Glutamate and arginine. Medical search. Frequent questions

Aspartate, Glutamate: negative and acidic. (flashcardmachine.com)
This archaeal protein has been well conserved throughout evolution, and we know from previous work that it is a good model for the human transport protein, even though it transports aspartate and not glutamate,' explains Guskov. (rug.nl)

The unprotonated versions of the amino acids listed above can catalyze general base catalysis:, Glutamate, Histidine, Tyrosine, Cysteine At different times in an enzyme cycle, a single amino acid residue can engage in both general acid and general base catalysis. (assignmentexpert.com)

Nrd1 contains an RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), a short arginine-, serine-, and glutamate-rich segment similar to the regions rich in RE and RS dipeptides (RE/RS domains) in many metazoan splicing factors, and a proline- and glutamine-rich C-terminal domain (P+Q domain) similar to domains found in several yeast hnRNPs. (nih.gov)
It also contains one RRM motif and a region rich in arginine-serine dipeptides (RS domain). (nih.gov)

However, the effects of the ADRB2 glutamine (Gln) 27 glutamic acid (glutamate) (Glu) and ADRB3 tryptophan (Trp) 64 arginine (Arg) polymorphisms on weight loss remain controversial. (upm.es)

Arginine glutamate (also called glutargin) is a mixture of two amino acids, 50% arginine and 50% glutamic acid, used in liver therapy. (wikipedia.org)

Then, combined with the heatmap, KEGG and IPA, we found that arginine metabolism was differentially altered during different periods of OGD treatment. (biomedcentral.com)
Arginine metabolism pathway-related proteins were significantly altered by OGD treatment, which suggests that they may have a potential role in ischemic injury. (biomedcentral.com)
Analysis of glucose metabolism: insulin tolerance test, glucose tolerance test, glucose or arginine stimulated insulin secretion tests, glucagon, pyruvate, glutamate challenge tests, [14C]-2-deoxy-glucose uptake into mouse tissues, isolation of mouse islets. (nih.gov)

In addition, the results demonstrated that deletion of the clpB gene affected glucose consumption and L -arginine, L -glutamate, and lactate production during fermentation. (frontiersin.org)

The cause lies in a mutation that changes a single amino acid in a protein that transports the neurotransmitter glutamate across the membrane of neural cells. (rug.nl)
In human neural cells, this would lead to a reduced transport of the neurotransmitter glutamate, and increased anion imbalance. (rug.nl)

EA6 is linked to the mutation of a highly conserved proline into an arginine in the glutamate transporter EAAT1. (researchgate.net)
Illustration of the glutamate transporter (pink) in neural cells (blue), with glutamate and anions in yellow and orange. (rug.nl)

Acute decompensation: Because nitric oxide (NO) deficiency can play a major role in the pathogenesis of MELAS syndrome complications, supplementation of NO precursors, arginine and citrulline, can result in increased NO availability and so may have therapeutic effects on NO deficiency-related manifestations of MELAS syndrome. (medscape.com)
Patients with known MELAS who present with any symptoms suggestive of a metabolic stroke should receive a loading dose of intravenous arginine hydrochloride to reduce brain damage due to impaired vasodilation in intracerebral arteries caused by nitric oxide depletion. (medscape.com)
Short-term citrulline supplementation increases nitric oxide production to more than arginine because of the significant increase in de novo arginine synthesis associated with citrulline supplementation. (medscape.com)

At the moment, I am reluctant to accept the data unless I see the actual characterization of (IU)n. (8) I am also enclosing oligo glutamate synthesis using Polu AAG. (nih.gov)

The protein is inserted in the cell membrane, and the mutation changes a proline amino acid in one of the helical transmembrane domains into an arginine. (rug.nl)
What we noticed is that a salt bridge is formed between the arginine amino acid and the lipids of the membrane. (rug.nl)

Cationic arginine-rich peptides (CARPs) are an emerging therapeutic option that exerts various neuroprotective effects and may target the transmission of protein aggregates. (researchgate.net)
This protein transports glutamate across the membrane of neural cells,' explains structural biologist Albert Guskov. (rug.nl)
Somehow, the arginine that replaced the proline did not alter the shape of the transport protein, but it did affect its function. (rug.nl)

17. Thermodynamic characterization of the DmsD binding site for the DmsA twin-arginine motif. (nih.gov)

Therefore, in addition to arginine, administration of citrulline has the potential for therapeutic use in MELAS. (medscape.com)

We provide a set of high-resolution structures of this enzyme in ligand-free and pre- and post-reaction states, which reveals a specialized mechanism of catalysis that includes a key active-site arginine that extends the canonical ADP-ribosyltransferase toolkit. (nature.com)

Although there is no clinical evidence on how long to continue the maintenance dose of arginine, most mitochondrial specialists recommend continuing treatment for at least 3 days. (medscape.com)

15. The structure and IR signatures of the arginine-glutamate salt bridge. (nih.gov)