PseudohypoaldosteronismSalivary Duct CalculiLamin Type AClubfootAging, PrematureFarnesyltranstransferaseCell Nucleus ShapeNuclear LaminaWerner SyndromePrenylationProtein PrecursorsProtein PrenylationAmino Acid SequenceBone Demineralization, PathologicFibroblastsNuclear EnvelopeNuclear ProteinsSkin AbnormalitiesLaminsProtein Modification, TranslationalLamin Type BOrganelle ShapeContractureLipodystrophyMaxillofacial AbnormalitiesMetalloendopeptidasesCell AgingSomatotrophsCockayne SyndromeCell NucleusAgingBone Diseases, DevelopmentalPhenotypeMutationSyndromeAlkyl and Aryl TransferasesProgeriaHeterochromatinLongevityCells, CulturedMembrane ProteinsSkinDisease Models, AnimalEnzyme InhibitorsDNA RepairHeterozygoteMitosisDNA DamageBone and BonesMice, TransgenicCell LineMice, KnockoutProtein Binding