• BEIJING, July 22 /PRNewswire-Asia/ -- Sinovac Biotech Ltd. (NYSE AMEX: SVA), a leading provider of vaccines in China, today announced that it has initiated dosing today in its clinical trial of various Panflu vaccine candidates for pandemic influenza A (H1N1). (sinovac.com)
  • Therefore, we are examining H1N1 vaccines that provide safety, efficacy, and high volume scalability and can perform for different levels of prevalence and pathogenicity. (sinovac.com)
  • Sinovac's commercialized vaccines include Healive® (hepatitis A), Bilive® (combined hepatitis A and B), Anflu® (influenza) and Panflu(TM) (H5N1). (sinovac.com)
  • These six countries and the occupied Palestine territory received pandemic influenza vaccines from WHO as donations to cover at least 10% of their total population. (who.int)
  • Now H1N1 is a component of the trivalent and quadrivalent influenza vaccines. (medscape.com)
  • Effectiveness of non-adjuvanted pandemic influenza A vaccines for preventing pandemic influenza acute respiratory illness visits in 4 U.S. communities. (blogspot.com)
  • When assessing the association between pandemic influenza vaccines and Guillain-Barré syndrome it is important to account for the effects of influenza-like illness/upper respiratory tract infection, seasonal influenza vaccination, and calendar time. (qxmd.com)
  • How effective are seasonal influenza vaccines in tropical communities? (medscape.com)
  • Current strategies to control swine influenza virus (SIV) in animals typically include one of several commercially available bivalent swine influenza virus vaccines. (medscape.com)
  • This particular H3N2 PB1 gene is known to have residues in the recent ancestral swine viruses of pandemic originated from an avian virus that entered humans in (H1N1) 2009 virus showed that 7 had already transitioned 1968. (cdc.gov)
  • There have been three influenza pandemics in the 20th century, initially observed in 1918, 1957, and 1968, respectively, referred to as the Spanish (H1N1), Asian (H2N2), and Hong Kong (H3N2) influenza [ 1 ]. (hindawi.com)
  • Alice: Co-circulation of pandemic 2009 H1N1, swine H3N2 and H1N2 influenza viruses in pigs in the state of Rio Grande do Sul. (embrapa.br)
  • Here, using crystallography and cryo-electron microscopy, we determine the structures of FluPol A from human influenza A/NT/60/1968 (H3N2) and avian influenza A/duck/Fujian/01/2002 (H5N1) viruses at a resolution of 3.0-4.3 Å, in the presence or absence of a cRNA or vRNA template. (nature.com)
  • Since avian-origin H3N2 canine influenza virus (CIV) was first identified in South Korea in 2008, the novel influenza virus has been reported in several countries in Asia. (biomedcentral.com)
  • Here we describe the viral dominance of 23 CIV reassortants between pH1N1 and canine H3N2 influenza viruses from a naturally co-infected dog. (biomedcentral.com)
  • These results indicate that the M gene of pandemic H1N1 and the HA gene of canine H3N2 are predominant in the reassortants. (biomedcentral.com)
  • Results indicated that infection with pandemic (H1N1) 2009 broadens cross-reactive immunity to other recent subtype H1 swine viruses. (cdc.gov)
  • Pandemic (H1N1) 2009 was able to spread globally because it was antigenically divergent from contemporary human seasonal subtype H1N1 influenza viruses ( 1 ). (cdc.gov)
  • In this study, we assessed the relationship between seroconversion to pandemic (H1N1) 2009 and cross-reactive antibody responses to other major subtype H1 swine viruses in humans. (cdc.gov)
  • Neutralizing antibody titers to subtype H1 swine influenza viruses of the classical swine, North American triple reassortant, and Eurasian avian-like swine lineages in baseline (prepandemic [pre]) and convalescent-phase (postpandemic [post]) serum. (cdc.gov)
  • Subtype H1 swine influenza viruses, representative of CS, Eurasian avian-like swine (EA), triple reassortant swine (TRIG), pandemic (H1N1) 2009 viruses, and selected reassortants between these lineages with diverse antigenic profiles, were selected from our surveillance of swine influenza viruses in China ( 3 ). (cdc.gov)
  • Heterosubtypic immunity is defined as immune-mediated (partial) protection against an influenza virus induced by an influenza virus of another subtype to which the host has not previously been exposed. (eur.nl)
  • This cross-protective effect has not yet been demonstrated to the newly emerging avian influenza A viruses of the H7N9 subtype. (eur.nl)
  • The same subtype, A(H1N1) has been circulating in human population since 1977. (elsevierpure.com)
  • The H1N1 virus that caused that pandemic is now a regular human flu virus and continues to circulate seasonally worldwide. (cdc.gov)
  • Pandemic (H1N1) 2009 virus consists of multiple re- gence of infl uenza A pandemic (H1N1) 2009 virus, which assorted virus genes from different origins. (cdc.gov)
  • H1N1) 2009 virus. (cdc.gov)
  • in pandemic (H1N1) 2009 virus, this residue changed 2009 virus descended directly from the classic swine in- into a human-like R. Signatures that separate swine viruses fl uenza A virus of North American lineage, which can be from human viruses were also present. (cdc.gov)
  • H1N1) 2009 virus have revealed important information is based on an entropy threshold computed from the amino for promoting medical diagnosis, drug-resistance monitor- acid composition at the well known PB2-627 position of ing, clinical and basic research, and vaccine development. (cdc.gov)
  • Nevertheless, analyzing adaptive mutation of the new pan- on 95 avian infl uenza genomes, as of early 2006), which demic (H1N1) 2009 virus is a priority so that researchers contains mostly glutamic acid in the native avian hosts of can evaluate the likelihood that viruses from other nonhu- the viruses. (cdc.gov)
  • The Emergency Committee said that the virus probably will continue to circulate for some years, taking on the behavior of a seasonal influenza virus. (uspharmacist.com)
  • i) The influenza (H1N1) virus responsible for the 1918-19 pandemic was closely related to foregoing H1N1 virus(es) that might have widely circulated earlier than 1918. (hindawi.com)
  • This project was initiated prior to the 2010 Winter Olympic Games, in anticipation that the convergence of pandemic influenza ("swine flu" virus), seasonal influenza and the games threatened to create a public health challenge in BC. (genomebc.ca)
  • To mitigate this threat, the BC Centre for Disease Control (BCCDC) was tasked with undertaking an accelerated pandemic vaccine initiative for the new H1N1 virus, much of which was funded by national and provincial agencies. (genomebc.ca)
  • To assess herd immunity to swine influenza viruses, we determined antibodies in 28 paired serum samples from participants in a prospective serologic cohort study in Hong Kong who had seroconverted to pandemic (H1N1) 2009 virus. (cdc.gov)
  • Because we now recognize that pandemics can arise from influenza subtypes endemic in humans, it is essential that subtypes H1 and H3 swine viruses be considered potential future pandemic candidates, together with other avian virus subtypes such as H2, H5, or H9. (cdc.gov)
  • Influenza virus subtypes H1 and H3 of diverse lineages are endemic in swine and are globally widespread. (cdc.gov)
  • We previously showed a lack of herd immunity in humans to some of these swine virus lineages in serum samples collected before the 2009 pandemic ( 3 ). (cdc.gov)
  • However, the spread of pandemic (H1N1) 2009 worldwide may generate cross-reactive herd immunity to some of these swine virus lineages, making them less likely candidates for future pandemics. (cdc.gov)
  • Twenty-eight paired serum samples from a prospective serologic cohort study in Hong Kong, in which participants seroconverted to the pandemic (H1N1) 2009 virus, were selected to represent persons of diverse ages (median 39.5 years, range 8-74 years). (cdc.gov)
  • Each pair of baseline and convalescent-phase serum samples was tested for antibodies by microneutralization tests using each swine influenza virus. (cdc.gov)
  • As expected, no serologic response occurred to seasonal influenza (H1N1) virus A/HK/400599/2008. (cdc.gov)
  • The trial, which is taking place in Germany, involves 130 healthy volunteers aged 18 to 60 years old, and has been designed to evaluate the tolerability and immunogenicity of GSK's split-virus pandemic (H1N1) adjuvanted vaccine in comparison with an unadjuvanted test study formulation. (gsk.com)
  • Here, we assessed the induction of protective immunity to these viruses by infection with A(H1N1)pdm09 virus in a newly developed guinea pig model. (eur.nl)
  • To this end, ten female 12-16 week old strain 2 guinea pigs were inoculated intratracheally with either A(H1N1)pdm09 influenza virus or PBS (unprimed controls) followed 4 weeks later with an A/H7N9 influenza virus challenge. (eur.nl)
  • Among a sample of participants of all ages collected during the year 2010, the antibody testing of stored sera specimens from NHANES 2009-2010 was conducted to determine population levels of pre-pandemic cross reactive antibody to the 2009 pandemic influenza A/H1N1 virus and related influenza viruses prior to the spread of the novel 2009 H1N1 virus. (cdc.gov)
  • Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. (cdc.gov)
  • Sensitivity and Specificity of Serologic Assays for Detection of Human Infection with 2009 Pandemic H1N1 Virus in U.S. Populations. (cdc.gov)
  • Acute encephalopathy has been associated with influenza A virus infection. (medscape.com)
  • But the virus that caused a pandemic in 2009 was A(H1N1) that was originated from swine influenza. (elsevierpure.com)
  • In March 2009, a novel swine-origin influenza A/H1N1 virus was identified. (scienceopen.com)
  • In late April 2009, a novel influenza virus emerged in humans--pandemic (HIN1) 2009--and spread rapidly across the world. (who.int)
  • By then, the transmission of influenza caused by this novel virus had slowed considerably across the globe. (who.int)
  • H1N1) 2009 virus infection, with approximately 18 500 reported deaths. (who.int)
  • In most countries of the Region, cases of pandemic (H1N1) virus infection were initially identified in urban centres following introduction of the virus through travellers coming from affected countries. (who.int)
  • All the countries in the Region were provided with PCR diagnostic kits for diagnosis of novel pandemic (H1N1) 2009 influenza virus. (who.int)
  • Potency of a vaccine prepared from A/swine/Hokkaido/2/1981 (H1N1) against A/Narita/1/2009 (H1N1) pandemic influenza virus strain by: Okamatsu Masatoshi, et al. (uitm.edu.my)
  • Influenza A virus (H1N1), which arose in 2009, constituted the fourth pandemic after the cases of 1918, 1957, and 1968. (benthamopen.com)
  • In the past 3 years, the 2009 pandemic influenza virus H1N1 (pH1N1) has led to many severe or fatal cases. (bvsalud.org)
  • Novel H1N1 (referred to as "swine flu" early on) is a new influenza virus causing illness in people. (spiritindia.com)
  • This virus is spreading from person-to-person, probably in much the same way that regular seasonal influenza viruses spread. (spiritindia.com)
  • There is some evidence to support the wearing of masks or respirators during illness to protect others, and public health emphasis on mask wearing during illness may help to reduce influenza virus transmission. (cambridge.org)
  • Further studies in controlled settings and studies of natural infections in healthcare and community settings are required to better define the effectiveness of face masks and respirators in preventing influenza virus transmission. (cambridge.org)
  • Pandemic influenza A (H1N1) virus emerged in Mexico in early 2009 and rapidly spread worldwide. (cambridge.org)
  • We conducted a systematic review [ Reference Moher 6 ] to investigate the evidence supporting the effectiveness of face masks in reducing influenza virus infection under controlled and natural conditions. (cambridge.org)
  • While in Northern hemisphere countries, the pandemic H1N1 virus (H1N1pdm) was introduced outside of the typical influenza season, Southern hemisphere countries experienced a single wave of transmission during their 2009 winter season. (ox.ac.uk)
  • These results confirm the transmissibility of the 2009 H1N1 pandemic virus was relatively low compared with past pandemics. (ox.ac.uk)
  • However, because there was early widespread circulation of the 2009 H1N1 virus, many persons in the United States became ill before vaccine was available. (blogspot.com)
  • Reverse zoonotic transmission of pandemic H1N1 (2009) influenza virus (pH1N1) has been observed in a broad range of animal species. (biomedcentral.com)
  • From 2010 to 2012 in South Korea, we collected 213 nasal swabs from sick dogs showing clinical respiratory signs and tested the presence of canine influenza virus (CIV). (biomedcentral.com)
  • What are the diagnostic practices for influenza and other respiratory virus in U.S. hospitals and laboratories? (medscape.com)
  • However, the swine influenza virus can be transmitted to humans via contact with infected pigs or environments contaminated with swine influenza viruses. (medscape.com)
  • Swine influenza virus. (medscape.com)
  • Once a human becomes infected, he or she can then spread the virus to other humans, presumably in the same way as seasonal influenza is spread (ie, via coughing or sneezing). (medscape.com)
  • La presencia de condiciones médicas pre-existentes se ha asociado con la mortalidad relacionada al virus de influenza A (H1N1). (bvsalud.org)
  • The presence of pre-existing medical conditions has been associated with mortality related to influenza A virus (H1N1). (bvsalud.org)
  • ABSTRACT A novel strain of influenza A virus H1N1 surfaced in Mexico in April 2009 and quickly spread across the globe, turning an epidemic into a pandemic. (who.int)
  • RÉSUMÉ Une nouvelle souche du virus de la grippe A H1N1 est apparue au Mexique en avril 2009 et s'est rapidement propagée au monde entier, transformant l'épidémie en pandémie. (who.int)
  • The purpose of this document is to provide a basis for advice to clinicians on the use of the currently available antivirals for patients presenting with illness due to influenza virus infection, as well their use for chemoprophylaxis. (bvsalud.org)
  • Influenza Vaccine The influenza virus vaccine helps protect against influenza. (msdmanuals.com)
  • Two types of influenza virus, type A and type B, regularly cause seasonal epidemics of influenza in the United States. (msdmanuals.com)
  • The strain of influenza virus causing outbreaks is always changing slightly, so that each year the influenza virus is a little different from the previous year's. (msdmanuals.com)
  • Influenza type A strains are named based on the specific versions of two proteins present on the surface of the virus. (msdmanuals.com)
  • Objective To determine whether any association exists between exposure to 2009 pandemic H1N1 (pH1N1) influenza vaccination during pregnancy and negative health outcomes in early childhood. (bmj.com)
  • Results Of 104 249 live births, 31 295 (30%) were exposed to pH1N1 influenza vaccination in utero. (bmj.com)
  • Antiviral therapy and vaccination are important strategies for controlling pandemic 2009 influenza A(H1N1) but efficacy depends on the timing of administration and is often limited by supply shortage. (flutrackers.com)
  • SINOVAC was the first company to be granted approval for its H1N1 influenza vaccine Panflu.1 ® , which has supplied the Chinese government's vaccination campaign and stockpiling program. (sinovac.com)
  • As a result of a programming error, the model used to estimate the impact of vaccination did not adequately adjust for the decreasing risk for disease as the pandemic progressed, and thus the impact of vaccination was overestimated. (blogspot.com)
  • CDC continues to work on developing and evaluating statistical models for estimating the impact of influenza vaccination in order to develop better programs and ways to monitor the impact of those programs. (blogspot.com)
  • After adjustment for influenza-like illness/upper respiratory tract infection and seasonal influenza vaccination, receipt of pandemic influenza vaccine was not associated with an increased risk of Guillain-Barré syndrome (adjusted odds ratio 1.0, 0.3 to 2.7). (qxmd.com)
  • School-located influenza vaccination programs have the potential to mass-vaccinate all enrolled children, but will parents give consent? (medscape.com)
  • To this end, the Regional Office conducted a series of training sessions to build country capacities for diagnosis and management of pandemic influenza, including the development of communication strategies. (who.int)
  • Researchers explored these questions this past spring in Texas, the second state to have confirmed person-to-person spread of pandemic H1N1 2009 flu. (cdc.gov)
  • The pattern of severity appears to be changing with the spread of pandemic (H1N1) 2009, which can be conceptualized in a step-wise manner based on observation of the current situation. (elsevierpure.com)
  • The answers did not begin to emerge until the 1930s, when related influenza viruses (now known as H1N1 viruses) were isolated from pigs and then humans. (medscape.com)
  • rather, current influenza outbreaks, including those caused by 2009 H1N1, show an intensity similar to that seen during seasonal epidemics. (uspharmacist.com)
  • Such risk factors did not significantly influence the age-specific death patterns during other pandemics and inter-pandemic influenza epidemics. (hindawi.com)
  • Pregnant women are considered to be at high risk for serious illness due to influenza related mortality and morbidity documented during influenza pandemics and seasonal epidemics. (bmj.com)
  • How does the early occurrence of influenza epidemics impact outbreaks of other common seasonal viruses? (medscape.com)
  • Every year, throughout the world, widespread outbreaks of influenza occur during late fall or early winter in temperate climates (called seasonal epidemics). (msdmanuals.com)
  • Age-Dependent Estimates of the Epidemiological Impact of Pandemic Influenza (H1N1-2009) in Japan by: Kenji Mizumoto, et al. (uitm.edu.my)
  • On 25 May 2009, Kuwait and the United Arab Emirates reported confirmed cases of influenza due to pandemic (H1N1) 2009, the first two countries in the Region to do so. (who.int)
  • Our objective was to determine the risk factors associated to mortality in suspected cases of influenza A (H1N1) in Paraguay. (bvsalud.org)
  • Up to January 30, 2010, 8,303 suspected cases of influenza A (H1N1) were reported to the Dirección General de Vigilancia de la Salud. (bvsalud.org)
  • One of the most pressing scientific questions of the epidemiology of Spanish influenza is the atypical W-shaped curve seen in the age-specific mortality [ 3 , 4 ]. (hindawi.com)
  • As a result of low incidence of H1N1, the project switched focus to add the monitoring of the measles outbreak, making it the first genomic epidemiology study of a measles outbreak. (genomebc.ca)
  • Washington, DC- According to the World Health Organization (WHO) International Health Regulations Emergency Committee and WHO Director-General Margaret Chan, MD, the 2009 H1N1 influenza pandemic is over. (uspharmacist.com)
  • After global spread, the World Health Organization in June declared the first influenza pandemic in 41 years. (scienceopen.com)
  • On 11 June 2009, the World Health Organization declared the first influenza pandemic since 1968. (who.int)
  • The World Health Organization Collaborating Centre for Reference and Research on Influenza tested 403 isolates of which 261 were positive for influenza, 250 of which were influenza A and 11 were influenza B. Ninety-two per cent of the influenza A viruses were pandemic A(H1N1) 2009, and following antigenic analysis all of these were found to be similar to the current vaccine strain. (who.int)
  • In August 2010, the World Health Organization announced that pandemic H1N1 (pH1N1) had moved into the post-pandemic period, although localized outbreaks of various magnitudes continue to occur. (biomedcentral.com)
  • abstract = "In the past, influenza pandemics have been occurring every 20 to 30 years. (elsevierpure.com)
  • abstract = "Background: A novel variant of influenza A (H1N1) is causing a pandemic and, although the illness is usually mild, there are concerns that its virulence could change through reassortment with other influenza viruses. (psu.edu)
  • abstract = "Pandemic (H1N1) 2009 poses a serious global health threat. (elsevierpure.com)
  • Three pieces of epidemiological information were assessed: (i) the epidemic records containing the age-specific numbers of cases and deaths of influenza from 1918-19, (ii) an outbreak record of influenza in a Swiss TB sanatorium during the pandemic, and (iii) the age-dependent TB mortality over time in the early 20th century. (hindawi.com)
  • Results: In the absence of effective interventions, the model predicts that the introduction of pandemic H1N1 will result in an epidemic that spreads to half of Vietnam's provinces within 57 days (interquartile range (IQR): 45-86.5) and peaks 81 days after introduction (IQR: 62.5-121 days). (psu.edu)
  • A large epidemic in a country with intense human-animal interaction and continued co-circulation of other seasonal and avian viruses would provide substantial opportunities for H1N1 to acquire new genes. (psu.edu)
  • Since 2009, three pH1N1 influenza epidemic outbreaks have occurred in Shenzhen, China . (bvsalud.org)
  • A pandemic is a major worldwide epidemic. (msdmanuals.com)
  • In an influenza epidemic, many people get sick within a very brief period of time. (msdmanuals.com)
  • Thus, it becomes imperative to investigate herd immunity in humans to swine and avian influenza viruses of subtypes H1 and H3. (cdc.gov)
  • Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. (cdc.gov)
  • This pandemic (H1N1) 2009 is also not as virulent as A(H5N1) in humans. (elsevierpure.com)
  • Transmission of swine influenza viruses to humans is uncommon. (medscape.com)
  • The ability to trace outbreaks of swine flu in humans dates back to investigation of the 1918 Spanish influenza pandemic, which infected one third of the world's population (an estimated 500 million people) and caused approximately 50 million deaths. (medscape.com)
  • In humans, the severity of swine influenza can vary from mild to severe. (medscape.com)
  • This declaration was based on strong indications that, worldwide, influenza is transitioning toward seasonal patterns of transmission. (uspharmacist.com)
  • Out-of-season 2009 H1N1 outbreaks are no longer being seen in most countries, and the intensity of transmission is lower than that reported in 2009 and early 2010. (uspharmacist.com)
  • Entry screening to delay local transmission of 2009 pandemic influenza A (H1N1) by: Wong Helen WC, et al. (uitm.edu.my)
  • A continuous surveillance by public health authorities will be critical to monitor the appearance of new influenza variants, especially in animal reservoirs such as swine and birds, in order to prevent the potential animal-human transmission of viruses with pandemic potential. (benthamopen.com)
  • Transmission characteristics of the 2009 H1N1 influenza pandemic: comparison of 8 Southern hemisphere countries. (ox.ac.uk)
  • To explore the role of demography in explaining differences in transmission intensity, we then fitted a dynamic age-structured model of influenza transmission to available incidence data for each country independently, and for all the countries simultaneously. (ox.ac.uk)
  • Highly pathogenic avian influenza A(H5N1) has been causing unprecedented global outbreaks since 2003 and many human cases with a high case fatality rate have also been reported. (elsevierpure.com)
  • The pandemic outbreak of the H1N1 Influenza in 2009 is a painful illustration of the deficiency current national and international health organizations have in rapid diagnostics, prevention and efficient therapeutics offered to large populations. (dubowski.ca)
  • Estimating effect of antiviral drug use during pandemic (H1N1) 2009 outbreak, United States. (blogspot.com)
  • A 1976 outbreak of swine influenza in Fort Dix, New Jersey, involved more than 200 cases, some of them severe, and one death. (medscape.com)
  • Some patients with influenza develop rhinitis of varying severity, but it generally is not the chief symptom. (medscape.com)
  • The newly emerged pandemic (H1N1) 2009 is different from H5N1 in terms of severity and requires different approaches. (elsevierpure.com)
  • There are several factors that can potentially affect the severity of pandemic (H1N1) 2009, including a population's vulnerability and response capacity. (elsevierpure.com)
  • The overall impact of pandemic (H1N1) 2009 remains unknown and it is difficult to assess its severity. (elsevierpure.com)
  • Understanding the most serious pandemic and its epidemiological features is crucial for elucidating the mechanisms of severe influenza outcomes and possibly planning effective countermeasures in the future. (hindawi.com)
  • When patients with severe influenza A(H1N1)-related ARDS treated with ECMO were compared with conventionally treated patients, no difference in mortality rates existed. (nih.gov)
  • Read about the Global Influenza Hospital Surveillance Network, a new platform that can provide annual data on severe influenza for a wide range of populations. (medscape.com)
  • The Company is also the only supplier of the H5N1 pandemic influenza vaccine, Panflu ® , to the Chinese government stockpiling program. (sinovac.com)
  • However, these plans have focused on surveillance for and response to the highly pathogenic avian influenza (H5N1), including the rapid containment of H5N1. (elsevierpure.com)
  • How safe and effective is the AS03-adjuvanted H5N1 influenza vaccine in children? (medscape.com)
  • Many patients with severe acute respiratory distress syndrome (ARDS) caused by influenza A(H1N1) infection receive extracorporeal membrane oxygenation (ECMO) as a rescue therapy. (nih.gov)
  • Influenza and Other Respiratory Viruses, February 2012, Wiley, DOI: 10.1111/j.1750-2659.2012.00347.x. (growkudos.com)
  • Both 2009 H1N1 influenza and COVID-19 are respiratory infections that share many symptoms in common. (healthline.com)
  • PURPOSE: In view of the expected 2009 influenza A(H1N1) pandemic, the Italian Health Authorities set up a national referral network of selected intensive care units (ICU) able to provide advanced respiratory care up to extracorporeal membrane oxygenation (ECMO) for patients with acute respiratory distress syndrome (ARDS). (uniroma1.it)
  • Swine flu is a highly contagious respiratory disease in pigs caused by one of several swine influenza A viruses (see the image below). (medscape.com)
  • Acute febrile respiratory illness in a person who resides in a community where at least one H1N1 influenza case has been confirmed. (medscape.com)
  • Also, influenza affects cells much deeper down in the respiratory tract. (msdmanuals.com)
  • Reports from Public Health Labs participating in CDC's part of the WHO Global Influenza Surveillance Network. (cdc.gov)
  • Surveillance for Influenza-associated Pediatric MortalityInfluenza-associated deaths in children (persons less than 18 years) was added as nationally notifiable condition in 2004. (cdc.gov)
  • This article synthesizes and extends discussions held during an international meeting on "Surveillance for Decision Making: The Example of 2009 Pandemic Influenza A/H1N1," held at the Center for Communicable Disease Dynamics (CCDD), Harvard School of Public Health, on June 14 and 15, 2010. (nih.gov)
  • We define the needs for surveillance in terms of the key decisions that must be made in response to a pandemic: how large a response to mount and which control measures to implement, for whom, and when. (nih.gov)
  • We describe other inputs to decision making besides epidemiologic and surveillance data, and we conclude with key lessons of the 2009 pandemic for designing and planning surveillance in the future. (nih.gov)
  • This genomic and metagenomic research project aimed to pilot a genomic surveillance program for influenza. (genomebc.ca)
  • Clinical and epidemiological data were obtained through the surveillance system of influenza A (H1N1) established in the country by the Ministry of Public Health and Social Welfare on April 28, 2009. (bvsalud.org)
  • CONCLUSIONS: Immunocompromised children infected with pandemic 2009 influenza may respond very well when the diagnosis and treatment are rapid. (edu.lb)
  • Included were all consecutive adult patients who presented to the emergency department (ED) between May-December, 2009 with a flu-like illness, a confirmed diagnosis of pandemic influenza A (H1N1) infection and a serum CRP level measured within 24 hours of presentation. (scienceopen.com)
  • Invasive aspergillosis may occur in severely immunocompromised patients hospitalized with pandemic influenza A (H1N1), highlighting the need for early diagnosis and prompt treatment. (consensus.app)
  • Sixty patients (48 of the referred patients, 49 with confirmed H1N1 diagnosis) received ECMO according to ECMOnet criteria. (uniroma1.it)
  • The peak of the first pandemic wave in Hong Kong occurred in September 2009. (cdc.gov)
  • Conclusions No associations were observed between exposure to pH1N1 influenza vaccine during pregnancy and most five year pediatric health outcomes. (bmj.com)
  • A 2012 study in Denmark found no evidence of an increased risk of fetal death associated with exposure to an adjuvanted pandemic A/H1N1 2009 influenza vaccine during pregnancy. (medscape.com)
  • The putational scheme to identify host-specifi c genomic signa- genomic sequences of many of the new strains of pandemic tures of human and avian infl uenza viruses ( 4 ). (cdc.gov)
  • From time to time new strains emerge and cause global pandemics. (cambridge.org)
  • The pattern of age-dependent susceptibility found confirms that older populations had substantial--though partial--pre-existing immunity, presumably due to exposure to heterologous influenza strains. (ox.ac.uk)
  • Similar constraints also influenza strains which cause inflamma- new cases in January 2010. (who.int)
  • There are many different strains within types A and B influenza viruses but all cause similar illness. (msdmanuals.com)
  • It is imperative that content of algorithms and their implementation are critically evaluated in order to optimise any future response to a pandemic, and it should be ensured that a concise history covers prior travel history, immunosuppression and drug exposure comprehensively. (bmj.com)
  • GlaxoSmithKline (GSK) today announced results from its first clinical trial assessing use of its pandemic (H1N1) adjuvanted vaccine. (gsk.com)
  • GSK will continue to work closely with regulators, governments and health authorities around the world, providing them with clinical data which may help them to determine the most appropriate strategy to address the H1N1 pandemic. (gsk.com)
  • In this study, we describe the clinical characteristics of children with hematological malignancies and laboratory-proven H1N1 influenza. (edu.lb)
  • Clinical and molecular characteristics of the 2009 pandemic influenza H1N1 infection with severe or fatal disease from 2009 to 2011 in Shenzhen, China. (bvsalud.org)
  • The National Pandemic Flu Service (NPFS) has issued antiviral drugs to patients with an influenza-like illness who call or log onto the internet site without direct clinical assessment or virological evidence of infection with novel H1N1 (1). (bmj.com)
  • Astafieva, N , Kobzev, D & Tsareva, J 2010, ' The impact of first wave pandemic influenza (A/H1N1) 2009 on asthma-related hospitalisation among children ', Allergy: European Journal of Allergy and Clinical Immunology , vol. 65, no. (leedstrinity.ac.uk)
  • Clinical characteristics of pediatric patients treated for infl uenza A (H1N1). (medigraphic.com)
  • The groups at risk for complications from 2009 H1N1 influenza and COVID-19 have significant overlap. (healthline.com)
  • People most at risk of complications from pandemic influenza were those with significant underlying chronic health conditions, pregnant women and young children. (who.int)
  • Targeted populations recommended to receive the 2009 H1N1 vaccine included pregnant women, household contacts and caregivers of children younger than 6 months, healthcare and emergency medical services personnel, children aged 6 months to 18 years, young adults aged 19-24 years, and persons aged 25 through 64 years with conditions associated with higher risk of medical complications from influenza. (medscape.com)
  • Because the postpandemic serum samples were collected 2-5 months after the peak of the pandemic, waning of antibody titers over a few months is expected to be relatively modest ( 5 ). (cdc.gov)
  • Antibody titers against 2009 H1N1 and three contemporary influenza viruses were measured with the hemagglutination inhibition (HI) assay following standard procedures by Focus Diagnositcs, Inc., Cypress, CA. (cdc.gov)
  • Data from patients admitted for H1N1-associated ARDS to French ICUs were prospectively collected from 2009 to 2011 through the national REVA registry. (nih.gov)
  • CONCLUSIONS: A network organization based on preemptive patient centralization allowed a high survival rate and provided effective and safe referral of patients with severe H1N1-suspected ARDS. (uniroma1.it)
  • ii) Cytokine storm, that is, hyperreaction of the immune system that could potentially cause severe damages in the host, might explain the more severe outcomes observed among young adults (who have stronger immunity) and fewer deaths observed in children and elderly (who have weaker immune system) [ 10 ], although the findings have mainly stemmed from experimental studies of avian influenza in nonhuman hosts. (hindawi.com)
  • Patients with influenza who have preexisting immunity or who have received vaccine may have milder symptoms. (medscape.com)
  • Please see the Centers for Disease Control and Prevention website at http://www.cdc.gov/h1n1flu/ for the latest information about H1N1 flu. (foundhealth.com)
  • Are minority groups more or less likely to adopt influenza prevention behaviors? (medscape.com)
  • The epidemiological mechanisms behind the W-shaped age-specific influenza mortality during the Spanish influenza (H1N1) pandemic 1918-19 have yet to be fully clarified. (hindawi.com)
  • The present study aimed to develop a formal hypothesis: tuberculosis (TB) was associated with the W-shaped influenza mortality from 1918-19. (hindawi.com)
  • Analyzing the data (i), we found that the W-shaped pattern was not only seen in mortality but also in the age-specific case fatality ratio, suggesting the presence of underlying age-specific risk factor(s) of influenza death among young adults. (hindawi.com)
  • The data (iii) were analyzed by employing the age-period-cohort model, revealing harvesting effect in the period function of TB mortality shortly after the 1918-19 pandemic. (hindawi.com)
  • Other pandemic and interpandemic influenza disproportionately killed infants and elderly, most commonly yielding the U-shaped (or J-shaped) age-specific mortality curve. (hindawi.com)
  • Addressing the age-specific excess mortality estimate of the Spanish influenza pandemic using historical baseline, the deaths among the elderly tend to be diminished, but the peak among young adults still remains, suggesting an excess risk of death among those aged 25-35 years [ 5 - 7 ]. (hindawi.com)
  • That is, one of the distinguishing features of the 1918-19 pandemic was the unusually high estimate of mortality among young adults. (hindawi.com)
  • Past pandemics had different impacts on mortality which varied between countries. (elsevierpure.com)
  • The use of algorithms to remotely diagnose and issue antiviral drugs is indispensable during a pandemic where the case burden threatens to paralyse the healthcare system and helps to reduce nosocomial spread. (bmj.com)
  • The real time RT-PCR targeted specific sequences of HA and NA genes for pH1N1 or cH3N2 influenza viruses. (biomedcentral.com)
  • Pulmonary pathologic findings of fatal 2009 pandemic influenza A/H1N1 viral infections. (scienceopen.com)
  • 1%) were influenza A and B co-infections. (who.int)
  • Methods: We developed an age- and spatially-structured mathematical model in order to estimate the potential impact of pandemic H1N1 in Vietnam and the opportunities for reassortment with animal influenza viruses. (psu.edu)
  • Ocular symptoms develop in some patients with influenza and include photophobia, burning sensations, or pain upon motion. (medscape.com)
  • The North-East of England had the lowest case burden of H1N1 in England during this study period (5), both in the community and amongst hospital admissions with fever and flu-like-symptoms. (bmj.com)
  • Influenza is often diagnosed based on symptoms. (msdmanuals.com)
  • Main operational lessons learnt from the WHO pandemic influenza A(H1N1) vaccine deployment initiative. (who.int)
  • These estimates were derived using combined data from two sources: 1) an unpublished CDC model for estimating the impact of the 2009 H1N1 pandemic influenza vaccine on averting cases, hospitalizations, and deaths during the 2009--10 influenza season and 2) a model for estimating the impact of antiviral treatment in averting hospitalizations and deaths during the 2009--10 season ( 2 ). (blogspot.com)
  • The most devastating pandemic known in human history is the Spanish influenza 1918-19. (hindawi.com)
  • This is of greater concern in parts of Southeast Asia, where the population density is high, influenza is less seasonal, human-animal contact is common and avian influenza is still endemic. (psu.edu)
  • This new variant was formed by a triple reassortment, with genomic segments from swine, avian, and human influenza origins. (benthamopen.com)
  • In 1918, the cause of human influenza and its links to avian and swine influenza was not understood. (medscape.com)
  • In 2006, the NIEHS Worker Training Program (WTP) awarded four avian and pandemic influenza preparedness training supplemental grants to augment WTP training programs with modules and outreach information to protect potential high-risk populations involved in pandemic and avian influenza preparedness and response. (nih.gov)
  • Even before the influenza pandemic was officially declared, the Regional Office focused efforts on improving the capacities of Member States to respond effectively to pandemic influenza and thereby limit its adverse health consequences on their populations. (who.int)
  • In October, 1976, approximately 40 million people received the A/NewJersey/1976/H1N1 vaccine (ie, swine flu vaccine) before the immunization initiative was halted because of the strong association between the vaccine and Guillain-Barré syndrome (GBS). (medscape.com)