• Disruption of the Tie2 pathway in mice by conditional knockout early in postnatal development results in failure of the formation of Schlemm's canal, associated with increased IOP and with retinal and optic nerve pathology resembling human congenital glaucoma. (aerpio.com)
  • The role of vascular factors in the pathogenesis of glaucoma has recently received much attention based on animal experiments and epidemiological studies. (clinicaltrials.gov)
  • These findings lend support to the hypothesis that a decreased CSF pressure resulting in an increased translaminar pressure difference may contribute to the pathogenesis of glaucoma. (molvis.org)
  • There are reports of a difference in the rates of glaucoma and OHT between men and women, but because there are also conflicting reports, a firm conclusion has not been established. (fiteyes.com)
  • Higher rates of glaucoma have also been reported for Inuit populations, compared to white populations, in Canada and Greenland. (wikipedia.org)
  • However, terms can sometimes get confusing as it may involve an overlap with other forms of glaucoma. (fiteyes.com)
  • A data search and personal investigations assume a limited role of mineralocorticoids for the development of glaucoma. (hindawi.com)
  • A recent 4 year study showed that blacks with OHT had a 3-4 times greater likelihood of then developing glaucoma. (fiteyes.com)