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  • purine
  • The sugar molecules are modified by the presence of a purine or pyrimidine nucleoside or "base" attached to the first, or 1', carbon and the oxygen-phosphorus-oxygen bond links the third, or 3', carbon to the fifth, or 5', carbon of the adjacent sugar molecule. (factbites.com)
  • Carbon 1 of the sugar is attached to nitrogen 9 of a purine base or to nitrogen 1 of a pyrimidine base. (utah.edu)
  • proteins
  • The addition of these sugar moieties at precise locations of complex molecules such as proteins or lipids serves many different functions: proper protein folding, protein stability, protein targeting into appropriate cellular compartments like the endoplasmic reticulum, immunological specifications etc. (perlara.com)
  • Organisms also often form glycoproteins by attaching sugars to proteins via O- or N-glycosidic bonds in a process known as glycosylation . (chemeurope.com)
  • phosphatase
  • Exopolyphosphatases (Ppx) is involved in the degradation of inorganic polyphosphates [ PMID: 8380170 ] and belongs to the same family as the guanosine pentaphosphate phosphatase [ PMID: 8212131 ]. (ebi.ac.uk)
  • Exopolyphosphate phosphatase and guanosine pentaphosphate phosphatase belong to the sugar kinase/actin/hsp 70 superfamily. (ebi.ac.uk)
  • fucose
  • A nucleoside diphosphate sugar which can be converted to the deoxy sugar GDPfucose, which provides fucose for lipopolysaccharides of bacterial cell walls. (definitions.net)
  • I. To evaluate the safety and feasibility of transplantation of cord blood which is expanded in mesenchymal precursor cell (MPC) co-cultures then fucosylated with fucosyltransferase (FT)-VI and guanosine diphosphate (GDP) fucose prior to infusion in patients with hematologic malignancies following high-dose therapy. (clinicaltrials.gov)
  • hydroxyl
  • 2'-GMP would indicate that a phosphate is in ester linkage to the 2' hydroxyl group of a guanosine. (utah.edu)
  • An α-glycosidic bond for a D-sugar emanates below the plane of the sugar, whereas the hydroxyl (or other substituent group) on the other carbon points above the plane (opposite configuration), while a β-glycosidic bond emanates above that plane (the same configuration). (chemeurope.com)
  • molecule
  • The nucleotide molecule contains three functional groups: a base, a sugar, and a phosphate (see diagram). (encyclopedia.com)
  • In chemistry , a glycosidic bond is a certain type of functional group that joins a carbohydrate (sugar) molecule to another, which may be another carbohydrate. (chemeurope.com)
  • Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the "stringent response", an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. (ebi.ac.uk)
  • Their carbon atoms are numbered: the 5' carbon atom is always on the side of the sugar molecule that faces the leading end, while the 3' carbon atom always faces the tail end. (chemicalland21.com)
  • Gene
  • To test this model, we cloned the gene for the S. cerevisiae guanosine diphosphatase and constructed a null mutation. (umassmed.edu)
  • bound
  • In contrast, Gly12 p21 was predominantly guanosine diphosphate (GDP)-bound because of a dramatic stimulation of Gly12 p21-associated guanosine triphosphatase ( GTPase ) activity. (factbites.com)
  • In analogy, one also considers S-glycosidic bonds , where the anomeric carbon of a sugar is bound to some other group via a sulfur (rather than an oxygen ) atom, and N-glycosidic bonds , where the anomeric carbon is bound to some other group via a nitrogen atom. (chemeurope.com)
  • atoms
  • The convention is to number the ring atoms of the base normally and to use l', etc. to distinguish the ring atoms of the sugar. (utah.edu)