• The delayed nature of these secondary injury mechanisms provides a window for therapeutic intervention to prevent progression of tissue damage and for improved outcome [ 5 ]. (alliedacademies.org)
  • Secondary outcomes were pain at rest and on activity, swelling, and physical activity at baseline and at one, two, three, and four weeks after injury. (bmj.com)
  • Secondary objectives are thromboembolic event rate, perioperative blood loss, postoperative anemia, intra- and postoperative blood transfusion rate, and clinical outcome. (springer.com)
  • Although research is ongoing, no drugs have yet been proven to reduce secondary injury and improve functional outcome of TBIs ( 14 ). (cdc.gov)
  • This has led to the development of better monitoring and treatment methods aimed at preventing this secondary injury and improving the outcome for patients who have suffered a head injury. (pbs.org)
  • Secondary outcomes included death, focal neurologic abnormalities, hearing loss and clinically significant gastrointestinal bleeding. (cmaj.ca)
  • Approach to Human Subject Protection and Patient Safety The National Institutes of Health Stroke Scale (NIHSS) is a systematic assessment tool that provides a. (buonasera-giuro.pw)
  • The global odds ratio for improvement included improvements in the Barthel Index (OR 1.6, 95 percent CI 1.1 to 2.5), modified Rankin Scale (mRS) (OR 1.7, 95 percent CI 1.1 to 2.5), Glasgow Outcome Scale (GOS) (OR 1.6, 95 percent CI 1.1 to 2.5) and the National Institute of Health Stroke Scale (NIHSS) (OR 1.7, 95 percent CI 1.0 to 2.8). (ahrq.gov)
  • Clinical outcome evaluated by NIH Stroke Scale(NIHSS)scores. (strokecenter.org)
  • 0.001), and had better outcomes. (nih.gov)
  • A trend towards better outcomes was observed with minocycline, especially in those patients who survived the initial day in hospital. (biomedcentral.com)
  • In addition to resulting in better outcomes, aggressive care required lower total costs than routine care ($1,264,000 versus $1,361,000 for the average 20-year-old), a result of lower costs associated with long-term nursing care and lost productivity. (medpagetoday.com)
  • HPeV encephalitis is associated with neurodevelopmental sequelae despite reassuring short-term outcomes. (aappublications.org)
  • If IAR occurs, balloon-assistance is helpful in obtaining rapid hemostasis resulting in better short-term outcomes. (ajnr.org)
  • At late follow-up, 76% of the patients had good outcomes (Glasgow Outcome Scale scores of 1 and 2), 5% had poor outcomes (Glasgow Outcome Scale scores of 3 and 4), and 18% had died. (nih.gov)
  • Finally, there was no statistically significant correlation between sarcopenia or obesity markers and duration of mechanical ventilation, ICU length of stay or neurologic outcome. (springer.com)
  • Nevertheless, we could not demonstrate any significant effect of abdominal fat and muscle tissue parameters on the course of treatment, in particular the duration of mechanical ventilation, ICU length of stay and neurologic outcome. (springer.com)
  • These factors, as well as the neurologic and medical condition of the patient, determine the course of treatment and may also influence the outcome. (medscape.com)
  • The CASTOR study will help to find favorable cost-utility treatment regimens for AIS and improve the overall treatment outcome of Chinese patients with AIS. (biomedcentral.com)
  • Small numbers, quasi randomisation (according to arrival date), study focussed on ICP and biomarkers to show neuroprotective effect of hypothermia rather than clinically relevant outcomes. (bestbets.org)
  • Participants completed self-report measures related to functional outcomes, psychological health, post-injury symptoms, and sleep, and underwent a neuroimaging session that included DWI. (frontiersin.org)
  • However, there is little data available regarding the relationship between functional outcomes and the anatomical features of renal tumours treated by RAPN. (thefreedictionary.com)
  • PDT has already shown significant potential for improving cancer treatment because it offers strictly focused application, biocompatibility with other forms of treatment, the option for repeated use, excellent cosmetic or functional outcomes and fast recovery. (thefreedictionary.com)
  • While there is a broad consensus that appropriate prehospital treatment is crucial for a favorable neurological outcome, evidence to support currently applied treatment strategies is scarce. (eur.nl)
  • No undesirable effects attributable to HI were observed and 4 patients survived 90 days with a favorable neurological outcome. (go.jp)
  • The scale runs from 1 (dead), 2 (vegetative state), 3 (severely disabled), 4 (moderately disabled), and 5 (good recovery). (medpagetoday.com)
  • Originally, the primary endpoint of the study was an unfavorable outcome -- a composite of death, vegetative state, or severe disability as evaluated on the Extended Glasgow Outcome Scale -- six months after the injury, the researchers noted. (medpagetoday.com)
  • Study Protocol: BRAIN-PROTECT is the acronym for BRAin INjury: Prehospital Registry of Outcome, Treatments and Epidemiology of Cerebral Trauma. (eur.nl)
  • Prehospital epidemiology, interventions, medication strategies, and nonmedical factors that may affect outcome are studied. (eur.nl)
  • A scale that assesses current neurological awareness of the environment, and recovery and disability in all types of brain injury. (thefreedictionary.com)
  • The Glasgow Outcome Scale (GOS) is the most widely used outcome measure after traumatic brain injury, but it is increasingly recognized to have important limitations. (nih.gov)
  • The Glasgow Outcome Scale (GOS) and its most recent revision, the GOS-Extended (GOS-E), provide the gold standard for measuring traumatic brain injury (TBI) outcome. (semanticscholar.org)
  • The aim of this study was to examine the relationship between early arterial oxygenation thresholds and long-term outcome after severe traumatic brain injury (TBI). (thejns.org)
  • Background Medical complications after severe traumatic brain injury (S-TBI) may delay or prevent transfer to rehabilitation units and impact on long-term outcome. (bmj.com)
  • The Center for Outcome Measurement in Brain Injury. (tbims.org)
  • CONCLUSION: This study contributes to our understanding of the relationship between clinical descriptors of acute TBI, the extent of injury-related chronic brain changes and neurological outcome. (harvard.edu)
  • The authors acknowledged that the analysis was limited by the large number of assumptions that were made and by the lack of age-specific outcomes in patients treated aggressively for severe traumatic brain injury. (medpagetoday.com)
  • The BRAIN-PROTECT study therefore aims to identify prehospital treatment strategies associated with beneficial or detrimental outcomes. (eur.nl)
  • To compare the predictive values of clinical examinations combined with the recordings of Electroencephalography (EEG) and Brainstem Auditory-Evoked Potentials (BAEP) and computed tomography (CT) of the brain in the evaluation of coma outcome in children. (omicsonline.org)
  • Favourable outcome was strongly related to normally visualize basal cisterns in CT brain (p=0.002), normal/ borderline EEG activity (p=0.03) and normal BAEP waves (p=0.009). (omicsonline.org)
  • The Glasgow Coma Scale (GCS) has several important limitations as a predictor of survival in the general critically ill population while CT brain is mostly important for diagnostic rather than prognostic factor in comatosed children. (omicsonline.org)
  • Outcome of moderate to severe traumatic brain injury (TBI) includes impaired emotion regulation. (jove.com)
  • Background: Valid and relevant estimates of health state preference weights (HSPWs) for Glasgow Outcome Scale (GOS) categories are a key input of economic models evaluating treatments for traumatic brain injury (TBI). (openaire.eu)