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  • gene
  • Dear Netters I am looking for the GUS gene from which the glycosylation sites have been removed by site directed mutagenesis. (bio.net)
  • Once the screening test results prove suggestive of an N -glycosylation disorder, further biochemical studies on fibroblasts and/or gene sequencing are performed to establish the exact defect. (oncologynurseadvisor.com)
  • site
  • Chandler KB, Pompach P, Goldman R and Edwards N (2013) Exploring site‐specific N‐glycosylation microheterogeneity of haptoglobin using glycopeptide CID tandem mass spectra and glycan database search. (els.net)
  • comparative
  • Huffman JE et al (2014) Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological research. (springer.com)
  • analysis
  • At SGS, we have shaped our Glycosylation Analysis Service to meet the requirements of ICH 6QB, so you can be sure you are meeting regulatory expectations. (sgs.com)
  • Our experts are always at hand to give advice on what may be most appropriate for you, whether you are using glycosylation analysis for drug discovery or at any stage of the drug manufacturing process. (sgs.com)
  • half
  • Data show that nearly half of 239 glycosylation-associated genes (glycogenes) were significantly differentially expressed among neonatal and adult atrial and ventricular myocytes. (pnas.org)
  • chemical
  • Glycosylation (see also chemical glycosylation ) is the reaction in which a carbohydrate , i.e. a glycosyl donor , is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor ). (wikipedia.org)
  • data
  • Cooper CA, Gasteiger E and Packer NH (2001) GlycoMod - a software tool for determining glycosylation compositions from mass spectrometric data. (els.net)
  • shown
  • Glycosylation of Na v and K v subunits were shown to alter channel gating in isoform- and subunit-dependent manners ( 11 - 14 ). (pnas.org)
  • cancer
  • N‐ and O‐ linked glycosylation have been reported to be altered in cancer and implicated in all of the steps in the metastatic cascade. (els.net)