AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceNamed GroupsHealth CareGeographicals
EclampsiaHypertension, Pregnancy-InducedPre-EclampsiaPregnancy Complications, CardiovascularPregnancyHypertensionHELLP SyndromePregnancy OutcomeMagnesium SulfateUterine ArteryHypertension, PulmonaryFertility AgentsPregnancy Trimester, FirstPregnancy ComplicationsBlood PressureGestational AgePregnancy TrimestersMaternal MortalityRisk FactorsPregnancy Trimester, SecondSaskatchewanBlood Pressure Monitoring, AmbulatoryFetal Growth RetardationPregnancy Trimester, ThirdProspective StudiesHypertension, RenalInfant, NewbornDiabetes, GestationalInfant, Small for Gestational AgeHypertension, PortalCase-Control StudiesParityPuerperal DisordersPremature BirthAntihypertensive AgentsIncidencePregnancy ProteinsVascular Endothelial Growth Factor Receptor-1Retrospective StudiesHypertension, RenovascularDiastoleBirth WeightCohort StudiesHypertension, MalignantPosterior Leukoencephalopathy SyndromeUltrasonography, PrenatalAbruptio PlacentaeSleep Apnea SyndromesLogistic ModelsHypertensive EncephalopathyEncyclopedias as TopicPlacentaTrophoblastsEndothelium, VascularPlacental Circulation
Fetal growth restMaternalHELLPCardiovascular diseaseObstetricPrevalence of HypertensionAssociated with preeclampsiaDiabetes mellitusSeizuresHypertensive disorders of pregnancyPostpartumGestation hypertensionPregnantProteinuriaOutcomesPreterm birth10th percentileSmall forMetabolicIncreases the riskPrepregnancyOccursResearchersPractice BulletinPreventionMildWomenACOGPregnanciesPlacentaOnsetRiskWeeks of pregnancyDysfunctionUsually fatalDiagnosisLogistic regressionSevere featuresExcessPrenatalPrematureHighIndicatorsOccurMothers
Fetal growth rest2
  • 2020) Pathological processes in the uterine wall decidua in preeclampsia and fetal growth restriction. (ntnu.edu)
  • Taking tolcapone in mid-gestation barely caused embryo lethality, however, the mice developed preeclampsia-like phenotypes, including maternal hypertension, proteinuria and fetal growth restriction. (biorxiv.org)
Maternal11
  • This may have implications for improving upon the "modest" predictive ability of clinical risk factors for HDPs, the investigators suggested, citing existing first-trimester screening algorithms such as the U.K. Fetal Medicine Foundation preeclampsia model based on maternal history and biomarkers. (medpagetoday.com)
  • The aim of this study was to determine whether the risk remains after consideration of maternal characteristics and superimposed pre-eclampsia. (nih.gov)
  • Physiologically, research has linked pre-eclampsia to the following physiologic changes: alterations in the interaction between the maternal immune response and the placenta, placental injury, endothelial cell injury, altered vascular reactivity, oxidative stress, imbalance among vasoactive substances, decreased intravascular volume, and disseminated intravascular coagulation. (wikipedia.org)
  • Phillips-Bell G, Holicky A, Macdonald M, Hernandez L, Watson A, Dawit R. Collaboration Between Maternal and Child Health and Chronic Disease Epidemiologists to Identify Strategies to Reduce Hypertension-Related Severe Maternal Morbidity. (cdc.gov)
  • At the Florida Department of Health, MCH programs examine how hypertensive disorders affect maternal morbidity and mortality, and chronic disease programs focus on how hypertension affects the general population of men and women. (cdc.gov)
  • We described an example of MCH and chronic disease staff members collaborating to develop a meaningful program indicator - hypertension-related severe maternal morbidity - and potential data-to-action strategies to integrate efforts. (cdc.gov)
  • We collaborated to assess hypertension-related severe maternal morbidity (H-SMM) and hypertensive disorders (preexisting hypertension, gestational hypertension, and preeclampsia) among women at delivery of their live birth to help determine the burden on health care systems in Florida. (cdc.gov)
  • In this study, researchers used a genome wide analysis study (GWAS) method to study maternal DNA variants and preeclampsia or gestational hypertension (new onset high blood pressure without features related to preeclampsia). (preeclampsia.org)
  • Given that "31-35% of preeclampsia predisposition has been attributed to maternal genetics", genetic analyses to find specific loci associated with the disorder could help to predict at-risk patients. (preeclampsia.org)
  • Preeclampsia is a major cause of maternal and fetal morbidity and mortality. (ahajournals.org)
  • Obstetric haemorrhage, gestational hypertension, sepsis and active-phase cardiac arrest were reported as the most common causes of maternal death. (who.int)
HELLP3
Cardiovascular disease2
Obstetric3
  • ICD-9 codes for pre-existing medical conditions, medical events, and obstetric complications utilized to identify cases in the NIS 2000 - 2009. (cdc.gov)
  • Kaplan-Meier curves demonstrating the effect of gestational age at the time of severe acute respiratory syndrome coronavirus 2 infection on secondary obstetric outcomes. (cdc.gov)
  • Gestational hypertension disorders accounted for more than half (57.7%) of obstetric indications, with eclampsia being the cause in half of these cases 8 . (bvsalud.org)
Prevalence of Hypertension5
  • Objectives: This study determined the prevalence of hypertension and its associated factors among patients attending the HIV clinic at the Korle-Bu Teaching Hospital (KBTH). (bvsalud.org)
  • The prevalence of hypertension was estimated among study participants, and socio-demographic, lifestyle, anthropometric, metabolic and HIV/ART-related factors associated with hypertension were determined by logistic regression modelling. (bvsalud.org)
  • Results: The prevalence of hypertension was 36.7%, and the factors associated with hypertension were increasing age, positive family history of hypertension, minimal exercising, current BMI ≥25.0 kg/m2 , total cholesterol level ≥5.17 mmol/L, exposure to anti-retroviral therapy (ART) and increasing duration of ART exposure. (bvsalud.org)
  • Conclusions: This study shows a high prevalence of hypertension among patients attending the HIV clinic at KBTH,associated with exposure to ART and increasing duration of this exposure. (bvsalud.org)
  • With regard to puerperal complications, mothers who underwent caesarean section had a higher prevalence of hypertension (71.1%) with an adjusted prevalence ratio of 3.90 (95% CI [2.00, 7.61]. (bvsalud.org)
Associated with preeclampsia1
  • The study found 18 independent loci (or genome locations) that were associated with preeclampsia/eclampsia and gestation hypertension. (preeclampsia.org)
Diabetes mellitus1
Seizures5
  • If left untreated, it may result in seizures at which point it is known as eclampsia. (wikipedia.org)
  • Eclampsia is unexplained generalized seizures in patients with preeclampsia. (merckmanuals.com)
  • Eclampsia is seizures that occur in women with preeclampsia and that have no other cause. (msdmanuals.com)
  • The woman's hands, fingers, neck, and/or feet may swell, and if preeclampsia is severe and not treated, she may have seizures (eclampsia) or organ damage. (msdmanuals.com)
  • The highest risk occurred among women taking antihypertensive medication, but even women not taking medication (but with a history of chronic hypertension) had triple the risk for stillbirth, neonatal death, respiratory support, low Apgar score, seizures, or cord blood acidemia, although the findings were limited by a nongeneralizable population and some underpowered measures. (medscape.com)
Hypertensive disorders of pregnancy2
Postpartum19
  • This is called postpartum preeclampsia. (medlineplus.gov)
  • Commonly, pre-eclampsia continues into the period after delivery, then known as postpartum pre-eclampsia. (wikipedia.org)
  • In a randomized trial of 220 women with preeclampsia or gestational hypertension, those who took daily postpartum BP readings and received clinician-guided advice for titrating antihypertensives had a 5 mm Hg lower average diastolic BP at 9 months, compared with those receiving usual care. (medscape.com)
  • Jamie Kitt, DPhil, from the University of Oxford, Oxford, England, presented these findings from the Physicians Optimized Postpartum Hypertension Treatment ( POP-HT ) clinical trial at the American Heart Association (AHA) 2023 Scientific Sessions. (medscape.com)
  • But that doesn't mean you should ditch exercise altogether, because there is plenty of evidence highlighting the benefits of exercise pre and postpartum. (lesmills.com)
  • Preeclampsia and postpartum preeclampsia are hypertensive disorders related to pregnancy. (healthline.com)
  • Postpartum preeclampsia happens soon after childbirth, whether or not you had high blood pressure during pregnancy. (healthline.com)
  • Postpartum preeclampsia is rare . (healthline.com)
  • Read on to learn more about identifying and treating postpartum preeclampsia. (healthline.com)
  • Postpartum preeclampsia is one such risk. (healthline.com)
  • Postpartum preeclampsia often develops within 48 hours of giving birth. (healthline.com)
  • Postpartum preeclampsia is a very series condition that can progress quickly. (healthline.com)
  • What causes postpartum preeclampsia? (healthline.com)
  • The causes of postpartum preeclampsia are unknown, but there are certain risk factors that may increase your risk. (healthline.com)
  • If you develop postpartum preeclampsia during your hospital stay, you most likely won't be discharged until it resolves. (healthline.com)
  • Your doctor will prescribe medication to treat postpartum preeclampsia. (healthline.com)
  • In addition to recovering from postpartum preeclampsia, you'll also be recovering from childbirth itself. (healthline.com)
  • Preeclampsia can be a concern during pregnancy and also after delivery, during the postpartum period. (lamaze.org)
  • The results revealed a high rate of teenage pregnancy, and arterial hypertension was the leading complication during the postpartum period experienced by women who had undergone caesarean section. (bvsalud.org)
Gestation hypertension1
Pregnant11
  • Sometimes, a pregnant woman with preeclampsia is admitted to the hospital. (medlineplus.gov)
  • Prevalences of prepregnancy obesity and gestational diabetes were higher among pregnant women hospitalized for COVID-19-related illness (e.g., worsening respiratory status) than among those admitted for pregnancy-related treatment or procedures (e.g., delivery) and found to have COVID-19. (cdc.gov)
  • Antenatal counseling emphasizing preventive measures, including use of masks, frequent hand washing, and social distancing, might help prevent COVID-19 among pregnant women, especially those with prepregnancy obesity and gestational diabetes. (cdc.gov)
  • Antenatal counseling emphasizing preventive measures (e.g., use of masks, frequent hand washing, and social distancing) might help prevent COVID-19 among pregnant women, § especially those with prepregnancy obesity and gestational diabetes, which might reduce adverse pregnancy outcomes. (cdc.gov)
  • With new genetic variants identified for preeclampsia and gestational hypertension, researchers created polygenic risk scores (PRS) that may better identify candidates for prophylactic low-dose aspirin among pregnant mothers. (medpagetoday.com)
  • For pregnant women, the vitamin can affect the regulation and function of proteins in the placenta, a problem associated with the early onset of pre-eclampsia. (growingyourbaby.com)
  • About 1 in 10 pregnant women develop hypertension in pregnancy (preeclampsia or gestational hypertension), and 1 in 3 such women go on to develop chronic hypertension within 10 years, "when they are usually still in their 30s or 40s," Leeson said. (medscape.com)
  • Building on these findings, the POP-HT trial enrolled 220 pregnant women seen at Oxford University Hospitals in the UK who were age 18 years or older, had either gestational hypertension or preeclampsia, and still required antihypertensives when they were being discharged from hospital after giving birth. (medscape.com)
  • Childbirth educators and other perinatal professionals have a responsibility to inform pregnant people about the signs and symptoms to watch for, in the case of preeclampsia, and to encourage them to reach out to a health care provider if they have any concerns. (lamaze.org)
  • Preeclampsia affects 3 to 7% of pregnant women. (merckmanuals.com)
  • Usually if severe hypertension occurs for the first time in pregnant women, doctors do tests to rule out other causes of hypertension. (msdmanuals.com)
Proteinuria2
Outcomes5
  • Pre-eclampsia increases the risk of undesirable as well as lethal outcomes for both the mother and the fetus including preterm labor. (wikipedia.org)
  • They then compared outcomes among 830 women with a history of chronic hypertension but blood pressure under 140/99 mm Hg before 20 weeks gestation with those of 476 women without chronic hypertension. (medscape.com)
  • In addition, preeclampsia, infants small for gestational age, and preterm birth before 37 and 34 weeks gestation were recorded as secondary outcomes. (medscape.com)
  • In relative terms, after adjustment for nulliparity and a history of preterm delivery, women with chronic hypertension but not taking medication were three times more likely to have a child with one of the primary outcomes than control group women (odds ratio [OR], 2.9). (medscape.com)
  • Therefore, the differences in outcomes may not be solely the result of the presence of chronic hypertension," the authors write. (medscape.com)
Preterm birth3
  • Gestational diabetes, preeclampsia , preterm birth, and birth of an infant small for gestational age are ranked as major risk factors for CVD. (medscape.com)
  • Compared with women without a history of hypertension, women taking antihypertensive medication also had significantly increased risks for preeclampsia , severe preeclampsia, preterm birth , and an infant small for gestational age after adjustments, but women with a history of hypertension not taking medications did not. (medscape.com)
  • No significant differences in preeclampsia, preterm birth, or infants small for gestational age occurred between women without a hypertension history and women with a history but not taking medication. (medscape.com)
10th percentile1
Small for3
Metabolic2
  • Background Deficiencies of enzymes in the folate cycle may lead to the generation of homocysteine, a toxic metabolic intermediate with pro-oxidant effect and ability to induce oxidant stress and lipid peroxidation as part of the pathophysiological process in gestational hypertension (GH) and pre-eclampsia (PE). (edu.ng)
  • Conclusion Pre-eclampsia and gestational hypertension are associated with marked homocysteine metabolic derangement and increased lipid peroxidation induced by oxidative stress and reduced MTHFR enzyme activity which may be the significant risk factors in the aetio-pathogenesis of GH and PE. (edu.ng)
Increases the risk1
  • Although many expectant mothers do not experience symptoms as a result, gestational diabetes increases the risk of pre-eclampsia, depression, and requiring a caesarean-section. (lesmills.com)
Prepregnancy2
  • Among established risk factors for preeclampsia, nulliparity carries the largest population-attributable risk (approximately one-third), and most affected individuals lack any overt prepregnancy risk factors other than nulliparity," according to Natarajan's group. (medpagetoday.com)
  • Objective To determine the efficacy of high dose folic acid supplementation for prevention of pre-eclampsia in women with at least one risk factor: pre-existing hypertension, prepregnancy diabetes (type 1 or 2), twin pregnancy, pre-eclampsia in a previous pregnancy, or body mass index ≥35. (bmj.com)
Occurs3
  • Untreated preeclampsia is present for a variable time, then can suddenly progress to eclampsia, which occurs in 1/200 patients with preeclampsia. (merckmanuals.com)
  • Eclampsia occurs in fewer than 1% of women with severe preeclampsia. (msdmanuals.com)
  • However, gestational hypertension often occurs late in pregnancy and does not require treatment with drugs. (msdmanuals.com)
Researchers2
  • The Preeclampsia Foundation offers research funding, study recruitment, and other patient engagement services to researchers. (preeclampsia.org)
  • The researchers first identified all singleton births from 2000 to 2014 at the University of Alabama at Birmingham in which the mother had a history of chronic hypertension. (medscape.com)
Practice Bulletin1
Prevention6
  • Recommendations for prevention include: aspirin in those at high risk, calcium supplementation in areas with low intake, and treatment of prior hypertension with medications. (wikipedia.org)
  • Third, include reproductive-aged women in ongoing hypertension prevention and intervention efforts. (cdc.gov)
  • Why is the search for pre-eclampsia prevention so elusive? (bmj.com)
  • Given its large public health burden, there is a need to identify modifiable factors that can be targeted for preeclampsia prevention. (ahajournals.org)
  • These data may be of value when designing interventions for prevention or treatment of pre-eclampsia. (bmj.com)
  • Table 8: Preeclampsia Risk Factors Based on Patient Medical History in Low-dose aspirin for the prevention of morbidity and mortality from preeclampsia: A systematic evidence review for the U.S. Preventive Services Task Force . (merckmanuals.com)
Mild1
  • If your baby is not fully developed and you have mild preeclampsia, the disease can often be managed at home until your baby has matured. (medlineplus.gov)
Women23
  • Preeclampsia is high blood pressure and signs of liver or kidney damage that occur in women after the 20th week of pregnancy. (medlineplus.gov)
  • Often, women who have preeclampsia do not feel sick. (medlineplus.gov)
  • Women who had low blood pressure at the start of their pregnancy, followed by a significant rise in blood pressure need to be watched closely for other signs of preeclampsia. (medlineplus.gov)
  • A population-based cohort study based on the Swedish Medical Birth Register 1992-98 and comprising 560 188 women aged 15-44 years with singleton pregnancies including 2,754 women with chronic hypertension. (nih.gov)
  • Methylene tetrahydrofolate Reductase Enzyme Level and Antioxidant Activity in Women with Gestational Hypertension and Pre-eclampsia in Lagos, Nigeria. (edu.ng)
  • Women who have had pre-eclampsia are at increased risk of high blood pressure, heart disease and stroke later in life. (wikipedia.org)
  • Additionally, some women may develop severe headache as a sign of pre-eclampsia. (wikipedia.org)
  • And fifth, create and share data products that guide various groups about hypertension and related risk factors among reproductive-aged women. (cdc.gov)
  • For example, women with chronic conditions, such as diabetes or obesity, have an increased risk of preeclampsia (2), a pregnancy-specific hypertensive disease that involves several body systems and typically starts after the 20th week of pregnancy (3). (cdc.gov)
  • The latest research compared the vitamin D levels of women with pre-eclampsia verses those without the condition. (growingyourbaby.com)
  • Of the women with pre-eclampsia, 54 percent were also found to have low vitamin D levels. (growingyourbaby.com)
  • Previously, the research group performed a pilot study, the Self-Management of Postnatal Antihypertensive Treatment ( SNAP-HT ) trial and the SNAP- extension trial , which compared a BP self-monitoring intervention with usual care in 91 women with gestational hypertension or preeclampsia requiring postnatal antihypertensive treatment. (medscape.com)
  • The study looked at hundreds of thousands of women with and without preeclampsia and gestational hypertension. (preeclampsia.org)
  • The 18 independent loci identified by this genome wide analysis study presents new avenues of research for identifying women who may be at genetic risk of developing preeclampsia. (preeclampsia.org)
  • Placental findings consistent with chronic hypertension were common among HIV-infected women who received HAART and among HIV-uninfected women (65% vs. 54%, p = 0.37), but less common among HIV-infected women not receiving HAART (28%, p = 0.003 vs. women on HAART). (plos.org)
  • In this study, we examined whether a Mediterranean‐style diet is protective for preeclampsia in a large cohort of racially and ethnically diverse, urban, low‐income women. (ahajournals.org)
  • Of 8507 women in the sample, 848 developed preeclampsia. (ahajournals.org)
  • Women who have chronic hypertension are more likely to have potentially serious problems during pregnancy. (msdmanuals.com)
  • Women with a history of chronic hypertension are three to five times more likely to have a poor pregnancy outcome than women without past hypertension, even if their blood pressure is normal before 20 weeks gestation, found a retrospective cohort study published April 6 in Obstetrics & Gynecology . (medscape.com)
  • The composite primary outcome occurred among 9.9% of women with a hypertension history but not taking antihypertensive drugs, in 14.6% of women who were taking antihypertensive drugs, and in 2.9% of women with no history of hypertension. (medscape.com)
  • The women taking antihypertension medications had five times the risk seen in women without a history of hypertension (OR, 5). (medscape.com)
  • The study's strengths include its population size, having data on blood pressure before and during pregnancy, and including women with confirmed prior diagnoses of chronic hypertension. (medscape.com)
  • Further, the low number of women with past hypertension who were not taking medications was underpowered (57%) to "detect a 50% reduction in the risk of the primary perinatal composite outcome in women without hypertension compared with the no medication group. (medscape.com)
ACOG1
  • Inclusion criteria were singleton pregnancies between 24+0 and 39+6 with either pre-eclampsia or gestational hypertension as defined by ACOG criteria. (bmj.com)
Pregnancies4
  • Pre-eclampsia affects 2-8% of pregnancies worldwide. (wikipedia.org)
  • It could then help determine what patients may benefit from aspirin therapy, even among patients with first-time pregnancies (which is itself a risk factor for preeclampsia). (preeclampsia.org)
  • We have demonstrated a significant reduction in platelet reactivity in patients with both pre-eclampsia and gestational hypertension compared to patients with uncomplicated pregnancies in the third trimester. (bmj.com)
  • Mothers with higher blood pressures were excluded, as were pregnancies with fetal anomalies and mothers with any major medical problems besides hypertension and diabetes. (medscape.com)
Placenta3
  • Preeclampsia usually resolves within 6 weeks after the baby is born and the placenta is delivered. (medlineplus.gov)
  • In those with pre-eclampsia, delivery of the baby and placenta is an effective treatment but full recovery can take days or weeks. (wikipedia.org)
  • Preeclampsia can cause the placenta to detach and/or the baby to be born too early, increasing the risk that the baby will have problems soon after birth. (msdmanuals.com)
Onset2
Risk5
  • The PRS predicted HDP risk among nulliparous female individuals independent of first-trimester risk factors, with the top 10% highest scorers confirmed to be at significantly higher risk of preeclampsia and gestational hypertension. (medpagetoday.com)
  • Further, those with pre-eclampsia may have a lower risk of breast cancer. (wikipedia.org)
  • A tool like this could help clinicians to assess a patient's overall risk for developing preeclampsia. (preeclampsia.org)
  • Moderate and severe preeclampsia is associated with a more than twofold increase in the risk for CVD. (medscape.com)
  • Gestational diabetes is associated with an increase in the risk for CVD by 68% and the risk of developing type 2 diabetes after pregnancy by 10-fold. (medscape.com)
Weeks of pregnancy1
  • Gestational age (GA) ranged from 10-42 weeks of pregnancy with mean GA calculated at 38 +3 weeks. (degruyter.com)
Dysfunction1
  • While historically both high blood pressure and protein in the urine were required to make the diagnosis, some definitions also include those with hypertension and any associated organ dysfunction. (wikipedia.org)
Usually fatal2
Diagnosis2
  • Edema (especially in the hands and face) was originally considered an important sign for a diagnosis of pre-eclampsia. (wikipedia.org)
  • Diagnosis depends on finding a coincidence of several pre-eclamptic features, the final proof being their regression within the days and weeks after delivery. (wikipedia.org)
Logistic regression1
  • We derived a Mediterranean‐style diet score from the food frequency questionnaire and performed logistic regression to examine the association of the Mediterranean‐style diet score with preeclampsia. (ahajournals.org)
Severe features2
  • A finding of preeclampsia can only be treated by delivery, timed according to gestational age and whether severe features of preeclampsia are present. (medpagetoday.com)
  • Tdap vaccine had a protective effect on pre-eclampsia with severe features, preterm labour, preterm delivery, and antenatal bleeding. (immune.org.nz)
Excess2
Prenatal2
  • Pre-eclampsia is routinely screened during prenatal care. (wikipedia.org)
  • evaluar el efecto de intervenciones en educación para la salud sobre el conocimiento y las prácticas de autocuidado de mujeres embarazadas ante los trastornos hipertensivos en el embarazo, en comparación con la atención estándar del control prenatal. (bvsalud.org)
Premature1
High6
Indicators1
  • Aim The aim of this study is to assess the reliability of plasma homocysteine (hcy) 5, 10 methylenetetrahydrofolate reductase (MTHFR) enzyme and oxidative stress parameters as indicators of aetio-pathogenesis and severity of gestational hypertension and pre-eclampsia. (edu.ng)
Occur2
  • While it is rare, preeclampsia also may occur in a woman after delivering her baby, most often within 48 hours. (medlineplus.gov)
  • Pregnancy complications, such as preeclampsia and eclampsia, are problems that occur only during pregnancy. (msdmanuals.com)
Mothers1
  • Anxiety can affect expectant mothers both pre and post-partem and can have a large impact on the mental health of the mother. (lesmills.com)