ProteinsBoric acidReceptorsWeak acidsOligomerCationicCalciumPreferentiallyGenesHydrochloricDegradationPeptideCovalentNucleic acidMammalianMetabolicUptakeExtracellularPhosphodiesterAccumulationSpeciesFatty acidCellularMolecularAbbreviationsAqueousProteinEnzymeDifferHydrogen ionsDefinitionsFunctionMembraneCellFoundReactionsSubstanceTransportContentProductionCellsActiveWaterAdditionExamplesStudies
Proteins1
- Variations in the amino acids are reflected by small conformational changes in the tertiary structure that contribute to the broad range of biological activities in these proteins. (frontiersin.org)
Boric acid3
- Strong acids and some concentrated weak acids are corrosive , but there are exceptions such as carboranes and boric acid . (alchetron.com)
- Inorganic or organic salts and esters of boric acid. (lookformedical.com)
- Inorganic and organic derivatives of boric acid either B(OH)3 or, preferably H3BO3. (lookformedical.com)
Receptors3
- Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its intracellular signaling. (lookformedical.com)
- An agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores. (nih.gov)
- After transcription problem and death, the AHR prostaglandin involves to the acid, occurs from the development addition, domains with the acid power uridylyltransferase primary proximity( ARNT) and has cell collagens via containing to mitotic survival outcomes( XREs) in their page receptors. (familie-vos.de)
Weak acids1
- Strong acids are those that are completely ionized in body fluids, and weak acids are those that are incompletely ionized in body fluids. (medscape.com)
Oligomer2
- According to the methods, a mixture of lipids containing a protonatable or deprotonatable lipid, for example an amino lipid and a lipid such as a PEG- or Polyamide oligomer-modified lipid is combined with a buffered aqueous solution of a charged therapeutic agent, for example polyanionic nucleic acids, to produce particles in which the therapeutic agent is encapsulated in a lipid vesicle. (justia.com)
- Deng, 2006), and that it is to the 5' place of the transcription arrest without signaling on the intracellular oligomer structure. (familie-vos.de)
Cationic2
- Defensins are small cationic peptides of 45-54 amino acid residues with a conserved signature of cysteines, which can form three to four disulfide bridges. (frontiersin.org)
- Among the transporters identified, we characterized the cationic amino acid transporter SLC7A3 as a gene that, when up-regulated, overcame low availability of arginine and lysine by increasing their uptake, whereas SLC7A5 was able to sustain cellular fitness upon deprivation of several neutral amino acids. (life-science-alliance.org)
Calcium2
- These N-acylglycines have been detected in the CNS in mammals and are linked to several important biological roles including antinociception, anti-inflammation, proliferative control, intracellular calcium mobilization, insulin release, body temperature regulation, locomotion, nitric oxide production in sensory neurons, and skin aging. (avantilipids.com)
- Acids form aqueous solutions with a sour taste, can turn blue litmus red, and react with bases and certain metals (like calcium ) to form salts. (alchetron.com)
Preferentially2
- A download Hanging Sam: A Military Biography of General Samuel T. Williams: From Pancho Villa to of residues are experienced regulated for the high 3-phosphate by which SP1 assemblies present to connected formation phagosome by UCP1 in transmembrane C1q-mediated fusion momenta, and preferentially by the intracellular genes as Once. (evakoch.com)
- This amino acid was demonstrated to be preferentially transported into BHK2l -C13 cells via a relatively low affinity, high capacity active transport system of broad specificity. (docksci.com)
Genes1
- In the chicken (Gallus gallus), the 161-amino acid vasotocin-neurophysin VT preprohormone is encoded by the gene AVP, which is considered homologous to the mammalian genes encoding arginine vasopressin. (wikipedia.org)
Hydrochloric2
- Common aqueous acids include hydrochloric acid (a solution of hydrogen chloride which is found in gastric acid in the stomach and activates digestive enzymes ), acetic acid (vinegar is a dilute aqueous solution of this liquid), sulfuric acid (used in car batteries), and citric acid (found in citrus fruits). (alchetron.com)
- Hydrochloric acid (HCl) is considered a strong acid because it is present only in a completely ionized form in the body, whereas carbonic acid (H 2 CO 3 ) is a weak acid because it is ionized incompletely, and, at equilibrium, all three reactants are present in body fluids. (medscape.com)
Degradation2
- This problem has been partially overcome by chemical modifications which reduce serum or intracellular degradation. (justia.com)
- An progenitor of endothelial degradation in the Emergency Department: differ cytokine acids Differential? (familie-vos.de)
Peptide1
- Removal of the 19-amino acid N-terminal signal peptide generates the prohormone, which is hydrolysed to AVT (derived from amino acids 20-28) and neurophysin VT (derived from amino acids 32-161). (wikipedia.org)
Covalent3
- An acid is a molecule or ion capable of donating a hydron ( proton or hydrogen ion H + ), or, alternatively, capable of forming a covalent bond with an electron pair (a Lewis acid). (alchetron.com)
- The second category of acids are Lewis acids , which form a covalent bond with an electron pair. (alchetron.com)
- However, hydrogen chloride , acetic acid, and most other Brønsted-Lowry acids cannot form a covalent bond with an electron pair and are therefore not Lewis acids. (alchetron.com)
Nucleic acid2
- Methods for the preparation of a lipid-nucleic acid composition are provided. (justia.com)
- This invention relates to compositions comprising a combination of a lipid and a therapeutic agent, particularly to lipid-nucleic acid compositions, for in vivo therapeutic use. (justia.com)
Mammalian3
- Amino acids constitute one of the largest and most diverse groups of compounds commonly concentrated by active transport, and their uptake has been studied in a wide variety of microbial and mammalian systems. (docksci.com)
- Considerable progress has been made in the characterisation of the various amino acid transport systems in bacteria and fungi, but the number and specificity of similar transport systems in mammalian cells is less clear. (docksci.com)
- have been carried out to determine the characteristics of the active transport of neutral amino acids by either isolated mammalian cells or cells in culture. (docksci.com)
Metabolic3
- Nevertheless, the accumulation of intracellular proline against butanol stress required a metabolic conversion of glutamate through the specific biosynthetic ProB-ProA-ProI route. (biomedcentral.com)
- One-by-one depletion of 13 amino acids required for cell proliferation enabled gain-of-function genetic screens using a SLC-focused CRISPR/Cas9-based transcriptional activation approach to uncover transporters relieving cells from growth-limiting metabolic bottlenecks. (life-science-alliance.org)
- Sherman and Fyfe 1990) and signaling of the neutral fluid to the active Dephosphorylation or metabolic transcription DNA( Bushman et al. (familie-vos.de)
Uptake3
- Kinetic studies of the inhibition of L-alanine uptake also indicated the presence of a second neutral amino acid transport system capable of transporting this amino acid. (docksci.com)
- 68) via uptake systems specific for single amino acids or groups of structurally related amino acids. (docksci.com)
- Uptake assay procedure Amino acid uptake was examined using a modification of the method described by Hatanaka et al. (docksci.com)
Extracellular1
- I-FABP) and bovine heart fatty acid-binding pro- tissues and in intracellular as well as extracellular tein (H-FABP). (lu.se)
Phosphodiester1
- No clinical assessment currently employs the basic phosphodiester chemistry found in natural nucleic acids, because of these and other known problems. (justia.com)
Accumulation1
- Detection of intracellular proline and glutamate accumulation, as well as glutamate transient conversion during butanol exposure confirmed their necessity, especially proline, for cellular butanol tolerance. (biomedcentral.com)
Species3
- N-acyl glycines are glycine conjugates of acyl-CoA species. (avantilipids.com)
- Lewis considered this as a generalization of the Brønsted definition, so that an acid is a chemical species that accepts electron pairs either directly or by releasing protons (H + ) into the solution, which then accept electron pairs. (alchetron.com)
- While the method was invented to separate neutral species, it can also be applied to charged molecules such as small peptides. (lookformedical.com)
Fatty acid3
- The analysis of acylglycines is important for the diagnosis of inherited disorders of mitochondrial fatty acid beta-oxidation. (avantilipids.com)
- Goethe-Universita¨t, DE-60439 tein (I-LBP) and intestinal fatty acid-binding protein (I-FABP). (lu.se)
- I-LBP, ileal lipid-binding to the aqueous solubility of the fatty acid. (lu.se)
Cellular2
- These are the ' zinc-binding cellular acid ' sugar and the ' genome resulting ' history. (evakoch.com)
- During cellular nitrosative stress, the production of intracellular GSNO might channel signaling responses to form protein-mixed disulfide that can regulate intracellular function. (lookformedical.com)
Molecular2
- They were characterized as a new member of the thionine family due to their similarity in molecular mass, amino acid sequence and number of cysteines. (frontiersin.org)
- Examples include molecular substances such as HCl and acetic acid. (alchetron.com)
Abbreviations1
- The current MCAT regularly has questions which require previous knowledge of the structures, features (including changes in charge with pH), 3- and 1-letter abbreviations of the 20 common protein-generating amino acids, etc. (mcat-prep.com)
Aqueous4
- In the special case of aqueous solutions , proton donors form the hydronium ion H 3 O + and are known as Arrhenius acids. (alchetron.com)
- Aqueous Arrhenius acids have characteristic properties which provide a practical description of an acid. (alchetron.com)
- An aqueous solution of an acid has a pH less than 7 and is colloquially also referred to as 'acid' (as in 'dissolved in acid'), while the strict definition refers only to the solute. (alchetron.com)
- Most acids encountered in everyday life are aqueous solutions, or can be dissolved in water, so the Arrhenius and Brønsted-Lowry definitions are the most relevant. (alchetron.com)
Protein2
- 1 L/d of drinking water was associated with concurrent changes in carbohydrate, protein, lipid, and micronutrient metabolism, a metabolomic pattern of carbohydrate oxidation via the tricarboxylic acid (TCA) cycle, instead of glycolysis to lactate, and a reduction of chronic disease risk factors in Week 6. (ppexmed.com)
- for example, H-FABP makes up 3% of the plasmic intracellular LBPs from three different cytoplasmic protein content in rat heart. (lu.se)
Enzyme1
- L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme. (medchemexpress.com)
Differ1
- they differ from the vasopressin-like peptides in having a neutral amino acid in place of a basic amino acid at position 8. (wikipedia.org)
Hydrogen ions1
- An acid is a substance that can donate hydrogen ions (H + ). A base is a substance that can accept H + ions. (medscape.com)
Definitions3
- Modern definitions are concerned with the fundamental chemical reactions common to all acids. (alchetron.com)
- Hydronium ions are acids according to all three definitions. (alchetron.com)
- Understanding the regulation of acid-base balance requires appreciation of the fundamental definitions and principles underlying this complex physiologic process. (medscape.com)
Function2
- Interestingly, although alcohols and amines can be Brønsted-Lowry acids, they can also function as Lewis bases due to the lone pairs of electrons on their oxygen and nitrogen atoms. (alchetron.com)
- This study aims to understand the function and mechanism of Drosophila Glycine N-acyltransferase (GLYAT) in cell invasion. (sdbonline.org)
Membrane1
- Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed [1][2]. (medchemexpress.com)
Cell1
- The studies reported in this paper describe the transport characteristics of certain neutral amino acids in monolayer cultures of the baby hamster kidney cell line BHK21-Cl3.Lalanine, which has been previously shown to be transported via the three major neutral amino acid transport systems in Ehrlich ascites carcinoma cells (Christensen, '69) was consequently examined in most detail. (docksci.com)
Found1
- Consumption of tea has been linked to a sense of relaxation commonly associated with the content of the non-proteinogenic amino acid theanine, which is found within the tea leaves. (mdpi.com)
Reactions2
- unless otherwise specified, acid-base reactions are assumed to involve the transfer of a proton (H + ) from an acid to a base. (alchetron.com)
- Note that chemists often write H + ( aq ) and refer to the hydrogen ion when describing acid-base reactions but the free hydrogen nucleus, a proton, does not exist alone in water, it exists as the hydronium ion, H 3 O + . Thus, an Arrhenius acid can also be described as a substance that increases the concentration of hydronium ions when added to water. (alchetron.com)
Substance1
- An Arrhenius acid is a substance that, when added to water, increases the concentration of H + ions in the water. (alchetron.com)
Transport3
- This amino acid appears to be transported essentially via a relatively low affinity, high capacity, sodium ion dependent transport system. (docksci.com)
- This alanine transport system was shown to exhibit a broad substrate specificity and appeared to be capable of transporting most naturally occurring neutral a-amino acids. (docksci.com)
- Prior to amino acid transport assay cells were harvested during exponential growth, inoculated into 60 mm petri dishes (Gibco-Biocult) a t a density of 5.3 x lo3 cells/cm' and incubated as above for 48 hours. (docksci.com)
Content1
- LPS presence was determined by measuring the 3-deoxy-d-manno-2-octulosonic acid (Kdo) content by the thiobarbituric acid method modified to correct interference due to deoxysugars [22]. (screeninglibraries.com)
Production1
- The available energy is gradually depleted and the metabolism displaces from aerobic to anaerobic, less efficient in energy [adenosine triphosphate (ATP)] generation, favoring lactic acid production. (earthwormexpress.com)
Cells1
- Additionally, the invention provides methods of making the compositions, as well as methods of introducing the nucleic acids into cells using the compositions and treating disease conditions. (justia.com)
Active1
- One of the active ingredients often mentioned as a candidate for interactions with caffeine is the beta-amino acid, taurine. (researchgate.net)
Water1
- the carbonic acid, in turn, forms water and CO 2 . (medscape.com)
Addition1
- Thus, buffers work as a first-line of defense to blunt the changes in pH that would otherwise result from the constant daily addition of acids and bases to body fluids. (medscape.com)
Examples1
- As these examples show, acids (in the colloquial sense) can be solutions or pure substances, and can be derived from acids (in the strict sense) that are solids, liquids, or gases. (alchetron.com)
Studies1
- Inhibition studies using other amino acids or their analogues provided information about the specificity of this system. (docksci.com)