• GYPA / CD235a / Glycophorin A specific IgG was purified by Human GYPA / CD235a / Glycophorin A affinity chromatography. (novoprolabs.com)
  • The HIR2 antibody reacts with a common epitope of glycophorin A (CD235a) and glycophorin B (CD235b). (biolegend.com)
  • Ultrastructure of a transmembrane glycoprotein, glycophorin A. Tissue & Cell. (bdbiosciences.com)
  • Rh null cells have altered expression of glycophorin B and LW glycoprotein. (lu.se)
  • LEL binds well to glycophorin and Tamm-Horsfall glycoprotein and has been used effectively to label vascular endothelium in rodents. (vectorlabs.com)
  • The Rh antigens appear to exist as a multisubunit complex of CD47 (MIM 601028), LW (MIM 111250), glycophorin B (MIM 111740), and play a critical role in the Rh50 glycoprotein. (novusbio.com)
  • Coordinate glycosylation and cell surface expression of glycophorin A during normal human erythropoiesis. (bdbiosciences.com)
  • After accounting for known malaria risky loci and other potential confounders such as parasite diversity, they narrowed in on a suspicious new chromosome 4 site falling between the FREM3 gene and the GYPE, GYPB, and GYPA genes, which code for glycophorin proteins expressed in the red blood cell membrane. (genomeweb.com)
  • Anti-glycophorin A reacts with a major sialoglycoprotein present on the human erythrocyte membrane. (bdbiosciences.com)
  • Expression of the major sialoglycoprotein (glycophorin) on erythroid cells in human bone marrow. (bdbiosciences.com)
  • Glycophorin A is the major sialoglycoprotein expressed on red blood cell membrane, and erythroid precursors. (biolegend.com)
  • Anti-Glycophorin A is useful for understanding erythroid cell development and identifying erythroid leukemias. (abeomics.com)
  • Description: The HIR2 monoclonal antibody reacts with human glycophorin A, a sialoglycoprotein expressed by erythroid precursors and mature circulating red cells. (cytekbio.com)
  • Glycophorin A shares strong homology with glycophorin B. The HIR2 antibody recognizes human RBCs and erythroid precursors and is useful in erythroid cell development studies. (biolegend.com)
  • A glycophorin is a sialoglycoprotein of the membrane of a red blood cell. (wikipedia.org)
  • These have been named glycophorin A, B, C, and D in order of the quantity present in the membrane, gylycophorin A being the most and glycophorin D the least common. (wikipedia.org)
  • In the erythrocyte glycophorin C makes up ~4% of the membrane sialoglycoproteins . (wikidoc.org)
  • AE1 is also activated by interaction with glycophorin which also functions to target it to the plasma membrane ( Young and Tanner, 2003 ). (tcdb.org)
  • Moreover, we show that Heminecrolysin efficiently binds to erythrocyte's membrane and provokes phosphatidylserine (PS) translocation without cleavage of glycophorin A, suggesting that, unlike spider's PLDs, complement was activated only via the classical pathway. (hal.science)
  • Identification of the major human sialoglycoprotein from red cells, glycophorin AM, as the receptor for Escherichia coli IH 11165 and characterization of the receptor site. (bdbiosciences.com)
  • Glycophorin as a receptor for sendai virus. (bdbiosciences.com)
  • They chose the model helical dimer glycophorin A and the transmembrane region of the TrkA neurotrophin receptor, which have a similar structure but different amino acid sequences. (h-its.org)
  • Vaccines that target parasite proteins involved in the dominant glycophorin pathway, but do not block the CR1 pathway, may cause proliferation of parasites that rely on the CR1 pathway for infection. (medicalxpress.com)
  • NEW YORK (GenomeWeb) - The severity of malaria infections caused by Plasmodium falciparum in African children appears to be partly influenced by a locus falling near genes coding for glycophorin proteins involved in red blood cell invasion. (genomeweb.com)
  • The replaced amino acids were located in a refined 3-dimensional computer model of the HAV protomer ( 11 ), and their relative distances to residues 1102, 1171 and 1176, constituents of the immunodominant site ( 12 ), and to residue 1221, constituent of the glycophorin A binding site epitope ( 13 ), were used as markers of the potential antibody-escaping phenotype. (cdc.gov)
  • Glycophorin A is a transmembrane dimeric complex of 31 kilodaltons (kd) with its caboxyterminal ends extending into the cytoplasm of the red cell. (bdbiosciences.com)
  • Despite the similar names glycophorin C and D are unrelated to the other three glycophorins which encoded on chromosome 4 at location 4q28-q31. (wikidoc.org)
  • Glycophorin A (GPA) and Glycophorin B (GPB) are erythrocyte blood group determinants that minimize erythrocyte aggregation during the circulation of blood. (abeomics.com)
  • Benting J, Mattei D, Lingelbach K. Brefeldin A inhibits transport of the glycophorin-binding protein from Plasmodium falciparum into the host erythrocyte. (huji.ac.il)
  • Mature, non-nucleated red blood cells are characteristically glycophorin A positive, but CD45 and CD71 negative. (biolegend.com)
  • Bone marrow samples from C57BL/B6 mice and one healthy donor were analyzed using traditional two-marker (CD71 and glycophorin A) flow cytometry analysis. (biomedcentral.com)
  • Erythrocytes deficiency in glycophorin resist invasion by the malarial parasite Plasmodium falciparum. (ox.ac.uk)
  • The following four human genes encode glycophorin proteins: Glycophorin A Glycophorin B Glycophorin C Glycophorin E Glycophorin D is now known to be a variant of Glycophorin C. Leffler EM, Band G, Busby GB, Kivinen K, Le QS, Clarke GM, et al. (wikipedia.org)
  • Glycophorin A was the most affected protein in sickle RBCs by this ERK1/2 pathway, which contained 12 unique phosphorylated peptides, suggesting that in addition to its effect on sickle RBC adhesion, increased glycophorin A phosphorylation via the ERK1/2 pathway may also affect glycophorin A interactions with band 3, which could result in decreases in both anion transport by band 3 and band 3 trafficking. (duke.edu)
  • At least two P. falciparum proteins bind host blood cells via interactions with the glycophorin proteins Glycophorin A and Glycophorin B, the team noted, consistent with a potential role for the glycophorin locus in helping to dodge severe malaria infection. (genomeweb.com)
  • or if the host were to be vaccinated with a vaccine that blocks the glycophorin pathway. (medicalxpress.com)
  • Originally it was thought that glycophorin C and D were the result of a gene duplication event but it was only later realised that they were encoded by the same gene. (wikidoc.org)
  • Glycophorin C (GPC) is a single polypeptide chain of 128 amino acids and is encoded by a gene on the long arm of chromosome 2 (2q14-q21). (wikidoc.org)
  • In melanocytic cells Glycophorin C gene expression may be regulated by MITF . (wikidoc.org)
  • A fifth (glycophorin E) has been identified within the human genome but cannot easily be detected on routine gel staining. (wikipedia.org)
  • CD34+ megakaryoblastic leukaemic cells are CD38-, but CD61+ and glycophorin A+: improved criteria for diagnosis of AML-M7? (bdbiosciences.com)
  • Ultrathin Polydopamine Films with Phospholipid Nanodiscs Containing a Glycophorin A Domain. (mpg.de)
  • A glycophorin is a sialoglycoprotein of the membrane of a red blood cell. (wikipedia.org)
  • EBS-CD-059 reacts with a 39 kDa sialoglycoprotein known as glycophorin A, present on red cells and erythroid precursor cells. (progen.com)
  • The replaced amino acids were located in a refined 3-dimensional computer model of the HAV protomer ( 11 ), and their relative distances to residues 1102, 1171 and 1176, constituents of the immunodominant site ( 12 ), and to residue 1221, constituent of the glycophorin A binding site epitope ( 13 ), were used as markers of the potential antibody-escaping phenotype. (cdc.gov)
  • The TER-119 antibody specifically binds to a 52 kDa molecule associated with glycophorin A on cells of the erythroid lineage in embryonic yolk sac, fetal liver, newborn liver, adult bone marrow, adult peripheral blood, and adult lymphoid organs. (bdbiosciences.com)
  • The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage. (bdbiosciences.com)
  • The following four human genes encode glycophorin proteins: Glycophorin A Glycophorin B Glycophorin C Glycophorin E Glycophorin D is now known to be a variant of Glycophorin C. Leffler EM, Band G, Busby GB, Kivinen K, Le QS, Clarke GM, et al. (wikipedia.org)
  • Helix-helix interactions in membrane proteins: coarse-grained simulations of glycophorin a helix dimerization. (ox.ac.uk)
  • However, some altered AE1 proteins cannot be helped by glycophorin A and are not trafficked to red blood cell membranes. (medlineplus.gov)
  • An uncommon variant glycophorin expressing protease-resistant M antigen encoded by the GYP B -E(2-4)- B hybrid gene. (tbdb.org)
  • We investigated an uncommon glycophorin molecule with protease-resistant M antigen. (tbdb.org)
  • 12. Interaction between glycophorin and ganglioside GM1 on liposomal membranes. (nih.gov)
  • This paper describes four assays that detect somatic gene mutations in humans: the hypoxanthine-guanine phosphoribosyl transferase assay, the glycophorin A assay, the HLA-A assay, and the sickle cell hemoglobin assay. (nih.gov)
  • Reactivity with glycophorin M and N was determined by hemagglutination assay (Mertens et al. (absoluteantibody.com)
  • This glycophorin is predicted to be a 59 amino acids polypeptide encoded by the novel GYPB-E(2-4)-B hybrid gene. (tbdb.org)
  • LEL binds well to glycophorin and Tamm-Horsfall glycoprotein and has been used effectively to label vascular endothelium in rodents. (vectorlabs.com)
  • A big structural rearrangement and hybrid glycophorin variant, referred to as Dantu , which was recognized in East African populations, has been linked with a 40% discount in threat for extreme malaria. (tbdb.org)
  • Serological assessments and immunoblotting revealed that 103 of the 193 009 people (0ยท0534%) expressed protease-resistant M-active glycophorin having a molecular weight of 20 kDa. (tbdb.org)
  • Providing a mucin like coat, glycophorin may play a role in preventing red cell aggregation in the circulation. (progen.com)
  • Glycophorin A is the carrier of blood group M and N specificities, while glycophorin B carries S and U specificities. (progen.com)