EchinococcusCystsZoonotic infectionMultilocularisEndemic2023ParasitesElisa echinococcosisPolycysticDiagnosisAlbendazoleZoonosisParasitic diseaseLiver2018HepaticSpecies2020HumansGenotypeLesionsEpidemiologicalPercutaneousProtoscolicesInfection causedIndirectIntermediate hostsAdultGeneTherapeuticClinical practiceSheepMolecularTreatmentPrimary
Echinococcus31
- Echinococcosis is a parasitic disease caused by tapeworms of the Echinococcus type. (wikipedia.org)
- The main human echinococcal infections are caused by Echinococcus granulosus sensu lato, which causes cystic echinococcosis (CE), and E. multilocularis , which causes alveolar echinococcosis (AE). (cdc.gov)
- A recent consensus on the terminology in the field of echinococcosis has fixed the names of the diseases, the various species of Echinococcus involved and several terms to be used in the scientific literature on the subject. (medscape.com)
- The diagnosis of alveolar echinococcosis relies on imaging and may be confirmed with specific serology and/or molecular identification of the parasite Echinococcus multilocularis in the lesions. (medscape.com)
- Echinococcosis is an infection caused by either the Echinococcus granulosus or Echinococcus multilocularis tapeworm. (medlineplus.gov)
- Echinococcosis is a worldwide anthropozoonosis which is caused by Echinococcus granulosus [ 1 ]. (hindawi.com)
- As estimated, approximately one percent of the farmer population in these areas was infected by Echinococcus granulosus . (hindawi.com)
- Furthermore, it has been reported that Echinococcus granulosus protoscolices have developed resistance to albendazole [ 4 - 6 ]. (hindawi.com)
- Imported hepatopulmonary echinococcosis: first report of Echinococcus granulosus sensu stricto (G1) in Bolivia. (medindia.net)
- A retrospective chart review conducted at two teaching hospitals in Los Angeles County identified 28 patients with infection due to Echinococcus granulosus diagnosed by positive echinococcal serology and/or tissue biopsy between January 1981 and December 1990. (ajtmh.org)
- Az előbbit az Echinococcus granulosus , az ut bbit az Echinococcus multilocularis nevű galandf reg l rv i okozz k. (oek.hu)
- Az Echinococcus granulosus galandf reg felnőtt, ivar rett form ja a vadon lő s a h zi kutyaf l k bel ben lősk dik. (oek.hu)
- Les échantillons sanguins prélevés sur 3446 sujets appartenant à 700 familles sélectionnées au hasard ont été examinés afin de détecter l'anticorps dirigé contre Echinococcus granulosus. (who.int)
- We describe the spatial distribution of Echinococcus multilocularis in its main definitive host, the red fox, and the distribution of human cases of alveolar echinococcosis (AE) within a highly endemic focus in southern Germany (13.7-19.9/100,000 in 1992-2018). (biomedcentral.com)
- The species Echinococcus granulosus, Echinococcus ortleppi, Echinococcus canadensis and Echinococcus intermedius are the causative agents of CE with a worldwide distribution and a highly variable human disease burden in the different endemic areas depending upon human behavioural risk factors, the diversity and ecology of animal host assemblages and the genetic diversity within Echinococcus species which differ in their zoonotic potential and pathogenicity. (uzh.ch)
- Currently, four species are recognized within the genus Echinococcus: E. granulosus (which causes cystic disease), E. multilocularis (which causes alveolar disease), E. vogeli (which causes polycystic disease), and E. oligarthrus (which causes polycystic disease). (med-chem.com)
- Echinococcosis is a parasitic disease of tapeworms of the Echinococcus type characterized by production of unilocular or multilocular cystic disease of lung and liver. (capsulehealth.one)
- The adult Echinococcus granulosus (3 to 6 mm long) [1] resides in the small bowel of the definitive hosts (dogs or other carnivores). (capsulehealth.one)
- Echinococcosis Phylum - Platyhelminthes Class - Cestoda Genus - Echinococcus Species - E. granulosus Echinococcosis is a parasitic disease caused by infection with tiny tapeworms. (thesciencenotes.com)
- Cystic echinococcosis is a zoonotic infection caused by Echinococcus granulosus . (biomedcentral.com)
- El agente causante es el céstodo Echinococcus granulosus, cuyo estadio adulto se desarrolla en el intestino delgado de hospederos definitivos (caninos) y el desarrollo del estadio larval se presenta principalmente en el hígado y pulmón de hospederos intermediarios como el ganado ovino. (edu.pe)
- The causative agent is the tapeworm Echinococcus granulosus, whose adult stage takes place in the small intestine of definitive hosts (dogs) and the development of the larval stage occurs mainly in the liver and lung of intermediate hosts such as sheep. (edu.pe)
- Solitary echinococcus cysts were found in 97 (27%) patients, multiple hepatic echinococcosis found in 262 (73%) patients. (nls-diagnostic.org)
- The aim of this study was for the molecular analysis of Echinococcus granulosus isolates from different regions of Turkey. (bezmialem.edu.tr)
- Hydatid disease is a zoonotic infection caused by Echinococcus granulosus or rarely by Echinococcus multilocularis . (panafrican-med-journal.com)
- Echinococcus granulosus, the etiologic agent of echinococcosis, is among the most essential zoonotic helminthes worldwide. (microarrayworld.com)
- methylcarbamates derivatives (BZD) were proved to be effective against E. granulosus , and since Cystic echinococcosis (CE) caused by the then, many investigators have used albendazole metacestode (larval) stage of Echinococcus (ABZ) and mebendazole (MBZ) for the treatment granulosus ( E. granulosus ) is still an important of human hydatidosis (Teggi et al 1993). (medicpdf.com)
- Whole genomic DNA was extracted from every pattern and amplified for the presence of polymorphism within the mitochondrial cox1 gene of Echinococcus granulosus utilizing a excessive decision melting curve (HRM) methodology. (floatingharborsyndrome.co.uk)
- Human cystic echinococcosis, an endemic zoonosis in Algeria, is caused by larvae of the cestode Echinococcus granulosus. (ac.be)
- Echinococcus granulosus is the most frequent form of echinococcal infection in humans. (bvsalud.org)
- NT005 trade name] is indicated for the treatment of Echinococcus multilocularis and E. granulosus infections before or after surgery or where surgery is not suitable. (who.int)
Cysts9
- These slow-growing masses, often called cysts, are also found in people that are infected with alveolar and polycystic echinococcosis. (wikipedia.org)
- The cysts found in those with cystic echinococcosis are usually filled with a clear fluid called hydatid fluid, are spherical, and typically consist of one compartment and are usually only found in one area of the body. (wikipedia.org)
- While the cysts found in those with alveolar and polycystic echinococcosis are similar to those found in those with cystic echinococcosis, the alveolar and polycystic echinococcosis cysts usually have multiple compartments and have infiltrative as opposed to expansive growth. (wikipedia.org)
- Most often, echinococcosis cysts do not cause symptoms and are found when an imaging test is done for another reason. (medlineplus.gov)
- Primary multiple temporal cystic lesion, minimally en- human infection are E. granulosus and cerebral hydatid cysts are quite unu- hanced after contrast. (who.int)
- Brain cysts caused by E. granulosus rupture [6,7,10]. (who.int)
- Molecular analysis showed that all of the human cysts belonged to the G1 genotype (common sheep strain) of E. granulosus. (bezmialem.edu.tr)
- as an aid in the surgical treatment of echinococcosis cysts. (bestpharmbuy.com)
- Ovarian echinococcosis should always be kept in mind such as a differential diagnosis with ovarian cysts and malignancies. (panafrican-med-journal.com)
Zoonotic infection2
- Human echinococcosis is a zoonotic infection (i.e it is a disease of animal kingdom that sometimes can be transmitted to humans). (medindia.net)
- Cystic echinococcosis is a worldwide zoonotic infection that triggers significant economic losses in animals. (researchgate.net)
Multilocularis2
- In the human manifestation of the disease, E. granulosus, E. multilocularis, E. oligarthrus and E. vogeli are localized in the liver (in 75% of cases), the lungs (in 5-15% of cases) and other organs in the body such as the spleen, brain, heart, and kidneys (in 10-20% of cases). (wikipedia.org)
- Infection with the larval form of E multilocularis causes alveolar echinococcosis (AE). (medscape.com)
Endemic1
- Echinococcosis is a worldwide anthropozoonosis which is highly endemic over large animal husbandry areas in northwestern China. (hindawi.com)
20231
- In September 2023, a patient in Italy who had never traveled abroad was referred for testing for suspected hepatic cystic echinococcosis. (cdc.gov)
Parasites2
- Parasites - echinococcosis. (medlineplus.gov)
- Diagnostic difficulties may occur in large cyst patients (with live parasites), as well as in patients with dead echinococcosis. (nls-diagnostic.org)
Elisa echinococcosis2
- Igg Elisa Laboratories manufactures the igg elisa echinococcosis serologic test reagents distributed by Genprice. (ayurvedandindia.com)
- The Igg Elisa Echinococcosis Serologic Test reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (ayurvedandindia.com)
Polycystic1
- Less common forms include polycystic echinococcosis and unicystic echinococcosis. (wikipedia.org)
Diagnosis2
- Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. (medscape.com)
- Relying on clinical and imaging results, the diagnosis of hydatid disease (infection by E. granulosus ) was suspected and staged as CE2, which refers to an active infection with many cyst-in-cyst lesions according to the World Health Organization (WHO) classification [ 4 ]. (biomedcentral.com)
Albendazole10
- The treatment of alveolar echinococcosis is multidisciplinary and may (1) combine surgery (radical resection of alveolar echinococcosis lesions, possible in 30% of cases) with albendazole anti-infective treatment for 2 years or (2) consist entirely of very long-term continuous albendazole treatment. (medscape.com)
- The current clinical therapeutic medicine against echinococcosis is albendazole, although it caused serious side effects in patients. (hindawi.com)
- In order to explore the effect and mechanism of SA treatment against echinococcosis, we established animal echinococcosis model and treated rats with albendazole alone, alkaloids alone, and combined therapy. (hindawi.com)
- Albendazole is the most common clinical drug to treat echinococcosis [ 4 ]. (hindawi.com)
- Clinically, its seeds decoction is combined with albendazole to treat echinococcosis [ 9 ]. (hindawi.com)
- In the present study, we not only investigated the therapeutic effect of the combinational treatment of Sophora moorcroftiana alkaloids and albendazole against echinococcosis in an experimental rats model, but also explored the underlying molecular mechanism of this strategy by proteomics. (hindawi.com)
- Albendazole and mebendazole are the only anthelmintics effective against cystic echinococcosis. (medscape.com)
- Treatment of echinococcosis for patients weighing more than 60 kg is albendazole administered PO with meals in a dose of 400 mg twice daily for 28 days. (medscape.com)
- Programme for ultrasound diagnoses and treatment with albendazole of cystic echinococcosis in asymptomatic carriers: 10 years of follow-up of cases. (medscape.com)
- its metabolite, albendazole-sulphoxide (ABZSO) Thirty mice were inoculated with protoscolices was shown to be an active anthelmintic agent of E. granulosus and divided into 5 groups. (medicpdf.com)
Zoonosis4
- ABSTRACT Cystic echinococcosis (CE) is a widespread helminth zoonosis, especially in rural areas. (who.int)
- Hydatid disease caused by E. granulosus is a zoonosis of major public health concern throughout Latin America, particularly in the Andean and South Cone regions. (med-chem.com)
- La equinococosis quística representa una grave zoonosis parasitaria en nuestro país y otros países en desarrollo dedicados a la ganadería. (edu.pe)
- Cystic echinococcosis is a serious parasitic zoonosis in our country and other developing countries dedicated to livestock. (edu.pe)
Parasitic disease1
- Alveolar echinococcosis is a rare pseudotumor zoonotic parasitic disease of the liver that is distinct from cystic echinococcosis. (medscape.com)
Liver5
- In all, we consider that the combinational treatment displayed better therapeutic effects against liver echinococcosis as well as alleviated liver injury, which could be considered as an effective strategy to treat echinococcosis clinically. (hindawi.com)
- In humans, ingested eggs can be mainly distributed to liver and lung, leading to cystic echinococcosis (CE) and alveolar echinococcosis (AE). (hindawi.com)
- Since their epidemiologic risk factors may be absent and clinical presentations varied, a high index of suspicion for echinococcosis is warranted in this population based solely on the presence of a cystic mass in liver, lung, or another organ site. (ajtmh.org)
- There was no clear relationship between the cystic tumor and the liver, which led to the assumption of primary extrahepatic cystic echinococcosis. (biomedcentral.com)
- Grubor NM, Jovanova-Nesic KD, Shoenfeld Y. Liver cystic echinococcosis and human host immune and autoimmune follow-up: A review. (wjgnet.com)
20184
- Surgically confirmed cases of cystic echinococcosis from Baluchistan Province, Pakistan for the years 2011-2018. (medindia.net)
- From 1992 to 2018, a total of nine human cases of alveolar echinococcosis were recorded in area I, five cases were recorded in study area III, and no cases were recorded in area II. (biomedcentral.com)
- A cross sectional study was conducted from January 2018 to April 2018 to determine the prevalence and associated risk factors of cystic echinococcosis in pig slaughtered at Addis Ababa abattoir enterprise, central part of Ethiopia. (ojafr.ir)
- 2018) Valoración de un nuevo ensayo quimioluminiscente en comparación con ELISA en la detección de IgG contra el virus de la hepatitis E. Revista de la Sociedad Andaluza de Microbiología y Parasitología Clínica. (vircell.com)
Hepatic8
- Hardware diagnostic results of 359 patients with complicated hepatic echinococcosis were analyzed. (nls-diagnostic.org)
- The results of commonly used hardware examination methods have shown that mixed analysis of these methods greatly increases specificity and sensitivity in preoperative diagnostics of complicated hepatic echinococcosis. (nls-diagnostic.org)
- According to various authors, information value of NLS method in case of hepatic echinococcosis depends on parasite development stage (live or dead), and is at least 90-97% on average. (nls-diagnostic.org)
- Radiographic diagnostic method is subsidiary and it may generally show indirect signs of complicated hepatic echinococcosis. (nls-diagnostic.org)
- Use of NLS (which in comparison to CT provides panoramic images and higher sensitivity superior in certain locations, accurate differential and regional diagnostics) was the next step in diagnostics improvement of complicated hepatic echinococcosis. (nls-diagnostic.org)
- The purpose of given research is to determinate the peculiarities of hepatic echinococcosis hardware diagnostics and its complications. (nls-diagnostic.org)
- Given research is based on clinical observations analysis of 359 patients suffering from complicated hepatic echinococcosis at Surgical pathologies department of Tadzhik State Medical University n.a. (nls-diagnostic.org)
- Complications in the form of hepatic echinococcosis suppuration and calcifications were registered in 279 (77.7%) patients. (nls-diagnostic.org)
Species1
- Information of E. granulosus species and genotypes has essential implications for epidemiology, management, and prevention of illnesses in addition to future vaccine and drug designs. (microarrayworld.com)
20201
- In 2020, an international effort of scientists, from 16 countries, led to a detailed consensus on terms to be used or rejected for the genetics, epidemiology, biology, immunology, and clinical aspects of echinococcosis. (wikipedia.org)
Humans1
- According to the results of our study, the sheep strain (G1) is the predominant genotype of E. granulosus in humans in our country. (bezmialem.edu.tr)
Genotype1
- The excessive incidence of the G1 genotype (recognized to be the predominant E. granulosus genotype infecting people globally) in sheep has appreciable implications for hydatid illness management packages on this space. (floatingharborsyndrome.co.uk)
Lesions1
- anti-scolecidal agents should never be injected into alveolar echinococcosis lesions. (medscape.com)
Epidemiological1
- To evaluate the serological, radiological and epidemiological analysis of suspected cystic echinococcosis patients, and to assess the positivity rate in the region. (org.pk)
Percutaneous1
- Justified concern or exaggerated fear: the risk of anaphylaxis in percutaneous treatment of cystic echinococcosis-a systematic literature review. (medscape.com)
Protoscolices1
- 2003). Both ABZ and ABZSO have been prophylactic groups, just after challenge with shown to be active against protoscolices of E. protoscolices, received 150 mg/kg BW /day granulosus in in vitro culture systems. (medicpdf.com)
Infection caused1
- E granulosus is an infection caused by tapeworms found in dogs and livestock such as sheep, pigs, goats, and cattle. (medlineplus.gov)
Indirect1
- The retrospective study was conducted at Bursa Uludag University Hospital, Bursa, Turkey, and comprised data from January 2009 to December 2017 related to patients of either gender with suspected cystic echinococcosis who underwent indirect haemagglutination testing. (org.pk)
Intermediate hosts1
- Parasitic modulation of the immune response allows E. granulosus to persist in intermediate hosts. (ac.be)
Adult2
- The adult worms of E. granulosus are very small (3 to 6 mm long) and consist of a scolex, neck, and only a single proglottid at each stage of development (immature, mature, and gravid). (med-chem.com)
- Therefore imnunoprotección was evaluated against E.granulosus using surface antigens as membrane proteins and metabolic products of excretion-secretion protoscoleces and adult worms. (edu.pe)
Gene1
- The partial sequences of mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was used for identification and molecular analysis of E. granulosus strains. (bezmialem.edu.tr)
Therapeutic2
- The incidence of alveolar echinococcosis is increasing because of the urbanization of its animal hosts and the growing use of therapeutic immune suppression, which increases susceptibility. (medscape.com)
- Thus, it is urgent to develop new therapeutic strategies against echinococcosis. (hindawi.com)
Clinical practice1
- As can be seen from the above, the introduction of NLS with SEA into clinical practice significantly improves diagnostics of complicated echinococcosis (especially in its early forms) which allows often performance of radical and, at the same time, economical intervention. (nls-diagnostic.org)
Sheep1
Molecular1
- There are a lot of molecular strategies developed to outline genotypes of E. granulosus, amongst them excessive decision melting (HRM) evaluation, as a brand new method, is a single step and closed tube methodology. (floatingharborsyndrome.co.uk)
Treatment2
- For cystic echinococcosis, the 28-day course may be repeated after 14 days without treatment to a total of 3 treatment cycles. (medscape.com)
- For alveolar echinococcosis , [NT005 trade name] is taken for a course of 28 days followed by 14 tablet-free days, and treatment cycles may need to be continued for months or years. (who.int)
Primary1
- Primary echinococcosis was registered in 293 (81.6%), relapsing echinococcosis in 37 (10.3%) and residual echinococcosis in 29 (8.1%) of the total number of observed patients. (nls-diagnostic.org)