Predicted to be involved in glycerol catabolic process and glycerol-3-phosphate metabolic process. (nih.gov)
Subunit1
Since glycerol is a main subunit in lipid metabolism, its abundance can easily lead to an increase in triglyceride accumulation at a cellular level. (wikipedia.org)
Glycerone phosphate2
Glycerol-3-phosphate dehydrogenase (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate (a.k.a. glycerone phosphate, outdated) to sn-glycerol 3-phosphate. (wikipedia.org)
The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. (thermofisher.com)
Quinone1
Once the glycerol-3-phosphate has moved through the outer mitochondrial membrane it can then be oxidised by a separate isoform of glycerol-3-phosphate dehydrogenase that uses quinone as an oxidant and FAD as a co-factor. (wikipedia.org)
Metabolic1
Glycerol 3-phosphate is a chemical intermediate in the glycolysis metabolic pathway. (hmdb.ca)
Protein2
Glycerol-3-phosphate dehydrogenase 2 is a novel factor H-, factor H-like protein 1-, and plasminogen-binding surface protein of Candida albicans. (leibniz-hki.de)
One 52-kDa protein was eluted and identified by mass spectrometry as glycerol-3-phosphate dehydrogenase 2 (Gpd2). (leibniz-hki.de)
DHAP3
The phosphate group of DHAP is half-encircled by the side-chain of Arg269, and interacts with Arg269 and Gly268 directly by hydrogen bonds (not shown). (wikipedia.org)
Glycerol 3-phospate may then be converted by dehydrogenation to dihydroxyacetone phosphate (DHAP) by the enzyme glycerol-3-phosphate dehydrogenase. (hmdb.ca)
One way to shuttle this reducing equivalent across the membrane is through the Glycerol-3-phosphate shuttle, which employs the two forms of GPDH: Cytosolic GPDH, or GPD1, is localized to the outer membrane of the mitochondria facing the cytosol, and catalyzes the reduction of dihydroxyacetone phosphate into glycerol-3-phosphate. (wikipedia.org)
In conjunction, Mitochondrial GPDH, or GPD2, is embedded on the outer surface of the inner mitochondrial membrane, overlooking the cytosol, and catalyzes the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate. (wikipedia.org)
Mitochondrial glycerol-3-phosphate dehydrogenase (GPD2), catalyzes the irreversible oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate and concomitantly transfers two electrons from FAD to the electron transport chain. (wikipedia.org)
The reactions catalyzed by cytosolic (soluble) and mitochondrial GPDH are as follows: There are two forms of GPDH: The following human genes encode proteins with GPDH enzymatic activity: Cytosolic Glycerol-3-phosphate dehydrogenase (GPD1), is an NAD+-dependent enzyme that reduces dihydroxyacetone phosphate to glycerol-3-phosphate. (wikipedia.org)
The cytosolic together with the mitochondrial glycerol-3-phosphate dehydrogenase work in concert. (wikipedia.org)
Cell damage was assessed using MTT assays, and the lactate dehydrogenase (LDH) release rate and flow cytometry were used to detect the accumulation of reactive oxygen species (ROS) and mitochondrial membrane potential respectively. (sdbonline.org)
GPD24
NaCl), GPD1 activity is enhanced over GPD2, since an increase in the salinity of the medium leads to an accumulation of glycerol in response. (wikipedia.org)
Enhanced GPDH activity, particularly GPD2, leads to an increase in glycerol production. (wikipedia.org)
Orthologous to human GPD2 (glycerol-3-phosphate dehydrogenase 2). (nih.gov)
The 3 human complement regulators, when attached to candida Gpd2, became functionally active, and the attached host proteins assist in inactivation of the complement cascade or cleave fibrinogen in the extracellular matrix component fibrinogen. (leibniz-hki.de)
Glyceraldehyde2
However, glycerol-3-phosphate dehydrogenase is not the same as glyceraldehyde 3-phosphate dehydrogenase (GAPDH), whose substrate is an aldehyde not an alcohol. (wikipedia.org)
Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Glycerol-3-Phosphate Dehydrogenase 1 (GPD1) were tested 20 times on one plate, respectively. (biomatik.com)
Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Glycerol-3-Phosphate Dehydrogenase 1 (GPD1) were tested on 3 different plates, 8 replicates in each plate. (biomatik.com)
This assay has high sensitivity and excellent specificity for detection of Glycerol-3-Phosphate Dehydrogenase 1 (GPD1). (biomatik.com)
No significant cross-reactivity or interference between Glycerol-3-Phosphate Dehydrogenase 1 (GPD1) and analogues was observed. (biomatik.com)
Shuttle1
The glycerol 3-phosphate shuttle is used to rapidly regenerate NAD+ in the brain and skeletal muscle cells of mammals (wikipedia). (hmdb.ca)
Enzyme1
Glycerol 3-phosphate is produced from glycerol, the triose sugar backbone of triglycerides and glycerophospholipids, by the enzyme glycerol kinase. (hmdb.ca)
S. uvarum is a cryotolerant yeast that produces more glycerol, less acetic acid and exhibits a better aroma profile. (frontiersin.org)
Increasing seed oil content in oil-seed rape (Brassica napus L.) by over-expression of a yeast glycerol-3-phosphate dehydrogenase under the control of a seed-specific promoter. (mpg.de)
Synthesis1
Increased levels of glycerol-3-phosphate lead to a stimulation of flux into triacylglycerol synthesis after supplying glycerol to developing seeds of Brassica napus L. in planta. (mpg.de)
Variants1
Castanheira E.B., Contel E.P.B. (1995) Isoenzymes related to flight activity in Tetragonisca angustula (Hymenoptera:Apidae: Meliponinae): Evidence of ponstranscional modification of the hexokinase and detection of new Glycerol-3-phosphate dehydrogenase variants, Biochem. (apidologie.org)
Assays1
Sensitive and high throughput metabolite assays for inorganic pyrophosphate, ADPGlc, nucleotide phosphates, and glycolytic intermediates based on a novel enzymic cycling system. (mpg.de)
Primary1
Therefore, the transcriptomic profile at different time points (days 3, 8, 15 and 21) along primary culture development of rainbow trout preadipocytes has been investigated using an Agilent trout oligo microarray. (biomedcentral.com)
Genes1
Proliferation cluster comprised 1028 genes up-regulated from days 3 to 8 of culture meanwhile the differentiation cluster was characterized by 2140 induced genes from days 15 to 21. (biomedcentral.com)
Lineage1
It was shown that Y. pestis recently diverged from Yersinia pseudotuberculosis , an enteropathogen, and likely comprises a clonal lineage ( 1 , 3 , 37 , 40 ). (asm.org)
Metabolite2
Objective Indole‐3‐carbinol (I3C), a naturally occurring compound found in cruciferous vegetables, and its metabolite 3,3′‐diindolylmethane (DIM) reduce body mass and serum glucose levels in high‐fat‐diet‐induced obese mice. (researchgate.net)
DIM, a major metabolite of indole-3-carbinol, which is naturally produced in broccoli and cabbage, enhances glucose uptake through the improvement of insulin sensitivity in 3T3-L1 cells [13] . (researchgate.net)
Complex1
Predicted to be part of glycerol-3-phosphate dehydrogenase complex. (nih.gov)
Process1
This time period includes the transit time for us to receive your return from the shipper (5 to 10 business days), the time it takes us to process your return once we receive it (3 to 5 business days), and the time it takes your bank to process our refund request (5 to 10 business days). (biomatik.com)
High1
In the present study, we obtained by rare mating (non-GMO strategy), and a subsequent sporulation, an interspecific S. cerevisiae × S. uvarum spore-derivative hybrid that improves or maintains a combination of parental traits of interest for the wine industry, such as good fermentation performance, increased ethanol tolerance, and high glycerol and aroma productions. (frontiersin.org)
Acid1
3,3 -diindolylmethane (DIM) is a natural compound produced from the acid-catalyzed self-condensation of indole-3-carbinol, which is abundant in cruciferous vegetables, such as broccoli and cabbage [11,12]. (researchgate.net)
Strains1
Y. pestis strains have historically been classified according to their ability to utilize glycerol and reduce nitrate and have been grouped into three main subtypes or biovars: antiqua, medievalis, and orientalis. (asm.org)
Include1
In conclusion, the present study suggests that management of southern Appalachian brook trout should include: (1) genetically cognizant planning of stocking events, (2) management of populations on a stream-by-stream basis, (3) prioritized conservation of pure southern brook trout populations, and (4) use of southern Appalachian hatchery stocks in restoration efforts. (intechopen.com)
Reduce1
biovars on the basis of their abilities to ferment glycerol and to reduce nitrate. (cdc.gov)