The identification of this second cell population helps differentiate MNTI from other small, round, blue cell tumors. (medscape.com)
While most tumors metastatic to the serous membranes are of epithelial origin, cytologists should be aware that non-epithelial neoplasms can also cause malignant effusions including sarcomas, melanomas, germ cell tumors, and, more rarely, brain tumors. (cytojournal.com)
The differential diagnosis of a malignant effusion is accordingly broad, especially for the small round blue cell tumors that includes not only mesenchymal tumors, but also non-mesenchymal tumors, such as neuroblastoma and Wilms tumor. (cytojournal.com)
Common non-epithelial neoplasms that may cause malignant effusions include malignant melanoma, sarcomas, and other neoplasms including germ cell tumors [ Figure 1 ]. (cytojournal.com)
Neuroblastoma2
The histologic appearance of MNTI is usually that of a small, dark, cell neoplasm suggestive of neuroblastoma, rhabdomyosarcoma, Ewing sarcoma, lymphoma, desmoplastic small round cell tumor, and peripheral primitive neuroectodermal tumor. (medscape.com)
Other rare non-epithelial malignancies that may be encountered in effusion cytology include neuroblastoma, Wilms tumor, and metastatic brain tumors. (cytojournal.com)
Differential diagnosis1
Consider clinical, radiographic, laboratory, and histologic findings when establishing a proper differential diagnosis for melanotic neuroectodermal tumor of infancy (MNTI). (medscape.com)
Metastatic1
Most tumors metastatic to the serous membranes are of epithelial origin. (cytojournal.com)
Infancy3
Neville B, Damm D, Allen C. Melanotic Neuroectodermal Tumor of Infancy. (medscape.com)
Melanotic neuroectodermal tumor of infancy--a neoplasm of neural crese origin. (medscape.com)
Cutler LS, Chaudhry AP, Topazian R. Melanotic neuroectodermal tumor of infancy: an ultrastructural study, literature review, and reevaluation. (medscape.com)
Ewing sarcoma tumors usually form in the hip bones, the ribs, or in the middle of long bones. (dana-farber.org)
Ewing tumors are most common in bone but can also form in soft tissue. (dana-farber.org)
Epithelial3
The same age differential is noted with respect to the more common odontogenic tumors (eg, ameloblastoma, odontoma, adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, ameloblastic fibroma, odontogenic myxoma, odontogenic fibroma). (medscape.com)
Diagnosing non-epithelial malignancies in effusion specimens based entirely upon their cytomorphologic features is difficult because these neoplasms often exhibit considerable morphological overlap and their cytomorphology can differ from the original tumor. (cytojournal.com)
The classification of epithelial tumors of the kidney has in particular undergone substantial progress in the last two decades with major contributions from genetic typing of renal cell carcinomas (RCCs). (abdominalkey.com)
Small2
adenomatoid t. a small benign t. of the male epididymis and female genital tract , consisting of fibrous tissue or smooth muscle enclosing anastomosing glandlike spaces containing acid mucopolysaccharide lined by flattened cells that have ultra-structural characteristics of mesothelial cells. (en-academic.com)
neoplastic cells are frequently palisaded at the periphery of the small groups, and the latter have a tendency to infiltrate surrounding tissue . (en-academic.com)
Clinical1
Our group is also dedicated to clinical research to develop innovative treatment strategies for soft tissue and bone malignancies. (dana-farber.org)
Sections1
Specific discussions of etiology and pathogenesis are dealt with in each of the sections on individual tumors, rather than as a freestanding section, as is used elsewhere in this text. (abdominalkey.com)
Syndrome3
Blau syndrome Chronic infantile neurologic cutaneous and articular syndrome Familial cold urticaria (familial cold autoinflammatory syndrome) Familial Mediterranean fever Hyper-IgD syndrome Majeed syndrome Muckle-Wells syndrome TNF receptor associated periodic syndrome (familial Hibernian fever, TRAPS, tumor necrosis factor receptor associated periodic syndrome) Chronic blistering cutaneous conditions have a prolonged course and present with vesicles and bullae. (wikipedia.org)
Patients with Beckwith-Wiedemann syndrome and Denys-Drash syndrome have an increased risk of developing Wilms tumor ( 5 , 6 ). (abdominalkey.com)
Wiedemann-Beckwith syndrome is related to abnormalities on chromosome 11p15 and characterized by multiple craniofacial anomalies, abdominal wall defects, and tumors of the genitourinary tract, liver, adrenal gland, and central nervous system among other abnormalities. (abdominalkey.com)
Population1
The first section will cover those tumors that characteristically are associated with the pediatric population. (abdominalkey.com)
1 - 3 Intracranial brain tumors, most commonly medulloblastoma [ Figure 2 ], can metastasize to the peritoneal cavity via ventriculo-peritoneal shunts used to divert excess cerebrospinal fluid. (cytojournal.com)
Types1
The purpose of this chapter is to familiarize the reader with the tumor types encountered in the human rather than to provide a comprehensive diagnostic reference, which is better handled in more comprehensive textbooks and monographs. (abdominalkey.com)
Human1
A diverse array of tumors can arise in the human kidney. (abdominalkey.com)