• that are currently circulating in wild birds and poultry in much of the world are genetically different from earlier versions of the virus and emerged to become the predominant subtype of HPAI H5 in the fall of 2021. (cdc.gov)
  • Hooded vultures could potentially be vectors or sentinels of influenza subtype H5N1, as are cats and swans elsewhere. (cdc.gov)
  • On April 3, influenza A (subtype H5N1) was first confirmed in Burkina Faso. (cdc.gov)
  • The emergence and unfold of extremely pathogenic avian influenza (HPAI) A virus subtype H5N1 in Asia, Europe and Africa has had an enormously socioeconomic influence and presents an vital risk to human well being due to its environment friendly animal-to-human transmission. (flugenome.org)
  • Highly pathogenic avian influenza (HPAI) subtype H5N1 virus infections are constantly monitored worldwide because of their devastating effects on poultry. (usda.gov)
  • Unusually, in the spring of 2022, the HPAI virus (subtype H5N1) spread into our globally important colonies of nesting seabirds. (bto.org)
  • A sample from each location has tested positive for the highly pathogenic avian influenza (HPAI), subtype H5N1. (gov.mb.ca)
  • Influenza virus was isolated from lung, liver, kidney, and urine specimens, and the viral subtype was determined to be H5N1 by reverse transcription (RT)-PCR ( 6 ). (flu.org.cn)
  • The subtype behind the 2009 'swine flu' pandemic is H1N1, which has the same version of neuraminidase as H5N1, but a different version of hemagglutinin. (scientificamerican.com)
  • In October 2020, a new lineage of a clade 2.3.4.4b HPAI virus of the H5 subtype emerged in Europe, resulting in the largest global outbreak of HPAI to date, with unprecedented mortality in wild birds and poultry. (bvsalud.org)
  • The 1997 bird outbreak was controlled, but the H5N1 bird flu viruses were not eradicated in birds and re-surfaced in 2003 to spread widely in birds throughout Asia, and later in Africa, Europe, and the Middle East, causing poultry outbreaks and sporadic human infections. (cdc.gov)
  • On February 7, 2006, the first African outbreak of highly pathogenic avian influenza (HPAI) (H5N1) virus was reported from a farm in Kaduna State, northern Nigeria. (cdc.gov)
  • It is not known until February that it is an H5N1 outbreak. (wikipedia.org)
  • Learn more about the current worldwide outbreak of the HPAI H5N1 Avian Flu. (unmc.edu)
  • Over a 3-week period in late June/early July 2023, Poland experienced an outbreak caused by highly pathogenic avian influenza (HPAI) A(H5N1) virus in cats. (eurosurveillance.org)
  • Talks described the current outbreak of highly pathogenic avian influenza (HPAI - H5N2) epidemic in the Oudtshoorn area and the vigorous systematic response by the Animal Health Division of the Dept of Agriculture, the ongoing HPAI - H5N1 epidemic in Asia and Eastern Mediterranean region and H5N1 in humans and other flu viruses of this season. (sun.ac.za)
  • The last HPAI outbreak in Vet Nam was reported in August this year. (thepoultrysite.com)
  • This discovery follows an ongoing HPAI outbreak affecting seabirds on Rat and Marrowstone Islands in Washington since mid-summer. (thewhaletrail.org)
  • An outbreak of H5N1 avian influenza has been reported by Romanian veterinary officials in backyard poultry at a town in the Danube delta. (poultryworld.net)
  • In Saudi Arabia, officials reported that the country's latest H5N1 outbreak occurred at an egg production facility south of Riyadh, where all 216,000 birds will be culled. (poultryworld.net)
  • This is confirmed by the ministry to be the 14th H5N1 outbreak in the country. (poultryworld.net)
  • We report a fatal H5N1 infection in a dog following ingestion of an H5N1-infected duck during an outbreak in Thailand in 2004. (flu.org.cn)
  • There has been ongoing 'highly pathogenic avian influenza' (HPAI) or 'bird flu' outbreak in South Africa, of the strains HPAI H5 and H7, over the last few months. (sainthelena.gov.sh)
  • The ongoing outbreak of highly pathogenic avian influenza (HPAI) H5N1 in South Africa, which began in April 2021, has led to the culling of nearly 3 million birds, primarily layers. (usda.gov)
  • In response to the global outbreak in birds of highly pathogenic avian influenza (HPAI)​ A(H5N1), the Centers for Disease Control and Prevention (CDC) and the California Department of Public Health (CPDH) are encouraging continued testing for influenza this summer among persons with severe respiratory illness or who are exposed to poultry or swine. (ca.gov)
  • On February 9, 2022, USDA APHIS confirmed the first outbreak of HPAI A(H5N1) virus in a commercial turkey flock in Indiana [2]. (cdc.gov)
  • Evaluating the impact of environmental temperature on global highly pathogenic avian influenza (HPAI) H5N1 outbreaks in domestic poultry. (flugenome.org)
  • The outcomes confirmed that greater environmental temperature was a major threat issue for earlier incidence of HPAI H5N1 outbreaks in home poultry, particularly for a temperature of 25 °C. Its influence various with epidemic waves (EWs), and the magnitude of the influence tended to extend over EWs. (flugenome.org)
  • With the on-going European outbreaks of HPAI there is a risk of moving these viruses to North America as well. (usgs.gov)
  • VIET NAM - Three new outbreaks of highly pathogenic avian influenza (HPAI) have been reported in two northern provinces. (thepoultrysite.com)
  • The report describes three new outbreaks of HPAI, all starting on 18 November and in village flocks. (thepoultrysite.com)
  • Previous outbreaks of HPAI have tended to hit wintering waterfowl, subsiding as wintering flocks disperse. (bto.org)
  • In 2003, outbreaks of the highly pathogenic avian influenza (HPAI) H5N1 virus had a major negative impact on the global poultry industry. (usda.gov)
  • In 2006, the world poultry industry was again under pressure due to HPAI H5N1 outbreaks, this time in Europe. (usda.gov)
  • With new reports of H5N1 virus continuing across Asia, Europe, and Africa, this finding highlights the need for monitoring of domestic animals during outbreaks. (flu.org.cn)
  • Since then, APHIS has identified 247 HPAI A(H5N1) outbreaks among commercial poultry or backyard bird flocks in 29 states involving more than 35 million birds. (cdc.gov)
  • Ancestors of HPAI A(H5N1) viruses first emerged in southern China and led to large poultry outbreaks in Hong Kong in 1997, which resulted in 18 human infections. (cdc.gov)
  • Outbreaks of low and high pathogenic avian influenza (LPAI, HPAI) H5N2 in chickens have occurred in Taiwan since 2003 and 2012, respectively. (biomedcentral.com)
  • The two-stage survey (before and after HPAI H5N2 outbreaks) was conducted from 2007 to 2012, including: (1) 430 LPMWs and 418 CRs at LPMs from different geographical areas of Taiwan after the government announced outbreaks of LPAI H5N2 during 2007-2009, and (2) 73 LPMWs and 152 CRs at two LPMs in central Taiwan after the HPAI H5N2 outbreaks in 2012. (biomedcentral.com)
  • Before HPAI-H5N2 outbreaks, higher educated respondents demonstrated greater risk awareness and concerns regarding AI. (biomedcentral.com)
  • In poultry and wild birds, A(H5N1) and A(H5N6) subtypes were the most widely distributed, with outbreaks reported from 10 and eight countries and areas, respectively. (who.int)
  • As of September 2017, outbreaks associated with A(H5N1) viruses in domestic poultry and wild birds have occurred in more than 60 countries, and sporadic human infections with A(H5N1) viruses have been reported in 16 countries. (who.int)
  • We genetically analyzed influenza A (H5N1) viruses from Burkina Faso poultry and the first gene sequences obtained from African wild birds, hooded vultures ( Necrosyrtes monachus ). (cdc.gov)
  • The swabs of all birds were positive for HPAI (H5N1) virus, as evidenced by generic influenza A M-gene reverse transcription-PCR ( 1 ) and specific H5 PCR, as recommended by the European Union ( http://eur-lex.europa.eu/LexUriServ/site/en/oj/2006/l_237/l_23720060831en00010027.pdf , 04/08/2006). (cdc.gov)
  • According to reliable data and information from Gov.co.uk , Birds infected with the most serious strain of bird flu, called highly pathogenic avian influenza (HPAI), usually show some (or all) of the following signs. (oxfordshirewildliferescue.com)
  • The global spread of (highly pathogenic) H5N1 in birds is considered a significant pandemic threat. (wikipedia.org)
  • In addition, the spread of highly pathogenic H5N1 to wild birds, birds in zoos and even sometimes to mammals (example: pet cats) raises many unanswered questions concerning best practices for threat mitigation, trying to balance reducing risks of human and nonhuman deaths from the current nonpandemic strain with reducing possible pandemic deaths by limiting its chances of mutating into a pandemic strain. (wikipedia.org)
  • January 29, 2006 H5N1 is found in dead birds in northern Cyprus. (wikipedia.org)
  • The info clearly demonstrated the motion of H5N1 strains between Asian nations included on this research on account of migration of untamed birds and/or unlawful motion of poultry throughout borders. (flugenome.org)
  • As well as, H5N1 was transmitted to naïve management birds that had been positioned amongst each teams leading to dying by 5 days postcontact. (flugenome.org)
  • In distinction, Canada Geese that had been pre-exposed to H1N1 had been protected in opposition to a deadly H5N1 problem, shed minimal quantities of the virus into the atmosphere, and didn't transmit the an infection to naïve contact birds. (flugenome.org)
  • This Asian strain of H5N1 has been transmitted from birds to humans, most of whom had extensive, direct contact with infected birds. (webwire.com)
  • Between December 15, 2014, and May 29, 2015, the US Department of Agriculture (USDA) confirmed more than 200 findings of birds infected with highly-pathogenic avian influenza (HPAI) A (H5N2), (H5N8), and (H5N1) [1] viruses. (cdc.gov)
  • While these recently-identified HPAI H5 viruses are not known to have caused disease in humans, their appearance in North American birds may increase the likelihood of human infection in the United States. (cdc.gov)
  • For more information on the origin of the recently-identified HPAI H5 viruses in the United States, their clinical presentation in birds, and their suspected clinical presentation in humans, please see https://www.cdc.gov/flu/avianflu/hpai/hpai-background-clinical-illness.htm . (cdc.gov)
  • People should avoid unprotected exposure to sick or dead birds, bird feces, litter, or materials contaminated with suspected or confirmed HPAI H5 viruses. (cdc.gov)
  • On the other hand, highly pathogenic avian influenza (HPAI) strains frequently fatal to birds and easily transmissible between susceptible species. (usgs.gov)
  • In May of 2005 HPAI H5N1 was found in long range migratory birds at Qinghai Lake. (recombinomics.com)
  • The five sequences reported above (only 5 of the 47 H5's were from Manitoba) do little to address the question of HPAI H5 in the positive birds. (recombinomics.com)
  • Thus, finding LPAI in some birds does not preclude HPAI from the same birds or other H5 positive birds. (recombinomics.com)
  • HPAI H5N1 in migratory birds has been well characterized via full sequences from Qinghai Lake , Novosibirsk , and Mongolia . (recombinomics.com)
  • Like HPAI H5N1 in domestic birds in Asia, all wild bird isolates have a multi-basic HA cleavage site containing the sequence RRRKKR as well as an N1 with a 20 amino acid deletion. (recombinomics.com)
  • Instead Canada merely proved that two H5 positive birds contained LPAI H5N1, which doesn't address the presence or absence of H5N1 HPAI in any of the H5 positive birds, including those with LPAI H5N1. (recombinomics.com)
  • Highly pathogenic avian influenza (HPAI) A(H5N1) is a strain of the avian influenza virus that primarily affects birds, particularly poultry. (news-medical.net)
  • As of April 26, 2022, about 33 million farmed birds have contracted the H5N1 bird flu virus, while almost 800 wild birds have been infected, as well. (greenmatters.com)
  • Cases of HPAI H5N1 have been confirmed in a number of Canadian provinces and the United States including jurisdictions immediately south of Manitoba in North Dakota and Minnesota along the route for spring migratory birds returning to Manitoba. (gov.mb.ca)
  • This means there is a high probability of contact with wild birds that may be contaminated with the HPAI virus. (gov.mb.ca)
  • Influenza A H5N1 has killed millions of birds and raises serious public health concern because of its potential to spread to humans and cause a global pandemic. (biomedcentral.com)
  • Since most infected animals either recover - or die unnoticed in the wilderness - we don't really have a good handle on how many birds and mammals have been infected, or killed, by HPAI H5Nx avian flu since it arrived in North America nearly two years ago. (flutrackers.com)
  • We evaluate the dispersive potential of HPAI H5N1 viruses by wildfowl through an analysis of the movement range and movement rate of birds monitored by satellite telemetry in relation to the apparent asymptomatic infection duration (AID) measured in experimental studies. (britishecologicalsociety.org)
  • We analysed the first large-scale data set of wildfowl movements, including 228 birds from 19 species monitored by satellite telemetry in 2006-2009, over HPAI H5N1 affected regions of Asia, Europe and Africa. (britishecologicalsociety.org)
  • Our results provide a detailed quantitative assessment of the dispersive potential of HPAI H5N1 virus by selected migratory birds. (britishecologicalsociety.org)
  • Starting in January, the U.S. Department of Agriculture's (USDA) Animal and Plant Health Inspection Service (APHIS) detected highly pathogenic avian influenza (HPAI) A(H5N1) virus in wild birds in the United States followed by multiple detections in U.S. commercial poultry and backyard bird flocks [1,2]. (cdc.gov)
  • During January 13, 2022, through April 27, 2022, USDA APHIS reported more than 899 detections of wild birds infected with HPAI A(H5N1) virus in 33 states [1]. (cdc.gov)
  • The virus was identi ed as having a clade 2.3.4.4b HA and was determined to be the same genotype that has been detected in the majority of wild birds in South America, indicating no evidence for genetic reassortment compared to A(H5N1) viruses predominating in birds in South America. (cdc.gov)
  • The virus was 99% identical to many viruses identi ed in A(H5N1) virus-infected wild birds in Chile. (cdc.gov)
  • The virus appears to have become enzootic in birds, continuously yielding novel HPAI virus variants. (bvsalud.org)
  • 10 of these were new highly pathogenic avian influenza ( HPAI ) virus subtypes identified in animals, including birds (almost double the number of subtypes identified during the previous eight years). (cdc.gov)
  • While the recent detections of H5N1 bird flu in U.S. poultry and wild birds are thought to pose a low risk to the health of the general public at this time, human infections are possible. (cdc.gov)
  • While only one human case of H5N1 has been found in a person in the United States, CDC continues to help monitor for additional infections among people with contact with infected birds. (cdc.gov)
  • To date, more than 6,500 people in the United States who have had exposure to birds/poultry infected with H5N1 have been or are being monitored for symptoms. (cdc.gov)
  • January 30, 2006 According to WHO: The Ministry of Health in Iraq has confirmed the country's first case of human infection with the H5N1 avian influenza virus. (wikipedia.org)
  • To develop on this and higher perceive how pre-exposure to heterosubtypic low-pathogenic avian influenza (LPAI) viruses may affect the result of H5N1 HPAI an infection, we pre-exposed naïve juvenile Canada Geese to completely different North American wild-bird-origin LPAI viruses. (flugenome.org)
  • In a recent study published in the CDC's Emerging Infectious Diseases journal, researchers characterized the pathophysiology of infection by the highly pathogenic avian influenza (HPAI) A (H5N1) viral organism belonging to the Eurasian lineage and 2.3.4.4b clade in non-domesticated terrestrial animals across the United States (US) between 1 April and 21 July 2022. (news-medical.net)
  • The scale of HPAI H5N1 virus infection in cats in Poland is worrying. (eurosurveillance.org)
  • Additionally, differences were also observed in clinical disease after infection with a H5N1 HPAI virus, and the ducks innate immune responses also differed. (usda.gov)
  • Clinicians should consider the possibility of HPAI H5 virus infection in persons showing signs or symptoms of respiratory illness who have relevant exposure history. (cdc.gov)
  • State health departments are encouraged to investigate potential human cases of HPAI H5 virus infection as described below and should notify CDC within 24 hours of identifying a case under investigation. (cdc.gov)
  • Here, we report a case of HPAI H5N1 infection in a domestic dog following ingestion of the carcass of an infected duck. (greenmatters.com)
  • Small flocks are considered at high risk for HPAI infection as they often have access to outdoor pens or free range. (gov.mb.ca)
  • As of January 2012, HPAI H5N1 virus caused 577 laboratory-confirmed human cases of infection, of which 340 were fatal. (flutrackers.com)
  • Our results indicate that individual migratory wildfowl have the potential to disperse HPAI H5N1 over extensive distances, being able to perform movements of up to 2900 km within timeframes compatible with the duration of asymptomatic infection. (britishecologicalsociety.org)
  • However, the likelihood of such virus dispersal over long distances by individual wildfowl is low: we estimate that for an individual migratory bird there are, on average, only 5-15 days per year when infection could result in the dispersal of HPAI H5N1 virus over 500 km. (britishecologicalsociety.org)
  • As of October 3, 2016, at least 856 cases of human infection with avian influenza A (H5N1) virus in 16 countries had been reported to the World Health Organization, among which 452 had ended in death, for an apparent case fatality rate of 52.8% ( WHO, 2016 ). (frontiersin.org)
  • Regardless of novel LPAI or HPAI virus reassortants that pose public health risks, prompt and clear risk communication focusing on both correct information about AIVs and the most appropriate preventive measures are important for effective prevention of human infection. (biomedcentral.com)
  • 2023, provides a summary of the case and the genomic analysis of the virus from the rst H5N1 infection reported in a human in Chile. (cdc.gov)
  • On March 29, 2023, Chile reported its rst human infection with HPAI A(H5N1) virus. (cdc.gov)
  • Since the first confirmed human infection with avian influenza A(H5N1) virus was reported in Hong Kong SAR (China) in 1997, sporadic zoonotic avian influenza viruses causing human illness have been identified globally with the World Health Organization (WHO) Western Pacific Region as a hotspot. (who.int)
  • The pandemic potential of avian influenza viruses gained larger recognition in 1997 when the first known human infection with avian influenza A(H5N1) virus was reported in Hong Kong SAR (China). (who.int)
  • Phylogenetic tree for the hemagglutinin (HA) gene of African influenza A (H5N1) strains. (cdc.gov)
  • The hemagglutinin (HA) sequences of influenza A (H5N1) viruses from Burkina Faso clustered with recent western Asian, Russian, European, and African strains and are clearly distinct from southeastern Asian lineages (data not shown). (cdc.gov)
  • Phylogenetic comparison of the HA1 genes from Burkina Faso with all African influenza A (H5N1) HA sequences available from GenBank showed that the Burkina Faso strains cluster together and with A/chicken/Ivory Coast/1787/2006 ( Figure 1 ). (cdc.gov)
  • Nevertheless, there are four strains that have caused concern in recent years: H5N1 (since 1997), H7N9 (since 2013), H5N6 (since 2014), and H5N8 (since 2016). (oxfordshirewildliferescue.com)
  • Although H5N1, H7N9, and H5N6 strains do not easily spread from human to human, several people have been infected worldwide, resulting in numerous fatalities. (oxfordshirewildliferescue.com)
  • While prior H5N1 strains have been known, they were significantly different from the 2006 strain of H5N1 on a genetic level, making the global spread of this new strain unprecedented. (wikipedia.org)
  • HPAI, or high path avian influenza, is fatal and more easily transmissible than low path avian influenza strains that have been common in the U.S. since the early 1900s. (webwire.com)
  • Avian influenza is a viral disease caused by various strains of avian influenza viruses that can be classified as low pathogenic avian influenza (LPAI) or highly pathogenic avian influenza (HPAI). (usgs.gov)
  • Canadian scientists who have studied big chunks of the genetic code of the two proteins on the surface of the Manitoba H5N1 viruses have confirmed these viruses are from the family of North American H5N1 viruses, not the strains circulating in Southeast Asia. (recombinomics.com)
  • We analyzed 226 HA and 92 NA sequences with an emphasis on the H5N1 2.2.1.1 strains in Egypt using a Bayesian discrete phylogeography approach. (biomedcentral.com)
  • Research describing two mutant strains of H5N1 avian influenza that spread between mammals is likely to be published in its entirety. (scientificamerican.com)
  • Two teams of scientists, led by Ron Fouchier of Erasmus Medical Center in Rotterdam, the Netherlands, and Yoshihiro Kawaoka of the University of Wisconsin-Madison, have created mutant strains of H5N1 avian influenza. (scientificamerican.com)
  • Wild H5N1 viruses cannot latch on tothe cells in a person's nose and throat, but the mutant strains created by Fouchier and Kawaoka can spread between ferrets, which are viewed as a good animal model of flu transmission between humans. (scientificamerican.com)
  • Only some strains are classified as 'highly pathogenic' or HPAI for short. (sainthelena.gov.sh)
  • The only people who use its full name-H5N1-HPAI-clade 2.3.4.4b-are typically scientists who study emerging viruses, such as Nichola Hill at the University of Massachusetts Boston. (motherjones.com)
  • The team built phylogenetic interpretation trees and single-nucleotide polymorphism (SNP) tables using a reference including six segments from the H5N1 clade 2.3.4.4b virus and two from non-domesticated avian viruses from the northern regions of America. (news-medical.net)
  • The identified viruses belong to clade 2.3.4.4b, genotype CH (H5N1 A/Eurasian wigeon/Netherlands/3/2022-like). (eurosurveillance.org)
  • Genetic analysis of highly pathogenic avian influenza (H5N1) viruses from poultry and hooded vultures in Burkina Faso shows that these viruses belong to 1 of 3 sublineages initially found in Nigeria and later in other African countries. (cdc.gov)
  • Only countries where highly pathogenic avian influenza A (H5N1) sequences from avian species are available are named. (cdc.gov)
  • Riverside County Chief Veterinarian Dr. Sara Strongin received confirmation of the Eurasian highly pathogenic avian influenza (or HPAI H5N1) late Tuesday afternoon. (rivco.org)
  • The 2006 strain of H5N1 is a fast-mutating, highly pathogenic avian influenza virus (HPAI) found in multiple bird species. (wikipedia.org)
  • Genetic range and phylogenetic evaluation of extremely pathogenic avian influenza ( HPAI ) H5N1 viruses circulating in Bangladesh from 2007-2011. (flugenome.org)
  • Extremely pathogenic avian influenza (HPAI) H5N1 virus has been endemic in Bangladesh since its first isolation in February 2007. (flugenome.org)
  • In earlier research we examined the function of Canada Geese (Branta canadensis) within the epidemiology of Eurasian extremely pathogenic avian influenza (HPAI) H5N1. (flugenome.org)
  • Enhanced infectivity of H5N1 extremely pathogenic avian influenza ( HPAI ) virus in pig ex vivo respiratory tract organ cultures following adaptation by in vitro passage. (flugenome.org)
  • WOAH reported highly pathogenic avian influenza (HPAI) H5N1 in Mai Po Nature Reserve during routine surveillance. (emergence-msd-animal-health.com)
  • Vaccination of domestic ducks against highly pathogenic avian influenza (HPAI) H5N1 has been done in Asia with mixed results. (usda.gov)
  • In the present study, researchers presented a series of cases to highlight the pathophysiology of spontaneous HPAI H5N1 infections among terrestrial wild animals in the US, which coincided with elevated levels of highly pathogenic avian influenza viruses in circulation among non-domesticated avian species during summer and spring of 2022. (news-medical.net)
  • Highly Pathogenic Avian Influenza (HPAI) H5N1 virus is a threat to animal and public health worldwide. (ias.ac.in)
  • Domestic ducks are key intermediates in the transmission of H5N1 highly pathogenic avian influenza (HPAI) viruses, and therefore are included in vaccination programs to control H5N1 HPAI. (usda.gov)
  • The USGS National Wildlife Health Center (NWHC) in collaboration with multiple partners conducts research into the ecology of avian influenza virus and surveillance for highly pathogenic avian influenza (HPAI) viruses leading to several significant findings towards early detection and response to HPAI. (usgs.gov)
  • New Cases in Scotland Highly pathogenic avian influenza (HPAI) H5N1 was confirmed at a second premises in Lower Barvas, Isle of Lewis on 15 September 2023. (rpra.org)
  • It is referred to as 'highly pathogenic' avian influenza, or HPAI. (bto.org)
  • Three adult harbor seals in Puget Sound, Washington have tested positive for the Highly Pathogenic Avian Influenza H5N1 strain. (thewhaletrail.org)
  • Highly pathogenic avian influenza (HPAI) H5N1 has spread across Asia, Europe, and Africa. (greenmatters.com)
  • Most cases tested in Poland (29 of 47) were positive for highly pathogenic avian influenza (HPAI) A (H5N1) virus. (flu.org.cn)
  • In the United Kingdom, there have been 182 confirmed cases of highly pathogenic avian influenza (HPAI) H5N1 since 1 October 2022. (thestar.co.uk)
  • Gross and microscopic lesions from dog infected with highly pathogenic avian influenza (HPAI) H5N1. (flu.org.cn)
  • One particular strain of H5N1, called highly pathogenic avian influenza (HPAI), is responsible for the 'bird flu' scares. (scientificamerican.com)
  • Since its first detection in 1997, highly pathogenic avian influenza (HPAI) H5N1 virus has devastated the poultry industry of numerous countries of the Eastern Hemisphere. (flutrackers.com)
  • There is a high risk that Highly Pathogenic Avian Influenza (HPAI H5N1) will arrive in the Southern Ocean during the 2023/24 austral summer. (usap.gov)
  • Potential spread of highly pathogenic avian influenza H5N1 by wildfowl: dispersal ranges and rates determined from large-scale satellite telemetry. (britishecologicalsociety.org)
  • In recent years, wildfowl have been suspected of contributing to the rapid geographic spread of the highly pathogenic avian influenza (HPAI) H5N1 virus. (britishecologicalsociety.org)
  • The novel Eurasian highly pathogenic avian influenza HPAI A (H5N8) virus spread rapidly and globally during 2014, substantially affecting poultry populations. (cdc.gov)
  • Since 2003, multiple highly pathogenic avian influenza A (HPAI) H5 subtypes, including H5N1, H5N2, H5N6, and H5N8, have generated severe epidemics and thus not only tremendous economic losses in the domestic poultry industry, but also serious threats to human health worldwide ( Jhung and Nelson, 2015 ). (frontiersin.org)
  • Since the first occurrence of HPAI H5N1 human cases in Hong Kong in 1997, the public health threat of high pathogenic avian influenza (HPAI) has been a major global issue [ 1 ]. (biomedcentral.com)
  • To provide guiding principles and minimum requirements for surveillance and diagnosis of H5N1 highly pathogenic avian influenza (HPAI) that can be applied by countries and regional networks. (bvs.br)
  • On 17 April 2023, the US CDC provided information on the genomic analysis of the samples from the first human infected with avian influenza A(H5N1) in Chile. (poultrymed.com)
  • This is the second human case of A(H5N1) ever reported in South America, which includes a January 2023 case reported by Ecuador (1 ). (cdc.gov)
  • Since 2003, more than 20 countries have reported more than 860 human infections with H5N1 bird flu viruses to WHO. (cdc.gov)
  • General, the info indicate genetic range amongst circulating viruses and a number of introductions of H5N1 viruses with an elevated threat of human infections in Bangladesh, and institution of H5N1 virus in wild and home fowl populations, which calls for lively surveillance. (flugenome.org)
  • HPAI H5N1 viruses that have caused human infections with high mortality in other countries). (cdc.gov)
  • The dog´s owner stated that the dog had eaten duck carcasses from an area with reported HPAI H5N1 infections in ducks. (flu.org.cn)
  • Once again, severe neurological symptoms were noted, which have been increasingly linked to HPAI H5 infections (see Cell: The Neuropathogenesis of HPAI H5Nx Viruses in Mammalian Species Including Humans ). (flutrackers.com)
  • We report and describe infections by HPAI H5N1 virus in 2 black bears (Ursus americanus) found in Quebec, Canada, during the summer of 2022. (flutrackers.com)
  • However, the true mortality rate will be lower because there are probably some milder, unrecorded infections of H5N1. (scientificamerican.com)
  • The increasing number of fatal cases due to H5N1 infections prompted the government of Hong Kong to initiate policies forbidding the slaughtering of live chickens or other poultry in wet markets [ 13 ]. (biomedcentral.com)
  • Between November 2003 and September 2017, WHO received reports of 1838 human infections with avian influenza viruses A(H5N1), A(H5N6), A(H6N1), A(H7N9), A(H9N2) and A(H10N8) in the Western Pacific Region. (who.int)
  • Most of the infections were with A(H7N9) ( n = 1562, 85%) and A(H5N1) ( n = 238, 13%) viruses, and most ( n = 1583, 86%) were reported from December through April. (who.int)
  • 6 Thereafter, the number of countries reporting human infections with A(H5N1) virus increased, especially between 2003 and 2008. (who.int)
  • HPAI was identified in 67 non-domesticated animals across 10 US states between April and July 2022, including 50 red-colored foxes, six striped skunks, four raccoons, two bobcats, two Virginia opossums, one coyote, one fisher, and one gray fox. (news-medical.net)
  • On April 20, 2022, an adult in Colorado developed fatigue following exposure to presumptive H5N1 virus-infected poultry while participating in poultry depopulation activities during April 18-22, 2022. (cdc.gov)
  • There are two types of the virus: high pathogenicity (HPAI) and low pathogenicity (LPAI), which indicate how severe the disease can be if a bird gets infected. (oxfordshirewildliferescue.com)
  • Because of the size differences between HPAI and LPAI HA and NA genes, the two types of sequences can be easily distinguished one the basis of size. (recombinomics.com)
  • Fully understanding the different awareness, attitudes and protective behaviors adopted by workers in live-poultry markets (LPMWs) and local community residents (CRs) to face the challenges of LPAI and HPAI is very important to minimize viral adaptations to human populations. (biomedcentral.com)
  • In the first two months of 2006 H5N1 spread to Africa and Europe in wild bird populations possibly signaling the beginning of H5N1 being endemic in wild migratory bird populations on multiple continents for decades, permanently changing the way poultry are farmed. (wikipedia.org)
  • Avian influenza (H5N1) is rare in humans in developed countries. (medscape.com)
  • Until more is known about these newly-identified HPAI H5 viruses, public health recommendations are largely consistent with guidance for influenza viruses associated with severe disease in humans (e.g. (cdc.gov)
  • Avian influenza H5N1 virus is known to cross the species barrier and infect humans and felines. (flu.org.cn)
  • Sequencing and phylogenetic analysis of the hemaggluttinin (HA) and neuraminadase (NA) genes of the dog´s virus showed that they were similar to those of H5N1 viruses isolated from tigers, chickens, ducks, and humans infected in Thailand during the same time that the dog was infected ( Figure 2A and B ). In addition, analysis of 6 other genes from KU-08 showed similar results (data not shown). (flu.org.cn)
  • More practically, the research could allow public-health workers to monitor wild viruses for similar mutations that make H5N1 more dangerous to humans. (scientificamerican.com)
  • A resurgence of A(H5N1) occurred in humans and animals in November 2003. (who.int)
  • 7 In addition to A(H5N1), other novel zoonotic influenza viruses infecting humans have emerged, including A(H5N6), A(H7N9), A(H10N8), A(H6N1) and a novel A(H1N2) variant. (who.int)
  • Pre-exposing Canada Geese (Branta canadensis) to a low-pathogenic H1N1 avian influenza virus protects them in opposition to H5N1 HPAI virus problem. (flugenome.org)
  • In this study, we have designed three siRNAs (PB2-2235, PB2-479 and NP-865) targeting PB2 and NP genes of avian influenza virus and evaluated their potential, measured by hemagglutination (HA), plaque reduction and Real time RT-PCR assay, in inhibiting H5N1 virus (A/chicken/Navapur/7972/2006) replication in MDCK cells. (ias.ac.in)
  • Phylogenetic analysis of the hemagglutinin (A) and neuraminidase (B) gene sequences of the H5N1 influenza virus isolated from a dog´s lung. (flu.org.cn)
  • After the reported spread of HPAI H5N1 virus in Asia, a large, interagency avian influenza virus, or AIV, surveillance effort was implemented throughout the United States during April 2006 to March of 2011. (cdc.gov)
  • Unless otherwise indicated, "H5N1" in this article refers to the highly pathogenic 2006 strain of H5N1. (wikipedia.org)
  • Her brother, 14-year-old Mehmet Ali Kocyigit, had already died of the H5N1 strain of bird flu, officials said on Wednesday, confirming the first human death from the disease outside Mainland China and southeast Asia. (wikipedia.org)
  • The Asian strain of H5N1 has not been detected in the U.S. HPAI has been detected three times in the United States: in 1924, 1983 and 2004. (webwire.com)
  • Kawaoka and his team, whose work has been accepted by Nature, created a chimeric virus with the hemagglutinin protein from H5N1 and the genes from the 2009 pandemic strain of H1N1. (scientificamerican.com)
  • Sequencing could then be used to verify that larger HA inserts or smaller NA inserts contained sequences that matched the published sequences for HPAI H5N1. (recombinomics.com)
  • The FDA has approved a vaccine for H5N1 influenza. (medscape.com)
  • This information should be taken into account when implementing vaccine strategies for control of HPAI in different bird species. (usda.gov)
  • Phylogeography can highlight the drivers of H5N1 emergence and spread. (biomedcentral.com)
  • Following the emergence of avian influenza H5N1 and the fear of its pandemic potential, having an adequate preparedness plan became a priority as the World Health Organization (WHO) urged every country to develop and maintain an up-to-date national influenza preparedness plan, and provided guidance on plan content (5). (who.int)
  • Following the emergence of avian influenza H5N1 to the H1N1 pandemic was a learning experience on and the fear of its pandemic potential, having an adequate which capacity to face future events in the Region can preparedness plan became a priority as the World Health be built and strengthened. (who.int)
  • This marks the first incidence of HPAI in marine mammals on the West Coast. (thewhaletrail.org)
  • These results should be taken into account when developing effective vaccination programs for controlling HPAI in different species of ducks, since we demonstrated that not all duck species respond equally to avian influenza vaccination. (usda.gov)
  • In this study we compared the response to vaccination between two common domestic duck species, Pekin and Muscovy, which were vaccinated using one of three different schedules in order to obtain protection to H5N1 HPAI before one month of age. (usda.gov)
  • This information is important and should be taken into account when developing effective vaccination programs for controlling HPAI in different species of ducks. (usda.gov)
  • Monitoring work carried out by the Animal and Plant Health Agency (APHA) also confirmed HPAI in other species including raptors, wildfowl, waders, and gamebirds. (bto.org)
  • Together, Britain and Ireland support 25% of Europe's breeding seabirds, including more than 50% of the world population of species which have been severely impacted by HPAI, such as Great Skua and Gannet. (bto.org)
  • Avian influenza (HPAI) H5N1 was confirmed in commercial poultry on April 29 at premises near Cantley, Doncaster, according to the Department for Environment, Food & Rural Affairs. (thestar.co.uk)
  • The widespread detection of H5 raised the possibility of HPAI H5N1 migration into North America from Europe or Asia. (recombinomics.com)
  • Clear differences in response to vaccination were observed, with the Muscovy ducks presenting lower viral antibody titers induced by vaccination and higher number of sick and dead ducks after challenge with a H5N1 HPAI virus. (usda.gov)
  • For Egypt, future work should focus on using data about vaccination and live bird markets in phylogeography models to study their impact on H5N1 diffusion within the country. (biomedcentral.com)
  • HPAI is a "zoonotic disease" that has the potential to spread between animals and people and their pets. (thewhaletrail.org)
  • Ducks have been implicated in the dissemination and evolution of H5N1 HPAI viruses. (usda.gov)
  • Both cats and tigers were reported as becoming infected after eating poultry carcasses harboring HPAI. (greenmatters.com)
  • Many components contribute to the incidence and transmission of HPAI H5N1 virus, however the function of environmental temperature stays poorly understood. (flugenome.org)
  • In contrast to previous H5N1 viruses, which still circulate to a lesser extent in several countries, at this time, fewer than 10 cases with current H5N1 bird flu viruses have been reported globally. (cdc.gov)
  • Kawaoka notes that H5N1 viruses already circulate in nature, mutate constantly and could cause pandemics. (scientificamerican.com)
  • So far, H5N1 has failed to spark a pandemic because it cannot effectively spread between people. (scientificamerican.com)
  • The pandemic burden became recently more significant in the EMR with the sudden surge in human cases of H5N1 in Egypt. (who.int)
  • They are both from the same area as the prior three children that died from H5N1 bringing the total number of cases in Turkey to 5, with 2 of them fatal. (wikipedia.org)
  • Till date, the H5N1 virus has claimed 402 human lives, with a mortality rate of 58% and has caused the death or culling of millions of poultry since 2003. (ias.ac.in)
  • Since the original human cases of H5N1 originated in Asia [ 1 ], much of the attention concerning the virus has been in Asian countries. (biomedcentral.com)
  • Due significant in the EMR with the sudden surge in human to frequent mutations and reassortment in its genome, cases of H5N1 in Egypt. (who.int)
  • A 53% case fatality has been reported among human cases of A(H5N1), which has been associated with severe pneumonia. (who.int)
  • 1,8 The Western Pacific Region has reported more than one quarter (238/860) of global A(H5N1) cases and is the second most affected region. (who.int)
  • For California Department of Fish and Wildlife HPAI fact sheet, click here . (rivco.org)
  • HPAI A (H5N1) has spread over Europe and the US from October 2021 onward. (news-medical.net)
  • However, HPAI H5N1 viruses reappeared in 2003, spread across continents, and sickened 826 patients from 2003 to March 31, 2015 [ 5 ]. (biomedcentral.com)
  • HPAI H5N1 is the type currently affecting parts of Asia and Eastern Europe. (webwire.com)