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  • mRNA
  • The same phenotype is produced in embryos that have been depleted of maternal beta-catenin protein by an antisense oligodeoxynucleotide complementary to beta-catenin mRNA. (nih.gov)
  • repressor
  • Repressor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release. (harvard.edu)
  • This graph shows the total number of publications written about "Repressor Proteins" by people in Harvard Catalyst Profiles by year, and whether "Repressor Proteins" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Repressor Proteins" by people in Profiles. (harvard.edu)
  • One of the principal differences between HTH motifs in these different proteins arises from the stereo-chemical requirement for glycine in the turn which is needed to avoid steric interference of the beta-carbon with the main chain: for cro and repressor proteins the glycine appears to be mandatory, while for many of the homeotic and other DNA-binding proteins the requirement is relaxed. (embl.de)
  • histone
  • One member of the forkhead protein family is HILS1, a spermatid -specific histone -like protein that may function in gene regulation and chromatin remodeling ( Yan , 2003). (sunyorange.edu)
  • dorsal
  • They show an inhibition in the expression of dorsal mesodermal markers MyoD and goosecoid, but not of ventral and general mesodermal markers. (nih.gov)
  • sequence
  • A large family of structurally-related transcription factors that were originally discovered based upon their close sequence homology to an HMG-box domain found in SEX-DETERMINING REGION Y PROTEIN. (harvard.edu)
  • The HMG family are a set of proteins made of 3 a helices and a 79 amino acid conserved sequence called the HMG Box (most proteins have only one such sequence). (sunyorange.edu)
  • A superfamily of proteins that share a highly conserved MADS domain sequence motif. (ucdenver.edu)
  • Abnormalities
  • craniofacial imaging reveals abnormalities in both skull and jaws that may arise through misregulation of goosecoid, a downstream target of Gtf2ird1. (ox.ac.uk)
  • differentiation
  • Among its related pathways are Regulation of retinoblastoma protein and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers . (genecards.org)
  • We focus on the principal canonical transduction proteins (R-Smads) of the TGFβ pathway, which instruct both axial patterning and tissue differentiation in the developing embryo. (biomedcentral.com)
  • amino
  • This helix-turn-helix (HTH) motif is only about 20 amino acids long and other parts of HTH proteins control the binding of the HTH region only at specific sites on the DNA molecule. (sunyorange.edu)
  • complexes
  • Recent biophysical analysis of the PRH protein has shown that it forms homo-oligomeric complexes in vivo and in vitro and that the proline-rich region of PRH forms a novel dimerization interface. (biochemj.org)