• In a 61-year-old man with glucose-6-phosphate dehydrogenase (G6PD) deficiency and poorly controlled non-insulin-dependent diabetes mellitus, an episode of acute haemolysis occurred after the administration of glyburide (glibenclamide). (nih.gov)
  • Since autoimmune haemolysis was excluded on the basis of laboratory data, acute haemolysis was ascribed to G6PD deficiency. (nih.gov)
  • Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect and one of the most common genetic disorders worldwide, with an estimated 400 million people worldwide carrying a mutation in the G6PD gene that causes deficiency of the enzyme. (tau.ac.il)
  • Although drug-induced haemolysis is considered the most common adverse clinical consequence of G6PD deficiency, significant confusion exists regarding which drugs can cause haemolytic anaemia in patients with G6PD deficiency. (tau.ac.il)
  • In the current review we aimed, by thorough search of the medical literature, to collect evidence on which to base decisions either to prohibit or allow the use of various medications in patients with G6PD deficiency. (tau.ac.il)
  • A literature search was conducted during May 2009 for studies and case reports on medication use and G6PD deficiency using the following sources: MEDLINE (1966May 2009), PubMed (1950May 2009), the Cochrane database of systematic reviews (2009), and major pharmacology, internal medicine, haematology and paediatric textbooks. (tau.ac.il)
  • Others were asymptomatic but belonged to a family with a history of G6PD deficiency. (hal.science)
  • The molecular analysis was performed by a combination of PCR-RFLP and DNA sequencing to characterize the mutations causing G6PD deficiency. (hal.science)
  • G6PD Deficiency and Antimalarial Efficacy for Uncomplicated Malaria in Bangladesh: A Prospective Observational Study. (ox.ac.uk)
  • 10% activity), five participants (5/174) had mild G6PD deficiency (10-60% activity). (ox.ac.uk)
  • The prevalence of G6PD deficiency was low. (ox.ac.uk)
  • Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a genetic disorder that is most common in males. (medlineplus.gov)
  • G6PD deficiency mainly affects red blood cells , which carry oxygen from the lungs to tissues throughout the body. (medlineplus.gov)
  • If you have G6PD deficiency, you may not have symptoms. (medlineplus.gov)
  • Glucose-6-phosphate dehydrogenase deficiency is an erythrocyte enzyme disorder caused by mutations in the G6PD gene , which has an X-linked inheritance . (bvsalud.org)
  • Here we analyze the clinical and laboratory characteristics of 24 subjects with G6PD deficiency over 25 years. (bvsalud.org)
  • La deficiencia de glucosa-6-fosfato deshidrogenasa es la enzimopatía eritrocitaria causada por mutaciones en el gen G6PD , cuya herencia está ligada al cromosoma X . Se analizan las características clínicas y de laboratorio de 24 individuos con deficiencia de G6PD durante 25 años. (bvsalud.org)
  • Drug-induced acute hemolytic anemia led to the discovery of G6PD deficiency. (ashpublications.org)
  • 2.5 mg/kg once daily for 3 days), 95 G6PD-deficient hemizygous boys, 24 G6PD-deficient homozygous girls, and 200 girls heterozygous for G6PD deficiency received this agent. (ashpublications.org)
  • Therefore, contrary to current perception, in clinical terms the A− type of G6PD deficiency cannot be regarded as mild. (ashpublications.org)
  • Glucose 6-phosphate dehydrogenase (G6PD) deficiency is common in populations that have been exposed to malaria, either in the present or in the past. (ashpublications.org)
  • Estimation of risk of glucose 6-phosphate dehydrogenase deficient red cells to ozone and nitrogen dioxide : investigator's final report / by Marie A. Amoruso. (who.int)
  • The importance of glucose-6-phosphate dehydrogenase deficiency in the causation of severe neonatal jaundice in Israel was investigated. (openu.ac.il)
  • The overall results suggest that although a few such cases may occur in this country, glucose-6- phosphate dehydrogenase deficiency cannot be considered an important aetiological factor in the causation of severe haemolytic neonatal jaundice in Israel, in spite of the existence of population groups with a very high frequency of the enzyme deficiency. (openu.ac.il)
  • Some patients with glucose--phosphate dehydrogenase deficiency in red cells and are transported to the aptt in some patients, some improvement may occur with a propensity to cause harm to patients who received radiation therapy with antiviral agents. (elastizell.com)
  • Title : Glucose-6-Phosphate Dehydrogenase Deficiency In Project Head Start Children Personal Author(s) : Kelly, S.;Almy, R. (cdc.gov)
  • Phenotypic and genotypic characterization of glucose-6-phosphate dehydrogenase deficiency in Argentina. (bvsalud.org)
  • Communities with very high frequencies of enzyme deficiency and those in which it was very rare did not differ significantly in the frequency of severe neonatal jaundice not due to iso-immunization. (openu.ac.il)
  • However, in one investigated sample of Iraqi Jews the number of enzyme-deficient cases among the jaundiced infants was significantly higher than expected from the gene frequency, suggesting that some cases of haemolytic disease of newborn due to enzyme deficiency did occur in this group. (openu.ac.il)
  • A number of ventilator-free and shock-free days during the day.Thus diurnal enuresis is most often as needed saba, inhaled short-acting - agonist such as congenital deficiency of the portal blood flow is the preferred method of system calibration is to block cytokine-mediated inflam-mation. (elastizell.com)
  • Mannosidase Deficiency Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
  • It is available as a prescription only medicine and is commonly used for GTP-CH Deficiency, Neuroleptic Malignant Syndrome, Parkinson's Disease, Restless Legs Syndrome. (art-pasion.es)
  • Disorders in pyruvate metabolism appear to lead to deficiencies in neurotransmitter synthesis and, consequently, to nervous system disorders. (nih.gov)
  • Hemolysis and anemia persist after splenectomy, although some improvement may occur, particularly in patients with pyruvate kinase deficiency. (msdmanuals.com)
  • This graph shows the total number of publications written about "Mannosidase Deficiency Diseases" by people in this website by year, and whether "Mannosidase Deficiency Diseases" was a major or minor topic of these publications. (ouhsc.edu)
  • Below are the most recent publications written about "Mannosidase Deficiency Diseases" by people in Profiles. (ouhsc.edu)
  • Results of search for 'su:{Glucosephosphate dehydrogenase deficiency. (who.int)
  • Chrome deficiency is common in non-diabetic dependent diabetics, contributing to increased cholesterol and cholesterol. (alliedmortgage.ca)
  • Inherited abnormalities of fructose metabolism, which include three known autosomal recessive types: hepatic fructokinase deficiency (essential fructosuria), hereditary fructose intolerance, and hereditary fructose-1,6-diphosphatase deficiency. (sdsu.edu)
  • Overexpression of Dwarf promoted net photosynthetic rate ( P N ), whereas BR deficiency in d im led to a significant inhibition in P N as compared with WT. (biomedcentral.com)
  • A single patient with mutation (Asn126Asp) showed a 21% decrease in G6PD activity, two subjects showed G6PD deficiency without mutations, and one patient had a decreased level of G6PD mRNA and reduced enzyme levels. (nih.gov)
  • Estimation of risk of glucose 6-phosphate dehydrogenase deficient red cells to ozone and nitrogen dioxide : investigator's final report / by Marie A. Amoruso. (who.int)
  • 10. The relationship between the enzyme activity, lipid peroxidation and red blood cells deformability in hemizygous and heterozygous glucose-6-phosphate dehydrogenase deficient individuals. (nih.gov)
  • Glucosephosphate isomerase (GPI) deficiency in humans is an autosomal recessive disorder, which results in nonspherocytic hemolytic anemia of variable clinical expression. (nih.gov)
  • Glucose phosphate isomerase (GPI) deficiency is an inherited disorder that affects red blood cells, which carry oxygen to the body's tissues. (nih.gov)
  • Mohrenweiser and Neel identified thermolabile variants of lactate dehydrogenase B, can toothpaste affect blood sugar glucosephosphate isomerase, and glucose 6 phosphate dehydrogenase. (gsac.ge)
  • A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of GLUCOSE-6-PHOSPHATE DEHYDROGENASE activity in erythrocytes, leading to hemolytic anemia. (nih.gov)
  • A 4-year-old female with severe congenital hemolytic anemia had low red cell GPI activity of 15.5 IU/g Hb (50% of normal mean) indicating GPI deficiency. (nih.gov)
  • 11. Molecular Analysis of Glucose-6-Phosphate Dehydrogenase Gene Mutations in Bangladeshi Individuals. (nih.gov)
  • Hemolysis and anemia persist after splenectomy, although some improvement may occur, particularly in patients with pyruvate kinase deficiency. (msdmanuals.com)
  • We assessed the prevalence of three common hereditary blood disorders [‎sickle-cell and beta-thalassaemia traits and glucose 6-phosphate dehydrogenase deficiency]‎ among the Omani population. (who.int)
  • About 27% of Omani males had inherited glucose-6-phosphate dehydrogenase deficiency [‎compared with 11% of females]‎ while countrywide prevalence rates for the sickle-cell and beta-thalassaemia traits were estimated to be 5.8% and 2.2% respectively and showed no significant gender differences. (who.int)
  • Deficiencia enzimática que produce una enfermedad con muchas variantes, algunas de las cuales causa déficit de la actividad enzimática en los eritrocitos, que genera una anemia hemolítica. (bvsalud.org)
  • 19. [Clinical evaluation of a melting curve analysis-based PCR assay for glucose phosphate dehydrogenase gene mutation detection]. (nih.gov)
  • While the biochemical defect has been quantified, the genetic basis of the deficiency is unknown. (nih.gov)
  • Under nitrogen deficiency situation, Nannochloropsis spp. (biomedcentral.com)
  • Mechanisms of this process from the perspective of transcriptome and metabolome have been obtained previously, yet proteome analysis is still sparse which hinders the analysis of dynamic adaption to nitrogen deficiency. (biomedcentral.com)