Gm genes. Medical search. Frequent questions

The GM Approval Database, or GMAD, is one of ISAAA's unique features that compiles all the available information about biotech/GM crops that have been approved for planting and importation for food and feed, and commercialization. (isaaa.org)
If crops and animals developed by gene-editing techniques are officially considered non-GM, or exempted from the EU GMO regulations, then they will enter the food chain and the environment completely unregulated and unlabelled. (theecologist.org)
But the reality is that gene editing is simply GM 2.0, with many of the same concerns and problems as the GM crops that Europeans have already rejected. (theecologist.org)
With current commercial GM crops, one of the major concerns is that unexpected effects can result, and have resulted, from the genetic engineering process, and these can affect food and environmental safety. (theecologist.org)
Four genetically modified (GM) crops have been approved for cultivation in Australia: cotton, canola, Indian mustard and safflower. (ogtr.gov.au)
This factsheet is an introduction to the regulation of GM crops in Australia. (ogtr.gov.au)
It is supported by a suite of factsheets with more detailed information for anyone with an interest in or concerns about GM crops. (ogtr.gov.au)
The recent revelation of a toxic gene lurking in genetically modified (GM) crops underscores the failure of food approval regulators to protect the public - again. (wakeup-world.com)
New research by the European Food Safety Authority (EFSA) shows the missed gene is present in GM corn and soy crops grown around the globe for both human and animal consumption. (wakeup-world.com)
Humans not only ingest the gene directly from eating GM corn and soy products but also indirectly from eating the meat, milk and eggs from the animals fed the crops. (wakeup-world.com)
As the research was conducted by independent experts rather than scientists critical of GM crops, the findings are particularly powerful. (wakeup-world.com)
In the aftermath of the new revelation, critics are declaring the GM approval process to be fatally flawed and asserting that the crops involved should be recalled. (wakeup-world.com)
Research clearly indicates the gene might be unsafe for humans and may also interfere with the normal functioning of crops, it added. (wakeup-world.com)
He explains that the failure of the approval system to discover the viral gene is what happens in the absence of independent scrutiny of GM crops. (wakeup-world.com)
Gene flow in agricultural crops is important for risk assessment of genetically modified (GM) crops, particularly in countries with a large informal agricultural sector of subsistence cultivation. (nature.com)
Few countries have adopted genetically modified (GM) crops for commercial use on the African continent. (nature.com)
With a potential increase in the adoption of GM crops in Africa in the coming years, better understanding of the implications of introducing GM crops into small-scale farming systems is needed. (nature.com)
The study, published in the journal GM Crops & Food , revealed a consistent difference between the favorability of gene editing and GMOs, with gene editing enjoying substantially higher favorability ratings than GMOs. (sciencedaily.com)
Are there trade implications if the UK starts growing gene-edited crops and the EU doesn't? (nfuonline.com)
Could gene-edited crops be grown alongside conventional and organic crops? (nfuonline.com)
Head researcher Tim Reinbott makes clear that GM crops are now part of the problem, due to herbicide-resistant superweeds. (gmwatch.org)
The take-home lesson is that GM crops are an outdated technology. (gmwatch.org)
Councillors voted on 15 April to make the Highlands the first area in Scotland to be declared free of GM crops. (gmwatch.org)
Crucial practical measures that can reduce vertical gene flow include (1) isolating seed production of Brassica napus , (2) the use of certified seed, (3) isolating fields of GM oilseed rape, (4) harvesting at the correct crop development stage with properly adjusted combine settings, (5) ensuring maximum germination of shed seeds after harvest, (6) controlling volunteers in subsequent crops, and (7) keeping on-farm records. (cambridge.org)
The training was part of a series of programs designed for editors and journalists to build on their understanding of biotechnology, Ghana's biosafety regulatory system, and the implications for food security and economic growth as the country gears up for GM crops commercialization . (isaaa.org)

But, as yet largely unnoticed is that the European Commission is considering whether the gene-editing of plants and animals, for example in agriculture, be exempted from regulation or even falls outside the scope of EU law governing genetically modified organisms (GMOs). (theecologist.org)
If you are importing genetically modified grain or you are importing genetically modified organisms (GMOs) on behalf of researchers, then you have specific obligations under the Gene Technology Act 2000. (ogtr.gov.au)
When gene technology is used to create a genetically modified (GM) plant, animal or other living thing (organism), the genetically modified organism (GMO), for example GM canola, is regulated by the Gene Technology Regulator to protect people and the environment. (ogtr.gov.au)
Gene editing and genetically modified organisms (GMOs) have been topics of significant debate in recent years. (sciencedaily.com)
Grass would possibly switch genes from their neighbours in the similar manner genetically changed plants are made, a brand new learn about has published. (clichetv.news)
The government's scientific advisory committees have repeatedly tried to reassure the public that there is nothing to fear from genetically modified (GM) DNA, but critics disagree. (i-sis.org.uk)
DNA is DNA is DNA," said a proponent in a public debate in trying to convince the audience that there is no difference between genetically modified (GM) DNA and natural DNA, "DNA is taken up by cells because it is very nutritious! (i-sis.org.uk)
Genetic modification is essentially horizontal gene transfer and recombination, speeded up enormously, and totally unlimited in the source of genetic material recombined to make the GMDNA that's inserted into the genomes plants, animals and livestock to create genetically modified organisms (GMOs). (i-sis.org.uk)
A coalition of consumer, health, food safety and fishing groups have launched the "Campaign for Genetically Engineered (GE)-Free Seafood" by announcing that several major grocery retailers representing more than 2,000 stores across the US have committed not to sell GM seafood if it is allowed onto the market. (gmwatch.org)
What is a Genetically Modified (GM) Food? (slideplayer.com)
Gene drives are a technology through which a few genetically engineered individuals are designed to intentionally push new genes through an entire population of a species in the wild. (cban.ca)

A genome-wide study in a northern European population replicated the association of SLE with susceptibility genes related to B-cell receptor pathway signaling, as well as confirmed the association of SLE with genes at the interferon regulatory factor 5 (IRF5)-TNPO3 locus. (medscape.com)
Development of asthma is multifactorial and depends on the interactions among multiple susceptibility genes and environmental factors. (msdmanuals.com)

However gene-edited organisms clearly fall within the definition of GMOs in both European and international law. (theecologist.org)
In other words, whether the products of gene-editing should be labelled and regulated as GMOs, or allowed to enter the food chain untested and unlabelled. (theecologist.org)
Many of these techniques can be used to insert genes from an unrelated species into a plant or animal as traditional genetic engineering does and the resulting products, with their novel genes would be regarded as GMOs. (theecologist.org)
The question is whether plants and animals with 'edited' genes (without inserted novel genes) should be regulated as GMOs. (theecologist.org)
A new study has revealed a positive shift in public sentiment towards one aspect of agricultural biotechnology, showing that gene editing consistently receives higher favorability ratings than GMOs in both social and traditional English-language media. (sciencedaily.com)
A new study from the Alliance for Science, an initiative based at the Boyce Thompson Institute, has revealed a positive shift in public sentiment towards one aspect of agricultural biotechnology, showing that gene editing consistently receives higher favorability ratings than GMOs in both social and traditional English-language media. (sciencedaily.com)
This could be the result of the relative novelty of gene editing as an issue, which has not -- unlike GMOs -- been the subject of a decades-long campaign of negative publicity by opponents," Lynas explained. (sciencedaily.com)
The research team also noted that the scientific community may have learned from its early deployment of GMOs and made efforts to avoid repeating them as gene editing is used more extensively. (sciencedaily.com)
Unlike GMOs that have thus far been engineered for confined use in agricultural production, gene drive organisms are expressly designed for intentional release into the wild . (cban.ca)

Australian farmer Geoffrey Carracher, who is against GM farming, with some canola seed that has been cross contaminated with GM seed from a nearby farm. (theecologist.org)
This fact sheet provides information for the control of unwanted herbicide-tolerant GM canola for example along roadsides. (ogtr.gov.au)
Beckie , H , Warwick , S , Nair , H , Séguin-Swartz G ( 2003 ) Gene flow in commercial fields of herbicide-resistant canola ( Brassica napus ). (cambridge.org)

Whether you are a member of the public or a community organisation, the Office of the Gene Technology Regulator (the OGTR) invites your involvement. (ogtr.gov.au)

Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease in the U.K. In a statement on Thursday, Nov. 16, 2023, the Medicines and Healthcare Regulatory Agency said it approved Casgevy, the first medicine licensed using the gene editing tool CRISPR, which won its makers a Nobel prize in 2020. (myfox8.com)
Gene;875: 147501, 2023 Jul 30. (bvsalud.org)

But not all the applications of gene-editing involve the insertion of novel genes. (theecologist.org)
In contrast to some previously described early genes, most of the novel genes are not induced in cortex by apomorphine, indicating specificity of induction. (jneurosci.org)

Traditional' genetic engineering involves the random insertion of genes (or genetic sequences) into an organism's genome. (theecologist.org)
It may also be the case that gene editing -- which largely involves DNA alterations that could possibly happen in nature -- is less inherently 'scary' than transgenic techniques transferring DNA sequences between unrelated species," Lynas added. (sciencedaily.com)
Studies on the GM process have shown that the foreign gene inserts invariably damages the genome, scrambling and rearranging DNA sequences, resulting in inappropriate gene expression that can trigger cancer [3, 4]. (i-sis.org.uk)
Comparison of amino acid sequences of polypeptides encoded by mau genes from M. extorquens AM1, P. denitrificans, and Thiobacillus versutus shows that they have considerable similarity. (caltech.edu)
has been identified as the 2nd most consensus (ERIC) sequences which · 60 environmental samples were tak- frequent organism causing ventilator- are common to Gram-negative enteric en throughout the ICU, including associated pneumonia, the 4th most bacteria [11,12]. (who.int)

Research, led by way of the University of Sheffield, is the primary to turn the frequency at which grasses incorporate DNA from different species into their genomes thru a procedure referred to as lateral gene switch. (clichetv.news)
The Sheffield staff sequenced a couple of genomes of a species of tropical grass and decided at other time issues in its evolution what number of genes have been received - giving a charge of accumulation. (clichetv.news)
Horizontal gene transfer happens when foreign genetic material jumps into genomes, creating new combinations (recombination) of genes, or new genomes. (i-sis.org.uk)
The problem with the GM inserts is that they could transfer again into other genomes with all the attendant risks mentioned. (i-sis.org.uk)
As the sequencing and gene annotation projects of entire genomes of many species are headed towards completion (see, e.g. [13] ), massive mapping efforts in biology are now focused on how the genes interact. (lu.se)

Researchers are also devising a type of gene-drive mechanism for mammals, and have outlined a hypothetical gene drive system intended to drive a desired trait though a herd or population of a farm animal. (cban.ca)

The re-emergence of stem rust on wheat in Europe and Africa is reinforcing the ongoing need for durable resistance gene deployment. (nature.com)
Target Malaria has begun releasing GM "male-sterile" mosquitoes in Burkina Faso , West Africa, for training purposes and to test the infrastructure they would use to release gene-drive mosquitoes in the future. (cban.ca)
The report posits that the generation and translation of genomic findings into guidelines tailored to the specific needs and profiles of African populations could advance GM for public health in Africa. (cdc.gov)
In this blog post, we discuss the benefits of African populations' representation in human genomic research as well as opportunities and challenges for implementing GM in Africa. (cdc.gov)
This report presents the status of AMR in Africa by analysing the main types of resistance and the underlying genes where possible. (who.int)

Mutational genomics and targeted exome capture identify Sr26 and Sr61 as separate single genes that encode unrelated (34.8%) nucleotide binding site leucine rich repeat proteins. (nature.com)
The mauB, mauA, and mauC genes encode the periplasmic methylamine dehydrogenase (MADH) large and small subunit polypeptides and amicyanin, respectively. (caltech.edu)

That is why the EU has set up regulations for GM organisms, requiring them to undergo an environmental and health risk assessment before they are grown or reared commercially or enter the food chain. (theecologist.org)

Mapping of the oil palm tree genome has revealed a single gene responsible regulating its yield, offering the possibility to breed new variants for increased production, say scientists behind the project. (foodnavigator.com)
Since genetic dissection of genes within alien segments in wheat was not possible due to lack of recombination, the question arose as to whether the apparent durability of such resistances might be due to multiple genes rather than a single gene. (nature.com)
Several single gene disorders share clinical and radiologic characteristics with multiple sclerosis and have the potential to be overlooked in the differential diagnostic evaluation of both adult and paediatric patients with multiple sclerosis. (medscape.com)
Recognition of a single-gene disorder as causal for a patient's 'multiple sclerosis-like' phenotype is critically important for accurate direction of patient management, and evokes broader genetic counselling implications for affected families. (medscape.com)
Here we review single gene disorders that have the potential to mimic multiple sclerosis, provide an overview of clinical and investigational characteristics of each disorder, and present guidelines for when clinicians should suspect an underlying heritable disorder that requires diagnostic confirmation in a patient with a definite or probable diagnosis of multiple sclerosis. (medscape.com)

The EU is considering the exclusion of gene-edited plants and animals from GM regulations, write Janet Cotter & Ricarda Steinbrecher. (theecologist.org)
If you believe the proponents' claims, gene-editing is nothing more than the 'tweaking' of DNA in plants and animals - nothing to be concerned about. (theecologist.org)
The study reveals that 54 of the 86 GM plants in the US authorized for commercial growing and food contain the dangerous gene. (wakeup-world.com)
Maize gene flow occurs through cultivator determined seed selection and mixing as well as through pollen transfer between individual plants and fields. (nature.com)
Gene flow occurs between all sexually compatible plants of maize types, i.e. in land races, commercial hybrids and eventual wild relatives 4 . (nature.com)
Tables of all current commercially released GM plants in Australia and their OECD unique identifiers. (ogtr.gov.au)
These findings, printed within the magazine New Phytologist may just tell long run paintings to harness the method to strengthen crop productiveness and make extra resilient plants, and feature implications on how we view and use debatable GM plants. (clichetv.news)
Dr. Luke Dunning, Research Fellow from the University of Sheffield's School of Biosciences, and senior writer of the analysis, stated: "There are many how you can make GM plants, some which require considerable human intervention and a few that do not. (clichetv.news)
Currently, these 'natural' reproductive contamination methods are not as efficient in producing GM plants as those that are used routinely, but by further understanding how lateral gene transfer occurs in the wild we may be able to increase the success of this process. (clichetv.news)

GM technologies involve inserting new DNA into an organism's genome, giving the resulting plant or animal desired characteristics. (nfuonline.com)

Most of the COL7A1 gene mutations responsible for RDEB-sev gen result in production of abnormally short pro-α1(VII) chains that cannot form type VII collagen. (medlineplus.gov)
[ 6 ] However, the gene mutations responsible for the different forms of CMT1 are clearly myelin genes. (medscape.com)

The NFIB gene is a protein coding gene that also serves as a transcription factor. (wikipedia.org)

GMDNA often contains antibiotic resistance marker genes needed in the process of making GM organisms, but serves no useful function in the GM organism. (i-sis.org.uk)

Watch wheat geneticist Cristobal Uauy explaining crop breeding and gene editing to the 2019 Oxford Farming Conference. (nfuonline.com)
There are gene-editing applications in at least 46 different crop species, with rice, tobacco, tomato, maize, wheat and soybean among the most cited. (nfuonline.com)
Most recently, scientists at Rothamsted Research and the University of Bristol have used gene editing to develop a type of wheat that is less likely to produce carcinogenic acrylamide when baked . (nfuonline.com)
The first trial started in autumn 2021 , the first such trial of gene-edited wheat to be carried out anywhere in Europe. (nfuonline.com)
Here, we isolate from wheat, Sr26 and Sr61 , with both genes independently introduced as alien chromosome introgressions from tall wheat grass ( Thinopyrum ponticum ). (nature.com)
Using gene-specific markers, we validate the presence of both genes on a single recombinant alien segment developed in wheat. (nature.com)
derived Sr gene, Sr61 (previously designated SrB ), was identified in South African wheat accession W3757, which carries a 6Ae#3 (6D) chromosome substitution 16 . (nature.com)
Please keep the momentum going by saying no to GM wheat - see our very important CAMPAIGN OF THE WEEK. (gmwatch.org)

That's because each species comes onto the evolutionary stage in its own space and time, and only those species that overlap in space and time could ever exchange genes at all in nature. (i-sis.org.uk)
The release of gene drive organisms is designed to alter the genetic make-up of an entire wild population, or to eradicate a population or species. (cban.ca)

Importantly, these gene-to-gene interactions within the cell are reflected in the organism as a whole. (theecologist.org)

15 Possible Risks for GM Foods  Certain gene products may be allergens, thus causing harm to human health  There may be unintended harm to wildlife and beneficial insects Photo courtesy of T. W. Davies, Cal. (slideplayer.com)
However, the most advanced research so far is in insects, specifically in gene drive systems that would alter genes to prevent mosquitoes from reproducing effectively, thus reducing the size of particular mosquito populations. (cban.ca)
ETC Group analysis ( 2018) of two key patents on gene drives show that they each reference around 500-600 agricultural uses including brand names of 186 herbicides, 46 pesticides, 310 agricultural pest insects, nematodes, mites, moths and others. (cban.ca)

Among the dyskeratosis congenita genes, mutations in TERC , TERT and DKC1 have recently been reported to be associated with familial pulmonary fibrosis and idiopathic pulmonary fibrosis, and pulmonary fibrosis is recognised as one of the features of dyskeratosis congenita. (ersjournals.com)
However, the relationship between mutations in the other dyskeratosis congenita genes and pulmonary fibrosis has not yet been clarified. (ersjournals.com)
Pulmonary toxicity and gene expression changes in response to whole-body inhalation exposure to multi-walled carbon nanotube s in rats. (cdc.gov)

Some of the induced genes, such as CREM, CHOP, and MAP kinase phosphatase-1, may be components of a homeostatic response to excessive stimulation. (jneurosci.org)

By interrogating microarray data from neuronal cells treated with inhibitors of different specificity, we selected two genes encoding histone macroH2A ( H2AFY2 ) and Polycomb group ring finger 2 ( PCGF2 ) that were specifically down-regulated by the inhibitors targeting HDACs1 and 3 versus the more selective inhibitors for further investigation. (frontiersin.org)

Gene-editing techniques may perhaps be more precise at the level and point where the DNA is altered but how this altered DNA might affect interactions with other genes and processes within the cell is largely unknown. (theecologist.org)
The molecular interactions of genes and gene products underlie fundamental questions of biology. (lu.se)

CRISPR is becoming well known in scientific circles as it's a particularly efficient method of gene-editing. (theecologist.org)
To discover what they are, a research team led by Nicholas Restifo at the US National Cancer Institute began with human melanoma cells growing in a dish, and systematically disabled every gene in the melanoma cells using the CRISPR gene-editing technique. (cosmosmagazine.com)
In a statement Thursday, the Medicines and Healthcare Regulatory Agency said it approved Casgevy, the first medicine licensed using the gene editing tool CRISPR, which won its makers a Nobel prize in 2020. (myfox8.com)
The future of life-changing cures resides in CRISPR based (gene-editing) technology," said Dr. Helen O'Neill of University College London. (myfox8.com)

With GM, however, there's no limit whatsoever: even DNA from organisms buried and extinct for hundreds of thousands of years could be dug up, copied and recombined with DNA from organisms that exist today. (i-sis.org.uk)
Releasing gene drive organisms can therefore be understood as a form of ecosystem engineering . (cban.ca)
Once released, gene drive organisms cannot be recalled, and the changes they create in the genetic make-up of the population are most likely irreversible. (cban.ca)

The nucleotide sequence of the methylamine utilization (mau) gene region from Methylobacterium extorquens AM1 was determined. (caltech.edu)

Well done all those who asked California Governor "Arnie" and other officials to terminate Ventria's GM pharma rice (HIGHLIGHTS OF THE WEEK - GLOBAL). (gmwatch.org)
The CSIR is currently undertaking field trials for GM rice and cowpea.Plans are at an advanced stage for environmental release application of cowpea in the year 2018-19. (isaaa.org)

June 2021 - The European Parliament has called for b an on gene drive technology. (cban.ca)

these effects are thought to involve alterations in gene expression. (jneurosci.org)

After years of denial, some European countries began to carry out 'event-specific' molecular analyses of the GM inserts in commercially approved GM varieties as required by the new European directives for deliberate release, novel foods and traceability and labelling. (i-sis.org.uk)

Once tumors were established, the surgical site tumor was debulked and vaccination of syngeneic tumor transfectants encoding genes for IL-4, IL-2, GM-CSF, B7-1 or allogeneic MHC molecules commenced at a site away from both tumors, and tumor growth was measured. (edu.au)
Neither debulking surgery nor gene therapy alone delayed tumor growth. (edu.au)
However, there was a clear delay of tumor growth when debulking surgery was combined with vaccination of tumor transfectants expressing B7-1 or high levels of GM-CSF. (edu.au)
This study demonstrates that debulking surgery can augment the immunostimulatory effects of immunological gene therapy and can delay tumor growth. (edu.au)
The main emphasis is on supervised machine learning methods for classification and prediction of tumor gene expression profiles. (lu.se)

Thus, the potential for exporting maize to markets with premium prices (e.g. organic), requires control over rates of cross-hybridisation between GM and non-GM maize. (nature.com)

Conservation and variation of the parapoxvirus GM-CSF inhibitory factor (GIF) proteins. (cdc.gov)
Among these effects, growth-defective 60S mutants increased synthesis of proteins involved in proteasome-mediated degradation, whereas 40S mutants accumulated mature 60S subunits and increased translation of ribosome biogenesis genes. (broadinstitute.org)

LONDON (AP) - Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease in the U.K. (myfox8.com)

These "test" GM (not gene drive) mosquitoes will not offer any benefits for malaria control in Burkina Faso. (cban.ca)

Calyno, a healthier oil (high oleic, low linolenic resulting in reduced trans-fatty acids associated with cardiovascular disease) which is produced from a variety of gene-edited soybean and has been on the US market since 2019. (nfuonline.com)

In agriculture, applications are being discussed to alter genes so that agricultural pests such as a type of fruit fly (spotted wing drosophila) and pigweed ( Palmer amaranth ) do not reproduce effectively, in order to make them ultimately go extinct. (cban.ca)

The positive coverage of agricultural gene editing in both traditional and social media is encouraging," said Dr. Sheila Ochugboju, Executive Director of the Alliance for Science. (sciencedaily.com)
Addressing members of the Ghana Agricultural and Rural Development Journalists (GARDJA) at a training on the basics of biotechnology , Mr. Debrah emphasized that GM technology is one of the several available options to help improve agricultural production and exuded confidence that the technology will offer farmers the best opportunity to scale up food production. (isaaa.org)

Although some single genes have been implicated to play a causative role in SLE, current knowledge points toward a large number of genes being involved in a multifactorial-type inheritance pattern in most patients. (medscape.com)
The gene drive mechanism ensures that new genes will be inherited by all offspring (as opposed to an expected half of the offspring in normal inheritance) in subsequent generations. (cban.ca)
Better understanding of new mutations and the wide range of possible phenotypes led to the development of a new nomenclature proposal, based on the gene and inheritance pattern. (medscape.com)

The co-location of these genes on a small non-recombinogenic segment simplifies their deployment as a gene stack and potentially enhances their resistance durability. (nature.com)
tritici ( Pgt ) races over the past two decades 1 , 2 has motivated global efforts to identify effective stem rust (Sr) resistance genes. (nature.com)
Consequently, there is an ongoing need to expand resistance resources and to enhance gene stewardship through co-deployment of multiple resitance (R) genes, rather than single genes, to increase resistance durability. (nature.com)
However, as there is no current Pgt race known to be virulent to either resistance gene, it was not possible to unambiguously determine whether the recombinant introgression carried a single or both genes. (nature.com)
Antimicrobial resistance occurs through different mechanisms, which include spontaneous (natural) genetic mutations and horizontal transfer of resistant genes through deoxyribonucleic acid (DNA). (who.int)

Peter Melchett of the Soil Association says that for years GM companies have deliberately attempted to stop independent researchers from evaluating their products. (wakeup-world.com)
[ 10 ] The protein products of the HLA genes are critical components of cell-to-cell communication in the immune system. (medscape.com)
Vertical gene flow from transgenic oilseed rape to non-GM counterparts may also have an impact on farming and supply chain management, depending on labelling thresholds for the adventitious presence of GM material in non-GM products. (cambridge.org)
Measuring which genes and gene products are active can be done on two levels. (lu.se)

As an additional factor contributing to gene flow, we present data on seed saving and sharing among farmers that live in the same communities. (nature.com)

The Act hijacks the constitution and puts Monsanto and other GM companies above the federal courts. (gmwatch.org)

A set of the matching Fountain Pen & Card Case featuring the "GM Horizontal" and "GM Vertical" designs from designer Gene Meyer. (acmestudio.com)
Horizontal gene transfer and recombination go hand in hand. (i-sis.org.uk)
By enhancing both the rate and scope of horizontal gene transfer and recombination, GM has also increased the chance of generating new disease-causing viruses and bacteria [1, 2]. (i-sis.org.uk)
There are reasons to believe GM inserts are more likely to undergo horizontal transfer and recombination than natural DNA [1-4], chief among which is that the GM inserts (and the GM varieties resulting from them) are structurally unstable, and often contain recombination hotspots (such as the borders of the inserts). (i-sis.org.uk)

Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate. (broadinstitute.org)
Because gene expression defects resulting from ribosome deficiency have not yet been experimentally defined, we systematically probed mRNA, translation, and protein signatures that were either unlinked from or linked to cellular growth rate in RP-deficient yeast cells. (broadinstitute.org)
TTC expansion mutation is to reduce expression of frataxin at the level of transcription ( 3 ), through the formation of heterochromatin and subsequent gene silencing ( 4 - 8 ). (frontiersin.org)
Using the 6-hydroxydopamine lesion model of Parkinson's disease and differential display PCR, we have identified a set of more than 30 genes whose expression rapidly increases in response to stimulation of striatal dopamine D 1 receptors. (jneurosci.org)
The induced mRNAs include both novel and previously described genes, with diverse time courses of expression. (jneurosci.org)
these gene expression changes may be responsible for the alterations in striatal physiology. (jneurosci.org)
One example is dynorphin gene expression, which is progressively induced in dorsal striatum by cocaine. (jneurosci.org)
This is not surprising given the strong evidence for interaction between myelin and axon gene expression in development and after experimental nerve lesions. (medscape.com)
Materials and methods: Rats were exposed, by whole-body inhalation, to air or an aerosol containing MWCNT-7 particles at target cumulative doses (concentration x time) ranging from 22.5 to 180 (mg/m3)h over a three-day (6 hours/day) period and toxicity and global gene expression profiles were determined in the lungs. (cdc.gov)
A brief introduction to high throughput technologies for measuring and analyzing gene expression is given. (lu.se)
Using such probes, one can obtain a fingerprint of the gene expression activity in a macroscopic sample. (lu.se)
Microarrays are one such tool that allows for the study of expression of thousands of genes simultaneously. (lu.se)
In what follows we limit ourselves to the analysis of gene expression measurements obtained using microarrays with small spots of DNA fixed to glass slides. (lu.se)
Levels of gene expression are measured using a preparation of fluorescently labeled tissue RNA (copies of DNA), together with reference RNA labeled with a different fluorochrome, hybridized onto the slides. (lu.se)

The mauA, mauD, and mauE genes from Paracoccus denitrificans and the mauD and mauG genes from Methylophilus methylotrophus W3A1 were able to complement corresponding mutants of M. extorquens AM1, confirming their functional equivalence. (caltech.edu)
Polymorphism of the complement C8A and -B genes in two families with C8 beta deficiency and neisserial infections. (lu.se)

This has implications for the future design of human gene therapy trials for solid tumors such as MM. (edu.au)

Pete Riley, director of GM Freeze, says the gene's discovery completely refutes assurances that GM technology is safe and is a clear warning that it is not well understood. (wakeup-world.com)

iii) modeled rates of pollen-mediated gene flow showed extensive mixing of germplasm between fields and farms and iv) as a result, segregation of GM and non-GM varieties is not likely to be an option in these systems. (nature.com)

The risks of gene-editing? (theecologist.org)
Acknowledgement of this challenge has led to theorizing various means to control or reverse gene drives, however these exist only as mathematical models and are accompanied by their own complex risks. (cban.ca)

Database, GeneCards Human Gene. (wikipedia.org)
If approved, the salmon would be the first ever GM animal allowed to enter the human food supply. (gmwatch.org)

Through knockout experiments, researchers found that mice without the NFIB gene have severely underdeveloped lungs. (wikipedia.org)

The staff's subsequent steps shall be to make sure their speculation by way of recreating identified examples of lateral gene switch, to research whether or not this ongoing procedure contributes to the diversities we apply between crop types. (clichetv.news)
Prof John Hillman, director of the Scottish Crop Research Institute, is quoted in an article in the obliging Scotsman newspaper attacking organic farming and hyping the benefits of GM and chemical agriculture. (gmwatch.org)

Nuclear factor 1 B-type is a protein that in humans is encoded by the NFIB gene. (wikipedia.org)
Eight dyskeratosis congenita genes ( DKC1 (dyskeratosis congenita 1), TERC (telomerase RNA component), TERT (telomerase reverse transcriptase), NOP10 (nucleolar protein 10), NHP2 , TINF2 (TERF1-interacting nuclear factor 2), TCAB1 and RTEL1 (regulation of telomere elongation helicase 1)) have already been identified, and their mutations account for ∼60% of all dyskeratosis congenita cases [ 1 ]. (ersjournals.com)
TTC triplet repeat expansion in an intron of the nuclear FXN gene, which encodes the essential mitochondrial protein frataxin ( 1 ). (frontiersin.org)

The current GM regulatory and oversight system is terribly flawed, putting the public health at risk. (wakeup-world.com)

Upon reviewing the research by EFSA, Independent Science News said that because the viral gene was not caught by biotech companies and government regulators, "this situation represents a complete and catastrophic system failure. (wakeup-world.com)
Gene technology is widely used in Australia: in agriculture, in research, in health and medicine, in education, and in industry. (ogtr.gov.au)
Organisations and individuals from across the scientific, breeding, farming, veterinary and input supply sectors have come together to express support for the potential role of new breeding technologies such as gene editing in delivering more sustainable, high-welfare UK livestock research and production. (nfuonline.com)
The research group Target Malaria (see below), funded by the Bill and Melinda Gates Foundation among others, aims to use gene drive mosquitoes to reduce the population of Anopheles gambiae mosquitoes, which transmit the parasite that causes malaria. (cban.ca)
The research group Target Malaria aims to use gene drive mosquitoes to reduce the population of Anopheles gambiae mosquitoes, which can transmit the parasite that causes malaria. (cban.ca)

Government agencies regulate GM foods  GM foods in the United States are required to be labeled only if the nutritional value is changed or a new allergen is introduced. (slideplayer.com)

Anatomy23

Organisms20

Diseases16

Chemicals and Drugs103

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Psychiatry and Psychology1

Phenomena and Processes31

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture16

Information Science5

Health Care4

Geographicals1

Crops25

Genetically11

Susceptibility genes2

GMOs9

Canola3

Office of the Ge1

20232

Novel genes2

Sequences5

Genomes5

Trait1

Africa5

Encode2

Grown1

Single gene5

Plants9

Organism's genome1

Mutations responsible2

Protein codi1

Antibiotic1

Wheat8

Species2

Organism1

Insects3

Pulmonary3

Kinase1

Specificity1

Interactions2

CRISPR4

Organisms3

Nucleotide1

Rice2

20211

Involve1

Commercially1

Tumor5

Maize1

Proteins2

Regulator1

Burkina Faso1

Soybean1

Pests1

Agricultural2

Inheritance3

Resistance5

Products4

Farmers1

Puts1

Horizontal4

Expression14

Complement2

Implications1

Freeze1

Varieties1

Risks2

Human2

Researchers1

Crop2

Nuclear3

Oversight1

Research5

Regulate1