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  • uptake
  • In this review, we consider the involvement of these cation channels and transporters in the regulation of glucose uptake in the small intestine. (mdpi.com)
  • To assess the effect of C. ramosum on expression of genes involved in lipid uptake, mRNA levels of the Cd36 gene and the genes coding for intestinal fatty acid binding protein (Fabp2), fatty acid transport protein 4 (Fatp4), and lipid storage protein perilipin 2 (Plin2) were determined in all groups. (nih.gov)
  • PDX1
  • Diseases associated with PDX1 include Mody, Type Iv and Pancreatic Agenesis 1 . (genecards.org)
  • WB analysis of HEK293 (1) and PDX1 (AA: 39-283)-hIgGFc transfected HEK293 (2) cell lysate using GTX60573 PDX1 antibody [5A (genetex.com)
  • obesity
  • There is a rising trend of overweight and obesity in individuals with type 1 diabetes (T1D). (touchendocrinology.com)
  • The prevalence of overweight and obesity among newly diagnosed T1D subjects was 21-22% in the 2-19 year age group in the Pediatric Diabetes Consortium and the SEARCH for Diabetes in Youth study. (touchendocrinology.com)
  • 1,2 This has been attributed to a general worldwide increase in prevalence of obesity and similar risk factors such as family history, ethnicity, and sedentary lifestyle may be contributory. (touchendocrinology.com)
  • Obesity is a major public health problem on the world and Mexico too, in addition the obesity develops chronic non-communicable diseases (NCD) such as type 2 diabetes mellitus (T2DM) and c. (bioportfolio.com)
  • Oral Glucose Tolerance is Associated with Neuroelectric Indices of Attention Among Adults with Overweight and Obesity. (bioportfolio.com)
  • Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis. (bioportfolio.com)
  • In addition to the established association between general obesity and breast cancer risk, central obesity and circulating fasting insulin and glucose have been linked to the development of this commo. (bioportfolio.com)
  • Obesity and abnormal glucose tolerance in the offspring of mothers with diabetes. (bioportfolio.com)
  • Type 2 diabetes and obesity during childhood, puberty, and adulthood have become more common. (bioportfolio.com)
  • 2 But despite this alarming obesity epidemic (technically it is a pandemic , because the entire world is suffering from this problem) there has never been more debate about what exactly is causing the issue. (thepaleodiet.com)
  • T2DM
  • Type 2 diabetes mellitus (T2DM) is a global crisis. (benthamscience.com)
  • Poor blood glucose control and its associated risk factors resulting in disabling complications will have a catastrophic impact on patients with T2DM, their families, society, the healthcare system and the economy. (benthamscience.com)
  • In particular, HF is a major comorbidity in patients with type 2 diabetes mellitus (T2DM), which is caused by diverse pathogenic factors such as the cardiotoxic tetrad of coronary artery disease, diabetic cardiomyopathy, or hypertension. (biomedcentral.com)
  • T2DM is a progressive disease which can lead to numerous macrovascular complications such as myocardial infarction, amputation, stroke, as well as microvascular complications such as nephropathy, retinopathy, and neuropathy (2). (sjsm.org)
  • Therefore, it is crucial that glucose levels in patients diagnosed with T2DM are adequately controlled. (sjsm.org)
  • humans
  • Increasing our understanding of the extrinsic, as well as intrinsic, mechanisms that control these processes should facilitate efforts to regenerate this important cell type in humans. (biologists.org)
  • kidneys
  • T 2 DM affects several major organs, including heart, blood vessels, nerves, eyes and kidneys leading to disabling or even life-threatening complications such as cardiac dysfunction, atherosclerosis, and nephropathy [ 7 ]. (ijbs.com)
  • treatment
  • These medicinal herbs have been traditionally used for the treatment of T 2 DM since 1550 BC. (ijbs.com)
  • Hypoglycemia-associated autonomic failure (HAAF) constitutes one of the main clinical obstacles to optimum treatment of type 1 diabetes. (nih.gov)
  • There are many pharmacological treatment options available for Type 2 diabetes once management with diet and exercise fails. (sjsm.org)
  • diabetic
  • These antioxidants have been proposed as potential anti-diabetic drugs by acting as biological targets involved in T 2 DM development. (ijbs.com)
  • Moreover, we highlighted the anti-diabetic effects of the flavonoids in the management of T 2 DM, through modulating glucose transporters, with particular emphasis on the investigations and recent findings. (ijbs.com)
  • plasma
  • The study will compare plasma and urine post-prandial metabolomics after fat and glucose oral load according to lifestyle factors. (bioportfolio.com)
  • expression
  • GOS also up-regulated the protein expression of glucagon-like peptide-2 (GLP-2) and EGF in the jejunum of the piglets. (biomedcentral.com)