AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and Occupations
Salivary Gland NeoplasmsAdenocarcinomaMammary Neoplasms, AnimalSalivary GlandsMammary Glands, AnimalExocrine GlandsSubmandibular GlandAdenocarcinoma, MucinousLung NeoplasmsPancreatic NeoplasmsParotid GlandEsophageal NeoplasmsAdenocarcinoma, PapillaryBarrett EsophagusCarcinoma, Pancreatic DuctalStomach NeoplasmsAdenocarcinoma, Bronchiolo-AlveolarSweat GlandsSebaceous GlandsImmunohistochemistrySublingual GlandHarderian GlandCardiaAdrenal GlandsTumor Markers, BiologicalColonic NeoplasmsEsophagogastric JunctionSalivary Glands, MinorNeoplasm StagingSalivary Gland DiseasesPrognosisLacrimal ApparatusKeratin-7Gene Expression Regulation, NeoplasticCell Line, TumorParathyroid GlandsMeibomian GlandsMammary Neoplasms, ExperimentalCarcinoma, Squamous CellBrunner GlandsEndometrial NeoplasmsNeoplasms, Multiple PrimaryPrecancerous ConditionsApocrine GlandsScent GlandsProstatic NeoplasmsIntestinal NeoplasmsSubmandibular Gland DiseasesAdenomaMetaplasiaImmunoenzyme TechniquesTumor Cells, CulturedDuodenal NeoplasmsNeoplasm InvasivenessSubmandibular Gland Neoplasms
TumorsMajor salivary glandsCarcinomasNeoplasmsApocrineCancers are adenocarcinomasGastricAdenomaArise in the submandibularProstate glandTreatment of salivary glandAnal sacProstatic acinar adenocarcinomaCeruminousMetastaticCarcinoma of the prostateSubmandibular glandsMucus-secretParotidLacrimal glandSublingualAnatomyMammary adenocarcinomaEsophageal adenocarcinomaSecreteSituPathologyUpper aerodigestiveTumor TypeMalignancyDuctalCancerPeriurethralNeoplasmSize of the glandTissueHigh-grade adenocarcinomaCribriformMucosalBartholinEpithelialBasal cellAdenoidCells of the prostateHistologicThyroid glandSGTs
Tumors19
  • The most common malignant tumor of the perianal region is the anal sac (gland) carcinoma accounting for 16.5% of all perianal tumors. (livs.org)
  • Here, we describe two cases of patients suffering of sudden hearing loss and ipsilateral facial hemiparesis due to tumors arising from the ceruminous glands with primary intracranial involvement and subsequent middle ear infiltration. (peertechzpublications.com)
  • Salivary gland tumors (SGTs) are uncommon and represent 2-3% of head and neck neoplasms. (medscape.com)
  • Depending on the location of the gland, they can present with nerve compression symptoms when patients are seen later in the course with larger tumors. (medscape.com)
  • Ceruminous gland tumors are best visualized in a clean ear using a video otoscope. (merckvetmanual.com)
  • Deep en-bloc biopsies of the same tissue are often reported correctly as tumors. (merckvetmanual.com)
  • Tumors of the Ear Canal in Dogs Tumors may develop from any of the structures lining or supporting the ear canal, including the outer layer of skin, the glands that produce earwax and oil, or any of the bones, connective tissues. (merckvetmanual.com)
  • Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
  • Two year feeding and inhalation studies with animals indicated the chemical to be carcinogenic, producing tumors of the central nervous system (CNS), cerebral tumors, squamous cell neoplasms of the Zymbal gland, adenocarcinoma of the small intestine and large intestine, along with numerous benign tumors. (cdc.gov)
  • Other findings included papillomata in the stomach, hemangioma of the kidney, fibroadenomas of the mammary gland, benign tumors of the uterus, and tumors of the ear canal. (cdc.gov)
  • Imaging studies of the salivary glands are usually unnecessary for the assessment of small tumors within the parotid or submandibular gland. (medscape.com)
  • Computed tomography (CT) scanning or magnetic resonance imaging (MRI) is useful for determining the extent of large tumors, for evaluating extraglandular extension, for determining the actual depth of parotid tumors, and for discovering other tumors in one gland or in the contralateral gland. (medscape.com)
  • However, no difference exists between the specificities and sensitivities of CT scanning and MRI for the location or amount of infiltration of tumors in the parotid gland. (medscape.com)
  • This imaging is particularly valuable for salivary gland neoplasms in the paranasal sinus, where skull-base or intracranial extension may alter the resectability of the tumors. (medscape.com)
  • Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain complex and challenging problems for the head and neck surgeon. (medscape.com)
  • Salivary gland neoplasms make up 6% of all head and neck tumors. (medscape.com)
  • An estimated 700 deaths (0.4 per 100,000 for males and 0.2 per 100,000 for females) related to salivary gland tumors occur annually. (medscape.com)
  • Almost half of all submandibular gland neoplasms and most sublingual and minor salivary gland tumors are malignant. (medscape.com)
  • Successful diagnosis and treatment of patients with salivary gland tumors require a thorough understanding of tumor etiology, biologic behavior of each tumor type, and salivary gland anatomy. (medscape.com)
Major salivary glands2
Carcinomas5
  • However, adenocarcinomas of the lung, and occasional breast, transitional cell and pancreatic carcinomas had moderate or high levels of HE4 expression. (nature.com)
  • Sarcomas and basal cell carcinomas with underlying adenocarcinoma also occur. (msdmanuals.com)
  • Excretory stem cells give rise to squamous cell and mucoepidermoid carcinomas, while intercalated stem cells give rise to pleomorphic adenomas, oncocytomas, adenoid cystic carcinomas, adenocarcinomas, and acinic cell carcinomas. (medscape.com)
  • Comprehensive genomic profiles of metastatic and relapsed salivary gland carcinomas are associated with tumor type and reveal new routes to targeted therapies. (cdc.gov)
  • It is rare in other salivary gland carcinomas. (medscape.com)
Neoplasms14
Apocrine4
  • An anal sac adenocarcinoma is an uncommon and aggressive malignant tumor found in dogs that arises from the apocrine glandular tissue of anal sac. (wikipedia.org)
  • Apocrine gland anal sac adenocarcinomas first appear as small lumps associated with one of the anal sacs (rarely bilateral), but they can grow to a large size. (wikipedia.org)
  • Apocrine gland anal sac adenocarcinomas also have a tendency to metastasize to the regional lymph nodes, spleen, and eventually lungs and, less commonly, bones. (wikipedia.org)
  • The most common type is known as anal sac adenocarcinoma or apocrine gland anal sac adenocarcinoma (AGASACA). (cornell.edu)
Cancers are adenocarcinomas3
Gastric2
Adenoma3
Arise in the submandibular1
Prostate gland4
  • It develops in the gland cells that line the prostate gland. (webmd.com)
  • This kind starts in the cells that line the ducts (or tubes) of the prostate gland. (webmd.com)
  • No specific macroscopic findings have been reported, although large xanthomas may appear as yellowish foci on cut sections of the prostate gland. (medscape.com)
  • We would encourage other hospital pathologists to review periodically the uniformity of diagnoses in an attempt to improve their practices in prostate gland pathology. (who.int)
Treatment of salivary gland1
  • F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) scanning can be used to plan treatment of salivary gland malignancies by detecting lymph node metastases that require a neck dissection or by finding distant metastases that may not have caused abnormalities in routine blood work. (medscape.com)
Anal sac2
  • Anal sac adenocarcinomas are often suspected due to location (palpable masse in anal sac) and behavior, but a biopsy and histopathology is necessary for a definitive diagnosis. (wikipedia.org)
  • Anal sac gland adenocarcinoma in the dog: 14 cases. (oregonstate.edu)
Prostatic acinar adenocarcinoma2
  • Three of our cases were morphologically consistent with prostatic acinar adenocarcinoma with variable cribriform, fused, and poorly formed glands, analogous to Gleason score 4+4=8. (johnshopkins.edu)
  • Prostate xanthomas may mimic high-grade prostatic acinar adenocarcinoma with foamy cytoplasm, as well as adenocarcinoma with posthormonal therapy effect, particularly androgen deprivation therapy. (medscape.com)
Ceruminous2
  • Adenocarcinoma of the ceruminous glands is a rare malignancy arising from the glands of the external auditory canal. (peertechzpublications.com)
  • Radiation therapy can be used to treat excised ceruminous gland adenocarcinomas in dogs and cats, with a 56% 1-year survival rate reported. (merckvetmanual.com)
Metastatic4
Carcinoma of the prostate1
  • Foamy gland carcinoma of the prostate features cells with abundant finely vacuolated cytoplasm and pyknotic hyperchromatic nuclei. (medscape.com)
Submandibular glands1
  • The submandibular glands produce both serous and mucous saliva. (medscape.com)
Mucus-secret2
  • Editor's note: Adenocarcinoma is a type of cancer that can form in mucus-secreting glands throughout the body. (cdc.gov)
  • Adenocarcinoma begins in cells that make up mucus-secreting glands in the bladder. (mayoclinic.org)
Parotid6
  • By approximately 1850, the focus shifted toward dissection and the intimate relation between the facial nerve and the parotid gland. (medscape.com)
  • In 1958, Beahrs and Adson eloquently described the relevant anatomy and surgical technique of current parotid gland surgery. (medscape.com)
  • [ 7 ] They stressed surgical landmarks for avoiding injury to the main trunk and branches of the facial nerve and advocated complete removal of the superficial portion of the parotid gland for noninvasive lesions confined to that portion of the gland. (medscape.com)
  • The parotid gland is situated in the musculoskeletal recess formed by portions of the temporal bone, atlas, and mandible, along with their related muscles. (medscape.com)
  • At rest, the parotid glands, located anterior to the ears, produce approximately 25% of oral saliva. (medscape.com)
  • [ 7 ] age-related decline in saliva output was found to occur in the stimulated parotid, unstimulated submandibular/sublingual, and stimulated submandibular/sublingual glands. (medscape.com)
Lacrimal gland5
  • Primary ductal adenocarcinoma of the lacrimal gland with sarcomatoid d" by Alise J. Aucoin, Harshvardhan Chawla et al. (lsuhsc.edu)
  • We describe a case of primary ductal adenocarcinoma of the lacrimal gland with novel histopathological characteristics corresponding to a biphasic growth course and provide a comprehensive genomic profile of this malignancy. (lsuhsc.edu)
  • This represents the first report of sarcomatoid differentiation in primary ductal adenocarcinoma of the lacrimal gland, which may incite hyperacute progression. (lsuhsc.edu)
  • An orbital computerized tomography scan showed an inhomogeneous mass in the right lacrimal gland region without bone involvement. (eyehospital.nl)
  • Whole Exome Sequencing of Lacrimal Gland Adenoid Cystic Carcinoma. (cdc.gov)
Sublingual3
  • The sublingual glands, under the tongue, produce about 5% of the total oral saliva. (medscape.com)
  • The parotids produce the most fluid saliva, as they are composed of serous acini, with the sublingual gland producing mucus from mucous acini. (medscape.com)
  • Additional research suggests that changes may occur in the viscoelasticity of saliva with aging, particularly in saliva produced by the submandibular and sublingual glands. (medscape.com)
Anatomy1
  • [ 1 ] This article reviews basic salivary anatomy and physiology, several important diseases affecting the glands, salivary constituents as measures of health, trends in diagnosis, and the management of xerostomia and drooling. (medscape.com)
Mammary adenocarcinoma2
Esophageal adenocarcinoma4
  • Patients with BE are at an increased risk for development of esophageal adenocarcinoma [ 13 ] and the incidence of esophageal adenocarcinoma has increased by 300-500% in white men in the last 30 years [ 14 , 15 ]. (hindawi.com)
  • The feasibility of OCT for carrying out in vivo real time imaging of Barrett's esophagus, high grade dysplasia and esophageal adenocarcinoma has been well demonstrated (Figures 1 , 2 , and 3 ). (hindawi.com)
  • High grade dysplasia and esophageal adenocarcinoma images exhibited more heterogeneous structures corresponding to irregular, heterogeneous tissue morphology from distorted and cribriform or villiform glandular architecture. (hindawi.com)
  • Now, a team of researchers has identified an inherited mutation in a gene linked to a highly lethal cancer of what is commonly known as the food pipe, called esophageal adenocarcinoma (EAC). (sciencedaily.com)
Secrete2
Situ2
  • Cases of endocervical adenocarcinoma (n = 90), adenocarcinoma in situ (AIS) (n = 32), benign glandular lesions (n = 36), and normal endocervical mucosa (n = 5) were selected from Stony Brook Medicine and the University of Massachusetts from 2002 to 2013. (medscape.com)
  • Although p16 INK4a has been well established as sensitive and accurate diagnostic biomarker for endocervical adenocarcinoma in situ and invasive adenocarcinoma in histologic sections and in cervical cytology specimens, clinical and diagnostic features alone have limited power to predict the survival of patients with endocervical adenocarcinoma. (medscape.com)
Pathology3
  • We describe the histologic, immunohistochemical, and clinical findings of 4 patients with Skene's gland adenocarcinoma retrieved from the Johns Hopkins Urologic Pathology Consult Service from 1984 to 2017. (johnshopkins.edu)
  • Tregnago, AC & Epstein, JI 2018, ' Skene's Glands Adenocarcinoma: A Series of 4 Cases ', American Journal of Surgical Pathology , vol. 42, no. 11, pp. 1513-1521. (johnshopkins.edu)
  • Significant abnormality or disease of the salivary glands, such as that associated with Sjögren syndrome or neoplasm, necessitates additional evaluation by an otolaryngologist or an otolaryngologist/head and neck surgeon for comprehensive treatment of the gland pathology itself. (medscape.com)
Upper aerodigestive2
  • The salivary glands exist as larger named "major" glands and also as many widely dispersed "minor" glands that exist throughout the upper aerodigestive submucosa (ie, palate, lip, pharynx, nasopharynx, larynx, and parapharyngeal space). (medscape.com)
  • The minor salivary glands comprise 600-1000 small glands distributed throughout the upper aerodigestive tract. (medscape.com)
Tumor Type1
  • In the multicellular theory, each tumor type is associated with a specific differentiated cell of origin within the salivary gland unit. (medscape.com)
Malignancy2
  • That is, as the size of the gland decreases, the incidence of malignancy of a tumor in the gland increases in approximately these proportions. (medscape.com)
  • Mucoepidermoid carcinoma is the most common salivary gland malignancy in children. (medscape.com)
Ductal1
Cancer10
  • Parathyroid cancer is a rare cancer that usually affects people in their forties or fifties and occurs in one of the four parathyroid glands. (medlineplus.gov)
  • In these cases, the cancer is described as hormonally functional because the parathyroid glands are producing excess hormone. (medlineplus.gov)
  • In most cases of parathyroid cancer, these genetic changes are acquired during a person's lifetime and are present only in certain cells in the parathyroid glands . (medlineplus.gov)
  • A cancer that develops in gland-forming tissue. (ucsfhealth.org)
  • Since it is so rare, they did not know what to call it, so they called it sweat gland cancer. (cancer.org)
  • She said that I had aggressive form of cervical cancer, an adenocarcinoma, which ultimately turned out to be Stage 1B1 cervical cancer. (cdc.gov)
  • 2 Cancer of gland cells is known as adenocarcinoma . (cancerquest.org)
  • This type of stomach cancer develops in gland forming cells in the stomach lining. (utah.edu)
  • Cervical cancer has multiple histologic subtypes, with squamous cell carcinoma (SCC) accounting for approximately 75% of cases and invasive adenocarcinoma accounting for 10% to 15% of cases. (medscape.com)
  • [ 5 ] It has been shown that histologic type is an independent prognostic factor in cervical cancer, with adenocarcinoma subtypes being associated with a poorer prognosis compared with SCC. (medscape.com)
Periurethral5
  • Skene's (periurethral) gland carcinoma is a rare neoplasm accounting for less than 0.003% of all genital tract malignancies in females. (nih.gov)
  • Generally, adenocarcinomas of the female urethra are assumed to arise from the periurethral glands, the female homologue of the prostate. (nih.gov)
  • Perhaps this signifies different biologic processes in the development of Skene's/periurethral and urethral adenocarcinomas in females. (nih.gov)
  • Therefore, preoperative and postoperative monitoring of serum PSA titers in patients with adenocarcinomas of the female urethra or periurethral glands (or both) should be considered. (nih.gov)
  • Skene's (periurethral) gland adenocarcinoma is very rare, with only 7 cases reported in the literature. (johnshopkins.edu)
Neoplasm2
  • In some countries, maxillofacial surgeons are also involved in the primary treatment of neoplasm involving the salivary glands. (medscape.com)
  • PLGA is a malignant salivary gland neoplasm that exhibits low tendency for aggressive behavior and usually presents as a non-tender nodule. (bvsalud.org)
Size of the gland1
  • A good rule of thumb is that the likelihood of an SGT being malignant is inversely proportional to the size of the gland from which it originates. (medscape.com)
Tissue3
  • Fig. 2: Establishment of snake venom gland organoids from primary tissue. (nature.com)
  • Tissue section of human prostate containing adenocarcinoma that has been immunostained for the cell-surface antigen CD75s. (cellimagelibrary.org)
  • Using tissue microarrays and full tissue sections of normal and 448 neoplastic tissues, HE4 immunoreactivity was found in normal glandular epithelium of the female genital tract and breast, the epididymis and vas deferens, respiratory epithelium, distal renal tubules, colonic mucosa, and salivary glands, consistent with HE4 gene expression. (nature.com)
High-grade adenocarcinoma1
  • Histopathology demonstrated high-grade adenocarcinoma with a well-differentiated glandular component alongside a poorly differentiated sarcomatoid region. (lsuhsc.edu)
Cribriform1
Mucosal2
  • A case of Skene's gland adenocarcinoma without mucosal urethral involvement is presented. (nih.gov)
  • They learned CAV3 is normally present in specialized cells -- called mucosal glands -- which are typically found beneath the surface of esophagus. (sciencedaily.com)
Bartholin3
  • Bartholin gland adenocarcinoma. (clevelandclinic.org)
  • all may originate in Bartholin glands. (msdmanuals.com)
  • Bartholin Gland Cyst and Bartholin Gland Abscess Bartholin gland cysts are the most common large vulvar cysts. (msdmanuals.com)
Epithelial1
  • K17 was not detected in the epithelial cells of benign glandular lesions, but groups of cuboidal cells, residing beneath the epithelial layer of benign glands, were frequently positive for K17, especially in cases of microglandular hyperplasia. (medscape.com)
Basal cell1
  • Coexisting foamy and nonfoamy adenocarcinoma with glandular differentiation devoid of basal cell lining is helpful in clarifying their malignant nature. (medscape.com)
Adenoid1
Cells of the prostate1
  • These cancers start in the gland cells of the prostate. (webmd.com)
Histologic1
Thyroid gland1
  • A differentiated thyroid gland carcinoma that has_material_basis_in follicular cells. (jax.org)
SGTs1
  • SGTs usually manifest as an enlargement or growth of the affected gland. (medscape.com)