• The lysine-sensitive isoenzyme of aspartate kinase from spinach leaves has a subunit composition of 4 large and 4 small subunits [ PMID: 9584993 ]. (ebi.ac.uk)
  • The metabolic regulation of expression of an Arabidopsis thaliana aspartate kinase/homoserine dehydrogenase (AK/HSD) gene, which encodes two linked key enzymes in the biosynthetic pathway of aspartate family amino acids has been studied [ PMID: 9501134 ]. (ebi.ac.uk)
  • A study published in the Journal Neurochemical Research determined that since excessive accumulation of extracellular glutamate is linked with excitotoxicity, data implies that neonatal exposure to thimerosal-containing vaccines might induce excitotoxic brain injuries, leading to neurodevelopmental disorders. (wordpress.com)
  • Dihydrokainate (510 microMs) weakly inhibited the glutamate‐evoked current without generating a current itself. (deepdyve.com)
  • To date, however, only a few glutamate site antagonists have been found to display subtype selectivity, and these compounds are only weakly selective. (aspetjournals.org)
  • Purkinje cell loss in the Inpp4a (zeige INPP4A Antikörper )(wbl) mutant is due to glutamate (zeige GRIN1 Antikörper ) excitotoxicity initiated by the climbing fiber, and that Eaat4 may exert a protective effect. (antikoerper-online.de)
  • In conclusion, glutamate and aspartate enriched blood cardioplegia may be an alternative method for myocardial protection in patients with left ventricular dysfunction, in reoperations and in cardiac repairs necessitating longer aortic cross-clamp times. (dergisi.org)
  • This entry contains proteins with various specificities and includes the aspartate, glutamate and uridylate kinase families. (ebi.ac.uk)
  • 20 microMs), and kynurenate (1mM) had no effect on the glutamate‐evoked current. (deepdyve.com)
  • The effect of aspartate and glutamate enriched blood cardioplegia on myocardial nitric oxide production and left ventricular function was assessed on twenty patients undergoing elective coronary artery bypass grafing. (dergisi.org)
  • 3. The glutamate‐evoked current was activated by external cations with relative efficacies: Na+ much greater than Li+ greater than K+ greater than Cs+, choline. (deepdyve.com)
  • The K(m) values for aspartate were clearly different for the external and the internal sides of the membrane, 216 +/- 23-mu-M and 2.4 +/- 0.5 mM, respectively. (uni-bielefeld.de)
  • In this case the K(m) values for external and internal aspartate were determined to be 123 +/- 11-mu-M and 2.8 +/- 0.6 mM, respectively. (uni-bielefeld.de)