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  • activity
  • Mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). (uniprot.org)
  • glyceraldehyde 3-phospha
  • It should not be confused with the similarly named glycerate 3-phosphate or glyceraldehyde 3-phosphate. (wikipedia.org)
  • This pathway involves condensation of a thiamine-activated acetyl group arising from the decarboxylation of pyruvate and glyceraldehyde-3-phosphate followed by a transposition step. (wikipedia.org)
  • Since both pyruvate and glyceraldehyde-3-phosphate (also glycerol) are part of the glycolytic pathway, varying levels of incorporations are expected. (wikipedia.org)
  • Thus, the terpenoid building blocks, dimethylallyl diphosphate and isopentenyl diphosphate, synthesized by the non-mevalonate pathway utilizing pyruvate and glyceraldehyde-3-phosphate, condense to form the diterpenoid precursor geranylgeranyl diphosphate that cyclizes to intermediate 3 which is related to (or derived from) ent-kaurene. (wikipedia.org)
  • molecule
  • Since there are two phosphates in the molecule, each of them can catch one proton. (wikipedia.org)
  • In prokaryotes such as bacteria, diphosphatidylglycerol synthase catalyses a transfer of the phosphatidyl moiety of one phosphatidylglycerol to the free 3'-hydroxyl group of another, with the elimination of one molecule of glycerol, via the action of an enzyme related to phospholipase D. The enzyme can operate in reverse under some physiological conditions to remove cardiolipin. (wikipedia.org)
  • Often, the terminal phosphate is split off during hydrolysis and transferred to another molecule. (wikipedia.org)
  • In the case of NADH, the molecule transfers a hydrogen, whereas acetyl CoA transfers an acetyl group, and ATP transfers a phosphate. (wikipedia.org)
  • Pathways
  • NAD(P)H + H+ → + NAD(P)+ It is also synthesized by phosphorylating glycerol generated upon hydrolyzing fats with glycerol kinase, and can feed into glycolysis or glyconeogenesis pathways. (wikipedia.org)
  • biosynthesis
  • View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate , the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism . (uniprot.org)
  • This family contains acyltransferases involved in phospholipid biosynthesis and proteins of unknown function. (wikipedia.org)
  • Synonyms
  • Other synonyms for this class of compounds are 2-acylglycero-3-phosphocholine, 1-lyso-2-acyl-sn-glycero-3-phosphocholine, β-lysophosphatidylcholine, 2-acylglycerophosphocholine, L-1-lysolecithin and 1-lecithin. (wikipedia.org)
  • metabolism
  • 2-acyl-sn-glycero-3-phosphocholines are a class of phospholipids that are intermediates in the metabolism of lipids. (wikipedia.org)
  • consists
  • Its structure consists of a 3-amino-2,4-dihydroxybenzoic acid polar part linked through an amide bond to a lipophilic pentacyclic ketolide. (wikipedia.org)
  • step
  • The following step is conversion of CDP-DAG to phosphatidylglycerol phosphate (PGP) by the enzyme PGP synthase, followed by dephosphorylation by PTPMT1 to form PG. (wikipedia.org)
  • group
  • The hydroxyl groups (-OH and -O−) on phosphate would form a stable intramolecular hydrogen bond with the centered glycerol's hydroxyl group, thus forming a bicyclic resonance structure. (wikipedia.org)
  • glycolysis
  • The sulfoglycolytic Embden-Meyerhof-Parnas (sulfo-EMP) pathway involves the degradation of sulfoquinovose to 2,3-dihydroxypropanesulfonate (DHPS), and shares similarity with the Embden-Meyerhof-Parnas glycolysis pathway. (wikipedia.org)
  • Alkyl
  • Biosynthesis of plasmalogens (PLs) begins with association of peroxisomal matrix enzymes GNPAT (glycerone phosphate acyl transferase) and AGPS (alkyl-glycerone phosphate synthase) on the luminal side of the peroxisomal membrane. (wikipedia.org)
  • Plasmenylcholine is formed from 1-O-alkyl-2-acyl-sn-glycerol by choline phosphotransferase. (wikipedia.org)
  • A new de novo pathway for the formation of 1-alkyl-2-acetyl-sn-glycerols, precursors of platelet activating factor. (wikipedia.org)
  • triglycerides
  • In the intestine, triglycerides are split into glycerol and fatty acids (this process is called lipolysis) with the help of lipases and bile secretions, which can then move into blood vessels. (hmdb.ca)
  • As the brain cannot utilize fatty acids as an energy source, the glycerol component of triglycerides can be converted into glucose for brain fuel when it is broken down. (hmdb.ca)
  • Industrial production is primarily achieved by a glycerolysis reaction between triglycerides and glycerol. (wikipedia.org)
  • synthase
  • Dependency of sugar transport and phosphorylation by the phosphoenolpyruvate-dependent phosphotransferase system on membranous phosphatidyl glycerol in Escherichia coli: studies with a pgsA mutant lacking phosphatidyl glycerophosphate synthase. (stepdb.eu)
  • phosphotransferase
  • As there is no plasmenylcholine desaturase choline plasmalogens can be formed only after hydrolysis of ethanolamine PLs to 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol that can be modified by choline phosphotransferase and CDP choline. (wikipedia.org)
  • glucose
  • Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa. (stepdb.eu)
  • Thus
  • The hydroxyl groups (-OH and -O−) on phosphate would form a stable intramolecular hydrogen bond with the centered glycerol's hydroxyl group, thus forming a bicyclic resonance structure. (wikipedia.org)
  • whereas
  • More recently, an experimental approach involving high-density transposon mutagenesis of the H. influenzae genome led to a much higher estimate of ≈670 putative essential genes ( 3 ), whereas transposon mutagenesis of two mycoplasma species led to an estimate of 265-360 essential genes ( 4 ). (pnas.org)
  • action
  • Sulfoquinovose is obtained from SQ glycosides by the action of sulfoquinovosidases, which are glycoside hydrolases that can hydrolyse the glycosidic linkage in SQDG, or its deacylated form, sulfoquinovosyl glycerol. (wikipedia.org)