Growth and cell. Medical search. Frequent questions

It may also be possible to convert spermatogonial stem cells to totipotent cells, capable of becoming almost any other cell type and similar to embryonic stem cells. (scienceblog.com)
Human embryonic stem cells have a lot of potential for treatment and could become the global standard for these diseases. (expertmarketresearch.com)
Hence, these factors are expected to influence the growth of the human embryonic stem cells industry over the forecast period. (expertmarketresearch.com)
As embryonic cells offer unmatched data related to a variety of diseases, researchers and scientists are increasingly leaning toward transforming the human embryonic stem cells into a range of mature cell types that represent different organs and tissues in the body. (expertmarketresearch.com)
Advancements in stem culturing and derivation, along with rapid progress in laboratory technologies, are expected to play a key role in the overall growth of the global human embryonic stem cells industry during the forecast period. (expertmarketresearch.com)

New data shows that proanthocyanidins, or PACs, found in cranberries inhibit the growth of lung tumors and colon and leukemia cells in vitro. (news-medical.net)
explains the growth of cancerous tumors. (medlineplus.gov)
In mice, researchers have discovered the presence of oncostreams, highly active cells connected to how brain tumors grow and invade healthy tissue. (newswise.com)
Newswise - Tumors are made up of many types of cells, both cancerous and benign. (newswise.com)
The specific complexity of the cells inside brain tumors has been a trademark of the disease, one that makes treatment extremely difficult. (newswise.com)
While scientists have long known about the variety of cells within a brain tumor, the ways these tumors grow has relied on the understanding that the cells are static, unmoving and relatively fixed. (newswise.com)
But researchers at the University of Michigan Department of Neurosurgery and Rogel Cancer Center have discovered that these aggressive tumors contain highly active cells that move throughout tissue in complicated patterns. (newswise.com)
What's more, the accumulations of these elongated, spindle-like cells found throughout the tumor, coined 'oncostreams,' serve as the basis for cancerous cells' behavior, determining how tumors grow and invade normal tissue. (newswise.com)
Pedro Lowenstein, M.D., Ph.D. , Richard C. Schneider Collegiate Professor of Neurosurgery and lead author of this study in Nature Communications , says this organized growth is what makes brain tumors so relentless. (newswise.com)
When we eliminated Collagen 1 production from tumor cells, the animal models with brain tumors lived much longer. (newswise.com)
The rate of cell division varies among tumors. (medscape.com)
Most lesions of common cancers increase very slowly in size compared to normal tissues, and the rate of growth may even be slower in large tumors. (medscape.com)
Their study, published in the ACS journal Chemical Research in Toxicology , found that triclosan, as well as another commercial substance called octylphenol, promoted the growth of human breast cancer cells in lab dishes and breast cancer tumors in mice. (medindia.net)
Mechanisms of tumorigenesis and novel cancer therapies have been investigated in cultured mutant cells, genetically engineered to develop tumors, but the behaviour of these cells in a normal tissue environment remains almost completely unknown. (the-scientist.com)
The membranous location of TbetaR-II in VC exposes the receptor to the growth inhibitory control of TGF-beta and may explain why VC tumors are less aggressive clinically. (nih.gov)
While two-dimensional (2D) cell culture has led to remarkable advances in the study of cancer, cancer cells grown in monolayer frequently do not reflect the intrinsic drug resistance observed in tumors in vivo. (nih.gov)
The study shows that ccRCC tumors acquire specific mutations that encourage uncontrollable growth and shifts in energy use and production [1]. (nih.gov)

This study is a significant step toward helping to establish a body of research that shows cranberry PACs may also work to prevent tumor cell growth in vivo. (news-medical.net)
Cancer chemotherapy is based on an understanding of tumor cell growth and how drugs affect this growth. (medscape.com)
Although further studies revealed that rottlerin regulated multiple signaling pathways to suppress tumor cell growth, the exact molecular insight on rottlerin-mediated tumor inhibition is not fully elucidated. (harvard.edu)

If a cell has an error in its DNA that cannot be repaired, it may undergo self-destruction ( apoptosis ). (medlineplus.gov)
Apoptosis is a common process throughout life that helps the body get rid of cells that no longer work or that it doesn't need. (medlineplus.gov)
Apoptosis protects the body by removing genetically damaged cells that could lead to cancer, and it plays an important role in the development of the embryo and the maintenance of adult tissues. (medlineplus.gov)
Cellular apoptosis (ie, programmed cell death) is also a potential mechanism in many antineoplastic agents. (medscape.com)
In the 1970s, scientists showed that a type of programmed cell death called apoptosis plays a key role in development, and the 2002 Nobel Prize in physiology or medicine recognized their work. (harvard.edu)
When these cells become detached from their protein-rich beds, they generally die through apoptosis. (harvard.edu)
Overholtzer stained the suspended cells for a protein associated with apoptosis to confirm that it was not playing a role. (harvard.edu)
In the current study, we determine the function of rottlerin on glioma cell growth, apoptosis, cell cycle, migration and invasion. (harvard.edu)
We found that rottlerin inhibited cell growth, migration, invasion, but induced apoptosis and cell cycle arrest. (harvard.edu)
In line with this, over-expression of Cdc20 decreased rottlerin-induced cell growth inhibition and apoptosis, whereas down-regulation of Cdc20 by its shRNA promotes rottlerin-induced anti-tumor activity. (harvard.edu)
The effect of BMSCs-EVs on ALL cell proliferation and apoptosis was evaluated. (karger.com)
The effect of miR-29b-3p on ALL cell proliferation and apoptosis was assessed after silencing miR-29b-3p. (karger.com)
The role of GDF15 in proliferation and apoptosis of ALL cells was further confirmed, and Western blot assay was performed to measure MAPK pathway-related protein levels. (karger.com)
BMSC-derived EVs inhibited proliferation and promoted apoptosis of ALL cells, as shown by the up-regulation of caspase-3 and Bax expressions and down-regulation of Bcl-2 expression. (karger.com)
BMSCs-EVs carried miR-29b-3p into ALL cells, upregulated miR-29b-3p, and inhibited GDF15 to suppress the MAPK pathway and further inhibit proliferation and promote apoptosis of ALL cells. (karger.com)
Exosomes from mesenchymal stromal cells enhance imatinib-induced apoptosis in human leukemia cells via activation of caspase signaling pathway. (karger.com)
Treatment with 50 mg/kg SFN significantly inhibited KPL-1 cell growth in vivo by suppressing cell proliferation and inducing apoptosis, and it tended to reduce axillary lymph node metastasis of KPL-1 human breast cancer cell xenografts in female athymic mice. (nih.gov)
The main types of stem cell assays market are cell viability and toxicity assays, cell apoptosis assays, cell function assays, cell identification assays, isolation and purification assays, cell differentiation assays, and others. (thebusinessresearchcompany.com)

Inhibits topoisomerase II and causes DNA strand breakage causing cell proliferation to arrest in late S or early G2 portion of the cell cycle. (medscape.com)

In multicellular organisms, tissue growth rarely occurs solely through cell growth without cell division, but most often occurs through cell proliferation. (wikipedia.org)
This principle leads to an exponential increase of tissue growth rate (mass accumulation) during cell proliferation, owing to the exponential increase in cell number. (wikipedia.org)
To help heal damaged hearts, scientists have been searching for a group of cells in the heart that can replenish damaged tissue. (nih.gov)
Studying heart tissue and cell turnover rate is technically very challenging. (nih.gov)
In tests on human breast cancer cells and in special immunodeficient mice with tissue grafts, the scientists found that both agents interfered with genes involved with breast cancer cell growth, resulting in more cancer cells. (medindia.net)
Over time, accumulation of senescent cells may slow or stop cell regeneration and tissue maintenance, thus contributing to tissue aging. (nih.gov)
Overholtzer discovered entosis while working with human breast cells that normally form sheets of tissue. (harvard.edu)
The prostates of older mice contain more luminal progenitor cells - cells capable of generating new prostate tissue - than the prostates of younger mice, UCLA researchers have discovered. (ucla.edu)
For instance, prostate progenitor cells can only form prostate tissue. (ucla.edu)
We thought it was a real possibility that older cells would have a reduced capacity to generate prostate tissue when we took them out of the prostate," said Goldstein, who is also a member of the UCLA Jonsson Comprehensive Cancer Center . (ucla.edu)
So it was a surprising and important finding that there's really no difference between old cells and young cells in their ability to form prostate tissue. (ucla.edu)
The higher concentration of luminal progenitors, coupled with their maintained ability to form new tissue, helps explain why the prostate grows with age and why the risk of prostate cancer and benign prostatic hyperplasia increase: Both are associated with the growth of cells. (ucla.edu)
Though platelets are best known for blood clotting, they also contain proteins known as "growth factors," which play a critical role in tissue repair and regeneration. (medium.com)
It is very versatile as it has the ability to divide itself into more stem cells and can even become any type of cell in the human body and can be used to regenerate or repair any diseased tissue or organs. (expertmarketresearch.com)
But that's all changed because studies show that the stems cells in your body can become any type of cell, including penis tissue cell. (lakeportchamber.com)
Penis Enlargement Remedy is a comprehensive guide that teaches you all-natural, safe male enhancement techniques that send stem cells from your body to become penis tissue cells, which results in added length and girth. (lakeportchamber.com)

Researchers have identified two types of cells in our brains that are involved in organizing discrete memories based on when they occurred. (nih.gov)
However, the researchers also noted that many cells had taken up 15 N but not completed cell division. (nih.gov)
The researchers then pharmacologically disrupted the herringbone pattern in a normal plant's cell walls, which prevented cells from growing normally even in the presence of a growth hormone. (sciencedaily.com)
Based on their study, the researchers believe that CSI1 and the crossed-polylamellate wall structure are critical to the elongation of cells and suggest that existing theories about cell growth -- as well as the analogy of rings on a barrel -- are incomplete. (sciencedaily.com)
In combination with fluorescent fusion proteins, mutational analysis, and chemical perturbations, this methodology will allow a comprehensive analysis of the regulation and coordination of bacterial growth," the researchers note. (acs.org)
By tagging both mouse cells and UPEC with light-emitting molecules and other visually detectable markers, the researchers were able to track the primary source of LCN2 during an infection to cells in the kidney called alpha-intercalated cells. (nih.gov)
The researchers created about 500 polymers (long chains of repeating molecules) that varied in those traits, grew stem cells on them and analyzed each polymer's performance. (medgadget.com)
Using their best-performing material, the researchers got stem cells (both embryonic and induced pluripotent) to continue growing and dividing for up to three months. (medgadget.com)
Researchers have identified the growth factors essential to allow spermatogonial stem cells - the continually self-renewing cells that produce sperm - to exist in culture indefinitely. (scienceblog.com)
According to the researchers, this development will have profound consequences for future fertility therapies and provide a source of stem cells that will make it possible to modify genes from males before they are passed to the next generation. (scienceblog.com)
The Penn researchers then used a GFP marker gene in the cultured stem cells to identify the cells before transplanting them back into infertile mice. (scienceblog.com)
The on switches (also called enhancers or regulatory elements) activated the copied oncogene and were critical for driving the cancer's growth , the researchers found. (cancer.gov)
The researchers believe that the number and variety of switches are optimized to help the cancer cells survive and grow, Dr. Scacheri explained. (cancer.gov)
Given that link, researchers are investigating whether endocrine-disrupting chemicals (EDCs), which are compounds that act like hormones, might spur cancer cell growth. (medindia.net)
Researchers establish connections between Alzheimer's-linked genetic alterations and the functioning of brain cells. (medindia.net)
The researchers demonstrated that PKM2 is essential for epidermal growth factor receptor (EGFR)-promoted beta-catenin activation, which leads to gene expression, cell growth and tumor formation. (mdanderson.org)
The senolytic drug combination of dasatinib and quercetin cleared senescent cells from obese mice in a study by researchers at the Mayo Clinic in Rochester, Minnesota funded by NIA. (nih.gov)
The researchers sought to determine whether anxiety-like behavior in obesity can be caused by increased senescent cell burden. (nih.gov)
Now, Harvard Medical School researchers have uncovered a new type of cell death that is devoid of these features. (harvard.edu)
To begin to demonstrate a causal relationship between these newly generated cells and relief from depression, researchers would have to find a way to prevent their formation in a behaving animal. (biopsychiatry.com)
In the present study, published at the journal Structural Dynamics ( 'Real-time investigation of dynamic protein crystallization in living cells' ), the researchers observed crystal growth in real time, gathering important information about in vivo crystal formation. (nanowerk.com)
The CiQUS researchers detected the spontaneous formation of protein crystals inside cells when expressing two different proteins with the baculovirus system. (nanowerk.com)
The researchers then isolated luminal cells - one subset of prostate cells - from the mice and grew them to form prostate organoids, or smaller, simplified versions of the prostates. (ucla.edu)
Understanding how cancer cells shift into high gear-what makes them become more aggressive and unresponsive to treatment-is a key concern of cancer researchers. (nih.gov)

Some research has hinted that new cells can arise from progenitor cells at a fairly high rate. (nih.gov)
The scientists found that new heart cells were generated from pre-existing cardiomyocytes rather than progenitor cells. (nih.gov)
They are also used to mobilize autologous peripheral blood progenitor cells for bone marrow transplantation and to manage chronic neutropenia. (medscape.com)
In a previous study , McKeown and Cline found that when the tadpoles were deprived of food, their neural progenitor cells stopped dividing and their body growth decreased, but the animals remained alive and their behavior appeared normal. (scripps.edu)
Surprisingly, if tadpoles were able to access food within about nine days, neural progenitor cells in the brain started dividing again and the tadpoles caught up to the growth state where they would have been if food had always been available. (scripps.edu)
What captured McKeown's attention were the life-or-death questions: What triggered the neural progenitor cells to be able to divide again? (scripps.edu)
Interestingly, even without providing the tadpoles with any food, their brains could be relaunched into growth mode by activating the insulin receptor that sits on the surface of neuronal progenitor cells, Cline says. (scripps.edu)
By carefully tracking the neural progenitor cells over time, McKeown also discovered that they were poised to divide as soon as the nutrient signals reached them. (scripps.edu)
The older prostate contains more luminal progenitor cells (brown). (ucla.edu)
Research had previously shown that the numbers of progenitor cells are also diminished in organs that shrink with age. (ucla.edu)
Like stem cells, progenitor cells can differentiate into new cells, but they are more constrained in what type of cells they can become. (ucla.edu)
Whether levels of stem cells or progenitor cells in the prostate changed with age was not previously known. (ucla.edu)
When the team looked more closely at the luminal cells, they discovered that older prostates contained more luminal progenitor cells. (ucla.edu)
One of the biggest questions we have now is what is causing this age-related increase in the number of luminal progenitor cells," Goldstein said. (ucla.edu)
Answering that question, he said, could help identify a way to curb the growth of luminal progenitor cells and, in turn, prevent or treat prostate cancer or benign prostatic hyperplasia. (ucla.edu)

To drive cell growth, the global rate of gene expression can be increased by enhancing the overall rate of transcription by RNA polymerase II (for active genes) or the overall rate of mRNA translation into protein by increasing the abundance of ribosomes and tRNA, whose biogenesis depends on RNA polymerase I and RNA polymerase III. (wikipedia.org)
The Myc transcription factor is an example of a regulatory protein that can induce the overall activity of RNA polymerase I, RNA polymerase II and RNA polymerase III to drive global transcription and translation and thereby cell growth. (wikipedia.org)
The study reveals that the protein CSI1 and the alternating angle of the cell wall's layers, creating a herringbone pattern, are critical for cell growth. (sciencedaily.com)
The team first confirmed that a protein they had previously identified as important to the creation of cellulose -- the main component of cell walls -- is also important to cell growth. (sciencedaily.com)
A mutant form of the model species thale cress, Arabidopsis thaliana, without the protein known as "cellulose synthase interactive 1" (CSI1) showed severely reduced growth, even in the presence of a growth hormone. (sciencedaily.com)
Collagen 1, a protein produced by tumor cells, is essential to the growth and function of these tumor oncostreams. (newswise.com)
Lowenstein and his team, including Maria Castro, Ph.D. , also found that overexpression of Collagen 1, a protein produced by tumor cells, is essential to the growth and function of these structures. (newswise.com)
They found that the best polymers contained a high percentage of acrylates, a common ingredient in plastics, and were coated with a protein called vitronectin, which encourages cells to attach to surfaces. (medgadget.com)
It normally phosphorylates the Cdc2 cell cycle regulatory protein (cyclin-dependent kinase-1, CDK1 ) on a tyrosine residue. (wikidoc.org)
Cell division may be regulated in part by dilution of Wee1 protein in cells as they grow larger. (wikidoc.org)
The protein mTOR is a serine/threonine kinase that regulates translation and cell division [2] . (wikidoc.org)
Fibroblast growth factor 21 (FGF21), a secretion protein, functions as a pivotal regulator of energy metabolism and is being considered as a therapeutic candidate in metabolic syndromes. (hindawi.com)
Initial studies in our laboratory demonstrated that ROS stimulate cultured VSMC proliferation and activate intracellular kinases such as mitogen activated protein kinases (MAPK) which are associated with proto-oncogene expression and cell growth. (bmj.com)
Microgravity-induced bone loss in space, can be reduced by systemic delivery of NELL-1, a protein required for bone growth and its maintenance. (medindia.net)
In response to epidermal growth factor (EGF), the team found, PKM2 moves into the cell nucleus and binds to beta-catenin that has had a phosphate atom and three oxygen atoms attached at a specific spot called Y333 by the protein c-Src. (mdanderson.org)
However, in the past few years, some successful structural information was obtained from tiny protein microcrystals grown within living cells, offering exciting new possibilities for proteins that do not form crystals in vitro . (nanowerk.com)
For that they used two different proteins: firefly luciferase and a truncated version of an avian reovirus protein, called muNS, fused to GFP, which allowed them to monitor by fluorescence the initial steps of the crystal formation in the cells. (nanowerk.com)
Rottlerin, isolated from a medicinal plant Mallotus phillippinensis, has been demonstrated to inhibit cellular growth and induce cytoxicity in glioblastoma cell lines through inhibition of calmodulin-dependent protein kinase III. (harvard.edu)
TGF-alpha-containing cells were characterized by double-staining with antibodies to eosinophil cationic protein (ECP). (lu.se)

Conversely, some cells can grow without cell division or without any progression of the cell cycle, such as growth of neurons during axonal pathfinding in nervous system development. (wikipedia.org)
The size of post-mitotic neurons depends on the size of the cell body, axon and dendrites. (wikidoc.org)
GDNF, the glial cell line-derived neurotrophic factor, was originally identified as a survival factor for neurons in the brain. (scienceblog.com)
These cells eventually mature into neurons, the cell type in the brain that controls thought and action. (scripps.edu)
Neurons communicate with each other by secreting messenger chemicals, or neurotransmitters, such as serotonin, which cross the synaptic gulf between cells and bind to receptors on neighboring cell membranes. (biopsychiatry.com)
They are currently examining how embryonic macrophages regulate radial glial cells, the primary source of cortical neurons in early brain development. (nih.gov)

In September 1 Journal of Clinical Investigation , Youyan Zhang and colleagues from Indiana University School of Medicine , Indianapolis, show that normal cells can strongly modulate the growth of mutant populations in vivo and this effect should be taken into account in experiments using only a homogeneous source of tumor-prone cells. (the-scientist.com)
We show that changing the proportion of t(6)A-modified tRNAi (Met), by expression of an un-modifiable tRNAi (Met) or changing the levels of Tcs3, regulate target of rapamycin (TOR) kinase activity and influences cell and animal growth in vivo. (nih.gov)
The anticancer effects of sulforaphane (SFN), which is found in cruciferous vegetables, were studied on KPL-1 human breast cancer cells in vitro and in vivo. (nih.gov)
Cell proliferation in vitro was assessed by a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, and tumor growth and metastasis in vivo were examined in orthotopically (right thoracic mammary fat pad) transplanted KPL-1 cells in female athymic BALB/c mice. (nih.gov)

While previous studies have shown that cranberry extracts inhibit the proliferation of cancer cells, this is the first study to confirm that it's the cranberry PACs that are the active components," said Catherine C. Neto, Ph.D., Associate Professor, Department of Chemistry and Biochemistry at the University of Massachusetts Dartmouth. (news-medical.net)
Disruption of normal regulation of the cell cycle can lead to diseases such as cancer. (medlineplus.gov)
Physicians caring for a patient with clear cell sarcoma of the kidney should consult a pediatric oncologist affiliated with a cancer center that participates in national or international trials to determine the current standard treatment protocol and to determine whether the patient is eligible for an investigational protocol. (medscape.com)
Cancer cells go to great lengths to sustain their growth, survival, and spread. (cancer.gov)
Now scientists believe they have uncovered yet another way in which cancer cells may support their own uncontrolled growth. (cancer.gov)
The discovery emerged from a study of brain cancer cells, which are known to sneak multiple copies of an oncogene into circular pieces of DNA that are separate from chromosomes . (cancer.gov)
In the new NCI-funded study, scientists found that brain cancer cells also slip several different genetic "on switches"-pieces of DNA that help activate genes-into these DNA circles. (cancer.gov)
The findings, published November 27 in Cell , support a different way of thinking about cancer, said Peter Scacheri, Ph.D., of Case Western Reserve University. (cancer.gov)
About 40 years ago, scientists noticed that some cancer cells repeatedly copy and paste -sometimes upwards of 50 times-the same oncogene in their DNA. (cancer.gov)
For example, in an aggressive type of brain cancer called glioblastoma , tumor cells typically have many copies of the EGFR oncogene . (cancer.gov)
Many scientists thought that simply having several copies of an oncogene could cause a cell to become cancerous, explained Ian Fingerman, Ph.D., of the DNA and Chromosome Aberrations Branch in NCI's Division of Cancer Biology , who wasn't involved in the study. (cancer.gov)
It suggests that, over time, certain enhancers may become amplified because they provide an advantage to cancer cells, he added. (cancer.gov)
It's possible that, in DNA circles, contacts between genes and enhancers that normally would have been prevented in the chromosome are driving cancer cell growth via additional boosts to gene expression," Dr. Fingerman noted. (cancer.gov)
Choi's team wanted to see what effect the two compounds have on breast cancer cells. (medindia.net)
Our research shows that although PKM2 plays an important role in cancer metabolism, this enzyme also has an unexpected pivotal function - it regulates cell proliferation directly,' said senior author Zhimin Lu, M.D., Ph.D., associate professor in the Department of Neuro-Oncology at MD Anderson. (mdanderson.org)
Cancer cell metabolism and cancer cell cycle progression, which are essential for tumor formation, are conventionally thought to be regulated primarily by distinct signaling complexes,' Lu said. (mdanderson.org)
The new findings integrate the two major mechanisms for regulating cancer cell growth by a key metabolic enzyme. (mdanderson.org)
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. (cancer.org)
She informed him that the scientific literature is full of "cell-in-cell" references in the context of cancer. (harvard.edu)
and in the setting of non-terminal tumor burden, cytostasis of cancer cells might afford the opportunity for maintaining high quality-of-life and prolongation in survival times. (akcchf.org)
The observation, published in Cell Reports , helps explain why, as people age, the prostate tends to grow, leading to an increased risk for prostate cancer and other conditions. (ucla.edu)
The growth of this market is driven by factors such as the high global prevalence of cancer, growth in stem cell and neurobiology research, and the increasing funding for life sciences research. (seekingalpha.com)
The clinical applications segment is expected to witness higher growth during the forecast period primarily due to the rising prevalence of cancer and the increasing adoption of cell surface markers in cancer treatment. (seekingalpha.com)
They help in the development of new antibodies and specialized cells that help to cure chronic diseases such as cancer. (thebusinessresearchcompany.com)
Renal cell carcinoma (RCC) is the most common form of kidney cancer, with a high recurrence rate and metastasis capacity. (physiciansweekly.com)
TGF-alpha released from these cells could be important for the development of complications seen in ulcerative colitis, such as cancer and fibrosis. (lu.se)
The Laboratory of Cell Biology has a longstanding interest in developing models to study drug resistance mechanisms, including intrinsic and acquired resistance to anti-cancer drugs. (nih.gov)
We found transcriptomic differences in breast and ovarian cancer cell cultures grown in traditional monolayer cultures as compared to cultures grown in the bioreactor in a Matrigel three-dimensional matrix. (nih.gov)
But while folic acid is key to normal cell growth, rapidly dividing cancer cells also have a tremendous appetite for this vitamin. (nih.gov)
Drugs called antifolates have been used for decades in chemotherapy to starve cancer cells of folate, which can help kill the tumor. (nih.gov)
A new study reveals how this escalation occurs in the most common form of kidney cancer: clear cell renal cell carcinoma (ccRCC). (nih.gov)

These act as a hematopoietic growth factor that stimulates the development of granulocytes. (medscape.com)
Spermatagonial stem cells and the hematopoietic stem cells that generate new blood cells are the only types of adult stem cells that can be positively identified using functional assays. (scienceblog.com)
used a Nf1 mutant murine model of juvenile myelomonocytic leukaemia and performed competitive repopulation assays to quantify the proliferative advantage of hematopoietic cells that lack the NF1 tumor-suppressor gene. (the-scientist.com)
Hematopoietic growth factors can often help bring the blood counts closer to normal. (cancer.org)
Hematopoietic growth factors are hormone-like substances that help bone marrow make new blood cells. (cancer.org)

Cell culture media refers to a complex mixture of nutrients, growth factors, salts, vitamins, and other components essential for the in vitro growth, proliferation, and maintenance of cells outside their natural environment. (wytv.com)
Likewise, the ability to culture spermatogonial stem cells indefinitely allows for the possibility to create sperm in vitro, that is, without implanting the stem cells in a recipient male. (scienceblog.com)

Transforming growth factor-beta 1 stimulates vascular smooth muscle cell L-proline transport by inducing system A amino acid transporter 2 (SAT2) gene expression. (mcw.edu)
Transforming growth factor-beta1 (TGF-beta 1) is a multifunctional cytokine that contributes to arterial remodelling by stimulating vascular smooth muscle cell (SMC) growth and collagen synthesis at sites of vascular injury. (mcw.edu)

Other work has suggested that pre-existing cardiomyocytes divide at a fairly low rate to give rise to new cells. (nih.gov)
When cells divide, the [ 15 N] thymidine is taken up and added to new DNA. (nih.gov)
When the cell cycle proceeds without control, cells can divide without order and accumulate genetic errors that can lead to a cancerous tumor . (medlineplus.gov)
Whereas the female germ cell, the egg, stops dividing before birth, the spermatogonial stem cells continue to divide throughout life. (scienceblog.com)
Stem cells must divide, differentiate, migrate and establish connections with post-synaptic targets - a process that takes a few weeks. (biopsychiatry.com)
Vitamin B 9 or folic acid, which is found in dark green leafy vegetables, is essential for cells to grow and divide rapidly-as they do in a growing embryo. (nih.gov)

We investigated the mitogenic effect of basic fibroblast growth factor (FGF), insulin-like growth factor-1 (IGF-1), and epidermal growth factor (EGF), comparing their effects with those of media alone (MEM) in a human skin explant model. (colostrumresearch.org)

The NIH Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative Cell Census Network (BICCN) has unveiled an atlas of cell types and an anatomical neuronal wiring diagram for the mammalian primary motor cortex, derived from detailed studies of mice, monkeys, and humans. (nih.gov)
Dividing heart cells in newborn mice incorporate a tracer that can be seen in the cells' nuclei. (nih.gov)
A study in mice suggests that new heart cells arise from pre-existing heart cells and that the renewal process slows with age. (nih.gov)
A team led by Dr. Richard T. Lee of Brigham and Women's Hospital and Harvard Medical School applied novel technology to investigate heart cell regeneration in mice. (nih.gov)
To study cell turnover at different ages, the scientists gave 3 groups of mice [ 15 N] thymidine for 8 weeks starting at day 4 (newborn), 10 weeks (young adult) or 22 months (old adult). (nih.gov)
To distinguish which types of cells created new cardiomyocytes, they performed similar experiments in mice genetically engineered with fluorescent tags to mark cardiomyocytes. (nih.gov)
These advances, coupled with a recent breakthrough in our ability to transplant these cells into the testes of infertile mice would establish a test system for the assessment of the developmental potential of the cultured and transplanted spermatogenic cells. (nih.gov)
Mice lacking these kidney cells were less well able to suppress UTIs. (nih.gov)
when mice were exposed to UPEC, these cells quickly acidified their urine even further, which appears to be yet another defense against bacterial infection. (nih.gov)
After being kept in culture for three months, the stem cells restored sperm production, and therefore fertility, in infertile mice. (scienceblog.com)
The combination of dasatinib and quercetin was recently shown to prevent cell damage , delay physical dysfunction, and, when used in naturally aging mice, extend their life span. (nih.gov)
When the senescent cells had been eliminated from the mice brains, anxious behavior decreased and new nerve cell growth in the brain was detected. (nih.gov)
The prostates of the older mice were larger and heavier, and had more cells than those of younger mice. (ucla.edu)
While only 6% of luminal prostate cells were progenitors in the younger mice, 21% of luminal cells in older mice were prostate progenitors. (ucla.edu)
Athymic mice received a KPL-1 cell transplant, and SFN treatment (intraperitoneal injection of 25 or 50 mg/kg SFN) was started the next day. (nih.gov)

Previous studies had suggested that several chemical and physical properties of surfaces - including roughness, stiffness and affinity for water - might play a role in stem-cell growth. (medgadget.com)
Dr. Riyaz Hassanali states that growth factors from the PRP create a "healing cascade," encouraging hair growth by helping to repair blood vessels, stimulate collagen, and promote stem cell growth around the hair follicles. (medium.com)
Stem cell assay is developed for studying human stem cell growth to analyze the biological activities of stem cells in a controlled environment. (thebusinessresearchcompany.com)

Fibroblast growth factor 21 (FGF21), a member of the FGF family, was initially identified by Nobuyuki Itoh's group [ 1 ], and its bioactivity was first discovered as a potential regulator of glucose uptake in mouse and human adipocytes [ 2 ]. (hindawi.com)
Signaling pathway studies indicated that FGF21 could bind fibroblast growth factor receptor (FGFR) 1/2 and coreceptor -Klotho after being secreted from tissues [ 3 , 4 ]. (hindawi.com)
Sak JJ, Prystupa A, Kiciński P, Luchowska-Kocot D, Kurys-Denis E, Bis-Wencel H. Leukocyte cell-derived chemotaxin-2 and fibroblast growth factor 21 in alcohol-induced liver cirrhosis. (wjgnet.com)

One particular goal of this initiative is to improve our ability to culture the self-renewable spermatogonial stem cells in order to be able to conduct cause and effect experiments. (nih.gov)
According to Brinster, it is possible to modify the male germ line between generations by manipulating the spermatogonial stem cells in culture. (scienceblog.com)
GDNF was also found to be excreted by the Sertoli cells that surround and support the spermatogonial stem cells in the testes. (scienceblog.com)
The identification of the exogenous factors that allow these stem cells to proliferate in culture establishes the foundation to study the basic biology of spermatogonial stem cells," Kubota said. (scienceblog.com)

In metabolism, PKM2 enhances oxygen-driven processing of sugar known as aerobic glycolysis or the Warburg effect found in tumor cells. (mdanderson.org)
Results were reported in Cell Metabolism . (nih.gov)
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis , Cell Metabolism , Published online January 3, 2019. (nih.gov)
They traced it to a well-known signaling pathway known as mTOR (short for "mammalian target of rapamycin"), which is a central regulator of cell metabolism, growth, proliferation and survival. (scripps.edu)
For example, cells must change their metabolism when nutrients are not available. (nih.gov)

This covalent modification of the molecular structure of Cdc2 inhibits the enzymatic activity of Cdc2 and prevents cell division. (wikidoc.org)

This RFA, Male Germ Cell Growth and Differentiation, is related to the priority area of family planning. (nih.gov)
However, the roles of FGF21 in myogenic differentiation and cell cycle remain obscure. (hindawi.com)
Also, we deduce that FGF21 promotes the initiation of myogenic differentiation mainly through enhancing cell cycle exit of C2C12 cells. (hindawi.com)
Taken together, our results demonstrated that FGF21 promotes cell cycle exit and enhances myogenic differentiation of C2C12 cells. (hindawi.com)
Leukaemia inhibitory factor (LIF) is a cytokine that induces macrophage differentiation of the murine Ml myeloid leukaemia cell line 1,2 . (nature.com)
The demonstration that the differentiation factor LIF will also serve as a growth factor for at least one myeloid leukaemic cell line provides further evidence that the distinction between growth-promoting and differentiation-inducing activities are largely determined by the target cell type. (nature.com)
Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells. (nih.gov)

Tight regulation of this process ensures that a dividing cell's DNA is copied properly, any errors in the DNA are repaired, and each daughter cell receives a full set of chromosomes. (medlineplus.gov)
By controlling oxygen delivery, we observed differences in cell growth morphology and transcriptome regulation under the three conditions. (nih.gov)

They also discovered that levels of beta-catenin phosphorylation and PKM2 in the cell nucleus are correlated with brain tumor malignancy and prognosis and might serve as biomarkers for customized treatment with Src inhibitors. (mdanderson.org)

Improving understanding of how plant cells build cellulose and cell walls could eventually help scientists more easily break it apart for use in biofuels. (sciencedaily.com)
An MIT research team with help from English and Korean scientists have identified a synthetic material that is effective in promoting the growth of pluripotent stem cells on its surface. (medgadget.com)
Using this new technology, scientists should hopefully be able to overcome the challenge of farming enough stem cells for effective research and future therapeutic needs. (medgadget.com)
When the scientists used DNA editing techniques to interfere with each of the switches individually, EGFR gene expression and cell survival dropped. (cancer.gov)
The scientists note that the data show that senescent cells play a role in causing impaired cell growth due to obesity. (nih.gov)
The Stem Cell Interest Group was established to enhance communication and to foster collaboration among scientists from varying disciplines interested in stem cells. (nih.gov)
But in a study involving tadpoles, which develop entirely outside of a mother's womb, scientists at Scripps Research were able to unearth new findings about how brain cells respond to-and recover from-lack of nutrition. (scripps.edu)

The marked reduction of membranous TbetaR-II and their predominant cytoplasmic location diminishes TGF-beta growth inhibition and may contribute to the transformation of VC into the more aggressive SqCC. (nih.gov)

The combination of these 2 events can, in turn, inhibit the growth of neoplastic cells. (medscape.com)

LAS VEGAS, NEVADA, UNITED STATES, November 21, 2023 / EINPresswire.com / -- The Cell Culture Media Market is driven by increasing demand for biopharmaceuticals, rising investments in life sciences research, and advancements in cell-based therapies. (wytv.com)
The Cell Surface Markers Market is valued at an estimated USD 520 million in 2018 and is projected to reach USD 769 million by 2023, growing at a CAGR of. (seekingalpha.com)
The global stem cell assay market size grew from $1.57 billion in 2022 to $1.89 billion in 2023 at a compound annual growth rate (CAGR) of 20.5% . (thebusinessresearchcompany.com)

The key mitotic regulator securin is expressed at low levels in fetal brain compared with adult, and modulates the proliferation of human embryonic neuronal N-Tera2 (NT2) cells. (nih.gov)
In embryonic neuronal NT2 cells, siRNA repression of separase failed to significantly alter cell turnover, whereas repression of securin expression resulted in increased levels of the activated forms of Rad21 and separase, and promoted cell proliferation. (nih.gov)
Thus, Dr. Mukouyama is studying neuronal influences on vascular branching patterns and vascular influences on both neuronal guidance and neural stem cell maintenance. (nih.gov)

CircCSNK1G3 up-regulates miR-181b to promote growth and metastasis via TIMP3-mediated epithelial to mesenchymal transitions in renal cell carcinoma. (physiciansweekly.com)

The Cell Culture Media Market study includes comprehensive analysis of biotechnological market trends, growth factors, and challenges. (wytv.com)
5, 6 ROS formation can be stimulated by mechanical stress, environmental factors, platelet derived growth factor (PDGF), angiotensin II (Ang II), and low density lipoproteins. (bmj.com)
A different model suggests that TSC works downstream of both growth factor signaling and amino acid sensing pathways, meaning it's regulated by growth factors and nutrient sensors. (nih.gov)
The large share of the North American market is attributed to factors such as the increasing number of R&D activities and the growing use of cell surface markers in personalized medicine and drug discovery & development. (seekingalpha.com)
Platelet-rich-plasma is a concentration of platelets many times greater than found in the blood alone, and therefore has a higher concentration of these growth factors. (medium.com)
The Cell-Free DNA (cf-DNA) Testing Market report includes analysis in terms of both quantitative and qualitative data , taking into factors such as Product pricing, Product penetration, Country GDP, movement of parent market & child markets, End application industries, etc. (pharmiweb.com)
Effect of growth factors on cell proliferation and epithelialization in human skin. (colostrumresearch.org)
Recent studies have suggested an important role for growth factors in promoting wound healing. (colostrumresearch.org)
Additionally, commonly used monolayer cell cultures lack the capacity to provide a physiologically relevant environment for cell culture in terms of cell-cell architecture, extracellular matrix composition, and spatiotemporal delivery of key growth factors and small molecules, such as oxygen. (nih.gov)
Patients usually receive growth factors and similar drugs through subcutaneous (under the skin) injections. (cancer.org)
Giving some patients both epoetin and G-CSF (see "White blood cell growth factors") can improve their response to the epoetin. (cancer.org)

Individual genes are generally expressed via transcription into messenger RNA (mRNA) and translation into proteins, and the expression of each gene occurs to various different levels in a cell-type specific fashion (in response to gene regulatory networks). (wikipedia.org)
The cells at top (blue) are stained to reveal their nuclei, while the cells in the middle and bottom are stained for proteins that are known to be present when cells are pluripotent. (medgadget.com)
Some of the key proteins are important for cell adhesion between myocytes and some are involved in adhesion-dependent cell-to-cell signal transduction that allows for a cascade of cell fusion events. (wikidoc.org)
Known as a red blood cell maturation agent , this drug affects TGF-β proteins in the bone marrow. (cancer.org)
TGF-β proteins normally help control how quickly new cells in the bone marrow mature into functioning red blood cells, so that there aren't too many or too few of them in the body. (cancer.org)
By acting on specific TGF-β proteins, luspatercept helps the bone marrow make more healthy, full grown red blood cells. (cancer.org)

Based on application, the cell surface markers market is segmented into research applications and clinical applications. (seekingalpha.com)
On the basis of end user, the cell surface markers market is segmented into academic & research institutes, hospitals & clinical testing laboratories, and pharmaceutical & biotechnology companies. (seekingalpha.com)
The global cell surface markers market is segmented into four major regions, namely, North America, Europe, Asia, and the Rest of the World. (seekingalpha.com)

Cell growth is not to be confused with cell division or the cell cycle, which are distinct processes that can occur alongside cell growth during the process of cell proliferation, where a cell, known as the mother cell, grows and divides to produce two daughter cells. (wikipedia.org)
The overarching goal of the Laboratory of Stem Cell and Neurovascular Research, led by Dr. Yosuke Mukoyama (Yoh‐suke Mukouyama in PubMed), is to uncover the molecular control of the morphologic processes underlying the branching morphogenesis and patterning of the vascular and nervous systems. (nih.gov)

To inhibit cell growth, the global rate of gene expression can be decreased or the global rate of biomolecular degradation can be increased by increasing the rate of autophagy. (wikipedia.org)
Mantle cell lymphoma (MCL) accounts for 5% to 6% of non-Hodgkin lymphomas, which characteristically overexpresses cyclin D1 due to t(11;14)(q13;q32) translocation involving CCND1-IGH gene rearrangement. (medscape.com)
If each parent in a couple carries a similar defective recessive gene for a disease, for example, it should be possible in the future to harvest the male spermatogenic stem cells, correct the gene in culture and implant the stem cells back into the male to produce normal sperm," Brinster said. (scienceblog.com)
These switches also activate EGFR in cells that lack amplification of the gene, they found. (cancer.gov)
Basically, PKM2 contributes directly to gene transcription for cell growth - a finding that was very surprising. (mdanderson.org)

Cell growth occurs when the overall rate of cellular biosynthesis (production of biomolecules or anabolism) is greater than the overall rate of cellular degradation (the destruction of biomolecules via the proteasome, lysosome or autophagy, or catabolism). (wikipedia.org)
Cells can grow by increasing the overall rate of cellular biosynthesis such that production of biomolecules exceeds the overall rate of cellular degradation of biomolecules via the proteasome, lysosome or autophagy. (wikipedia.org)
After 24 hours, 12 percent of MCF7 cells displayed massive cellular and nuclear degradation lacking apoptotic hallmarks. (harvard.edu)
But exactly how early brain growth is affected by nutrition is not as well understood, especially on a cellular level. (scripps.edu)

The ability of TGF-beta 1 to induce SAT2 expression may function to provide SMCs with the necessary levels of l-proline required for collagen synthesis and cell growth. (mcw.edu)

We wanted to know what regulates growth in the cell's length, and found that the story is more complicated than just rings on a barrel. (sciencedaily.com)
The lab found that the Rag GTPase, which was previously thought to function exclusively in amino acid sensing, also regulates the recruitment of TSC to lysosomes in response to growth factor restriction. (nih.gov)

Human spinal cord cell atlas provides foundation to study neurodegeneration, chronic pain, and other diseases. (nih.gov)
Recent research has shown that the human heart generates new cardiomyocytes throughout its lifespan, but how frequently the cells are generated and where they come from is still debated. (nih.gov)
The National Human Genome Research Institute's Talking Glossary provides information about the cell cycle . (medlineplus.gov)
We have isolated a cDNA clone encoding a novel human haemopoietic growth factor, human interleukin for DA cells (HILDA) that supports the proliferation of the murine interleukin-3-dependent leukaemic cell line, DA-la (refs 3-5). (nature.com)
Next, he looked at other human cell lines. (harvard.edu)
Extracellular vesicles from human bone marrow mesenchymal stem cells repair organ damage caused by cadmium poisoning in a medaka model. (karger.com)
The global human embryonic stem cell market reached a value of about USD 0.85 billion in 2022. (expertmarketresearch.com)
North America is a significant regional market in the human embryonic stem cell industry due to the presence of a major number of players and the high incidence of diseases, such as diabetes, heart disease, renal failure, and osteoporosis within the region. (expertmarketresearch.com)
Human embryonic stem cell comes from embryos and are pluripotent and is about 3-5 days old. (expertmarketresearch.com)
The regional markets for human embryonic stem cell can be divided into North America, Europe, the Asia Pacific, Latin America, and the Middle East and Africa. (expertmarketresearch.com)
The demand for newer and better therapies to treat autoimmune, neurological, and cardiovascular diseases has resulted in an increase in research activities and funding for cell-based research, which is expected to favourably aid the growth of the human embryonic stem cell industry. (expertmarketresearch.com)

[ 3 , 4 ] The classic cytology is observed in approximately 88% of cases, and the lymphoma cells are small to medium sized with irregular nuclei, moderately dispersed chromatin, and inconspicuous nucleoli. (medscape.com)
[ 3-5 ] The small cell subtype accounts for only 2% to 4%, which closely resembles small lymphocytic lymphoma with small round or slightly irregular nuclei and condensed chromatin. (medscape.com)
It can then be seen in the cells' nuclei using MIMS. (nih.gov)

We observed that rottlerin significantly inhibited the expression of Cdc20 in glioma cells, implying that Cdc20 could be a novel target of rottlerin. (harvard.edu)

A complex called TORC1 integrates various signals to control cell growth, proliferation, and cell death. (nih.gov)

This study showed us, for the first time in a vertebrate species, the cell signaling pathways that are integral to nutrient-responsive cell division in neural stem cells. (scripps.edu)
Cells use highly coordinated pathways to sense and adapt to their environment. (nih.gov)
The findings support a model in which both the amino acid sensing and growth factor signaling pathways use the Rag GTPase to inhibit TORC1 activity by regulating TSC lysosomal dynamics. (nih.gov)

Overholtzer conducted additional experiments with his non-cancerous cell line. (harvard.edu)
Cancerous MCF7 cells proved particularly prone to invasions with a whopping 30 percent of them housing "neighbors. (harvard.edu)

While the exact mechanism has yet to be determined, evidence from this study suggests that contact with molecules produced by UPEC and/or with the bacteria themselves stimulates these kidney cells both to produce the LCN2 defense molecule and to acidify the urine within hours of infection. (nih.gov)

Discovery of this acute response that effectively targets the most common cause of UTIs expands the role played by the kidney in innate defense against such infections, and could also provide new insight into why diseases that damage the kidney's alpha-intercalated cells leave patients more susceptible to UTIs. (nih.gov)
Several key findings support the concept that ROS contribute to vascular diseases through effects on vascular smooth muscle cells (VSMC). (bmj.com)
Additionally, the Food & Drug Administration (FDA) has approved clinical trials, which indicated the advantageous use of stem cells in treating such diseases. (expertmarketresearch.com)
The primary objective of stem cell therapy is to assist doctors in the treatment of neurodegenerative diseases, diabetes, and heart disease. (expertmarketresearch.com)
The rising prevalence of cardiac and malignant diseases around the world is expected to have a significant impact on demand and is anticipated to accelerate the market growth. (expertmarketresearch.com)
The high prevalence of chronic diseases is expected to propel the growth of the stem cell assay market going forward. (thebusinessresearchcompany.com)
Stem cells have the potential to treat a wide range of diseases, including chronic diseases. (thebusinessresearchcompany.com)
Therefore, the increase in the prevalence of chronic diseases is driving the growth of the stem cell assay market. (thebusinessresearchcompany.com)

Under the influence of certain plant hormones the cell wall can be remodeled, allowing for increases in cell size that are important for the growth of some plant tissues. (wikidoc.org)
Clearing senescent cells from the brain and other tissues can delay, prevent, or alleviate multiple age-related disorders. (nih.gov)

The large size of some eggs can be achieved either by pumping in cytosolic components from adjacent cells through cytoplasmic bridges named ring canals (Drosophila) or by internalisation of nutrient storage granules (yolk granules) by endocytosis (frogs). (wikipedia.org)
It is known that LCN2 can arrest the growth of E. coli and certain other bacteria by limiting their access to the essential nutrient iron. (nih.gov)
If the nutrient supply is restricted (after time t = 2 in the diagram, below) and the rate of increase in cell size is slowed, the time period between cell divisions is increased. (wikidoc.org)
Nutrient availability influences mTOR so that when cells are not able to grow to normal size they will not undergo cell division. (wikidoc.org)

This is because a single cell with only one copy of the genome in the cell nucleus can perform biosynthesis and thus undergo cell growth at only half the rate of two cells. (wikipedia.org)

Platelet-rich plasma, or PRP for short, restores hair growth through injections of a patient's own platelets into their scalp. (medium.com)

This system also would provide the opportunity to study ways to genetically alter male germ cells such that these alterations can be passed on to the next generation through mature sperm and fertilization. (nih.gov)

When plant cells grow, they tend to expand considerably along their length while not increasing much in width," said Ying Gu, associate professor of biochemistry and molecular biology and co-funded faculty member in the Institutes of Energy and the Environment at Penn State and lead author of the study. (sciencedaily.com)
The term cell growth is used in two different ways in biology . (wikidoc.org)
Hiroshi Kubota, a research assistant professor of cell biology at the Penn Veterinary school, developed the serum-free culture system that enabled him, along with Brinster and researcher Mary R. Avabock, to discover the essential ingredients that will sustain these cells. (scienceblog.com)
Topics of interest include fundamental stem cell biology, ontogeny, gerontology, and the therapeutic potential of stem cells. (nih.gov)
We're not sure if entosis evolved to play a particular role or if it's simply an aberration of a normal process," adds Brugge, who is Chair of the Department of Cell Biology. (harvard.edu)
In collaboration with Guillaume Normand of Associate Professor of Cell Biology Randall King's lab, he tracked the cells over time and was shocked to see that some of them actively bored into their neighbors. (harvard.edu)
This research has been coordinated by Prof. Lars L. Redecke (Center for Structural and Cell Biology in Medicine, University of Lübeck, Germany), in collaboration with the CiQUS (University of Santiago de Compostela, Spain), the Interfaculty Institute of Biochemistry (University of Tübingen, Germany) and the Institute of Biochemistry and Molecular Biology (University of Hamburg). (nanowerk.com)
Understanding what's causing the prostate to grow with age helps us to consider strategies to prevent the expansion of these cells and possibly reduce a person's risk for prostate growth or disease," said Andrew Goldstein, member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA and a UCLA assistant professor of urology and of molecular, cell, and developmental biology. (ucla.edu)

These findings may lead to new approaches for starting and stopping cell growth in the brain. (scripps.edu)
McKeown said the findings also will contribute to ongoing research on the role of neural stem cells in recovery from brain injury . (scripps.edu)
Our findings indicted that rottlerin could exert its tumor suppressive function by inhibiting Cdc20 pathway which is constitutively active in glioma cells. (harvard.edu)

After periods without food, nutrition induces widespread proliferation of neural stem cells (green) in the tadpole brain. (scripps.edu)
Typically, in a Xenopus tadpole and in most animals, stem cells known as "neural progenitors" flourish during early stages of development. (scripps.edu)
The vasculature component of this specialized niche microenvironment helps to retain neural stem cell potential. (nih.gov)

We've demonstrated that a central signaling process allows spermatagonial stem cells to continually renew themselves, essentially becoming immortal," said Ralph L. Brinster, a professor of reproductive physiology at Penn. (scienceblog.com)
Insulin is a hormone that allows cells to use sugars from food as energy and can activate mTOR signaling. (scripps.edu)
This investigation explores extracellular glutamate efflux and metabotropic glutamate signaling in sustaining cHSA cell proliferation. (akcchf.org)
One model suggests that TSC works exclusively downstream of a growth factor signaling pathway called PI3K-AKT. (nih.gov)

This study discussed the effect of extracellular vesicles (EVs) released from bone marrow mesenchymal stem cells (BMSCs) on ALL cells and the mechanism. (karger.com)
Cell viability and cell toxicity assays are used to assess the physical and physiological well-being of cells in response to extracellular stimuli, chemical agents, medicinal treatments, or other situations, as well as when deciding on the best conditions for cell culture growth. (thebusinessresearchcompany.com)

The team next used MIMS to study cell turnover following a heart attack. (nih.gov)
Plant cells tend to grow longer instead of wider due to the alignment of the many layers of cellulose that make up their cell walls, according to a new study that may have implications for biofuels research. (sciencedaily.com)
At a time when the global economy is experiencing major disruption in healthcare, Global Market Studies' latest report offers invaluable insights into the key opportunities and challenges that the Cell Culture Media Market offers and can expect to tackle over the study forecast period up to 2028. (wytv.com)
In this study, we investigated the function of FGF21 in myogenesis and cell cycle exit using C2C12 cell line. (hindawi.com)
They also conclude that this study provides proof of concept that senescent cells contribute to obesity-induced anxiety and that senolytics may offer a potential new way for treating neuropsychiatric disorders. (nih.gov)
With tadpoles, we can look at early stages of brain development that are typically inaccessible to us," says cell biologist Caroline McKeown, PhD, a senior staff scientist in the neuroscience lab of Hollis Cline, PhD , and lead author of the study. (scripps.edu)
SIGNIFICANCE AND IMPACT OF THE STUDY: Our results indicate that the cell wall structure is merely determined by cross-linking between cell wall polymers, pointed out the role of beta-1,6-glucan in this process. (unboundmedicine.com)
It incorporates market evolution study, involving the current scenario, growth rate, and capacity inflation prospects, based on Porter's Five Forces and DROT analyses. (pharmiweb.com)
To study the intracellular location of transforming growth factor beta type II receptors (TbetaR-II) in verrucous carcinoma (VC) and squamous cell carcinoma (SqCC), and to evaluate their role in the biological behavior of both neoplasias. (nih.gov)

The dynamics of cell- wall construction are incompletely understood, in part because of limitations in current techniques for observing peptidoglycan synthesis. (acs.org)
The compounds label peptidoglycans at sites of peptidoglycan synthesis in bacteria, and their fluorescence can be observed in the microbes' newly synthesized cell walls. (acs.org)
Different colors can be applied to the bacteria sequentially to monitor sites of peptidoglycan synthesis over time and obtain time-dependent images of cell-wall growth. (acs.org)
Second, they need to coordinate synthesis and breakdown of cell wall components to maintain integrity throughout division. (harvard.edu)
Yeast lacking central components of the t(6)A synthesis machinery, such as Tcs3p (Kae1p) or Tcs5p (Bud32p), show slow-growth phenotypes. (nih.gov)

In Wee1 mutants, there is less Wee1 activity and Cdc2 becomes active in smaller cells, causing cell division before the yeast cells reach their normal size. (wikidoc.org)
While no obvious correlation could be found between beta-glucan or mannan levels and the susceptibility of whole yeast cells to zymolyase, increase of beta-1,6-glucan levels, albeit modest with respect to the growth conditions investigated, and to a lesser extent that of chitin, was associated with decreased sensitivity of yeast cells to the lytic action by zymolyase. (unboundmedicine.com)

Glioblastoma cells have x-shaped chromosomes (blue) with areas where the oncogene EGFR is normally found (green), but also circular pieces of DNA (red) with many additional copies of EGFR . (cancer.gov)
Moreover, the switches appeared to be vital to glioblastoma cells. (cancer.gov)
In some glioblastoma cells, there were more copies of on switches than copies of EGFR . (cancer.gov)

How do genes control the growth and division of cells? (medlineplus.gov)
A variety of genes are involved in the control of cell growth and division. (medlineplus.gov)
The cell cycle has checkpoints (also called restriction points), which allow certain genes to check for problems and halt the cycle for repairs if something goes wrong. (medlineplus.gov)
Genetic studies of the fruit fly Drosophila have revealed several genes that are required for the formation of multinucleated muscle cells by fusion of myoblasts [3] . (wikidoc.org)
Our data showed that the expression of myogenic genes as well as cell cycle exit genes was increased after FGF21 overexpression, and FGF21 overexpression induces cell cycle arrest. (hindawi.com)
Moreover, cell cycle genes were decreased in FGF21 overexpression cells while they were increased in FGF21 knockdown cells. (hindawi.com)

A new technique that incorporates fluorescently labeled d -amino acids into bacteria makes it possible to observe biosynthesis of peptidoglycans, the major component of cell walls, in real time. (acs.org)

Sickled cells can block blood flow in blood vessels that provide blood to bones in our body. (cdc.gov)
This swelling, often along with a fever, is caused by the sickled cells getting stuck in the blood vessels and blocking blood flow in the small bones of the hands and feet. (cdc.gov)

Once added to the culture, GDNF caused the stem cells to form dense clusters and proliferate continuously. (scienceblog.com)

Hence, two cells grow (accumulate mass) at twice the rate of a single cell, and four cells grow at 4-times the rate of a single cell. (wikipedia.org)
Some special cells can grow to very large sizes via an unusual endoreplication cell cycle in which the genome is replicated during S-phase but there is no subsequent mitosis (M-phase) or cell division (cytokinesis). (wikipedia.org)
[ 3 ] Mantle zone growth is observed as the predominant pattern in less than 2% of MCL cases, in which the lymphoma cells grow in the mantles around preexisting germinal centers. (medscape.com)
The market size of global stem cell assay market is expected to grow to $4 billion in 2027 at a CAGR of 20.6% . (thebusinessresearchcompany.com)

Organisms1

Chemicals and Drugs1

Phenomena and Processes4

Information Science1

Embryonic stem5

Tumors17

Tumor cell growth3

Apoptosis18

Causing cell proliferation1

Tissue16

Researchers24

Progenitor15

Protein19

Neurons6

Vivo4

Cancer31

Hematopoietic5

Vitro2

Vascular smooth musc2

Divide6

Epidermal growth1

Mice15

Stem-cell growth3

Fibroblast3

Spermatogonial stem cells4

Metabolism5

Inhibits1

Differentiation7

Regulation2

Brain tumor1

Scientists7

Inhibition1

Inhibit the growth1

20233

Neuronal3

Renal cell carc1

Factors11

Proteins6

Market is segmented3

Processes2

Gene5

Cellular4

Collagen1

Regulates2

Human11

Nuclei3

Significantly inhibited1

Signals1

Pathways3

Cancerous2

Stimulates1

Diseases8

Tissues2

Nutrient4

Undergo1

Restores1

Genetically1

Biology8

Findings3

Neural3

Signaling4

Extracellular2

Study9

Synthesis5

Yeast cells2

Glioblastoma3

Genes6

Component of cell walls1

Blood vessels2

Proliferate1

Grow4