• The scientist's investigation covers issues in Glutamate receptor, Biochemistry, Endocrinology, Internal medicine and Choline acetyltransferase. (research.com)
  • His work in Choline acetyltransferase covers topics such as Anatomy which are related to areas like Acetylcholinesterase. (research.com)
  • A rapid radiochemical method for the determination of choline acetyltransferase. (research.com)
  • His scientific interests lie mostly in Biochemistry, Glutamate receptor, Internal medicine, Endocrinology and Choline acetyltransferase. (research.com)
  • His Choline acetyltransferase research is multidisciplinary, relying on both Glutamate decarboxylase, Acetylcholinesterase, Choline, Aromatic L-amino acid decarboxylase and Nucleus. (research.com)
  • His research in Cerebellar cortex tackles topics such as Choline which are related to areas like Choline acetyltransferase. (research.com)
  • Excitotoxicity was produced by intravitreal injection of NMDA (20 nmol in 5 /xl), which caused a decrease of cells in the ganglion cell layer (GCL) and retinal choline acetyltransferase activity (ChAT). (nebraska.edu)
  • Acetylcholine (ACh) is made in the brain by the enzyme choline acetyltransferase using two chemical compounds - choline and acetyl-CoA. (poweronpoweroff.com)
  • The HBP culminates in the production of an amino sugar uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) that, along with other charged nucleotide sugars, serves as the basis for biosynthesis of glycoproteins and other glycoconjugates. (biomedcentral.com)
  • Amino acid metabolism.biosynthesis.glutamate. (ntu.edu.sg)
  • For the typical bacterium that can make all 20 amino acids, there are 1-2 gaps in amino acid biosynthesis pathways. (lbl.gov)
  • For more information, see the paper from 2019 on GapMind for amino acid biosynthesis, the paper from 2022 on GapMind for carbon sources, or view the source code , or see changes to Amino acid biosynthesis since the publication. (lbl.gov)
  • His Glutamic acid study combines topics in areas such as Free nerve ending, Calcium metabolism, Mammalian brain, Receptor and Aspartate binding. (research.com)
  • The various areas that Frode Fonnum examines in his Glutamate receptor study include Amino acid, Glutamine, Neurotransmitter, Neuroscience and Metabolism. (research.com)
  • The depletion of DOM over time was strongly correlated with increases in expression of many genes associated with heterotrophy (e.g., amino acid, fatty acid, and carbohydrate metabolism) belonging to a Hydrogenophaga strain that accounted for a relatively large percentage (~8%) of the metatranscriptome. (frontiersin.org)
  • Two thirds of differentially expressed proteins were identified in the pathways of glycolysis, citric acid cycle, amino acid, sugar and starch metabolism. (biomedcentral.com)
  • GNA1/GNPNAT1 (glucosamine-6-phosphate N-acetyltransferase) then converts glucosamine-6P (which can also be made by glucosamine entering the cell) into GlcNAc-6P (N-acetylglucosamine-6-Phosphate), also utilizing acetyl-CoA that is made from fatty acid metabolism. (biomedcentral.com)
  • Gut microbes, including Bacteroides , Clostridium , and Lentisphaeria , make a contribution to the energy metabolism and synthesis of amino acid, which are essential to the normal growth of yaks. (animbiosci.org)
  • Glucose is the major substrate for ATP synthesis through glycolysis and oxidative phosphorylation (OXPHOS), whereas intermediary metabolism through the tricarboxylic acid (TCA) cycle utilizes non-glucose-derived monocarboxylates, amino acids, and alpha ketoacids to support mitochondrial ATP and GTP synthesis. (molvis.org)
  • Confocal studies showed differential cellular and compartmental distribution of isozymes involved in glucose, glutamate, glutamine, lactate, and creatine metabolism. (molvis.org)
  • Acetylglutamate synthetase may refer to: Amino-acid N-acetyltransferase Glutamate N-acetyltransferase This disambiguation page lists articles associated with the title Acetylglutamate synthetase. (wikipedia.org)
  • Evaluate the protection of eliprodil, an NMDA-receptor polyamine-site antagonist, against excitatory amino acid- or ischemia-induced insults on retinal cells and retina in vivo. (nebraska.edu)
  • Eliprodil is protective against cytotoxic insults due to ischemia or excitatory amino acids in retinal tissues and cells. (nebraska.edu)
  • The major neurotransmitters in your brain include glutamate and GABA, the main excitatory and inhibitory neurotransmitters respectively, as well as neuromodulators including chemicals such as dopamine, serotonin, norepinephrine and acetylcholine. (poweronpoweroff.com)
  • These PTMs act like little switches on a microchip, and are attached and removed by enzymes like kinases, phosphatases, acetyltransferases, deacetylases and ubiquitin ligases that are in turn regulated by external stimuli including insulin signaling, glutamate, GABA, and neuropeptide receptors. (unc.edu)
  • Unlike glutamate and GABA, whose cells are located throughout the brain, dopamine cell bodies are only found in small collections of nuclei within your "midbrain" - such as the ventral tegmental area and substantia nigra. (poweronpoweroff.com)
  • In the next step, the enzyme glucosamine-phosphate N-acetyltransferase (GNPNAT) catalyzes Ac-CoA and glucosamine-6-phosphate to generate N-acetylglucosamine-6-phosphate (GlcNAc-6P) and CoA. (biomedcentral.com)
  • Gene functional classification showed that most of enzyme-coding genes were related to cellulose digestion and amino acids metabolic pathways. (animbiosci.org)
  • Dopamine is synthesized from the precursor chemical L-Dopa by the enzyme aromatic L-amino acid decarboxylase (also called DOPA decarboxylase). (poweronpoweroff.com)
  • L-Dopa itself is generated from the amino acid L-Tyrosine (by the enzyme tyrosine hydroxylase) a process which requires various other supporting chemicals (called cofactors) including tetrahydrobiopterin (which is also required in the synthesis of several other neurotransmitters) and iron. (poweronpoweroff.com)
  • Mucopolysaccharidoses (MPSs) are a group of lysosomal storage diseases, each of which is produced by an inherited deficiency of an enzyme involved in the degradation of acid mucopolysaccharides, now called glycosaminoglycans (GAGs). (medscape.com)
  • A combination of methods, including the isobaric tags for relative and absolute quantification (iTRAQ), quantitative real-time polymerase chain reaction, gas chromatography, and high-performance liquid chromatography, was used to identify proteins, measure gene expression levels, volatiles, sugars, organic acids and carotenoids. (biomedcentral.com)
  • The biosynthetic gene clusters of these linaridins lack obvious candidate genes for the dehydratase and epimerase required to introduce dehydrobutyrine and D-amino acid residues, respectively. (hokudai.ac.jp)
  • The murI gene of Escherichia coli is an essential gene that encodes a glutamate racemase activity. (nih.gov)
  • ʟ-Ornithine is an important amino acid with broad applications in pharmaceutical and food industries. (biomedcentral.com)
  • Comment: In pathway II (acetyl cycle), instead of an acetylornithine deacetylase, the acetyltransferase argJ converts N-acetylornithine to ornithine. (lbl.gov)
  • The hexosamine biosynthetic pathway utilizes up to 2-5% of glucose that enters a non-cancer cell and along with glutamine, acetyl-coenzyme A (Ac-CoA) and uridine-5′-triphosphate (UTP) are used to produce the amino sugar UDP-GlcNAc [ 5 ]. (biomedcentral.com)
  • Glutamine fructose-6-phosphate amidotransferase (GFAT) converts F6P and glutamine to glucosamine-6-phosphate and glutamate in the rate-limiting step of HBP [ 6 ]. (biomedcentral.com)
  • Glutamate-cysteine ligase family 2(GCS2) [Interproscan]. (ntu.edu.sg)
  • Interestingly, mitochondrial translocation of APP was incomplete because of an internal acidic domain present between 220 and 290 amino acids. (jneurosci.org)
  • protein ARG5,6, mitochondrial;Amino acid kinase. (ntu.edu.sg)
  • Grisemycin, salinipeptin, and cypemycin belong to the linaridin class of ribosomally synthesized and posttranslationally modified peptides that contain multiple dehydrobutyrine and D-amino acid residues. (hokudai.ac.jp)
  • Furthermore, we demonstrated that GrmH/GrmL complex accepted salinipeptin and cypemycin precursor peptides, which possess three additional amino acids. (hokudai.ac.jp)
  • Since the HBP utilizes major macromolecules such as nucleotides, amino acids, carbohydrates, and lipids to produce UDP-GlcNAc, cells may use it as a 'sensor' of energy availability that influences a large number of functional targets that contribute to cancer phenotypes (Fig. 2 ). (biomedcentral.com)
  • His Glutamate receptor research includes themes of Amino acid, Glutamic acid, Neurotransmitter, Biophysics and Dopamine. (research.com)
  • GAGs are long, linear polysaccharide molecules composed of repeating dimers, each of which contains a hexuronic acid (or galactose in the case of keratan sulfate) and an amino sugar. (medscape.com)
  • The major constituent of a senile plaque is β-amyloid (Αβ), which is a 40-43 amino acid peptide produced by the action of secretory pathway-associated proteases, namely β and γ secretases, at the C terminus of a type I membrane-spanning glycoprotein termed amyloid precursor protein (APP). (jneurosci.org)
  • Ruminants (foregut fermentors) benefit from microbial protein as well as the absorption of energy that is released by anaerobic microorganisms in the form of fermentation acids [ 2 ]. (animbiosci.org)
  • L-tyrosine can also be synthesized from another amino acid - L-Phenylalanine - which is obtained from your diet. (poweronpoweroff.com)
  • Frode Fonnum combines subjects such as Kainic acid and Neurotoxicity with his study of Endocrinology. (research.com)
  • Eliprodil dose-dependently suppressed NMDA (200 /iM)-activated currents in RGC, and prevented cell death induced by 100 /*M glutamate with an ECSO of 1 nM. (nebraska.edu)
  • His study in Reactive oxygen species is interdisciplinary in nature, drawing from both Phospholipase A2, Medicinal chemistry, Nitric oxide and Phospholipase C. His study with Glutamate receptor involves better knowledge in Receptor. (research.com)
  • Then this NO further combines with water vapor of atmosphere to form nitric acid. (biokaryon.com)
  • The nitric acid combines with various salts present in the soil to form nitrates and nitrates. (biokaryon.com)
  • His primary scientific interests are in Biochemistry, Reactive oxygen species, Glutamate receptor, Apoptosis and Cyclosporin a. (research.com)
  • For axenic growth under laboratory conditions, it specifically relies on the external supply of N -acetylmuramic acid (MurNAc), which is an essential constituent of the peptidoglycan (PGN) of bacterial cell walls. (karger.com)