• Jeremy Luban, Aaron Lin, and Ted Diehl join the TWiV team to discuss their work on identifying a single amino acid change i n the Ebola virus glycoprotein from the West African outbreak that increases infectivity in human cells. (virology.ws)
  • Ebola glycoprotein, a previous featured structure , serves the same function to recognise host cells and internalise the virus. (ebi.ac.uk)
  • A conserved region in the gp120 glycoprotein that is involved in the metastable attachment of gp120 to CD4 has been identified and targeting of invariant region has been achieved with a broadly neutralising antibody, IgG1-b12. (wikipedia.org)
  • Because antibody-dependent cell-mediated cytotoxicity (ADCC) exists as an example of glycan function in glycoproteins, there have been many studies of glycan remodeling of antibodies. (go.jp)
  • and informatics tools used for identifying glycoproteins and characterizing the associated glycans. (springer.com)
  • Glycoproteins produced by cultured cells generally have heterogeneous glycans, so it is unclear which glycan is associated with the function of the glycoprotein. (go.jp)
  • The physiological function of the human P-glycoproteins encoded by the MDR1 and MDR3 (or MDR2) genes remains a matter of speculation. (nih.gov)
  • citation needed] Examples of glycoproteins in the immune system are: molecules such as antibodies (immunoglobulins), which interact directly with antigens. (wikipedia.org)
  • Multidrug resistance mediated by P-glycoproteins. (nih.gov)
  • Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology. (fpnotebook.com)
  • Babies receive glycoproteins from their mothers' milk that hinder bacteria, viruses and even cancer cells. (livestrong.com)
  • Cancer cells that have too much p-glycoprotein may not be killed by anticancer drugs. (fpnotebook.com)
  • To solve this problem, transgenic cells have been developed to produce homogeneous glycoproteins through control of the biosynthetic pathway, but it is difficult to prepare glycoproteins with various kinds of homogeneous glycan by using this approach. (go.jp)
  • these cells have a strong positive reaction for the MUC1 glycoprotein. (drbicuspid.com)
  • The structure and function of P-glycoprotein genes has been studied in mammals and in several lower eukaryotes. (nih.gov)
  • Moreover, because glycoproteins are heterogeneous, it is difficult to analyze their structure by X-ray crystal diffraction or NMR measurement. (go.jp)
  • This latter fruit gains its name through its ability to turn sour foods sweet-tasting, and vice versa -- an effect of a glycoprotein that coats the tongue and alters the tastebuds for anywhere from 30 minutes to one hour after you eat it. (livestrong.com)
  • Miraculin, is a glycoprotein extracted from Synsepalum dulcificum a berry which alters human tongue receptors to recognize sour foods as sweet. (wikipedia.org)
  • structural glycoproteins, which occur in connective tissue . (wikipedia.org)
  • For those who want to ensure they are receiving glycoproteins in their diet, you can find a number of foods packed with these organic compounds. (livestrong.com)
  • Solutions of glycoproteins usually exhibit high viscosity, an observation explaining the highly viscous character of egg white, which is composed largely of the glycoprotein ovalbumin. (infoplease.com)
  • Echinacea and turmeric contain high levels of glycoproteins, as does the miracle fruit, or miracle berry. (livestrong.com)
  • Soluble glycoproteins often show a high viscosity, for example, in egg white and blood plasma. (wikipedia.org)
  • Many people make sure to include glycoproteins in their diet as a way to boost their immune systems and prevent or delay the spread of cancer. (livestrong.com)
  • Many secreted glycoproteins are inserted into the outer membrane of the cell. (blogspot.com)
  • P-glycoproteins are thought to act as ATP-dependent drug efflux pumps, actively extruding a range of structurally different, hydrophobic drugs from the cell. (nih.gov)