• Mouse colon impacted by acute graft-versus-host disease. (wikipedia.org)
  • In the classical sense, acute graft-versus-host disease is characterized by selective damage to the liver , skin (rash), mucosa , and the gastrointestinal tract . (wikipedia.org)
  • Criteria used by hematologists/oncologists to diagnose acute graft-versus-host disease (GVHD), and common therapies used for GVHD prevention in patients who receive hematopoietic stem cell transplantation. (targetedonc.com)
  • Acute graft-versus-host disease is defined both clinically and pathologically. (targetedonc.com)
  • We also try to define acute graft-versus-host disease pathologically. (targetedonc.com)
  • So we define acute graft-versus-host disease clinically and confirm it pathologically. (targetedonc.com)
  • The frequency of acute graft-versus-host disease is highly dependent upon a number of factors. (targetedonc.com)
  • Risk factors for development of acute graft-versus-host disease depend upon the type of graft you're using-whether it's from an HLA [human leukocyte antigen]-matched sibling versus an HLA-matched unrelated donor, or if you're using a partially matched donor. (targetedonc.com)
  • The incidence of acute graft-versus-host disease is much higher when associated with a female donor. (targetedonc.com)
  • Therefore, the immune cells that are passively transferred in the stem cell graft are more primed against these minor histocompatibility antigens that are known to be associated with the development of acute graft-versus-host disease. (targetedonc.com)
  • Those are some of the most important risk factors for developing acute graft-versus-host disease. (targetedonc.com)
  • There's a wide variety of regimens that are used to prevent acute graft-versus-host disease. (targetedonc.com)
  • The goal of the trial was to evaluate drug-eluting stents (DES) compared with bare-metal stents (BMS) among patients with saphenous vein graft lesions undergoing percutaneous coronary intervention (PCI). (acc.org)
  • Objectives There are limited data on long-term outcomes (ie, beyond 4 years) for patients with unprotected left main bifurcation disease who underwent percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) in the drug-eluting stent (DES) era. (bmj.com)
  • To answer questions about the safety and durability of endoscopic vein-graft harvesting during CABG surgery, Williams and co-workers performed an observational study in 235,394 Medicare patients undergoing isolated first-time CABG surgery between 2003 and 2008 at 934 surgical centers participating in the STS national database.6 The STS records were linked to Medicare files to allow longitudinal assessment (median 3-year follow-up) through December 31, 2008. (hcplive.com)
  • Association between endoscopic vs. open vein graft harvesting and mortality, wound complications and cardiovascular effects in patients undergoing CABG surgery. (hcplive.com)
  • Chiefly, grafting is a viable way to gain more productivity with vegetables in the Solanaceae (or nightshade ) family, which includes tomatoes, peppers, eggplants, potatoes and ground cherries. (hobbyfarms.com)
  • Nightshade plants, like tomatoes, are best grafted just after their first set of true leaves is established. (hobbyfarms.com)
  • Newer research indicates that other graft-versus-host disease target organs include the immune system (the hematopoietic system , e.g., the bone marrow and the thymus ) itself, and the lungs in the form of immune-mediated pneumonitis . (wikipedia.org)
  • This essentially means avoiding positions or activities which overly stress the graft, such as uncontrolled knee hyperextension (forced over straightening), valgus stresses (stresses on the inside of the knee, taking the knee into 'knock knee' position) on a flexed knee and unrestrained anterior Tibial translation (forward movement of the shin bone), most commonly from the pull of the quadriceps during open kinetic chain knee extension activities. (physioroom.com)
  • Bone grafts can more closely mimic the chemical structure and composition of natural bone, thanks to a new material. (technologyreview.com)
  • The incidence of endoscopic harvesting increased over time such that in 2008, 70% of the vein-graft harvests were performed endoscopically. (hcplive.com)
  • The primary outcome, incidence of target vessel failure at 12 months (cardiac death, target vessel myocardial infarction [MI], or target vessel revascularization), occurred in 17% of the DES group versus 19% of the BMS group (p = 0.67). (acc.org)
  • This incidence rate demonstrates patients who are deemed to have clinically significant graft-versus-host disease. (targetedonc.com)
  • If you're doing an in vivo or ex vivo T-cell depletion, the incidence of graft-versus-host disease is going to be lower than when you do a T-cell-replete, for which you leave the T cells in the graft, or you don't try to significantly remove them afterward using monoclonal antibodies targeting T cells. (targetedonc.com)
  • Open kinetic chain hamstring curls would obviously also have potentially deleterious effects on the donor site of Hamstring graft patients. (physioroom.com)
  • Approach grafting-where the scion and stock are grown closely together, the stems are wounded and pressed together, and then the excess plant tissues are gradually severed after the graft is successful-works best for unions between tomatoes and potatoes. (hobbyfarms.com)
  • Graft-versus-host disease ( GvHD ) is a syndrome , characterized by inflammation in different organs. (wikipedia.org)
  • GvHD can also occur after a blood transfusion , known as Transfusion-associated graft-versus-host disease or TA-GvHD if the blood products used have not been gamma irradiated or treated with an approved leukocyte reduction system. (wikipedia.org)
  • [6] Chronic graft-versus-host disease also attacks the above organs, but over its long-term course can also cause damage to the connective tissue and exocrine glands . (wikipedia.org)
  • We primarily define graft-versus-host disease by involvement of 3 organs. (targetedonc.com)
  • Not to be confused with Host-versus-graft disease . (wikipedia.org)
  • Micrographs of grades of skin graft-versus-host disease: Ranging from grade I GvHR (with minimal vacuolization in the epidermis) to grade II GvHR (with vacuolization and dyskeratotic bodies) to grade III GvHR (with sub epidermal cleft formation) and finally to grade IV GvHR (with separation of the dermis from the epidermis). (wikipedia.org)
  • In the clinical setting, graft-versus-host disease is divided into acute and chronic forms, and scored or graded on the basis of the tissue affected and the severity of the reaction. (wikipedia.org)
  • It's important to realize that with graft-versus-host disease of the intestinal tract, 70% to 90% of the time a flexible sigmoidoscopy is sufficient for a patient with diarrhea. (targetedonc.com)
  • But it depends on what you're using for graft-versus-host disease prophylaxis. (targetedonc.com)
  • Another more frequently used method to prevent graft-versus-host disease is post-transplantation cyclophosphamide. (targetedonc.com)
  • The other major way to prevent graft-versus-host disease is through T-cell depletion, and that can be ex vivo, where the graft, before it's infused, goes through a process, usually through a selection column to remove T cells from the graft. (targetedonc.com)
  • In it, she describes a mode of using herbaceous grafts to make heirloom tomatoes -which are prized for their flavors and textures but often plagued with pest and disease problems-more vigorous by grafting them to compatible hardier hybrid rootstocks. (hobbyfarms.com)
  • After the grafts have healed, they can be transplanted out into the garden, and make either a conversation piece or a vigorous, tasty and disease-resistant supercrop. (hobbyfarms.com)
  • Because of this, greater care must be taken with hamstring graft patients to avoid pulling out of the graft from its non-osseous fixation point. (physioroom.com)
  • Patients with saphenous vein graft lesions undergoing PCI were randomized to DES (n = 292) versus BMS (n = 305). (acc.org)
  • Among patients with a saphenous vein graft lesion undergoing PCI, DES were not superior to BMS at preventing target vessel failure. (acc.org)
  • Relatively small trials had been inconclusive in evaluating the comparative effectiveness of DES versus BMS. (acc.org)
  • DIVA is one of the largest trials on the topic and revealed that the use of BMS for saphenous vein graft lesions (for potential cost savings) could be considered. (acc.org)
  • One of Lee's recently published articles was a systematic review of the use of the Hamstring tendon and the Patella tendon for use as a graft during Anterior Cruciate Ligament (ACL) surgery. (physioroom.com)
  • Because it has two bony fixation points, the Patella tendon graft is relatively more stable during the initial 6-8 weeks post surgery compared to the hamstring graft, which only has a single bony point of fixation. (physioroom.com)
  • In the short term (12-18 months following surgery), either graft site is likely not to be functioning normally. (physioroom.com)
  • Endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery. (hcplive.com)
  • In the early stages of rehabilitation, the programme for the two graft types will differ because of the differences in the nature of fixation that the operations are able to achieve. (physioroom.com)
  • There were no significant differences between long-term mortality rates (13.2% vs 13.4%) and the composite end point of death, MI, and the need for repeat revascularization between the open and endovascular techniques. (hcplive.com)
  • The most reliable method is tube grafting, which is the use of a narrow silicone tube or clip to bring the tissues of stock and scion together. (hobbyfarms.com)
  • The key to rehabilitating either graft type is to establish normal motion at the knee and patellofemoral joint, reduce any swelling and muscle inhibition around the knee and regain normal motion control of the lower limb. (physioroom.com)
  • The most frequent source of difference between early stage rehabilitation programmes for the two graft types is due to inter-surgeon variation, with some surgeons opting for 1-2 weeks immobilisation in an extension splint for hamstring grafts and unrestrained motion for Patella tendon. (physioroom.com)
  • Players with these types of injury and surgical repair need to be rehabilitated over long periods not merely until they have returned to play, in order to maximise the potential functional return of the graft sites. (physioroom.com)
  • vs. endoscopic saphenectomy: a prospective randomized trial. (hcplive.com)
  • It's especially important to use sharp and sterile grafting implements in grafting herbaceous plants, as the more delicate green plant tissues can be easily crushed by a dull blade and won't be able to form a vascular connection. (hobbyfarms.com)
  • New novelty grafted nightshades have made it to market in recent years, like the " Ketchup and Fries " or "Pomato" plant-a cherry tomato grafted onto a potato rootstock-and the "Egg and Chips" plant-an eggplant grafted to a potato rootstock. (hobbyfarms.com)
  • Although it took years to find the right cultivars to make these interspecific unions productive, they can be imitated at home by using the same tried-and-true combinations of cultivars as those used in store-bought pre-grafted plants. (hobbyfarms.com)
  • A few years ago, garden and environmental writer Anne Raver published a great article in The New York Times simply called " In Defense of Grafting . (hobbyfarms.com)
  • The invention is in the field of methods for treating and preventing GI Syndrome and Graft Versus Host Disease. (justia.com)
  • Doctors consider autografts the gold standard , but these grafts also have a higher risk of complications at the surgical site. (medicalnewstoday.com)
  • While removal of T cells from the donor marrow graft ameliorates GvHD, this strategy increases graft failure rates and markedly diminishes the therapeutically-beneficial graft-versus-tumor effect. (justia.com)
  • Therefore, about 28 documents of forgery, corruption, misuse of authority and other types of grafts by Hotak, the mayor of Zaranj, will be sent to you for investigation. (pajhwok.com)
  • This week we offer you two more very interesting short speeches from the first Enoforum Web Conference, where the results of research on the assessment of grafted vines quality through the use of X-Ray Tomography and the use of microorganism against the wood pathogens were presented. (infowine.com)