Dose-Response Relationship, DrugMolecular Sequence DataCells, CulturedCell LineSignal TransductionProtein BindingAmino Acid SequenceTime FactorsRNA, MessengerBase SequenceKineticsPhosphorylationGene Expression RegulationCell Line, TumorBinding SitesMutationTranscription FactorsCalciumApoptosisTranscription, GeneticRats, Sprague-DawleyModels, BiologicalDNA-Binding ProteinsTransfectionPromoter Regions, GeneticBlotting, WesternEnzyme InhibitorsEnzyme ActivationProtein Structure, TertiaryMice, Inbred C57BLRecombinant Fusion ProteinsCell ProliferationReverse Transcriptase Polymerase Chain ReactionTumor Cells, CulturedGene ExpressionMembrane ProteinsHeLa CellsCell SurvivalCell DivisionDNAReproducibility of ResultsCarrier ProteinsNuclear ProteinsCattleNeuronsCell MembraneRabbitsCell DifferentiationRats, WistarProteinsPeptidesMice, KnockoutCloning, MolecularProtein-Serine-Threonine KinasesDNA PrimersProtein TransportUp-RegulationSequence Homology, Amino AcidCell NucleusDown-RegulationFibroblastsRNA, Small InterferingCricetinaeAdenosine TriphosphateModels, MolecularCell CycleImmunohistochemistryBrainPlasmidsTranscriptional ActivationEscherichia coliPlant ExtractsBinding, CompetitiveCell MovementMice, TransgenicBacterial ProteinsTreatment OutcomeFlow CytometryLiverMice, Inbred BALB CPhenotypePeptide FragmentsLigandsMicroscopy, FluorescenceTrans-ActivatorsRNA InterferenceHydrogen-Ion ConcentrationGene Expression Regulation, DevelopmentalProtein Kinase CCyclic AMPCell AdhesionGenes, ReporterHEK293 CellsCOS CellsSequence AlignmentEpithelial CellsNF-kappa BImmunoblottingBiological TransportStructure-Activity Relationship