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  • immune system
  • Immunostimulants, also known as immunostimulators, are substances (drugs and nutrients) that stimulate the immune system by inducing activation or increasing activity of any of its components. (wikipedia.org)
  • Non-specific immunostimulants act irrespective of antigenic specificity to augment immune response of other antigen or stimulate components of the immune system without antigenic specificity, such as adjuvants and non-specific immunostimulators. (wikipedia.org)
  • Other hormones appear to regulate the immune system as well, most notably prolactin, growth hormone and vitamin D. Some publications point towards the effect of deoxycholic acid (DCA) as an immunostimulant of the non-specific immune system, activating its main actors, the macrophages. (wikipedia.org)
  • activation
  • Thus, it is part of the immune/inflammatory cascade, by which activation of a small number of macrophages can rapidly lead to an increase in their numbers, a process crucial for fighting infection. (wikipedia.org)
  • physiological
  • A growing body of evidence indicates that these factors play a physiological role in the regulation of normal development of the pre-implanted embryo and that these factors therefore help to increase the implantation of the embryo and subsequently ensure optimal development of both foetus and placenta. (clinicaltrials.gov)
  • type
  • The crystal structures of IL1A and IL1B have been solved, showing them to share the same 12-stranded beta-sheet structure as both the heparin binding growth factors and the Kunitz-type soybean trypsin inhibitors. (wikipedia.org)
  • patients
  • Having successfully pioneered inhaled GM-CSF for over a decade in patients with pulmonary alveolar proteinosis (PAP), we were prompted to try the same approach to treat NTM infection after learning of the increasing scientific evidence of GM-CSF's important role in activating macrophages to kill mycobacteria. (benzinga.com)
  • effect
  • Although detailed precipitating events are still unknown, it is thought that the disease process is multifactorial.1 The additive effect of genetic and environmental factors, loss of tolerance to intestinal bacterial flora, and immune dysfunction predispose to this sustained immune response (1). (thefreelibrary.com)
  • Kinase
  • 10.Xin Xi, Shuang Liu, Hongtao Shi, Min Yang, Yongfen Qi, Jian Wang, Jie Du: Serum-Glucocorticoid Regulated Kinase 1 Regulates Macrophage Recruitment and Activation Contributing to Monocrotaline-Induced Pulmonary Arterial Hypertension. (54doctor.net)
  • Stem
  • It is thought that stability of the G-CSF mRNA is regulated by an RNA element called the G-CSF factor stem-loop destabilising element. (wikipedia.org)
  • gene
  • STWS is caused by a mutation in the leukemia inhibitory factor receptor ( LIFR ) gene, which is inherited in an autosomally recessive pattern. (biomedcentral.com)
  • properties
  • A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. (githubusercontent.com)