• This study, part of the Tehran Lipid and Glucose Study, determined and compared the prevalence of overweight and its associated risk factors in 2 555, 1 329 and 1 158 Tehran children and adolescents in 2000, 2003 and 2006 respectively. (who.int)
  • Overall the prevalence of obesity in Tehran children and adolescents increased significantly from 2000 to 2006 while blood pressure and serum lipid concentrations decreased. (who.int)
  • The risk and added values of the atherosclerotic cardiovascular risk enhancers on prediction of cardiovascular events: Tehran lipid and glucose study. (physiciansweekly.com)
  • Based on data regarding nutrition transition in the Middle East and North Africa, this study aim to investigate the general structure and secular trend of dietary patterns reported from the Tehran Lipid and Glucose Study (TLGS) and adherence to these dietary patterns among Iranian population from 2006 till 2017. (biomedcentral.com)
  • Parental Transmission Plays the Major Role in High Aggregation of Type 2 Diabetes in Iranian Families: Tehran Lipid and Glucose Study. (bvsalud.org)
  • This study is the first to evaluate familial aggregation, heritability and inheritance mode of type 2 diabetes (T2D) in Tehran Lipid Glucose Study (TLGS) participants as a representative sample of the Iranian population . (bvsalud.org)
  • Motaghipour Y, Valaei F, Amiri P, Azizi F, Hajipour R. Study of the general mental health status in an area of Tehran: Tehran Lipid and Glucose Study (TLGS). (ac.ir)
  • She has collaborated in research projects including the Tehran lipid and glucose prospective cohort study and clinical trials. (who.int)
  • This comprehensive analysis of data from the ziprasidone clinical trial database demonstrates limited evidence of any clinically significant adverse effects of ziprasidone on weight and consistent evidence of a neutral effect on fasting plasma lipids and glucose. (psychiatrist.com)
  • The causes for the decreased blood pressure and serum lipid concentrations should be evaluated. (who.int)
  • At the end of the exposure, fasting blood glucose and serum insulin were evaluated before epididymal adipose tissue and liver were collected, flow cytometry, quantitative PCR and Western blot were performed at euthanasia. (deepdyve.com)
  • The aim of the present work was to evaluate serum glucose concentration and lipid profile in racing horses in Iraq. (vetmedmosul.com)
  • Serum glucose concentration and lipid profile in racing horses', Iraqi Journal of Veterinary Sciences , 26(1), pp. 1-3. (vetmedmosul.com)
  • Vels of MC4R Agonist Synonyms plasma glucose, glycosylated hemoglobin (HbA1c) and plasma lipids, the homeostasis model assessment-insulin secretion index (HOMA- ) and HOMA-insulin resistance index (HOMA-IR), at the same time as the incidence of hypoglycemia, adverse cardiovascular events and physique mass index (BMI). (dna-alkylating.com)
  • Also, Vitamin C impacts lipid and glucose homeostasis and suppresses visceral obesity and NAFLD by activating PPAR [25]. (atminhibitor.com)
  • Given the central role of the liver in peripheral glucose homeostasis, we exposed mice to filtered air or PM 2.5 for 16 weeks and examined its effect on hepatic metabolic pathways using stable isotope resolved metabolomics (SIRM) following a bolus of 13 C 6 -glucose. (elsevierpure.com)
  • Changes in weight, fasting lipids, and fasting glucose from baseline to study end (last observation carried forward [LOCF]) for adult subjects in Pfizer-sponsored oral monotherapy randomized placebo-controlled ziprasidone clinical trials were analyzed by using an analysis of covariance model. (psychiatrist.com)
  • During fasting and other catabolic states, GH predominantly stimulates the release and oxidation of FFA, which leads to decreased glucose and protein oxidation and preservation of LBM and glycogen stores. (scienceopen.com)
  • The fasting plasma glucose level within the insulin-glargine group was considerably lower than that observed within the standardcare group. (dna-alkylating.com)
  • Additionally, diabetes has been identified to become an independent danger aspect for cardiovascular disease, whereby an elevated fasting plasma glucose (FPG) level is regarded to be substantial (two,3). (dna-alkylating.com)
  • Android, gynoid, visceral, and subcutaneous abdominal fat masses (via dual energy X-ray absorptiometry ) and fasting glucose and lipid profiles were assessed at baseline and 6 months. (karger.com)
  • Although there is no cure, a diet that avoids fasting to maintain normal glucose level is the mainstay of life-long treatment. (medscape.com)
  • Glycosylated haemoglobin HbA1c (the diabetes test): This is the level of glucose (sugar) molecules bound to haemoglobin (the protein in red blood cells that carries oxygen in the blood to all tissues) in the blood. (theonlineclinic.co.uk)
  • Diabetes is characterised by raised levels of blood glucose (HbA1c), which affects the blood vessels causing heart attacks, stroke, and kidney, eye and nerve damage. (theonlineclinic.co.uk)
  • Most common is type 2 diabetes, which occurs when the pancreas does not produce sufficient insulin or becomes resistant to insulin, the hormone regulating blood glucose levels. (theonlineclinic.co.uk)
  • Background: People with type 1 diabetes generally view it easier to exercise when having continuous information of the glucose levels. (lu.se)
  • We evaluated whether patients with type 1 diabetes managed with multiple daily insulin injections (MDI) exercised more after initiating continuous glucose monitoring (CGM) and whether the improved glycemic control and well-being associated with CGM translates into improved blood lipids and markers of inflammation. (lu.se)
  • Conclusion: Although many patients experience it easier to perform physical activity when monitoring glucose levels with CGM, it does not influence the amount of physical activity in persons with type 1 diabetes. (lu.se)
  • 2007). Emerging evidence from both epidemiological and experimental studies indicates the adverse consequences of PM2.5 exposure on diabetes, including worsening of whole-body insulin sensitivity, glucose tolerance impairment, lipid accumulation, and glucose metabolism dysfunction (Hwang et al. (deepdyve.com)
  • High triglycerides -- a type of fat, or lipid, in the blood -- increase the risk of heart disease and perhaps type 2 diabetes. (sciencedaily.com)
  • The next phase will be to determine clinical success in patients with type 2 diabetes on the whole range of diabetic medications or perhaps with less severe lipid problems. (sciencedaily.com)
  • Et av stiftelsens viktigste formål er å støtte diabetesrelatert forskning som tar sikte på å gjøre livet enklere og bedre for mennesker som er rammet av diabetes i påvente av en kur - og ikke minst er vårt langsiktige mål å finne en endelig kur for diabetes. (diabeteswellness.no)
  • Diabetes Wellness Norge er en innsamllingsstiftelse godkjent av Innsamlingskontrollen. (diabeteswellness.no)
  • Vårt langsiktige mål er å finne en endelig kur for diabetes. (diabeteswellness.no)
  • We have shown that type 2 diabetic patients are characterized by insulin resistance in skeletal muscle and that exercise can counteract this defect and improve blood glucose levels, Type 2 diabetes shares many features of accelerated aging including poor glucose handling, insulin resistance and loss of muscle mass. (diabeteswellness.no)
  • This research project is designed to test whether low-intensity physical activity by breaking up sedentary behavior will improve glucose control in people with type 2 diabetes. (diabeteswellness.no)
  • Within the early stages of kind 2 diabetes (T2D), many residual -cells stay, hence, early insulin therapy can boost -cell function and boost the handle of plasma glucose levels. (dna-alkylating.com)
  • There is an emerging view that type 2 diabetes (hereafter diabetes) may reflect not so much as an isolated impairment of glucose regulation, rather the complex metabolic consequences of accumulating ectopic lipids or hepatic fat [ 1 - 4 ]. (biomedcentral.com)
  • Lai, MH, Cheng, HH & Huang, CL 2001, ' Relationship between dietary intakes and blood glucose and lipid concentrations in the usual time and the Chinese New Year period in patients with non-insulin-dependent diabetes mellitus ', Nutritional Sciences Journal , 卷 26, 編號 2, 頁 89-97. (tmu.edu.tw)
  • More than 90% of diabetes cases are type 2 diabetes characterized by persistent increase in glucose (hyperglycemia), lipid, and protein metabolic disorders that may induce insulin resistance. (nioh.ac.za)
  • Individuals who suffer from type 2 diabetes are partly characterized by down-regulation of glucose transport and mitochondrial lipid oxidizing genes. (nioh.ac.za)
  • Is the risk for severe illness associated with high glucose levels or specific diabetes medications? (cdc.gov)
  • From these results, we make the hypothesis that in CS rats, CCK increased pancreatic secretion, which may favor a quicker absorption of carbohydrates and consequently induces an enhanced inhibition of lipid oxidation in the liver, leading to a progressive accumulation of fat preferentially in visceral deposits. (frontiersin.org)
  • Lipid accumulation product (LAP) is an alternative continuous index of lipid accumulation, which is computed from waist circumference (WC, cm) and triglycerides (TGs, mmol/l): (WC-65) ×TG (men) and (WC-58) ×TG (women). (biomedcentral.com)
  • Lipid accumulation should be defined and measured specifically in those contexts where accumulation may represent a physiologic danger [ 6 , 7 ]. (biomedcentral.com)
  • These contexts might be described as lipid over accumulation [ 8 ]. (biomedcentral.com)
  • Kahn described a simple index for estimating lipid over accumulation among adults - designated the "lipid accumulation product" (LAP) - based on a combination of two measurements that are safe and inexpensive to obtain. (biomedcentral.com)
  • If LAP is better correlated than BMI with cardiovascular risk factors, this finding would support the notion that the over accumulation of lipid carries worse cardiovascular consequences than the less specific over accumulation of weight [ 9 ]. (biomedcentral.com)
  • conversely, VDR activation in hepatocytes could accelerate lipid accumulation [30]. (atminhibitor.com)
  • However, whether mitochondrial function and content are important in the prevention of lipid-induced muscular fat accumulation and IR has not been firmly established. (medscape.com)
  • An interesting model in this context is the model of lipid infusion, whereby elevation of circulating fatty acids rapidly leads to the accumulation of IMTGs in skeletal muscle and the development of IR within 3−24 h after the onset of lipid infusion. (medscape.com)
  • Liver, muscle, and intestine tissue samples were taken to measure mRNA expression of key genes involved in glucose, lipid, and protein metabolism. (frontiersin.org)
  • PFHpS exposure altered the expression of genes associated with steatosis, fatty acid metabolism, hepatotoxicity, lipid transport, and necrosis. (cdc.gov)
  • We previously reported that rats prone to obesity exhibit an exaggerated increase in glucose oxidation and an exaggerated decline in lipid oxidation under a low-fat high-carbohydrate (LF/HC) diet. (frontiersin.org)
  • Glucose and lipid oxidation were also assayed during the GTT. (frontiersin.org)
  • In this study, we accessed NRF-1 and its target gene expression crucial in glucose transport and lipid oxidation during exercise. (nioh.ac.za)
  • Anti-diabetic and dyslipidemia-correcting effects of bergamot polyphenols may be explained by their ability to activate AMP kinase (AMPK), which is a central regulator of glucose and fatty acids metabolism and inhibit cAMP phosphodiesterases (PDE), involved in regulation of lipolysis in adipocytes and liver. (bergamotaustralia.com.au)
  • ITT, GTT, and MTT showed that CS rats were neither insulin resistant nor glucose intolerant, but mRNA expression of cholecystokinin (CCK) in the duodenum was higher and that of CPT1, PPARα, and PGC1α in liver were lower than in CR rats. (frontiersin.org)
  • To our knowledge, this is one of the first studies to examine 13 C 6 -glucose utilization in the liver following PM 2.5 exposure, prior to the onset of insulin resistance (IR). (elsevierpure.com)
  • Volanesorsen, an experimental lipid-lowering medication, improved insulin sensitivity and glucose control by significantly decreasing patients' overall hemoglobin A1c -- the standard clinical measurement of blood glucose levels for diabetics -- in a new study. (sciencedaily.com)
  • For the first time, it has been shown that profoundly lowering triglycerides in diabetics improves their insulin sensitivity over time, which helps them maintain healthy glucose -- blood sugar -- levels. (sciencedaily.com)
  • If improved insulin sensitivity and improved glucose control are truly the result of lowering triglycerides, researchers suggest these other novel drugs should show the same effect. (sciencedaily.com)
  • We found that Reptin deletion completely rescued pathological phenotypes associated with IR, including glucose intolerance, hyperglycaemia, hyperlipidaemia and hepatic steatosis. (nih.gov)
  • 2017). The inhibition of hypothalamic inflammation by intracerebroventricular (ICV) administration of IKK2 inhibitor (IMD-0354) rectified PM2.5-induced glucose intolerance, IR, energy metabolism dysfunction, and attenuated peripheral inflammation in response to PM2.5 exposure (Song et al. (deepdyve.com)
  • ABSTRACT Studies have shown that cardiovascular risk factors, such as obesity, blood lipid levels, start early in childhood and some are on the rise in children. (who.int)
  • Method: The GOLD trial was a randomized cross-over trial over 16 months where patients used either CGM or capillary self-monitoring of blood glucose (SMBG) over six months, with a four-month wash-out period between the two treatment periods. (lu.se)
  • We compared grade of physical activity, blood lipids, apolipoproteins, and high-sensitivity C-reactive protein (hsCRP) levels during CGM and SMBG. (lu.se)
  • Blood lipids, apolipoprotein, and hsCRP levels were similar during CGM and SMBG. (lu.se)
  • This technique infuses insulin at fixed rates, and infuses glucose at a varying rate to keep blood glucose constant, in order to determine how well a patient responds to insulin. (sciencedaily.com)
  • Our objective is to identify a simple and time effective activity-based intervention that will improve metabolic control and improve daily blood glucose. (diabeteswellness.no)
  • During weeks 2 and 3, glucose tolerance tests (GTT), insulin tolerance tests (ITT), and meal tolerance tests (MTT) were performed to evaluate blood glucose, plasma, and insulin. (frontiersin.org)
  • The study investigated the relationship between normal dietary intake and blood glucose and lipid concentrations and intake over the Chinese New Year period in normal, mild hyperglycemia and severe hyperglycemia subjects. (tmu.edu.tw)
  • ECG Heart rate, Blood glucose, Blood lipid measuring. (aoke-elec.com)
  • Visits for obesity were 25% more likely to include assessments of height and weight and of blood pressure, and more than 50% more likely to include testing of blood glucose and lipids, compared with visits for other diagnoses. (cdc.gov)
  • TUESDAY, May 19, 2015 (HealthDay News) -- For patients with coronary artery disease (CAD) pretreated with lipid-lowering therapy, daily glucose fluctuation may affect coronary plaque vulnerability, according to a study published in the May issue of JACC: Cardiovascular Interventions . (healthday.com)
  • Therefore, the primary aim of our study was to test the hypothesis that a high mitochondrial oxidative capacity could prevent the development of lipid-induced IR. (medscape.com)
  • To this end, the current study examined the development of lipid-induced IR in endurance-trained athletes, who were selected based on a high maximal oxygen uptake in a graded exercise test and compared with untrained, but otherwise healthy, subjects. (medscape.com)
  • GH is a counterregulatory hormone that antagonizes the hepatic and peripheral effects of insulin on glucose metabolism via mechanisms involving the concomitant increase in FFA flux and uptake. (scienceopen.com)
  • Moreover, Vitamin D favors glucose uptake within the muscle by intensifying the intracellular expression on the insulin receptor substrate (IRS)-1 and enhancing the insulindependent glucose transporter 4 (GLUT-4) on fat tissues [11]. (atminhibitor.com)
  • Signaling data support the notion that high glucose uptake in trained subjects is maintained by shuttling glucose toward storage as glycogen. (medscape.com)
  • There was no effect on plasma lipids or uric acid, but there was a lower glucose and insulin peak concentration after consumption of the FVPD compared with the sugar-matched control. (cambridge.org)
  • The lipid bilayer of cell membranes is impermeable to large and polar molecules but permeable to water molecules and other small uncharged molecules like O 2 and CO 2 . (wikibooks.org)
  • The un-ionized form is usually lipid soluble (lipophilic) and diffuses readily across cell membranes. (msdmanuals.com)
  • The ionized form has low lipid solubility (but high water solubility-ie, hydrophilic) and high electrical resistance and thus cannot penetrate cell membranes easily. (msdmanuals.com)
  • Not only do we have a variety of very potent options emerging, we may be able to help improve glucose at the same time. (sciencedaily.com)
  • Lipid-based nanoparticle (LBNP) systems represent one of the most promising colloidal carriers for bioactive organic molecules. (mdpi.com)
  • Glycogen storage diseases (GSDs) are inherited disorders due to enzymatic defects that prevent breakdown of stored glycogen into glucose. (medscape.com)
  • Glycogen storage diseases ( GSD ) are a group of inherited autosomal recessive disorders caused by genetic mutations that lead to the inability to breakdown and metabolize glycogen into glucose. (medscape.com)
  • In untrained subjects, lipid infusion reduced oxidative and nonoxidative glucose disposal (NOGD), whereas trained subjects were completely protected against lipid-induced reduction in NOGD, supported by dephosphorylation of glycogen synthase. (medscape.com)
  • Nuclear respiratory factor, (NRF)-1, is a mitochondrial transcriptional factor shown to be involved in glucose transport and acts as potential therapeutic modality in the management of T2DM. (nioh.ac.za)
  • Masaru Kuroda, M.D., from the Kobe University Graduate School of Medicine in Japan, and colleagues examined the effect of daily glucose fluctuation on coronary plaque properties in patients with CAD pretreated with lipid-lowering therapy. (healthday.com)
  • Daily glucose fluctuation may have an effect on coronary plaque vulnerability in patients with CAD pretreated with lipid-lowering therapy,' the authors write. (healthday.com)
  • Further investigations should address the rationale for the early detection and control of glucose fluctuation in the era of universal statin use for CAD patients. (healthday.com)
  • We conclude that chronic exercise training attenuates lipid-induced IR and specifically attenuates the lipid-induced reduction in NOGD. (medscape.com)
  • In this context, slowing down the rate of glucose absorption by adding insoluble fibers to a high sucrose diet was shown to reduce fat deposition and alleviate the evolution of the symptoms of metabolic syndrome ( 14 ). (frontiersin.org)
  • Testing with the API-Coryne strip (bioMérieux, Marcy l'Etoile, France) showed that the strain was nitrate-reduction positive and produced acid from glucose, ribose, sucrose, and maltose. (cdc.gov)