The DUF582 proteins of Chlamydia trachomatis bind to components of the ESCRT machinery, which is dispensable for bacterial growth in vitro. (pasteur.fr)
Our lab conducts biomedical research directed to establish the metabolic strategies and host- pathogen relationship in bacterial pathogenic species, such as Chlamydia trachomatis , the most prevalent sexually transmitted disease in the world, and Vibrio cholerae , which produces severe gastrointestinal disease to millions of people in developing countries. (iit.edu)
Instead, the presence of a greater than 10-fold bacterial growth in the EPS or the third midstream bladder specimen (VB 3 ) compared with the first voided bladder specimen (VB 1 ) and the second midstream bladder specimen (VB 2 ) is important. (medscape.com)
ABSTRACT Optical density is a proxy of total biomass concentration and is commonly used for measuring the growth of bacterial cultures. (microbial-ecology.net)
Conversely, bacterial growth within cholesterol-leaden macrophages was enhanced. (microbialcell.com)
Dr. Maurelli has over 30 years of research experience in the field of molecular genetics of bacterial pathogenesis, specifically in the study of Shigella and Chlamydia. (ufl.edu)
Chromosomal1
Moreover Chlamydia psittaci could promote chromosomal aberration either through genetic instability as a consequence of induced proliferation and probably through DNA oxidative damage. (biomedcentral.com)
Proteins1
Localization of organelle proteins by isotope tagging (LOPIT). (joplink.net)
Species1
Growth in this species, as well as all species of mycoplasmas, is driven by anaerobic respiration. (wikipedia.org)
Ocular3
Chlamydia trachomatis causes both genital tract and ocular diseases. (ku.edu)
Recently Chlamydia psittaci has been identified in Ocular Adnexa MALT lymphomas, with variable frequence dependently from geographic areas. (biomedcentral.com)
In this review we analyse the most relevant features of Ocular adnexa MALT lymphomas, underlining specific biological characteristics mainly related to the potential role of Chlamydia psittaci in lymphomagenesis. (biomedcentral.com)
Infection4
According to the CDC, C. trachomatis has the highest incidence of infection among ALL reportable infectious diseases in the US! (ku.edu)
Despite excellent educational and awareness programs, conditional prevention strategies are insufficiently addressing the public health challenge associated with Chlamydia infection rates. (ku.edu)
Depending on PAMP/DAMP nature and localization, autophagy can selectively capture bacteria, such event is called xenophagy, damaged organelles, and other signaling platforms activated during the infection ( 4 , 5 ). (frontiersin.org)
He has served as Secretary-Treasurer of the Chlamydia Basic Research Society and Mini-reviews Editor for Infection and Immunity. (ufl.edu)
Metabolism3
Liang P, Rosas-Lemus M, Patel D, Fang X, Tuz K, Juárez O (2017) Dynamic Energy Dependency of Chlamydia trachomatis on Host Cell Metabolism during Different Stages of Intracellular Growth: Possible role of Sodium -based energetics in Chlamydial ATP generation. (iit.edu)
Lipid metabolism is pivotal for the growth of apicomplexan parasites. (biomedcentral.com)
Lipids are crucial to the biology of all cells and organisms, acting not only as primary sources of energy but also as regulators of metabolism and growth, participating in various signaling networks [ 4 ]. (biomedcentral.com)
Bacteria1
Chlamydia (klah-MID-e-a) are obligate intracellular bacteria that are propagated and maintained through a phylum defining bi-phasic developmental cycle. (ku.edu)
Sexually3
BACKGROUND: National guidelines recommend sexually active women under the age of 25 be screened annually for chlamydia. (cdc.gov)
Our objective was to estimate the chlamydia screening rate of sexually active women aged 16-24 years from 2011-2020. (cdc.gov)
Chlamydia is a major cause of sexually transmitted infections worldwide. (ufl.edu)
Inclusion1
After directing entry into a eukaryotic cell, the EBs quickly modifies the early endosome into a Chlamydia specific vessicle termed an inclusion. (ku.edu)
Cultures3
Cells of M. hominis prepared from batch cultures show uniform exponential growth and appear to divide through the process of binary fission with pleomorphic forms appearing upon further incubation. (wikipedia.org)
Localization cultures do not need to demonstrate more than 100,000 colony-forming units (CFU) per milliliter to establish the diagnosis (see the image below). (medscape.com)
Importantly, the growth benefit of cholesterol was observed strictly in cellular infections and L. pneumophila growth kinetics in axenic cultures did not change in the presence of cholesterol. (microbialcell.com)
Strains2
Antibiotic resistance is a major public health threat and while two major classes of antibiotics (e.g., macrolides and tetracyclines) are effective at clearing Chlamydia infections, resistance to one of these has already been observed in pigs strains (yes…there is pig Chlamydia ! (ku.edu)
E. coli strains bearing the dnaN159 allele display temperature-sensitive growth ( 14 , 35 , 38 ) and altered DNA polymerase (Pol) usage ( 29 , 38 - 40 ). (asm.org)
Infections1
Development of a vaccine has been hindered by the lack of vertebrate animal models that more closely mimics human immune responses as well as characterization of the correlates for immunity to human Chlamydia infections. (ku.edu)
Zona1
Since it is formed at an early stage in women harbouring ASA and AZP-Ab in of oocyte growth, zona pellucida-specific their cervical secretions. (who.int)
Phenotype2
Our study demonstrated that genetic ablation of NcACBP did not impair the survival and growth phenotype of N. caninum but enhanced its pathogenicity in mice. (biomedcentral.com)
Our findings indicate that elevated levels of Pol I partially suppress the temperature-sensitive growth phenotype of the dnaN159 strain. (asm.org)
Exponential1
However, there is a misconception that exponential optical density growth is equivalent to steady-state population growth. (microbial-ecology.net)
Cell2
Studies in infectious disease models have provided a wealth of information regarding memory CD8 T cell generation and localization. (frontiersin.org)
In addition, mannosebinding-lectin (MBL) is an epithelial-cell associated host protein that binds to Candida mannan, activates complement, and thus inhibits Candida growth. (paperzz.com)
Glucose2
Growth of "fried egg" colonies on glucose agar medium within 24-48 hours is a characteristic of Mycoplasma hominis. (wikipedia.org)
Glucose- or phosphate-limited growth produced frequent genomic amplifications, rearrangements and novel retrotransposition. (uchicago.edu)
Rates1
Among STI testing-eligible PrEP users who had 14 days between runout and next refill date, gonorrhea and chlamydia screening testing rates were 95.1% for prepandemic and 93.4% for early pandemic ( P = 0.1011). (cdc.gov)
Research1
There are many priorities and challenges associated with Chlamydia research. (ku.edu)
Site1
2013) The Joubert Syndrome Associated Missense Mutation (V443D) in the Abelson-helper Integration Site 1 (AHI1) Protein Alters Its Localization and Protein-Protein Interactions. (iit.edu)
Early1
Among all STI testing-eligible PrEP users who were tested for gonorrhea and chlamydia, gonorrheaprevalence was 6.7% for prepandemic and 5.7% for early pandemic ( P = 0.3096), and chlamydiaprevalence was 7.0% for prepandemic and 5.8% for early pandemic ( P = 0.2158). (cdc.gov)
Agent1
In Neospora caninum , the causative agent of neosporosis, the FASII pathway is required for growth and pathogenicity. (biomedcentral.com)
Conditions1
In contrast to these three Pols, which under certain conditions impede growth of the dnaN159 strain ( 29 , 39 , 40 ), presumably by impairing DNA replication, the catalytic DNA polymerase activity of Pol I ( polA ) is essential for viability of the dnaN159 strain ( 38 ). (asm.org)
Addition1
These growth defects were rescued by addition of exogenous cholesterol. (microbialcell.com)