Grb2 functional tyrosine kinase domain src homology 3 domain. Medical search. Frequent questions

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Anatomy17

Cell Line 3T3 Cells Cells, Cultured Tumor Cells, Cultured Cell Line, Tumor COS Cells Cell Membrane HeLa Cells Cytoplasm CHO Cells Jurkat Cells Fibroblasts Cell Nucleus Cell Line, Transformed NIH 3T3 Cells HEK293 Cells PC12 Cells

Organisms7

Cricetinae Escherichia coli Cercopithecus aethiops Saccharomyces cerevisiae Mice, Knockout Cattle Mice, Inbred C57BL

Diseases5

Pain Insensitivity, Congenital Cell Transformation, Neoplastic Hypohidrosis Leukemia, Myelogenous, Chronic, BCR-ABL Positive Lung Neoplasms

Chemicals and Drugs142

Tyrosine Protein-Tyrosine Kinases GRB2 Adaptor Protein Receptor Protein-Tyrosine Kinases GRB10 Adaptor Protein src-Family Kinases Phosphotyrosine Receptor, Epidermal Growth Factor Protein Kinase Inhibitors Proto-Oncogene Proteins Phosphatidylinositol 3-Kinases Recombinant Fusion Proteins GRB7 Adaptor Protein Adaptor Proteins, Signal Transducing Protein Tyrosine Phosphatases Proto-Oncogene Proteins c-abl Protein Kinases Protein-Serine-Threonine Kinases Proto-Oncogene Proteins pp60(c-src)Phosphoproteins Recombinant Proteins Intracellular Signaling Peptides and Proteins Pyrimidines Receptor, Insulin fms-Like Tyrosine Kinase 3 Protein Tyrosine Phosphatase, Non-Receptor Type 11 Proteins Calcium-Calmodulin-Dependent Protein Kinases Protein Tyrosine Phosphatase, Non-Receptor Type 6 Proto-Oncogene Proteins c-fyn Lymphocyte Specific Protein Tyrosine Kinase p56(lck)DNA, Complementary DNA-Binding Proteins Benzamides Proto-Oncogene Proteins c-kit DNA Primers Membrane Proteins Enzyme Inhibitors Piperazines RNA, Messenger Carrier Proteins Janus Kinase 2 Quinazolines Ligands Proto-Oncogene Proteins c-ret Protein Kinase C Phospholipase C gamma DNA Proto-Oncogene Proteins c-met Mitogen-Activated Protein Kinases Receptor, trkA Receptors, Fibroblast Growth Factor Mitogen-Activated Protein Kinase 1 Fusion Proteins, bcr-abl Epidermal Growth Factor Shc Signaling Adaptor Proteins Focal Adhesion Protein-Tyrosine Kinases Genistein Receptor, Fibroblast Growth Factor, Type 5 SH2 Domain-Containing Protein Tyrosine Phosphatases Focal Adhesion Kinase 2 Focal Adhesion Kinase 1 Isoenzymes Antineoplastic Agents Glutathione Transferase Transcription Factors Tyrosine 3-Monooxygenase Mitogen-Activated Protein Kinase 3 Receptors, Platelet-Derived Growth Factor Receptor, Fibroblast Growth Factor, Type 1 Cyclic AMP-Dependent Protein Kinases Drosophila Proteins Trans-Activators Peptides Phosphotransferases (Alcohol Group Acceptor)Peptide Fragments Proto-Oncogene Proteins c-crk Mitogen-Activated Protein Kinase Kinases Type C Phospholipases p38 Mitogen-Activated Protein Kinases Oncogene Protein pp60(v-src)Adaptor Proteins, Vesicular Transport JNK Mitogen-Activated Protein Kinases p21-Activated Kinases Nuclear Proteins Receptors, Cell Surface STAT5 Transcription Factor Phosphopeptides Milk Proteins Vanadates Proto-Oncogene Proteins c-akt Serine Proto-Oncogene Proteins c-cbl Calcium Extracellular Signal-Regulated MAP Kinases Receptors, Growth Factor Proto-Oncogene Proteins c-hck Nerve Tissue Proteins Cytoskeletal Proteins MAP Kinase Kinase Kinases Receptor, erbB-2 Receptors, Nerve Growth Factor Tyrphostins Enzyme Precursors Proline Bacterial Proteins Phosphoric Monoester Hydrolases ZAP-70 Protein-Tyrosine Kinase Oncogene Proteins Protein Isoforms Cell Cycle Proteins Oncogene Proteins v-abl Ribosomal Protein S6 Kinases Actins Quinones Nerve Growth Factors Son of Sevenless Proteins Cyclin-Dependent Kinases Lactams, Macrocyclic Nucleoside-Phosphate Kinase GTPase-Activating Proteins Indoles Receptor, IGF Type 1 Macromolecular Substances Benzoquinones CDC2 Protein Kinase Threonine MAP Kinase Kinase 1 Adenosine Triphosphate Guanylate Kinase Proto-Oncogene Proteins c-yes RNA, Small Interfering Receptors, Antigen, B-Cell Receptors, Antigen, T-Cell Proto-Oncogene Proteins c-vav Microfilament Proteins Protein Tyrosine Phosphatase, Non-Receptor Type 1 Oncogene Proteins, Fusion eIF-2 Kinase ras GTPase-Activating Proteins Cell Adhesion Molecules Antibodies, Monoclonal

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Transfection Cloning, Molecular Sequence Alignment Mutagenesis, Site-Directed Models, Molecular Crystallography, X-Ray Precipitin Tests Blotting, Western DNA Mutational Analysis Immunoblotting Amino Acid Substitution Two-Hybrid System Techniques Models, Biological Polymerase Chain Reaction Electrophoresis, Polyacrylamide Gel Immunoprecipitation Peptide Mapping Microscopy, Fluorescence Immunohistochemistry

Phenomena and Processes62

src Homology Domains Phosphorylation Signal Transduction Amino Acid Sequence Sequence Homology, Amino Acid Mutation Protein Binding Base Sequence Protein Structure, Tertiary Binding Sites Enzyme Activation Transfection MAP Kinase Signaling System Protein Conformation Kinetics Structure-Activity Relationship Amino Acid Motifs Point Mutation Sequence Deletion Protein Interaction Domains and Motifs Dimerization Sequence Homology, Nucleic Acid Amino Acid Substitution Protein Structure, Secondary Cell Division Gene Expression Mutation, Missense Genes, erbB-1 Conserved Sequence Genes, src Protein Transport Substrate Specificity Exons Mutagenesis Transcription, Genetic Drug Resistance, Neoplasm Plasmids Apoptosis Gene Expression Regulation Phenotype Cell Adhesion Proto-Oncogenes Protein Processing, Post-Translational Time Factors Cell Movement Dose-Response Relationship, Drug Catalysis Molecular Weight Cell Proliferation Down-Regulation Oncogenes PDZ Domains Gene Expression Regulation, Enzymologic Structural Homology, Protein Protein Multimerization Cell Differentiation Catalytic Domain Transcriptional Activation Protein Structure, Quaternary Promoter Regions, Genetic Cell Survival Protein Folding

Disciplines and Occupations1

Immunohistochemistry

Technology, Industry, Agriculture1

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Technology, Industry, Agriculture Information Science

src Homology Domains Tyrosine Protein-Tyrosine Kinases GRB2 Adaptor Protein Phosphorylation Receptor Protein-Tyrosine Kinases Molecular Sequence Data Signal Transduction Amino Acid Sequence Sequence Homology, Amino Acid GRB10 Adaptor Protein src-Family Kinases Phosphotyrosine Mutation Protein Binding Receptor, Epidermal Growth Factor Protein Kinase Inhibitors Base Sequence Proto-Oncogene Proteins Phosphatidylinositol 3-Kinases Recombinant Fusion Proteins Protein Structure, Tertiary GRB7 Adaptor Protein Binding Sites Adaptor Proteins, Signal Transducing Enzyme Activation Cell Line Protein Tyrosine Phosphatases Transfection Cloning, Molecular Proto-Oncogene Proteins c-abl Protein Kinases Protein-Serine-Threonine Kinases Proto-Oncogene Proteins pp60(c-src)Phosphoproteins Recombinant Proteins 3T3 Cells Sequence Alignment Intracellular Signaling Peptides and Proteins MAP Kinase Signaling System Mutagenesis, Site-Directed Models, Molecular Pyrimidines Receptor, Insulin fms-Like Tyrosine Kinase 3 Protein Tyrosine Phosphatase, Non-Receptor Type 11 Protein Conformation Kinetics Proteins Calcium-Calmodulin-Dependent Protein Kinases Cells, Cultured Protein Tyrosine Phosphatase, Non-Receptor Type 6 Crystallography, X-Ray Proto-Oncogene Proteins c-fyn Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Structure-Activity Relationship DNA, Complementary Amino Acid Motifs Point Mutation DNA-Binding Proteins Benzamides Sequence Deletion Protein Interaction Domains and Motifs Proto-Oncogene Proteins c-kit DNA Primers Membrane Proteins Enzyme Inhibitors Precipitin Tests Blotting, Western Piperazines Dimerization RNA, Messenger Carrier Proteins DNA Mutational Analysis Pain Insensitivity, Congenital Janus Kinase 2 Quinazolines Sequence Homology, Nucleic Acid Ligands Proto-Oncogene Proteins c-ret Immunoblotting Tumor Cells, Cultured Cell Line, Tumor Protein Kinase C Amino Acid Substitution Phospholipase C gamma DNA Proto-Oncogene Proteins c-met Mitogen-Activated Protein Kinases Receptor, trkA Receptors, Fibroblast Growth Factor Mitogen-Activated Protein Kinase 1 Fusion Proteins, bcr-abl Protein Structure, Secondary COS Cells Cell Membrane Epidermal Growth Factor Cell Division Shc Signaling Adaptor Proteins Cell Transformation, Neoplastic

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