the follicle rests the dermal papilla stops production of new cells, the dentrites and melanocytes contract and melanin production ceases. (hairscientists.org)
Cells27
- Different experimental strategies and approaches to obtain mature hair follicles have been designed based upon current knowledge of the epithelial and dermal cells involved in embryonic hair generation and adult hair cycling, and in the epithelial-mesenchymal interactions among them. (wjgnet.com)
- Although normally dormant, hair follicle stem cells (HFSCs) quickly become activated to divide during a new hair cycle. (nature.com)
- Morris, R. J. & Potten, C. S. Highly persistent label-retaining cells in the hair follicles of mice and their fate following induction of anagen. (nature.com)
- Fuchs, E. The tortoise and the hair: slow-cycling cells in the stem cell race. (nature.com)
- The hair follicle regulates hair growth via a complex interaction between hormones, neuropeptides, and immune cells. (wikipedia.org)
- Ordinarily, hair follicle renewal is maintained by the stem cells associated with each follicle. (wikipedia.org)
- Aging of the hair follicle appears to be primed by a sustained cellular response to the DNA damage that accumulates in renewing stem cells during aging. (wikipedia.org)
- Melanocyte stem cells are found within hair follicles, shown here. (nih.gov)
- These cells are found in the skin, eyes, and hair. (nih.gov)
- By confirming that oncogenic pigment cells in hair follicles are a bona fide source of melanoma, we have a better understanding of this cancer's biology and new ideas about how to counter it," Ito says. (nih.gov)
- They seek to discover the activating signals from the neighboring cells that instruct the stem cells to make hair or repair wounds, and the inhibitory signals that tell them to stop making tissue. (rockefeller.edu)
- This disorder results in irregular sebum production and the consequent infection of the epidermal cells. (organicfacts.net)
- Finally, Merkel cells make up less than 1% of all epidermal cells but have the important function of sensing touch. (innerbody.com)
- High-fat diet feeding accelerates hair thinning by depleting HFSCs that replenish mature cells that grow hair, especially in old mice. (prohealth.com)
- After a dilatation followed by rupture, not only a granulomatous inflammatory process accompanied by the attraction of gigantic cells, partially phagocyting the keratin masses are induced in the hair follicle, but also an inflammatory bacterial process derived from a superinfection, most frequently caused by Staphylococcus aureus and Staphylococcus epidermidis, which are considered to be the main factors in the chemotaxis of neutrophils. (e-ijd.org)
- After an adequate therapy is given, an irreversible alopecia remains, due to the disordered structure of the hair follicle by the infiltration of neutrophils and giant inflammatory cells. (e-ijd.org)
- Having made significant progress in improving this vital communication link between dermal papillae cells, scientists still have to contend with a series of obstacles that stand in the way of a hair cloning therapy for human hair loss. (bernsteinmedical.com)
- This uncontrolled cell division results in overgrowth of skin cells, leading to epidermal nevi. (medlineplus.gov)
- Because the mutation is found in some of the body's cells but not in others, people with an epidermal nevus are said to be mosaic for the mutation. (medlineplus.gov)
- The lower extreme is penetrated by the Dermal Papilla an upward protrusion of connective tissue which produces microscopic cells of several kinds from which the hair is formed and developed by cellular elongation and keratinisation. (hairscientists.org)
- The hair shaft is currently believed to be a dead structure composed of cells which undergo keratinisation after leaving the dermal papilla. (hairscientists.org)
- At the base of each follicle is a bulb-like projection, the dermal papilla , surrounded by the hair matrix, a group of cells which divide to form the major structures of the hair fiber and root. (antiaging-systems.com)
- During the anagen growth phase, stem cells migrate to the hair matrix and divide and differentiate in a process controlled by numerous cytokines produced by the dermal papillae. (antiaging-systems.com)
- Of all androgens, the one that most negatively influences dermal papilla cells to produce follicle-shrinking cytokines is 5-α-dihydrotestosterone (DHT), which is synthesized from testosterone by the enzyme 5-α-reductase. (antiaging-systems.com)
- In an animal study, mice administered DHT exhibited reduced expression of IGF-1, which resulted in a lower number of proliferating cells in hair follicles and decreased hair growth. (antiaging-systems.com)
- Well, we all possess hair follicles, which are skin organs made of epidermal cells. (nmhairreplacementstudio.com)
- At the bottom of hair follicles, where the roots are located, cells made of protein are responsible for hair production. (nmhairreplacementstudio.com)
Sebaceous gland4
- Anatomically, the triad of hair follicle, sebaceous gland and arrector pili muscle make up the pilosebaceous unit. (wikipedia.org)
- Also attached to the follicle is a sebaceous gland, which produces the oily or waxy substance sebum. (wikipedia.org)
- Dilutional effect of increased sebaceous gland activity on the proportion of linoleic acid in sebaceous wax esters and in epidermal acylceramides. (springer.com)
- Each hair-producing follicle with its sebaceous gland is known as a pilo-sebaceous unit. (hairscientists.org)
Pigment2
- The human foetus possesses a covering of fine soft usually pigment free hair. (hairscientists.org)
- Our specialised process deposits tiny amounts of pigment to the recipient area and once applied you'll see realistic results that replicate real hair. (hshairclinic.co.uk)
Cysts2
- It remains unclear whether calcified epidermal cysts are the result of dystrophic calcification of preceding epidermal cysts that are affected by inflammation followed by cystic dilation, calcification, cyst wall rupture, and granulomatous reactions, 1 or if they are truly idiopathic growths without any triggering factor such as foreign body infiltration, metabolic or hormonal disorder, or trauma. (lww.com)
- 2 Calcified epidermal cysts reportedly have an eccrine origin. (lww.com)
Alopecia9
- Well known diseases of the hair follicle include alopecia or hair loss, hirsutism or excess hair growth and lupus erythematosus. (wikipedia.org)
- Although overweight people has higher risk of androgenic alopecia, whether obesity accelerates hair thinning, how and the molecular mechanisms have been largely unknown. (prohealth.com)
- Shedding up to a few dozen hairs a day is normal, but excessive loss, known as alopecia, is a cause for concern. (antiaging-systems.com)
- There are many types of hair loss, the most common of which is androgenetic alopecia , which exhibits as male-pattern baldness in men (a receding hairline at the temples and balding at the top of the head) and female-pattern hair loss in women (a general diffuse thinning of the hair). (antiaging-systems.com)
- As the name implies, androgenetic alopecia is androgen-dependent and heriditary, resulting in the atrophy or miniaturization of predisposed hair follicles and progressive decline in hair density. (antiaging-systems.com)
- Before we discuss how Hair Pro can block the cascade of processes leading to alopecia, let's examine the micro-anatomy of the hair follicle and its key component, the dermal papilla. (antiaging-systems.com)
- 6) In a few fascinating studies, hair growth in humans with alopecia was promoted by inducing IGF-1 production. (antiaging-systems.com)
- 7, 11) Interestingly, another way DHT impacts hair loss besides stimulating the production of alopecia-inducing cytokines is by inhibiting IGF-1 production at the dermal papillae. (antiaging-systems.com)
- People may experience hair loss genetically, as a result of medical treatments like chemotherapy or radiation, or as a result of a medical condition like alopecia. (nmhairreplacementstudio.com)
Skin15
- Loss of hair follicles caused by injuries or pathologies affects the patients' psychological well-being and endangers inherent functions of the skin. (wjgnet.com)
- The hair follicle is an organ found in mammalian skin. (wikipedia.org)
- This muscle is responsible for causing the follicle lissis to become more perpendicular to the surface of the skin, and causing the follicle to protrude slightly above the surrounding skin (piloerection) and a pore encased with skin oil. (wikipedia.org)
- Major changes in the skin, including hair loss. (cdc.gov)
- Keratosis pilaris (KP) is a genetic disorder of keratinization of hair follicles of the skin. (medscape.com)
- In these patients, the process of keratinization (the formation of epidermal skin) is faulty. (medscape.com)
- They can contain multiple structures in the skin, including sebaceous glands, hair follicles, and other structures derived from the ectoderm. (aafp.org)
- The integumentary system is an organ system consisting of the skin, hair, nails, and exocrine glands. (innerbody.com)
- Hair and nails extend from the skin to reinforce the skin and protect it from environmental damage. (innerbody.com)
- Higgins and Jahoda describe how it has been known for decades, through the work of Lille and Wang and others, that rat dermal papillae self-organize into new hair-producing follicles when they are injected or grafted into the skin. (bernsteinmedical.com)
- Often, keratinocytic epidermal nevi follow a pattern on the skin known as the lines of Blaschko. (medlineplus.gov)
- Avoiding excess weight, keeping in shape, and discouraging wrinkles by maintaining skin quality are all essential for a years-younger exterior, and, as we will discuss in this article, so is reducing or eliminating hair loss. (antiaging-systems.com)
- Side effects include nausea, picture of Folliculitis An infection of the hair follicles of the skin. (njacs.org)
- Because EGFR is preferentially expressed in epithelial tissues, including the skin and hair follicle, cutaneous side effects of these agents are quite common. (medscape.com)
- The support the concept that skin may be an important site of ex- dermis layer of the skin contains the hair follicles, lymphatic and posure for certain occupational and environmental allergens. (cdc.gov)
Histopathology1
- Histopathology showed epidermal endophytic proliferations under a pronounced hyperparakeratosis. (cdlib.org)
White hairs1
- Ladies especially seem to like what's known as the "salt-n-pepper" look where a man with dark colored hair has some gray or white hairs on the sides. (nmhairreplacementstudio.com)
Erythema2
- Often, patients develop mild erythema around the hair follicles, which is indicative of the inflammatory condition. (medscape.com)
- We found that the drug loaded and blank liposomal gels caused no significant epidermal irritation and erythema. (ispub.com)
Glands1
- The higher the density of the hair, the more sebaceous glands that are found. (wikipedia.org)
Induce4
- Finally, we identify small molecules that increase lactate production by stimulating Myc levels or inhibiting Mpc1 carrier activity and can topically induce the hair cycle. (nature.com)
- While multiple efforts to induce dermal papillae to form new hair follicles have failed, the research that Higgins and Jahoda have published on hair follicle neogenesis has resulted in a new technique to do just that. (bernsteinmedical.com)
- The success of the 3-D culturing of dermal papillae to induce hair follicle neogenesis was a breakthrough in that the scientists have found a way to improve the intercellular communication that is essential to inducing follicle growth. (bernsteinmedical.com)
- however, in response to particular androgens, and in certain areas, such as the sides and top of the head, some cytokines induce follicle atrophy, leading to hair thinning and eventual loss. (antiaging-systems.com)
Accumulation of keratin1
- The main reason is considered to be the disordered keratinization and further occlusion and accumulation of keratin at the hair follicle. (e-ijd.org)
Induces1
- This complex interaction induces the hair follicle to produce different types of hair as seen on different parts of the body. (wikipedia.org)
Lipid1
- It is also clear that psychological stressors lead to aberrant barrier function, with decreased epidermal lipid and structural protein synthesis, decreased hydration of the stratum corneum, and increased transepidermal water loss (Maarouf 2019), and can also result in immune system dysfunction leading to systemic and local inflammation (Liu 2017). (ernolaszlo.com)
Epithelium1
- In addition to laminated layers of keratinous material, the cavity is filled with amorphous basophilic calcareous sediment ( Fig. 1 A). The cyst wall consists of thinned stratified squamous epithelium similar to the hair follicle infundibulum, which is surrounded by fibrosis ( Fig. 1 B). Active inflammation is sometimes seen around the cyst. (lww.com)
Anagen6
- The process of hair growth occurs in distinct sequential stages: anagen is the active growth phase, catagen is the regression of the hair follicle phase, telogen is the resting stage, exogen is the active shedding of hair phase and kenogen is the phase between the empty hair follicle and the growth of new hair. (wikipedia.org)
- Normal hair follicles undergo periods of growth (Anagen) followed by regression (Catagen), resting (Telogen) and evacuation (Exogen) followed by regenesis ('new' Anagen). (hairscientists.org)
- Hairs in the anagen phase may grow faster during the early years. (hairscientists.org)
- The follicle remains quiescent in its shortened state and awakens to regenerate with the onset of the new Anagen phase. (hairscientists.org)
- Whereas hairs may be shed at any stage of the cycle, the majority of shedding occurs during the 'new' Anagen phase. (hairscientists.org)
- A third growth factor, VEGF, is essential for establishing a highly developed blood vessel network around the hair follicle dermal papillae during the anagen growth phase. (antiaging-systems.com)
Telogen2
- Telogen: the resting phase of the follicle which lasts for approximately four months. (hairscientists.org)
- catagen is a short resting phase until telogen, when the hair falls out. (antiaging-systems.com)
Regulates1
- The dermal papilla regulates the growth of hair, which in humans occurs in unsynchronized cycles, with each hair entering a phase of the cycle at a different time. (antiaging-systems.com)
Dormant1
- A recent study has identified the molecular pathway that, when activated, prompts hair growth from dormant hair follicles and, when blocked, prevents the growth of unwanted hair. (medicaldaily.com)
Transplants1
- FUE hair transplants are perfect for those who have thinning hair or a receding hairline, which they wish to build up. (hshairclinic.co.uk)
Structures1
- There are many structures that make up the hair follicle. (wikipedia.org)
Tissue4
- Hair regenerative medicine must involve practical procedures, such as cryopreservation of tissue grafts. (researchgate.net)
- Hair follicle germs (HFGs), identified during in vivo development, are considered effective tissue grafts for hair regenerative. (researchgate.net)
- In order to reduce morbidity associated with STSG harvesting, researchers have developed autologous dermo-epidermal substitutes (DESs) using cell culture, tissue engineering, and, more recently, bioprinting approaches. (frontiersin.org)
- This study provides interesting new insights into the specific cellular fate changes and tissue dysfunction that can occur following a high-fat diet or genetically induced obesity and may open the door for future prevention and treatment of hair thinning as well as for understanding of obesity-related diseases. (prohealth.com)
Outermost layer1
- The internal root sheath is composed of three layers, Henle's layer, Huxley's layer, and an internal cuticle that is continuous with the outermost layer of the hair fiber. (wikipedia.org)
Melanocyte1
- Finally, the convergence theory states that a combination of several pathways is necessary for the development of vitiligo, such as genetic background, susceptibility to environmental changes, altered epidermal microenvironment, an intrinsic melanocyte defect and an autoimmune response ( 13 , 14 ). (spandidos-publications.com)
Tissues1
- The epidermal growth factor receptor (EGFR) is expressed in epithelial tissues as well as hair follicles. (medscape.com)
Receptors2
- Hair follicle receptors sense the position of the hair. (wikipedia.org)
- There are also combination therapies that affect multiple receptors such as lapatinib (approved for human epidermal growth factor receptor 2-positive [HER2+] breast cancer) and afatinib (approved for non-small cell lung cancer), which inhibit both the EGFR and HER2 receptors, and vandetanib (approved for advanced medullary thyroid cancer), which inhibits EGFR, vascular endothelial growth factor (VEGFR), and rearranged during transfection (RET) activities. (medscape.com)
Barrier1
- epidermal barrier pulmonary immune diseases. (cdc.gov)
Follicular2
- The individual follicular bumps are often caused by a hair that is unable to reach the surface and becomes trapped beneath the keratin debris. (medscape.com)
- A follicular unit extraction (FUE) is a type of hair transplant offered at the Harley Street Hair Clinic . (hshairclinic.co.uk)
Inflammatory reaction1
- It is generally considered to be an inflammatory reaction to components of the hair follicle, particularly the micro-organisms. (e-ijd.org)
Genetics1
- Some families who have genetics that cause hair to grow quickly and some with genetics that cause hair to grow slowly. (nmhairreplacementstudio.com)
Thickness1
- This varying thickness primarily represents a difference in dermal thickness, as epidermal thickness is rather constant throughout life and from one anatomic location to another. (medscape.com)
Irritation1
- However, for irritation or cosmetic reasons, laser therapy can be used to remove hair and lighten the lesions. (contemporarypediatrics.com)
Growth patterns2
- Another unanswered issue is how long the hair follicles will grow and whether or not they exhibit the cyclical hair follicle growth patterns of a typical human hair follicle. (bernsteinmedical.com)
- The Hair and its growth patterns are genetically determined in both males and females. (hairscientists.org)
Induction1
- One of the challenges faced in this approach is the quantitative expansion of HFSCs while maintaining their hair induction capacity. (researchgate.net)
Grows3
- No hair therefore grows continuously. (hairscientists.org)
- There are a number of factors that influence how quickly your hair grows. (nmhairreplacementstudio.com)
- Have you been wondering how your hair grows? (nmhairreplacementstudio.com)
Characteristics3
- There are ethnic differences in several different hair characteristics. (wikipedia.org)
- Keratinocytic epidermal nevi are also known as linear epidermal nevi or verrucous epidermal nevi, based on characteristics of their appearance. (medlineplus.gov)
- Histological characteristics of the lesion of calcified epidermal cyst on the neck. (lww.com)
Abnormalities2
- There are many human diseases in which abnormalities in hair appearance, texture or growth are early signs of local disease of the hair follicle or systemic illness. (wikipedia.org)
- Some affected individuals have only an epidermal nevus and no other abnormalities. (medlineplus.gov)