• Tissue, cells or virus corresponding to Human coronavirus SARS-CoV-2 Spike Glycoprotein S1. (abcam.com)
  • Recombinant Anti-SARS-CoV-2 Spike Glycoprotein S1 antibody (ab273073) is a Human IgG1 Recombinant version of CR3022 for research use only. (abcam.com)
  • Our analysis of the spike glycoprotein of 2019-nCoV revealed several interesting findings: First, we identified 4 unique inserts in the 2019-nCoV spike glycoprotein that are not present in any other coronavirus reported till date. (healthimpactnews.com)
  • Further, 3D modelling suggests that at least 3 of the unique inserts which are non-contiguous in the primary protein sequence of the 2019-nCoV spike glycoprotein converge to constitute the key components of the receptor binding site. (healthimpactnews.com)
  • Search, find, compare suppliers for anti-SARS-CoV/SARS-CoV-2 Spike Glycoprotein RBD antibody, protein, ELISA kits. (linscottsdirectory.com)
  • Platelet Glycoprotein GPIIb-IIIa Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • This graph shows the total number of publications written about "Platelet Glycoprotein GPIIb-IIIa Complex" by people in Harvard Catalyst Profiles by year, and whether "Platelet Glycoprotein GPIIb-IIIa Complex" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Platelet Glycoprotein GPIIb-IIIa Complex" by people in Profiles. (harvard.edu)
  • Clopidogrel selectively inhibits adenosine diphosphate (ADP) binding to platelet receptors and subsequent ADP-mediated activation of glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation. (medscape.com)
  • Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury . (online-medical-dictionary.org)
  • Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. (harvard.edu)
  • Glycoprotein VI deficiency can be caused by mutations in the GP6 gene, which provides instructions for making a protein called glycoprotein VI (GPVI). (medlineplus.gov)
  • As a result, there is a shortage (deficiency) of functional GPVI protein on the surface of platelets, which leads to bleeding problems characteristic of glycoprotein VI deficiency. (medlineplus.gov)
  • The herpes simplex virus type 1 (HSV-1) glycoprotein N (gN/UL49.5) is a type I transmembrane protein conserved throughout the herpesvirus family. (mdpi.com)
  • In studies investigating the impacts of retaining the E3 glycoprotein on mature virus outside of a host cell, we found this retention of E3 decreases receptor-mediated entry of cell targets that can be rescued on cells containing heparan sulfate suggesting viruses containing E3 on mature envelopes can utilize the E3 protein as an attachment factor. (purdue.edu)
  • The results of Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses suggested that glycoproteins are involved in various functions, such as the regulation of cell growth, cell adhesion, cellular component organization and protein binding, as well as multiple pathways, including p53, Notch and mTOR signaling pathways. (spandidos-publications.com)
  • The protein microfibril-associated glycoprotein (MAGP)-1 constitutes a crucial extracellular matrix protein. (cun.es)
  • Membrane glycoproteins are membrane proteins which play important roles in cell recognition. (wikipedia.org)
  • The drug efflux pump P-glycoprotein (Pgp) can be an additional locus contributing to these drug interactions because there is overlap in drugs that are substrates for both proteins. (nih.gov)
  • Exploratory Use of Glycoprotein IIb/IIIa Inhibition in Prevention of Blalock-Taussig Shunt Thrombosis. (harvard.edu)
  • In this study, we further characterize a mutant P-glycoprotein (P-gp) that has a deletion of Phe 335 and is resistant to inhibition by cyclosporins. (aspetjournals.org)
  • Arlen M, Arlen P, Tsang A, Wang X, Gupta R. The Therapeutic Value of Monoclonal Antibodies Directed Against Immunogenic Tumor Glycoproteins. (jcancer.org)
  • The nine E-glycoprotein-reactive monoclonal antibodies also neutralized dengue 2 virus in a plaque reduction assay. (ajtmh.org)
  • The protective monoclonal antibodies were directed against viral determinants that fell into at least three spatially separate families of epitopes on E-glycoprotein, the antigenicities of which were preserved after heat/detergent denaturation. (ajtmh.org)
  • Rational Laboratory Diagnostics of Antiphospholipid Antibodies: Anti-Cardiolipin, Anti-β2-Glycoprotein I, Anti-Prothrombin and Anti-Annexin V Antibodies. (ncbcs.org)
  • A attainable co-appearance of anticardiolipin (aCL), anti-β2-glycoprotein I (anti-β2-GPI), anti-prothrombin (aPT) and anti-annexin V (aANXV) antibodies of IgG, IgM and IgA class have been studied in 58 sufferers with SLE alone and 32 sufferers APS within the view of rational laboratory diagnostics. (ncbcs.org)
  • Anti-α1-acid glycoprotein antibodies react with antigen in the sample to form an antigen/antibody complex. (cdc.gov)
  • Extensins are members of the cell wall hydroxyproline-rich glycoprotein (HRGP) superfamily that form covalently cross-linked networks in primary cell walls. (umass.edu)
  • The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed. (nih.gov)
  • 1997). "Isolated P-selectin glycoprotein ligand-1 dynamic adhesion to P- and E-selectin" . (wikidoc.org)
  • Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region. (nih.gov)
  • The organization of the SELPLG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters. (wikidoc.org)
  • The presence in orange juice of compounds that specifically inhibit the P-glycoprotein (P-gp) drug efflux transporter, but not the cytochrome P450 (CYP) isozyme CYP3A4, was investigated. (aspetjournals.org)
  • P-selectin glycoprotein ligand-1 ( PSGL-1 ) is a glycoprotein found on white blood cells and endothelial cells that binds to P-selectin (P stands for platelet ), which is one of a family of selectins that includes E-selectin (endothelial) and L-selectin (leukocyte). (wikidoc.org)
  • Boronoisophthalic acid as a novel affinity ligand for the selective capture and release of glycoproteins near physiological pH. (bvsalud.org)
  • Here in this study, we used 5-boronoisophthlic acid as a novel affinity ligand for the selective capture and release of glycoproteins . (bvsalud.org)
  • 2015. Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial. (who.int)
  • MUC glycoproteins: Potential biomarkers and molecular targets for cancer therapy. (amrita.edu)
  • Home Publications MUC glycoproteins: Potential biomarkers and molecular targets for cancer therapy. (amrita.edu)
  • Hermans C, Wittevrongel C, Thys C, Smethurst PA, Van Geet C, Freson K. A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder. (medlineplus.gov)
  • Prohibited glycoprotein hormones such as ESA, hCG, FSH etc. are currently tested by immunological methods, and the decision is made by immuno-blotting electrophoresis or by comparing concentration with the applicable threshold. (wada-ama.org)
  • Prohibited glycoprotein hormones are currently tested by immunological methods with the result evaluation using the applicable threshold or by comparing the isoform profile with that of the reference standard as no procedure yet available to identify their origins. (wada-ama.org)
  • The glycoprotein contains unique tandem repeats of eight amino acids, of which two threonine residues are probably glycosylated by N -acetyl-d-galactosamine (GalNAc). (figshare.com)
  • The pKa value of 5-boronoisophthalic acid is investigated to be 7.8 which is just closed to physiological pH and is ideally suitable for the fast binding and elution kinetics of glycoproteins to avoid their degradation and deactivation. (bvsalud.org)
  • Thus, findings of our 1st year project supported the possibility of origin specific detection of glycoproteins by lectin specific extraction coupled to a normal immunoassay instruments that commonly used by all WADA laboratories. (wada-ama.org)
  • Kit contains all enzymes and reagents needed to remove all N-linked, all simple O-linked, and virtually all-complex O-linked oligosaccharides from glycoproteins in a single reaction at neutral pH. (sigmaaldrich.com)
  • Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin . (online-medical-dictionary.org)
  • Platelets play a primary role in this process, interacting with subendothelium-bound von Willebrand factor (vWf) via the membrane glycoprotein (GP) Ib complex. (medscape.com)
  • The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. (nih.gov)
  • Our first year results represented that recombinant and human glycoprotein hormone can be isolated by stereo specific lectin-glycane interactions, and the recombinant fraction does not show any human type glycane specific lectin interactions. (wada-ama.org)
  • Glycoproteins from human show a strong lectin-glycan interaction with certain lectins whereas those expressed in CHO-cell lines do not show any interaction with the selected lectins. (wada-ama.org)
  • Finally, the boronic-based affinity tip is successfully applied to selectively capture the glycoproteins from the human milk sample, especially lactoferrin which is highly important in dairy manufacture. (bvsalud.org)
  • Without GPVI binding to collagen, platelets cannot come together efficiently to form a clot, leading to the bleeding problems associated with glycoprotein VI deficiency. (medlineplus.gov)
  • Together, these data suggest that the E3 glycoprotein protects the fusion region of E1 on budded, mature virus dependent on the pH of the extracellular environment. (purdue.edu)
  • Identification of the Abundant Hydroxyproline-Rich Glycoproteins in th" by Yuning Chen, Dening Ye et al. (umass.edu)
  • Some other possible markers to indicate origin of glycoprotein were evaluated. (wada-ama.org)
  • Aims The aim of this observational study was to report the distribution of glycoprotein B (gB) genotypes in the eyes of cytomegalovirus (CMV) positive patients with Posner-Schlossman syndrome (PSS), and to investigate their clinical characteristics and outcomes. (bmj.com)
  • The aim of the present study was to elucidate the potential diagnostic value of urinary N‑glycoprotein in patients with IgA nephropathy (IgAN) using mass spectrometry (MS). All procedures were performed between June 2021 and June 2023 at Guangan People's Hospital (Guangan, China). (spandidos-publications.com)
  • 2, a total of 11 upregulated and 22 downregulated glycoproteins in patients with IgAN were identified. (spandidos-publications.com)
  • In conclusion, MS‑based proteomics of urinary glycoproteins may be an alternative option for diagnosing patients with IgAN. (spandidos-publications.com)
  • With provisional use of glycoprotein IIb/IIIa inhibitor (GP IIb/IIIa inhibitor), bivalirudin is indicated for use as an anticoagulant in patients undergoing PCI. (medscape.com)
  • Chez les patients hypertendus, le taux de mortalité était plus élevé uniquement chez les patients admis pour un infarctus du myocarde avec sus-décalage du segment ST. Après ajustement des résultats en fonction des variables de référence, l'hypertension s'est révélé être un facteur prédictif indépendant de l'insuffisance cardiaque (OR = 1,31) et de l'accident vasculaire cérébral (OR = 2,47). (who.int)
  • Cloning and expression of a new pregnancy-specific beta 1-glycoprotein member. (nih.gov)
  • talks.cam : How does the African trypanosome control expression of its Variant Surface Glycoprotein coat? (cam.ac.uk)
  • But often, these boronate affinity materials are stuck to some serious issues like high binding pH and weak affinity, especially in the case of glycoproteins . (bvsalud.org)
  • This boronic acid -based affinity tip exhibits binding constants for model glycoproteins in the range of 10-6-10-7 M, binding capacities in the range of 0.662 µM/g, and selectivity up to 11000 (HRP to BSA) under optimized extraction conditions. (bvsalud.org)
  • Addgene: Improving cell-free glycoprotein synthesis by characterizing and enriching native membrane vesicles. (addgene.org)
  • Retroviral Envelope Glycoproteins: Structure and Evolution. (tufts.edu)
  • Membrane glycoproteins found in high concentrations on iron-utilizing cells. (bvsalud.org)
  • Among the most promising filovirus vaccines under development is a system based on recombinant vesicular stomatitis virus (rVSV) that expresses an individual filovirus glycoprotein (GP) in place of the VSV glycoprotein (G). The main concern with all replication-competent vaccines, including the rVSV filovirus GP vectors, is their safety. (nih.gov)
  • Furthermore, these inserts are the same as certain glycoproteins in the HIV-1 virus. (healthimpactnews.com)
  • It is composed of three glycoproteins with various functions during fertilization and preimplantation development. (nih.gov)
  • Glycoprotein VI deficiency is a bleeding disorder associated with a decreased ability to form blood clots. (medlineplus.gov)
  • Because people with glycoprotein VI deficiency cannot form blood clots normally, they have an increased risk of nosebleeds (epistaxis) and may experience abnormally heavy or prolonged bleeding following minor injury or surgery. (medlineplus.gov)
  • Mucins belong to a heterogeneous group of large O-glycoproteins that can be either secreted or membrane-bound. (amrita.edu)
  • Genetically manufactured glycoprotein has the unique isoform profile and the heterogeneity can sometimes cause in interpretation difficulties. (wada-ama.org)