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  • BSIs
  • The guidance explains, for the purposes of the NHS ambition to reduce healthcare-associated Gram-negative BSIs, how these infections will be defined according to where they are detected (community or hospital settings), and key healthcare-associated risk factors. (improvement.nhs.uk)
  • This report summarizes the investigations of three clusters of gram-negative bacterial BSIs at hemodialysis centers in Canada, the United States, and Israel. (hdcn.com)
  • From December 5, 1996, through January 25, 1997, a total of 10 adult patients at an ambulatory hemodialysis center in Maryland had gram-negative bacterial BSIs. (hdcn.com)
  • From February 9 through September 19, 1997, eight adult patients at an ambulatory hemodialysis center in Jerusalem, Israel, had gram-negative bacterial BSIs. (hdcn.com)
  • Resistance
  • This handbook collates national resources on antimicrobial resistance, antimicrobial stewardship and infection prevention and control. (improvement.nhs.uk)
  • The Combatting Bacterial Resistance in Europe - Molecules against Gram Negative Infections (COMBACTE-MAGNET) consortium will provide groundbreaking multinational phase 2 and phase 3 studies in adult intensive care unit (ICU) patients and a phase 1 paediatric safety and PK study with the bispecific immunoglobulin (IgG)1 mAb (MEDI3902) targeting the pathogenic components PsI and PcrV as a new approach for preventing P. aeruginosa infections, especially pulmonary infections, in ICU patients. (europa.eu)
  • Outbreaks
  • Outbreaks of MDR infections adversely impact of patients quality of life, increase length of hospital stay and place considerable financial burdens on healthcare systems and services. (bsac.org.uk)
  • outer membrane
  • It is important to recognize that this class is defined morphologically (by the presence of a bacterial outer membrane), and not histologically (by a pink appearance when stained), though the two usually coincide. (wikipedia.org)
  • responses
  • The LPS-exposed mice develop strikingly high titers of polyclonal antibodies, prolonged hepatomegaly, and innate immune "tolerance" that gives them slow and inadequate responses to bacterial challenge. (wikipedia.org)
  • While its toxic effects can be damaging, the sensing of lipid A by the human immune system may also be critical for the onset of immune responses to gram-negative infection, and for the subsequent successful fight against the infection. (wikipedia.org)