Lipid MetabolismUptakePhysiologyHepatic glucose productionLiverGlycogenPhosphorylated to glucose 6-phosphaPlasma glucoseMetabolicRegulatesAdipose tissueEndocrinology and metabolismAnaerobicRegulation of energy metabolismFattyGlycolysisNonalcoholic steatohepatitisAerobicBoostDiabetesHomeostasisCell MetabolismHealthy glucoseInsulin sensitivityAmino acidsThermogenesisIntoleranceApoptosisMoleculeOxygenLevelsCellularTransportersFructoseFastingToleranceTranscriptionalSugarProteinsAppetiteIntakeHyperglycemiaBrainNADPHCarbohydratesClinicalConsumptionCarbohydrateVariabilityNutrientsProductionMiceConcentrationProteinBody's
Lipid Metabolism7
- Central IKK2 Inhibition Ameliorates Air Pollution-Mediated Hepatic Glucose and Lipid Metabolism. (deepdyve.com)
- We therefore investigated the effects of PM2.5 exposure on insulin resistance and the disorders of hepatic glucose and lipid metabolism via hypothalamic inflammation. (deepdyve.com)
- Therefore, our current finding indicates an important role of hypothalamic inflammation in PM2.5 exposure-mediated hepatic glucose and lipid metabolism disorder. (deepdyve.com)
- 2017). Whether central inhibition of IKK2 could reverse the dysfunction of glucose and lipid metabolism remains unknown. (deepdyve.com)
- Uniquely, this drug also activates PPAR gamma, which may provide potential additive or synergistic effects in regulating dysfunctional brain glucose energy and lipid metabolism in AD. (medscape.com)
- Biomarkers of all three AD diagnostic criteria (amyloid/tau/neurodegeneration) were improved, as well as markers of inflammation, insulin resistance and dysfunctional lipid metabolism - results that demonstrate "peripheral targeted engagement," Didsbury said. (medscape.com)
- The treatment focuses on improving regulation of glucose and lipid metabolism in the brain. (medscape.com)
Uptake9
- A group of scientists from Columbia University in United States have developed a state-of-the-art probing technique that can simultaneously map glucose uptake and incorporation activities in living cells. (rsc.org)
- Its metabolism, including uptake and incorporation, is vital to sustain the energy consumption of living organisms. (rsc.org)
- This technique utilizes two glucose analogues to present the glucose metabolism, the 13 C-labelled 3-O-propargyl-D-glucose (3-OPG- 13 C 3 ) for glucose uptake and the D7-glucose for glucose incorporation. (rsc.org)
- Decoupling of the two peaks allows in-vivo imaging and simultaneous observation of glucose uptake and incorporation in cells with sub-cellular resolution. (rsc.org)
- The blue (panel a) and red (panel b) areas display the regions where glucose incorporation and uptake are taking place, respectively. (rsc.org)
- Two-color mapping images of PC-3 cells highlighting the (a) glucose-incorporation regions (Raman peak: 2133 cm -1 ) and (b) glucose-uptake regions (Raman peak: 2053 cm -1 ). (rsc.org)
- That causes them to boost both their metabolism and their uptake of glucose. (smithsonianmag.com)
- When comparing FTD to HS, glucose uptake was primarily reduced in dorsolateral and ventrolateral prefrontal cortices and in frontopolar and anterior cingulate regions. (nih.gov)
- Here, the function of regulation is quite clear: expressing energy and carbon, that a number around 0.2% would be the right genes at the right time will enable the cell to make the expected, and that the difference is more or less specific to the lac most of the resources within its reach, by maximizing the uptake operon [7]. (lu.se)
Physiology1
- American Journal of Physiology - Endocrinology and Metabolism. (lu.se)
Hepatic glucose production2
- The brain modulates various aspects of metabolism, such as food intake, energy expenditure, insulin secretion, hepatic glucose production and glucose/fatty acid metabolism in adipose tissue and skeletal muscle. (nature.com)
- Unexpectedly, loss or inhibition of Reptin induced an opposite effect on mTORC1 and mTORC2 signalling, with: (1) strong inhibition of hepatic mTORC1 activity, likely responsible for the reduction of hepatocytes cell size, for decreased de novo lipogenesis and cholesterol transcriptional programmes and (2) enhancement of mTORC2 activity associated with inhibition of the gluconeogenesis transcriptional programme and hepatic glucose production. (nih.gov)
Liver15
- Glycogen is a long-term store of glucose produced by the cells of the liver. (wikipedia.org)
- In the liver, the synthesis of glycogen is directly correlated with blood glucose concentration. (wikipedia.org)
- High blood glucose concentration causes an increase in intracellular levels of glucose 6-phosphate in the liver, skeletal muscle, and fat (adipose) tissue. (wikipedia.org)
- Liver cells are freely permeable to glucose, and the initial rate of phosphorylation of glucose is the rate-limiting step in glucose metabolism by the liver. (wikipedia.org)
- Consuming excess fructose ultimately results in an imbalance in liver metabolism, which indirectly exhausts the liver cell's supply of ATP. (wikipedia.org)
- At the end of the exposure, fasting blood glucose and serum insulin were evaluated before epididymal adipose tissue and liver were collected, flow cytometry, quantitative PCR and Western blot were performed at euthanasia. (deepdyve.com)
- Fiber keeps the glucose and other nutrients from getting to the liver so fast and overloading it. (bentrideronline.com)
- The liver tissue plays a major role in energy metabolism, particularly glucose and lipid homeostasis. (hindawi.com)
- Our data suggest that inhibition of AR in the T2DM db/db mice led to significant activation in hepatic PPAR α and significant reductions in serum triglycerides (TG) and hepatic TG, suggesting that under hyperglycemia, AR/the polyol pathway might be greatly upregulated to contribute significantly to the hepatic regulation of TG metabolism and the development of nonalcoholic steatohepatitis (NASH) or nonalcoholic fatty liver disease (NAFLD). (hindawi.com)
- After carbohydrates are duly broken down into glucose, in the duodenum and jejunum of the small intestine, the glucose is absorbed into the bloodstream and taken to the liver, where it is stored or distributed to cells throughout the body for energy. (annecollins.com)
- In this way, the liver regulates blood glucose levels to provide sufficient energy for the body. (annecollins.com)
- For example, excess glucose (a cause of hyperglycemia) is converted in the liver to glycogen (glycogenolysis) in response to the hormone insulin , and stored. (annecollins.com)
- 12 Other important effects of leptin include increase in glucose utilization, inhibition of lipogenesis, stimulation of fatty acid oxidation, and reduction of trigliceride accumulation in liver and skeletal muscles, accounting for leptin's insulin-sensitizing properties. (researchgate.net)
- Glucose is primarily stored as glycogen in muscles and liver. (medscape.com)
- Ingestion of the poison causes a malady referred to as Jamaican vomiting sickness, which involves a disruption of fatty acid metabolism, leading to fatty acid accumulating in the liver. (cdc.gov)
Glycogen7
- Glucose 6-phosphate has role in regulating glycogen synthase. (wikipedia.org)
- The liver's crucial role in controlling blood sugar concentrations by breaking down glucose into carbon dioxide and glycogen is characterized by the negative Gibbs free energy (ΔG) value, which indicates that this is a point of regulation with. (wikipedia.org)
- Allosteric activation by glucose 6-phosphate, which acts as an effector, stimulates glycogen synthase, and glucose 6 phosphate may inhibit the phosphorylation of glycogen synthase by cyclic AMP-stimulated protein kinase. (wikipedia.org)
- between meals), the glycogen is re-converted to glucose (glycogenolysis) in response to messages conveyed by the hormone glucagon , to prevent hypoglycemia. (annecollins.com)
- If glycogen levels are exhausted, glucagon can trigger the formation of glucose from some amino acids (protein) or glycerol (fats) - a process called gluconeogenesis . (annecollins.com)
- Under total fasting conditions, where someone only has water, the body initially uses carbohydrate stores, called glycogen, to maintain blood glucose levels, and for cellular energy production. (theconversation.com)
- With an unavailability of fatty acids, the body resorts to using glucose and glycogen for its energy, which then leads to hypoglycemia. (cdc.gov)
Phosphorylated to glucose 6-phospha2
- glucose is phosphorylated to glucose 6-phosphate during transport across the membrane by ATP-D-glucose 6-phosphotransferase and non-specific hexokinase (ATP-D-hexose 6-phosphotransferase). (wikipedia.org)
- Most of the glucose transported into the lens is phosphorylated to glucose-6-phosphate (G6P) by the enzyme hexokinase. (aao.org)
Plasma glucose4
- Resting energy expenditure (REE), substrate oxidation rates, plasma glucose, free fatty acid, and insulin and leptin levels were measured before and 3, 6, and 12 months after surgery. (unige.ch)
- Serum glucose values are 1.15% lower than plasma glucose values. (medscape.com)
- Morning fasting plasma glucose values are higher than afternoon glucose levels. (medscape.com)
- In heparinized plasma, glucose concentrations are 5% lower than plasma. (medscape.com)
Metabolic7
- Highly coordinated interactions between the brain and peripheral metabolic organs are critical for the maintenance of energy and glucose homeostasis. (nature.com)
- 1 The brain monitors changes in the body energy state by sensing alterations in the plasma levels of key metabolic hormones and nutrients. (nature.com)
- Specialized neuronal networks in the brain coordinate adaptive changes in food intake and energy expenditure in response to altered metabolic conditions ( Figure 1 ). (nature.com)
- Integration of peripheral metabolic signals andthe central nervous system maintains energy homeostasis. (nature.com)
- The polyol pathway is a glucose metabolic shunt that is defined by two enzymatic reactions catalyzed by aldose reductase (AR, AKR1B1, EC1.1.1.21) and sorbitol dehydrogenase (SDH, EC1.1.1.14), respectively [ 1 , 2 ]. (hindawi.com)
- Adipocytes, the key components of the adipose tissue, have unique ability to store excess energy in the form of triglycerides, sense systemic energy demands, and secrete factors (lipids, peptides, cytokines, and adipokines) to regulate other metabolic tissues. (frontiersin.org)
- Iodine Maintains/supports body metabolism and metabolic rate. (bodyscience.com.au)
Regulates3
- Glucavive is one of the best blood sugar managing formulas that help to manage the healthy sugar metabolism , and it regulates mild to moderate sugar levels with its potent ingredients. (ipsnews.net)
- Adipose tissue is a key nutrient-sensing depot that regulates excess energy storage and consumption. (frontiersin.org)
- Protein contributes to the structural and mechanical function of the body, regulates processes in body cells, and is a secondary source of energy. (avivadirectory.com)
Adipose tissue1
Endocrinology and metabolism1
- Trends in Endocrinology and Metabolism. (lu.se)
Anaerobic6
- Phosphorylation is essential to the processes of both anaerobic and aerobic respiration, which involve the production of adenosine triphosphate (ATP), the "high-energy" exchange medium in the cell. (wikipedia.org)
- Lens metabolism maintains a clear lens and derives most of its energy from anaerobic glycolysis. (aao.org)
- The more active of the 2 pathways, anaerobic glycolysis provides most of the high-energy phosphate bonds required for lens metabolism. (aao.org)
- In anaerobic glycolysis, substrate-linked phosphorylation of adenosine diphosphate (ADP) to adenosine triphosphate (ATP) occurs at 2 steps along the pathway from glucose metabolism to lactate. (aao.org)
- Cancer does not cause cells to turn anaerobic, but rather it is stabilized anaerobic (without oxygen) metabolism that is the single cause that turns the normal cells that depend on aerobic metabolism into cancer cells. (essense-of-life.com)
- This process does not use oxygen (anaerobic metabolism). (medscape.com)
Regulation of energy metabolism1
- hence, the physiological circuits implicated in the regulation of energy metabolism must be able to quickly adjust to changes in either side of the equation. (researchgate.net)
Fatty1
- He also showed they were unable to use fatty acids as efficiently for energy, or at all. (theconversation.com)
Glycolysis3
- The chemical equation for the conversion of D-glucose to D-glucose-6-phosphate in the first step of glycolysis is given by: D-glucose + ATP → D-glucose 6-phosphate + ADP ΔG° = −16.7 kJ/mol (° indicates measurement at standard condition) Glycolysis is an essential process of glucose degrading into two molecules of pyruvate, through various steps, with the help of different enzymes. (wikipedia.org)
- In high-glucose conditions, hexokinase becomes inhibited by products of glycolysis, and aldose reductase becomes relatively increased, converting more glucose to sorbitol. (aao.org)
- Glucose is initially used by glycolysis and is converted to pyruvate. (medscape.com)
Nonalcoholic steatohepatitis1
- 2010), nonalcoholic steatohepatitis, impaired hepatic glucose metabolism (Zheng et al. (deepdyve.com)
Aerobic4
- This pathway is much less efficient than the aerobic citric acid cycle (also called the tricarboxylic acid cycle or the Krebs cycle), because only 2 net molecules of ATP are produced for each glucose molecule utilized, whereas the aerobic citric acid cycle produces an additional 36 molecules of ATP from each metabolized glucose molecule (oxidative metabolism). (aao.org)
- however, even this low level of aerobic metabolism produces approximately 25% of the ATP of the lens. (aao.org)
- The proposed cure, as an alternative to protocols that focus on killing the cancer cells, is to restart aerobic metabolism. (essense-of-life.com)
- Thus, during aerobic metabolism, each molecule of glucose can generate 36 ATPs. (medscape.com)
Boost9
- Can Guarana Boost Energy? (vitanetonline.com)
- Can Royal Jelly Really Boost Energy? (vitanetonline.com)
- Here are the best natural phentermine alternatives to boost metabolism and lose weight quickly. (dallasnews.com)
- PhenQ is a natural fat burner that uses a blend of caffeine, capsicum, and nopal to boost metabolism, increase fat burning, and reduce appetite. (timesofisrael.com)
- There are several herbal supplements that can boost metabolism, reduce hunger, and enhance fat burning. (netrition.com)
- Phen24 is one of the newest weight loss pills that operate during the day as well as the night to help boost your metabolism and encourage faster weight loss. (healthcanal.com)
- They are also believed to reduce your appetite and boost your energy levels, which can be beneficial for weight loss. (healthcanal.com)
- Phen24 aims to boost your energy during the day and help improve your sleep at night. (healthcanal.com)
- Its natural ingredients can help boost energy levels and burn excess fat . (healthcanal.com)
Diabetes5
- 2007). Emerging evidence from both epidemiological and experimental studies indicates the adverse consequences of PM2.5 exposure on diabetes, including worsening of whole-body insulin sensitivity, glucose tolerance impairment, lipid accumulation, and glucose metabolism dysfunction (Hwang et al. (deepdyve.com)
- Prickly pear cactus has anti-inflammatory and glucose-reducing properties that help people with type 2 diabetes. (ipsnews.net)
- Intranasal insulin (INS) bypasses the blood-brain barrier, targets the brain, and improves synaptogenesis in rodent models, and memory in adult humans with Alzheimer's disease or type 2 diabetes, without altering the blood levels of insulin or glucose. (healthpartners.com)
- Aims/hypothesis: Using a targeted proteomics approach, we aimed to identify and validate circulating proteins associated with impaired glucose metabolism (IGM) and type 2 diabetes in a Black South African cohort. (lu.se)
- For gestational diabetes testing, parameters are 1 hour after 50 g of glucose and 2 hours after 100 g of glucose. (medscape.com)
Homeostasis2
- Substantial evidence indicates that the brain, particularly the hypothalamus, is primarily responsible for the regulation of energy homeostasis. (nature.com)
- By disrupting circadian timing, bedtime variability may impair glucose metabolism and energy homeostasis. (sciencedaily.com)
Cell Metabolism2
- Cell Metabolism. (monash.edu)
- In a study published in the journal Cell Metabolism earlier this month, scientists at the University of Sydney in Australia shared details of what they described as a "breakthrough" in deconstructing what happens inside a human body during exercise. (smithsonianmag.com)
Healthy glucose3
- 4Life Transfer Factor GluCoach assists your body in maintaining healthy glucose levels-it's your glucose coach! (4life.com)
- It is a supernatural formula that helps to improve blood sugar levels, support healthy glucose metabolism, minimize the blood sugar imbalance and increase energy and alertness . (ipsnews.net)
- These active ingredients then support the healthy glucose metabolism and replenish the vital nutrients to increase energy and focus. (ipsnews.net)
Insulin sensitivity1
- Chromium picolinate can reduce cravings for sugary and high-carbohydrate foods and improve insulin sensitivity and glucose metabolism. (timesofisrael.com)
Amino acids1
- It is required for the metabolism of glucose, amino acids, and lipids. (webmd.com)
Thermogenesis3
- Maintain/support energy production and thermogenesis. (bodyscience.com.au)
- Caffeine is a natural stimulant found in this fat burner that can improve cognitive function, mood, and energy levels while stimulating thermogenesis and aiding in fat loss. (timesofisrael.com)
- Phen24 is the industry's first metabolism-fueling system that supports thermogenesis even while you snooze. (healthcanal.com)
Intolerance2
- We found that Reptin deletion completely rescued pathological phenotypes associated with IR, including glucose intolerance, hyperglycaemia, hyperlipidaemia and hepatic steatosis. (nih.gov)
- 2017). The inhibition of hypothalamic inflammation by intracerebroventricular (ICV) administration of IKK2 inhibitor (IMD-0354) rectified PM2.5-induced glucose intolerance, IR, energy metabolism dysfunction, and attenuated peripheral inflammation in response to PM2.5 exposure (Song et al. (deepdyve.com)
Apoptosis2
- Expression levels of HK2, glucose transporter 1, TXNIP, c‑Myc and mitochondria‑regulated apoptosis pathway proteins were measured through western blotting. (spandidos-publications.com)
- Of the numerous lipid classes implicated in eliciting lipotoxicity, sphingolipid: ceramides are among the most deleterious as they modulate signaling pathways involved in regulating glucose metabolism, triglyceride synthesis, apoptosis, and fibrosis. (frontiersin.org)
Molecule1
- Glucose, by nature, is a small molecule with the ability to diffuse in and out of the cell. (wikipedia.org)
Oxygen3
- In the mid-1800s, Louis Pasteur determined that microorganisms cause the breakdown of glucose in the absence of oxygen (fermentation). (jove.com)
- The kidneys have the highest oxygen and glucose consumption per gram of tissue and are therefore vulnerable to toxins affecting cell energy metabolism. (msdmanuals.com)
- In the presence of oxygen, pyruvate undergoes metabolism by the Krebs cycle in the mitochondria. (medscape.com)
Levels11
- clarification needed] The hexokinase enzyme has a low Michaelis constant (Km), indicating a high affinity for glucose, so this initial phosphorylation can proceed even when glucose levels at nanoscopic scale within the blood. (wikipedia.org)
- This pathway, which is stimulated in the presence of elevated levels of glucose, is involved in the generation of NADPH or reducing power. (aao.org)
- Glucavive, in this review, is an effective natural solution that assists people in naturally reducing their high blood glucose levels without involving any risks. (ipsnews.net)
- Glucavive helps many customers to manage their blood glucose levels and help them to achieve a happy life full of energy. (ipsnews.net)
- It helps decrease glucose levels in the blood. (ipsnews.net)
- It helps to balance insulin and glucose levels in the blood. (ipsnews.net)
- Olive Leaf Extract is a vital source of antioxidants that helps to lower blood glucose and helps to stabilize primary healthy blood sugar levels. (ipsnews.net)
- The mice treated with compound 14 who were fed a normal diet retained a normal weight and blood glucose levels. (smithsonianmag.com)
- Its formula approaches weight loss from all sides, inhibiting fat buildup, increasing energy levels, and making you feel full much longer after you eat. (dallasnews.com)
- It contains natural ingredients promoting fat burning, reducing cravings, and increasing energy levels. (timesofisrael.com)
- For example, the daytime formula aims to give you more energy and improve your mental focus, while the nighttime formula aims to decrease stress levels to promote healthy sleep. (healthcanal.com)
Cellular3
- Because it is soluble in both water and fat, lipoic-acid is a potent antioxidant that supports mitochondrial function, helps protect against oxidative stress and maintains cellular energy. (netrition.com)
- Cellular respiration is the biochemical process that converts 'food energy' (from the chemical bonds of macromolecules) into chemical energy in the form of adenosine triphosphate (ATP). (jove.com)
- Vitamins are required for proper cellular function, growth, metabolism, and development and may be soluble in fat or in water. (avivadirectory.com)
Transporters1
- The acute effects on hippocampal neurochemical profile and transcript mRNA expression of insulin receptor (Insr), glucose transporters (Glut1, Glut4, and Glut8), and poly(ADP-ribose) polymerase-1 (Parp1, a marker of oxidative stress) were determined on P7 using in vivo 1H MR spectroscopy (MRS) and qPCR. (healthpartners.com)
Fructose2
- The phosphorylation of glucose can be enhanced by the binding of fructose 6-phosphate (F6P), and lessened by the binding fructose 1-phosphate (F1P). (wikipedia.org)
- Added sugars: Did you know Sugar is often listed under many terms like fructose/ lactose/glucose/sucrose etc. (dane101.com)
Fasting1
- For fasting glucose testing, collect the blood sample in the morning after an overnight or 8-hour fast. (medscape.com)
Tolerance2
- Then, when the mice fed a high-fat diet were given a single dose of compound 14 every day for seven days, their glucose tolerance improved and they lost roughly 5 percent of their body weight. (smithsonianmag.com)
- For oral glucose tolerance testing, after oral intake of 75 g of glucose, collect blood samples at 1 hour and 2 hours. (medscape.com)
Transcriptional1
- With a minimalist model of metabolism, cell growth and transcriptional regulation in a microorganism, we explore how the interaction between environmental conditions and gene regulation set the growth rate of cells in the phase of exponential growth. (lu.se)
Sugar8
- Phosphorylation of glucose is a key reaction in sugar metabolism. (wikipedia.org)
- When we consume food, our blood glucose naturally rises due to the sugar and carbs. (ipsnews.net)
- Cancerous cells are known to rely on glucose , a type of sugar, for their energy metabolism, rapid growth, and resistance to chemotherapy. (theconversation.com)
- Cancer cells rely on glucose, a type of sugar, for energy metabolism and growth. (theconversation.com)
- HydroxyBurn can also assist sugar metabolism and thyroid hormone production. (bodyscience.com.au)
- Chromium Helps glucose, sugar and carbohydrate metabolism. (bodyscience.com.au)
- Cancer cells use more glucose (sugar) per unit of time than other cells. (essense-of-life.com)
- Sugar metabolism creates acid, which also supports cancer progression. (essense-of-life.com)
Proteins1
- Commenting on the research for Medscape Medical News , Rebecca Edelmayer, PhD, senior director of scientific engagement for the Alzheimer's Association, noted that "the idea behind this treatment is that impaired glucose metabolism in the brain leads to toxic misfolded proteins, including amyloid and tau in people with Alzheimer's disease. (medscape.com)
Appetite3
- These hormones help control appetite, glucose processing and energy metabolism, therefore making sleep a regulator of weight. (adelphi.edu)
- This is due to a number of factors, including appetite loss as the disease progresses, side effects of treatment, and cancer's increased demands on metabolism. (theconversation.com)
- Its application by either the central or peripheral process increases appetite, food intake, adiposity and glucose metabolism [2, 3] . (researchgate.net)
Intake2
- In normal individuals, food intake and energy expenditure are tightly regulated by homeostatic mechanisms to maintain energy balance. (nature.com)
- Energy intake, calculated from self-reported food consumption, was also expressed as AUC. (unige.ch)
Hyperglycemia2
- Neonatal hyperglycemia was associated with abnormal glucose metabolism and microgliosis in the adult hippocampus. (healthpartners.com)
- INS administration during hyperglycemia attenuated these adverse effects and improved energy metabolism in the hippocampus. (healthpartners.com)
Brain6
- Accumulated evidence from genetic animal models suggests that the brain, particularly the hypothalamus, has a key role in the homeostatic regulation of energy and glucose metabolism. (nature.com)
- Here we comprehensively review the above topics, discussing the main findings related to the role of the brain in the homeostatic regulation of energy and glucose metabolism. (nature.com)
- These neurons project to other hypothalamic nuclei and to the nucleus of the solitary tract in the brain stem to control multiple aspects of the homeostatic regulation of energy balance. (nature.com)
- MRS showed 59% higher brain glucose concentration and histochemistry showed microgliosis in the hippocampal subareas in the STZ group. (healthpartners.com)
- Brain glucose was normal in the STZ + INS group. (healthpartners.com)
- 25% of the night, has been shown to provide energy both to the brain and body that allows us to stay alert throughout the day. (adelphi.edu)
NADPH1
- Biochemically, AR catalyzes the rate-limiting reduction of glucose to sorbitol, with the aid of cofactor NADPH. (hindawi.com)
Carbohydrates4
- Thiamine helps turn carbohydrates into energy. (webmd.com)
- It is used to break down carbohydrates and to make energy. (medlineplus.gov)
- This metabolism of carbohydrates is achieved through the secretion of a number of digestive enzymes into the gastrointestinal tract (especially in the duodenum) where they attack carbohydrates and gradually convert them into simple sugars like glucose so they can be absorbed into the blood. (annecollins.com)
- Broken down into glucose through digestion, which is used for energy, carbohydrates are our primary source of energy. (avivadirectory.com)
Clinical2
- Visualization of glucose metabolism is of critical importance for clinical diagnostics and fundamental biological researches. (rsc.org)
- Metabolism: Clinical and Experimental. (monash.edu)
Consumption1
- Thioredoxin‑interacting protein (TXNIP) competes with c‑Myc to reduce glucose consumption in tumor cells to restrain cell proliferation. (spandidos-publications.com)
Carbohydrate2
- As the carbohydrate passes further into the intestine, the enzymes maltase , lactase and sucrase chop maltose, lactose and sucrose into smaller bits, more easily absorbed, which are eventually converted to glucose and absorbed through the intestinal walls into the bloodstream. (annecollins.com)
- The glycolytic pathway converts one hexose (a six-carbon carbohydrate such as glucose) into two triose molecules (three-carbon carbohydrate) such as pyruvate, to produce a net total of two molecules of ATP (four produced, two consumed) and two molecules of nicotinamide adenine dinucleotide (NADH). (jove.com)
Variability1
Nutrients1
- Nutrients are compounds found in food that are required for essential body functions, as they are used for energy, growth, reproduction, and the prevention of disease. (avivadirectory.com)
Production5
- In the lens, energy production largely depends on glucose metabolism. (aao.org)
- Doctor's Best Stabilized R-Lipoic-Acid helps support glucose metabolism and energy production. (netrition.com)
- When these stores are depleted, protein from muscle is used to produce new glucose , and fat stores start to be used for energy production. (theconversation.com)
- It can be used as a pre-workout for long-lasting energy production. (bodyscience.com.au)
- Glucose is a monosaccharide and is a primary metabolite for energy production in the body. (medscape.com)
Mice2
- The researchers tested the compound 14 on two groups of mice, one fed a normal diet while the other was fed a high-fat diet, which made them obese and glucose intolerant-a sign of prediabetes . (smithsonianmag.com)
- But the mice fed a high-fat diet who were given a single dose of the compound had their blood glucose level drop to near normal. (smithsonianmag.com)
Concentration2
- Relative to the control (CONT) group, mean blood glucose concentration was higher from P3 to P6 in the STZ and STZ + INS groups. (healthpartners.com)
- At adulthood, blood glucose concentration in the fed state was higher in the STZ and STZ + INS groups. (healthpartners.com)
Protein2
- Neuropeptide Y/agouti-related protein- and proopiomelanocortin-producing neurons in the hypothalamic arcuate nucleus primarily sense the body energy state. (nature.com)
- This one summarized the state of exercise pill research, pointing out that much of it has focused on activating a particular protein that not only plays a key role in maintaining the body's energy balance, but also can cause changes in muscle cells similar to what occurs with exercise. (smithsonianmag.com)
Body's1
- Coming in saturated and unsaturated forms, fats are our body's chief source of stored energy. (avivadirectory.com)