ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 5, also know as ST3GAL5 belongs to the glycosyltransferase family 29 and localized to the Golgi apparatus. (prospecbio.com)
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A encoded by MGAT5 belongs to the glycosyltransferase family. (abbkine.com)
Cyclodextrin4
Cyclodextrin glycosyltransferase production by free cells of Bacillus circulans DF 9R in batch fermentation and by immobilized cells in a semi-continuous process. (uchile.cl)
Cyclodextrin glycosyltransferase (CGTase) catalyzes the starch conversion into cyclic or linear oligosaccharides, important industrial products. (uchile.cl)
Five kinds of enzymes could catalyze the AA-2G production, including α-amylase, α-glucosidase, sucrose phosphatase, α-isomaltosyl glucosaccharide-forming enzyme and cyclodextrin glycosyltransferase (EC 2.4.1.19, CGTase). (biomedcentral.com)
3. Rather, MY, Ara KZG, Nordberg Karlsson E, Adlercreutz P. ( 2015 ) Characterization of cyclodextrin glycosyltransferases (CGTases) and their application for synthesis of alkyl glycosides with oligomeric head group. (lu.se)
A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis. (ouhsc.edu)
This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. (unl.edu)
The enzyme is homologous to sucrose phosphate synthase, which catalyzes the penultimate step in sucrose synthesis. (unl.edu)
Sucrose synthases catalyze the synthesis of sucrose from UDP-glucose and fructose. (unl.edu)
In addition glycosyltransferases also catalyze the transfer of sugar moieties onto aglycons, which is of great relevance for the synthesis of many high value natural products. (heiderlab.de)
Together with glycosyltransferases, glycosidases form the major catalytic machinery for the synthesis and breakage of glycosidic bonds. (targetmol.com)
Enzyme4
In the next step, ColB, an NADP-dependent short-chain dehydrogenase-reductase enzyme, catalyzes the oxidation at C-4 and the removal of the hydroxyl group at C-6. (wikipedia.org)
An enzyme that catalyzes the reversible isomerization of D-mannose-6-phosphate to form D-fructose-6-phosphate, an important step in glycolysis. (lookformedical.com)
Schmid J, Heider D , Wendel NJ, Sperl N, Sieber V: Bacterial Glycosyltransferases: Challenges and opportunities of a highly diverse enzyme class toward tailoring natural products. (heiderlab.de)
The enzyme subclass of glycosyltransferases (EC 2.4) currently comprises 97 families as specified by CAZy classification. (heiderlab.de)
UGTs4
These are catalyzed by KAH (kaurenoic acid-13-hydroxylase) and four UGTs (UDP-glycosyltransferases) identified as UGT85C2, UGT74G1 and UGT76G1. (scialert.net)
UGTs) catalyze the transfer of glucuronic acid from UDP-glucuronic acid to endo- and xenobiotics in our body. (erksignal.com)
UGTs belong to the GT1 family of glycosyltransferases and many GT1s Cyclic nucleotide phosphodiesterase use a serine protease-like catalytic mechanism in which an Asp-His pair deprotonates a hydroxyl on the aglycone for nucleophilic attack on the sugar donor. (erksignal.com)
Biosynthesis4
The biosynthesis of colitose begins with ColE, a mannose-1-phosphate guanylyltransferase that catalyzes the addition of a GMP moiety to mannose, yielding GDP-mannose. (wikipedia.org)
Steviol glycoside biosynthesis pathway has sixteen steps catalyzed by different enzymes. (scialert.net)
These steps have been reported to be catalyzed by enzymes GGDPS (geranylgeranyl diphosphate synthase), CDPS (copalyl diphosphate synthase), KS (kaurene synthase) and KO (kaurene oxidase). (scialert.net)
A group of enzymes that catalyze an intramolecular transfer of a phosphate group. (lookformedical.com)
Enzymes that catalyze the transfer of mannose from a nucleoside diphosphate mannose to an acceptor molecule which is frequently another carbohydrate. (lookformedical.com)
glycans can't be cloned and glycosylation reactions are catalyzed by enzymes known as glycosyltransferases (GTFs) (Katrlik - digital rectal evaluation blood check (PSA level check) urine check (monitoring of irritation procedures in bladder) trans-rectal ultrasound to judge the quantity of prostate noninvasive dimension of urine stream - uroflowmetry and individual′s evaluation of the severe nature of LUTC. (scienceexhibitions.org)
The resulting product, GDP-L-colitose, is then incorporated into the O-antigen by glycosyltransferases and O-antigen processing proteins. (wikipedia.org)
On the biochemistry function, POGLUT2 can catalyze to transfer the glucose from UDP-glucose to a serine residue and specifically target extracellular epidermal growth factor (EGF) repeats of proteins such as Notch signaling members (NOTCH1 and NOTCH3) ( 9 , 10 ), thereby affecting Notch signaling pathway ( 11 ). (frontiersin.org)
Any of the enzymatically catalyzed modifications of the individual AMINO ACIDS of PROTEINS, and enzymatic cleavage or crosslinking of peptide chains that occur pre-translationally (on the amino acid component of AMINO ACYL TRNA), co-translationally (during the process of GENETIC TRANSLATION), or after translation is completed (POST-TRANSLATIONAL PROTEIN PROCESSING). (lookformedical.com)
Even when most glycosyltransferases are poorly explored, state of the art technologies, such as protein engineering, domain swapping or computational analysis strongly enhance our understanding and utilization of these very promising classes of proteins. (heiderlab.de)
Glycosylation1
Glycogenes and altered glycosylation patterns, including increased sialylation of O-glycans (2), core fucosylation (3), and glycosyltransferase expression levels (4), have been detected in various cancers. (vectorlabs.com)
Bacterial3
And identifying the gaffer at the bacterial glycosyltransferase assembly line could well be the first step towards a new drug against bacterial infections. (uea.ac.uk)
The arabinosylation of AG takes place on the periplasmic side of the plasma membrane catalyzed by membrane-associated decaprenyl phosphate arabinose-dependent glycosyltransferases (7). (sicollaborative.org)
Hydrolysis1
Glycoside hydrolases (also called glycosidases or glycosyl hydrolases) catalyze the hydrolysis of glycosidic bonds in complex sugars. (targetmol.com)
GlcNAc3
This structure consists of GlcNAc linked to a core β-mannose residue via a β1,4 linkage, catalyzed by N-acetylglucosaminyltransferase III (MGAT3). (vectorlabs.com)
The research team had previously reported a decrease in GlcNAc and the corresponding glycosyltransferase expression (MGAT3) during tumor-induced epithelial-to-mesenchymal transition (EMT) (6). (vectorlabs.com)
This step is followed by the attachment of a rhamnosyl residue from dTDP-Rha to the 3-position of GlcNAc in a reaction catalyzed by WbbL1 to form GL-2 (Dec-P-P-GlcNAc-Rha), the linker unit (Fig. 1). (sicollaborative.org)
Glycoprotein1
They catalyze the transfer of N-ACETYLNEURAMINIC ACID from CMP-N-ACETYLNEURAMINIC ACID to an acceptor, which is usually the terminal sugar residue of an oligosaccharide, a glycoprotein, or a glycolipid. (bvsalud.org)
Sialyltransferase2
ST6 β-galactoside α2,6-sialyltransferase (ST6GAL1) is a glycosyltransferase which is known to be upregulated in cancer. (uab.edu)
It acts as a master regulator of a cell by being the predominant sialyltransferase catalyzing the addition of a bulky negatively charged sialic acid to the galactose sugar in an α2,6-linkage. (uab.edu)
Molecules1
Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. (unl.edu)
Bacillus1
This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. (unl.edu)
Sugars1
Although the sugar is relatively rare, recent work with glycosyltransferases suggests that obscure sugars such as colitose can be incorporated into existing natural-product scaffolds, thereby constructing novel and potentially therapeutic compounds. (wikipedia.org)
Glycoside1
According to the double displacement mechanism, to increase the yield of glycoside products catalyzed by α -glucosidase, the affinity for glycosyl receptor in the deglycosylation process must be enhanced. (researchsquare.com)
The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. (unl.edu)
Addition2
It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. (abbkine.com)
Further, we confirmed that wciE encodes a glycosyltransferase that catalyzes the addition of the branching -D-Galp and that its inactivation in 33F strains results in the expression of the 33E capsule type. (cdc.gov)
Chains3
We know, for example, that the sugar chains are put together at a "cellular assembly line", where more than 7000 individual "workers", so-called glycosyltransferases, toil, each single one of them with a very specific task. (uea.ac.uk)
The tools the glycosyltransferase workers use to put together the various sugar chains are called sugar-nucleotides. (uea.ac.uk)
The peptidoglycan monomers are then polymerized on the outside surface by glycosyltransferases, which form the linear glycan chains, and transpeptidases, which catalyze the formation of peptide crosslinks. (ecmdb.ca)
Formation2
ST3GAL5 is a type II membrane protein which catalyzes the formation of GM3 with lactosylceramide as the substrate. (prospecbio.com)
The E. coli C-glycosyltransferase IroB catalyzes formation of a C-C bond between enterobactin and the glucose moiety of UDP-glucose, resulting in the production of mono-, di- and tri-glucosylated enterobactin (MGE, DGE, TGE). (concordia.ca)
Sugar3
To find out, we want to make specialist sugar-nucleotide tools which will only be used by a few glycosyltransferase workers - or maybe only by a single one of them! (uea.ac.uk)
We will make a lot of specialist sugar-nucleotides that are all slightly different from one another, to see if individual glycosyltransferases have a preference for a particular specialist sugar-nucleotide. (uea.ac.uk)
But whatever the result, this will help us identify those glycosyltransferase workers which carry out important tasks, and those which only add a sugar to the chain every now and then. (uea.ac.uk)
Higher1
Flavonol concentration was higher in RDI-1S berries due to the upregulation of the flavonol synthases and the flavonol-3- O -glycosyltransferases. (frontiersin.org)
Results1
These results provide a basis for tailoring an efficient glycosyltransferase. (figshare.com)
Type1
Herein, we characterize a newly discovered capsule type, 33E, that appears to have repeatedly emerged from vaccine type 33F via an inactivation mutation in the capsule glycosyltransferase gene, wciE. (cdc.gov)