• the source of the guanosine found in RNA and also involved in many cellular processes, including microtubule assembly, protein synthesis , and cell signaling, due to the energy it releases upon removal of its terminal phosphate group (yielding GDP). (factbites.com)
  • Guanosine (G 1), in particular, is unique in that it has multiple faces for noncovalent interactions and can self-associate into stable higher-order assemblies, such as G4-quartets and G-quadruplexes. (umd.edu)
  • Guanosine is required for an RNA splicing reaction in mRNA, when a "self-splicing" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein. (wikipedia.org)
  • 7-thia-8-oxoguanosine (TOGuo) is the first reported structure of a family of modified guanosine analogues exhibiting antiviral activity in rodent models. (hindawi.com)
  • The antiviral drug acyclovir , often used in herpes treatment, and the anti-HIV drug abacavir , are structurally similar to guanosine. (wikipedia.org)
  • Several related guanosine analogues show similar antiviral and immunoenhancing properties, including 7-methyl-8-oxoguanosine, 7-methyl-8-thioxoguanosine and 7-deazaguanosine. (hindawi.com)
  • Assembly of v-SNARE-t-SNARE targeting complexes is modulated by members of the Sec1-Sly1 protein family, and by small guanosine triphosphatases termed Rabs. (sciencemag.org)