Germ cells and artificial artificial adult mammalian cells. Medical search. Frequent questions

5-Hydroxymethylcytosine is also associated with labile, unstable nucleosomes which are frequently repositioned during cell differentiation. (wikipedia.org)
Mammalian adult stem cells resemble the blastomeres of planktonic and benthic organisms with small eggs and may have evolved in mature organisms as an adaptation to the growth and maintenance of tissues via proliferation and the regulation of organ size via cell loss (e.g., terminal differentiation). (iospress.com)
We propose these results as a confirmation that apoptotic cells can control surrounding cells fate and as a reference database to explore novel apoptotic functions in animals, including those related to migration and differentiation. (biomedcentral.com)
Accumulating evidence in many metazoans suggest that apoptotic cells can emit caspase-dependent signals to their neighbours, modulating their fate (survival/death, differentiation or proliferation) or behaviour (migration) [ 12 , 13 ]. (biomedcentral.com)
Somatic cells are cells that have gone through the differentiation process and are not germ cells. (asu.edu)
The dynamics of RACK1 levels in isolated adult SC of mice, i.e., progressively high during differentiation and low compared to proliferating conditions, and RACK1 silencing indicated that RACK1 promotes both the formation of myotubes and the accretion of nascent myotubes. (sdbonline.org)
Epigenetic Regulation during Primordial Germ Cell Development and Differentiation. (ericmiskalab.org)
To establish protocols for the safe and efficient differentiation of healthy cells for therapies, we must develop a better understanding of the dynamic continuum of metabolic states that span pluripotency and differentiation, and how to influence them. (conditionmed.org)
In addition to supplying cellular energy, mitochondria are involved in other tasks, such as signaling , cellular differentiation , and cell death , as well as maintaining control of the cell cycle and cell growth . (wikipedia.org)
The term stem cell can be defined by two very important qualities: the cell has the ability to self-renew and, in a more general sense, the cell has not completed differentiation into its final state. (thefutureofthings.com)
This general definition includes a wide variety of cells with varying degrees of differentiation potential. (thefutureofthings.com)

Moreover, 5hmC is highly enriched in primordial germ cells, where it apparently plays a role in global DNA demethylation. (wikipedia.org)
Dynamics of male canine germ cell development [6] "Primordial germ cells (PGCs) are precursors of gametes that can generate new individuals throughout life in both males and females. (edu.au)
Previously, we have shown that the tail regression step during metamorphosis, characterized by a predictable polarized apoptotic wave, ensures elimination of most tail cells and controls primordial germ cells survival and migration. (biomedcentral.com)

The embryos of larger arthropods and deuterostomes with well-provisioned eggs or viviparity, on the other hand, exhibit regulative development, while their larval "set-aside" or adult stem cells function in the growth, maintenance, and regulation of organ size coupled to constrained proliferation and cell turnover. (iospress.com)
Patterns are ubiquitous in living systems and underlie the dynamic organization of cells, tissues, and embryos. (mpi-cbg.de)
Scientists have applied somatic cell nuclear transfer to clone human and mammalian embryos as a means to produce stem cells for laboratory and medical use. (asu.edu)

However, in 2009 it was found to be abundant in human and mouse brains, as well as in embryonic stem cells. (wikipedia.org)
Additionally, 5-Formylcytosine, an oxidation product of 5-Hydroxymethylcytosine and possible intermediate of an oxidative demethylation pathway was detected in DNA from embryonic stem cells, although no significant amounts of these putative demethylation intermediates could be detected in mouse tissue. (wikipedia.org)
Reduction in the 5-Hydroxymethylcytosine levels have been found associated with impaired self-renewal in embryonic stem cells. (wikipedia.org)
Mammalian embryonic stem cells would seem adapted to rapid proliferation, functioning in part to enclose yolk or to acquire access to maternal resources. (iospress.com)
The cellular products of embryonic stem cells routinely come under global influences and give rise to the cells of germ layers and organ rudiments. (iospress.com)
Strategies for regenerative therapies in adult mammals, therefore, might be based on stimulating growth of adult stem cells or their surrogates in specific tissues rather than on introducing embryonic stem cells into adults. (iospress.com)
In the future, embryonic stem cells may be able to restore sight to millions of people. (thefutureofthings.com)
These adult stem cells are considered multipotent, having the ability to differentiate into different cell types, albeit with a more limited repertoire than embryonic stem cells. (thefutureofthings.com)
In rodents, and even in some preliminary trials in humans, human embryonic stem cells have been shown to bridge gaps in spinal cord injuries , allowing restoration of motor functions. (thefutureofthings.com)

The fertilized oocyte is totipotent, with resultant blastomeres capable of generating all three primary germ layers, ectoderm, mesoderm, and endoderm, in addition to the extra embryonic tissues. (conditionmed.org)
The ICM continues to differentiate into three germ layers-ectoderm, mesoderm and endoderm, each of which follows a specific developmental destiny that takes them along an ever-specifying path at which end the daughter cells will make up the different organs of the human body. (thefutureofthings.com)

Maybe this way of keeping sibling cells connected in a colony or cluster is the beginning of how multicellular evolution occurred, and maybe germ cells are a reflection of that. (sciencedaily.com)
Early life forms on Earth, starting at least 3.7 billion years ago,[12] were single-celled organisms (an organism that consists of a single cell, unlike a multicellular organism that consists of multiple cells). (stevechase.org)
Some cells in some multicellular organisms lack mitochondria (for example, mature mammalian red blood cells ). (wikipedia.org)

The early mammalian embryo consists of the extra-embryonic cell layers-the trophoblast and a body of cells called the inner cell mass (ICM), which eventually become the embryo proper. (thefutureofthings.com)

This was demonstrated in vitro and in live human and mouse cells by scientists working in the labs of Anjana Rao and David R. Liu. (wikipedia.org)
Assisted reproductive techniques for canines: preservation of genetic material in domestic dogs [3] "Assisted reproductive techniques (ARTs), such as artificial insemination, in vitro fertilization, and cryopreservation of gametes/zygotes, have been developed to improve breeding and reproduction of livestock and for the treatment of human infertility. (edu.au)
2000. Results of the L5178Y mouse lymphoma assay and the Balb/3T3 cell in vitro transformation assay for eight phthalate esters. (cdc.gov)
A defined synthetic mixture of amino acids, salts, carbohydrates, vitamins and serum was shown to support cells in vitro[ 3 ], thus unifying a major variable in cell culturing experiments and providing a possibility for rapid development of this novel method. (intechopen.com)
Practically, cycle regulation, chromosome stability and epigenetic F9 cells allow for the efficient metabolic labelling of the modification, in both mouse and human oocytes SILAC reference in vitro, overcoming the difficulty of directly labelling oocytes in vivo. (gotomydoctor.com)
We discuss what is known about the distinct metabolic states captured in vitro by the 2-cell-like, naïve, blastocyst-like, formative, and primed states of pluripotency. (conditionmed.org)
2019). Akin to the dynamic nutrient requirements of the developing embryo, discrete in vitro cell states have distinct metabolic profiles (Zhou et al. (conditionmed.org)
It is only through understanding embryonic metabolism and development that we can derive and maintain different in vitro stem cell states for disease modeling and therapies. (conditionmed.org)
Using biologically relevant elastic substrates to study cell function in vitro has proven beneficial, as the in vivo microenvironment usually is much softer than rigid plastic dishes. (5dok.org)

Scientists have observed ring canals in male and female germ cells across all types of species, from simpler organisms like sponges and fruit flies to more complex animals like mice and humans. (sciencedaily.com)
Apoptotic-induced proliferation was reported in several organisms, such as in the cnidarian Hydra , where apoptosis promotes proliferation of adjacent cells through emission of Wnt3 signalling in a caspase-dependant manner during head regeneration [ 14 ]. (biomedcentral.com)
Such organisms (Prokaryotes, Protozoans, algae) multiply by fission into daughter cells. (stevechase.org)

Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues. (mpi-cbg.de)
In order to address the limits associated with current therapies, many research groups have investigated various regenerative medicine strategies utilizing different stem cell sources to engineer artificial salivary tissues that can mitigate the effects of xerostomia and hyposalivation. (biomedcentral.com)
In addition to their ability to supply cells at the turnover rate of their respective tissues, they can be stimulated to repair injured tissue caused by liver damage, skin abrasions and blood loss. (thefutureofthings.com)
The ability of our body to regenerate some of its tissues is largely owed to the reserves of adult stem cells. (thefutureofthings.com)

Research from recent decades has highlighted how microbiota influences the cellular and molecular responses of the host somatic cells. (mpg.de)
Somatic cell nuclear transfer (SCNT) is a technology applied in cloning, stem cell research and regenerative medicine. (asu.edu)

However, whether these microbiota-epigenetic interactions can extend to germ cells or are even transmitted across generations remains an open question. (mpg.de)
Nevertheless, it remains largely unexplored how gut microbiota and their metabolic products influence mammalian epigenetic mechanisms in early-life programming," says Ayele Argaw Denboba. (mpg.de)
Beyond a better mechanistic understanding of the associations between microbiota composition and epigenetic modifications for regulating germ cells, the research enriches the field of reproductive biology. (mpg.de)

Going forward, the researchers aim to identify the mechanisms that drive germ cells to remain connected. (sciencedaily.com)
While much is known about biochemical signaling, many of the mechanisms that drive cell outcome in response to biophysical influences remain to be uncovered. (5dok.org)

Their larval and adult cells have narrow potencies, sometimes coupled to virtually unlimited … proliferation, and function in the growth, maintenance and regulation of body size. (iospress.com)
Apoptosis is also implicated in homoeostasis by fine-tuning the balance between cell death and proliferation like in gonad size control in rodents [ 11 ]. (biomedcentral.com)
This work evaluated the effect of ex situ management on neurogenesis (cell proliferation in the dorsal and medial ventricular zones, neuronal integration in the dorsomedial and medial cortices), ovary cell proliferation, body size (mass and length) and self-righting ability. (frontiersin.org)
Although a "default state" is a theoretical construct and a limit case that does not need to be instantiated, conditions that closely resemble unrestrained cell proliferation are readily obtained experimentally. (bsahely.com)
Eph/ephrin signaling is a cell-to-cell communication pathway, which regulates cell migration and proliferation. (5dok.org)

We explore the recently described metabolic surge event that occurs as pluripotency is lost and stem cells commit to differentiate. (conditionmed.org)
Finally, we explore the most recent understanding of germ layer-specific metabolic remodeling. (conditionmed.org)
The developing embryo, from which pluripotent stem cells originate, undergoes a series of dynamic metabolic transitions synchronized to its molecular development. (conditionmed.org)

But what is not getting such wide reporting is the use of pluripotent stem cells (as well as many other types of cells and genetic engineering techniques) for reproductive purposes . (lifeissues.net)
Reproduction (2014) 148 55-72 (Thus, ageing of oocytes may The 'maternal age effect' in reproduction, characterized be viewed as a life-long maintenance of cellular by a negative relationship between maternal age and homeostasis in the same cell, unlike ageing of the male reproductive success, is a poorly understood phenom- germline. (gotomydoctor.com)
However, over the last 10years, with advancements in artificial reproductive tech-niques and the successful delivery of healthy children from men with Klinefelter syndrome, the involvement of Klinefelter syndrome is the most common numerical urologists in the care of patients with Klinefelter syn- chromosomal aberration among men, with an estimated drome is increasingly important. (health-abstracts.com)

The use of various types of stem cells for research purposes to make disease "models" in the lab for regenerative medicine and for "therapies" to cure sick patients for diseases is constantly in the news. (lifeissues.net)
11] In contrast, many species can be considered potentially immortal: for example, bacteria fission to produce daughter cells, strawberry plants grow runners to produce clones of themselves, and animals in the genus Hydra have a regenerative ability by which they avoid dying of old age. (stevechase.org)

They tagged several ring canal proteins in fruit flies with florescent molecules and, using a microscope, observed what those proteins did over time in the germ cells of both males and females. (sciencedaily.com)
Furthermore, GSOs protected cells against GLU-induced apoptosis by reducing the expression of the mitochondrial apoptosis-associated Bcl-2 family effector proteins and protected cells from GLU-induced oxidative damage by increasing the nuclear translocation of Nrf2 and HO-1 expression. (sdbonline.org)
P-granules are large ribonucleoprotein complexes found specifically in the germ line cytoplasm, and PGL-1 and PGL-3 proteins are representative constituents of P-granules Kawasaki et al. (glassven.com)

For example, in female fruit flies, ring canals are required to grow a functional oocyte, a developing egg cell," said Lynn Cooley, the C.N.H. Long Professor of Genetics at Yale School of Medicine and senior author of the new study. (sciencedaily.com)
4 ] in 1951 cell culturing has become one of the most widely used methods with exceptional contribution to the advances in almost all fields of contemporary biology - cell biology, genetics, cell biochemistry, physiology etc. (intechopen.com)

Apoptosis is a caspase regulated cell death present in all metazoans defined by a conserved set of morphological features. (biomedcentral.com)
A well-described function of apoptosis is the removal of excessive cells during development and homeostasis. (biomedcentral.com)
In contrast to the apoptotic function of cell elimination, this new role of apoptosis is not well understood but seems caspase-dependent. (biomedcentral.com)
To deepen our understanding of apoptotic functions, it is necessary to work on a biological model with a predictable apoptosis pattern affecting cell fate and/or behaviour. (biomedcentral.com)
While the function of cell elimination by apoptosis is highly documented, apoptosis seems to have a broader morphogenetic function that goes beyond cells elimination. (biomedcentral.com)
Evaluating the capacity of caspases to affect gene expression and influence fate and/or behaviour of cells adjacent to apoptosis is the first fundamental step to better characterise this new function in animals. (biomedcentral.com)
Programmed ageing should not be confused with programmed cell death (apoptosis). (stevechase.org)

The role of DNA methylation on sexual determination and development in zebrafish germ cells. (exeter.ac.uk)

The Hsieh laboratory is a neural stem cell biology laboratory that focuses on 4 major areas: (1) epilepsy-in-a-dish, (2) 3D cerebral organoids, (3) patient recruitment, and (4) mechanisms of adult neurogenesis. (utsa.edu)

Up to the 2-cell embryo, blastomeres remain totipotent (Garner and McLaren, 1974). (conditionmed.org)

There are very primitive creatures that, when they divide, make colonies that are attached with persistent cellular bridges, much like what we see with germ cells," said Cooley. (sciencedaily.com)
Cellular immunology, T cell immunity, autoimmune diseases: The immune system plays a fundamental role in the defense against microbial pathogens. (utsa.edu)
Current knowledge of cellular behavior is mainly acquired by studies concerning homogenous populations of cells cultured as monolayers. (intechopen.com)
Multiple research groups have developed artificial mitochondrial transfer/transplantation (AMT/T) methods that transfer healthy mitochondria into damaged cells and recover cellular function. (biomedcentral.com)
[20] This finding has led to general acceptance of the endosymbiotic hypothesis - that free-living prokaryotic ancestors of modern mitochondria permanently fused with eukaryotic cells in the distant past, evolving such that modern animals, plants, fungi, and other eukaryotes are able to respire to generate cellular energy . (wikipedia.org)

When caspase activity was impaired, genes known to be involved in metamorphosis were downregulated along with other implicated in cell migration and survival molecular pathways. (biomedcentral.com)
Unlike the male germline, the bulk of The synthesis of the aforementioned molecular oocytes do not have a gonial stem cell population. (gotomydoctor.com)

This simplified approach towards understanding the essence of the mechanisms, underlying the processes determining life and death of a cell has undoubtedly provided scientists with enormous amount of knowledge. (intechopen.com)
While regarded by many top scientists as the Holy Grail of medicine, others consider embryonic stem-cell research sacrilegious. (thefutureofthings.com)
A number of large biotech companies and scientists are looking toward stem cells as the basis for a therapeutic solution to cure such illnesses as blindness, diabetes and spinal cord injuries. (thefutureofthings.com)

Here, removal of intact α 6 protein from cerebellar granule cells allowed perturbations in other subunit levels to be studied. (jneurosci.org)
In α 6 −/− granule cells, the δ subunit was selectively degraded as seen by immunoprecipitation, immunocytochemistry, and immunoblot analysis with δ subunit-specific antibodies. (jneurosci.org)
The δ subunit mRNA was present at wild-type levels in the mutant granule cells, indicating a post-translational loss of the δ subunit. (jneurosci.org)
For example, cerebellar granule cells express six subunit genes abundantly (α 1 , α 6 , β 2 , β 3 , γ 2 , and δ), and so they probably have several distinct GABA A receptor subtypes of unknown subunit stoichiometry. (jneurosci.org)
Inhibition generated by granule cells, the most common GABAergic cell type in the olfactory bulb, plays a critical role in shaping the output of the olfactory bulb. (jneurosci.org)
Using two-photon guided minimal stimulation in acute rat brain slices, we found that distal and proximal excitatory synapses onto granule cells are functionally distinct. (jneurosci.org)
Most excitatory synapses we examined onto granule cells activated both NMDARs and AMPA receptors, whereas a subpopulation appeared to be NMDAR silent. (jneurosci.org)
The convergence of two types of excitatory inputs onto GABAergic granule cells provides a novel mechanism for regulating the degree of interglomerular processing of sensory input in the olfactory bulb through piriform cortex/olfactory bulb synaptic interactions. (jneurosci.org)
Although the dendritic arborization of granule cells is relatively small (50-200 μm) ( Shepherd and Greer, 1998 ), a single granule cell may receive synaptic inputs from mitral cells several millimeters away ( Shepherd and Greer, 1998 ), providing a theoretical basis for massive synaptic divergence. (jneurosci.org)
In vivo recordings, however, suggest that unlike glutamatergic mitral cells, inhibitory granule cells are only weakly activated after sensory stimulation ( Cang and Isaacson, 2003 ). (jneurosci.org)
These findings raise the possibility that the pattern of interneuronal activation, and thus lateral inhibition onto principal cells, is not regulated predominately by dendrodendritic synaptic inputs but instead may reflect the temporal coincidence of several types of synaptic inputs to granule cells. (jneurosci.org)
Tetanic stimulation of axons in the granule cell layer (GCL) not only activates granule cells but also relieves the Mg blockade of NMDA receptors at distal dendrodendritic synapses ( Halabisky and Strowbridge, 2003 ). (jneurosci.org)
These results suggest that the proximal excitatory inputs to granule cells may play an important role in gating recurrent and lateral dendrodendritic inhibition (DDI) in the olfactory bulb. (jneurosci.org)
Shipley and Adamek, 1984 ) innervate granule cells at proximal synapses. (jneurosci.org)
Two classes of spontaneous EPSCs in granule cells. (jneurosci.org)
A , Schematic diagram of excitatory synapses onto granule cells. (jneurosci.org)

HN - 2008 BX - Von Ebner's Glands MH - Cumulus Cells UI - D054885 MN - A05.360.319.114.630.535.200.500 MN - A06.407.312.497.535.300.500 MN - A11.436.300.500 MS - The granulosa cells of the cumulus oophorus which surround the OVUM in the GRAAFIAN FOLLICLE. (bvsalud.org)
HN - 2008 BX - Granulosa Cells, Cumulus MH - Coronary Sinus UI - D054326 MN - A07.231.908.194.500 MS - A short vein that collects about two thirds of the venous blood from the MYOCARDIUM and drains into the RIGHT ATRIUM. (bvsalud.org)

So when I was recently contacted by an earnest and amiable member of a local school board who was concerned about the questionable manner in which the issue of "stem cell" research - both human embryonic and adult - was presented to the high school students in his district in a currently-used science textbook, I agreed to evaluate that section in the text for him. (lifeissues.net)
My edited analysis of the section on "stem cell research" in this science textbook is copied below. (lifeissues.net)
In my opinion there is no question but that the scientific information on stem cell research included in this science text book being used in Illinois schools incorporates some inaccurate scientific facts, and seems to be very partial to the use of human embryonic "stem cell" research. (lifeissues.net)
Recent advances in the field of stem-cell research are giving hope to millions. (thefutureofthings.com)
A particular field encouraged by the foundation is stem-cell research, with the great hope that it will result in the ability to get cells to differentiate into neurons and support cells to bridge the gap of a spinal cord injury. (thefutureofthings.com)

This quantitative study explores the acceptability of Online Learning Action Cell (LAC) practice as a school-based professional development strategy for Tagumpay National High School (TNHS) teachers. (philarchive.org)
Mystification may have been introduced historically with the concepts of determinate and regulative development, but, hopefully, the muddle can be resolved by tracing the evolution of stem cells in Metazoa. (iospress.com)
In a new study, researchers uncover how it is that germ cells in fruit flies form these ring canals, a finding that they say will provide new insights into a widely shared feature of development and into diseases in which cell division is disrupted. (sciencedaily.com)
And while their purpose is not fully understood, there is evidence that ring canals are important for cell development, the researchers say. (sciencedaily.com)
In addition to being an important step toward understanding the function and formation of ring canals, the researchers say, the new discovery may also yield insight into incomplete cell division that occurs in typical development across a variety of species and into diseases where incomplete cell division is implicated, such as colorectal cancer, Hodgkin's lymphoma, and some immunodeficiency syndromes. (sciencedaily.com)
This study examined the hypercapnic ventilatory response of rats, hamsters, and ground squirrels raised in burrow-like hypercapnia (â ¼3 % CO2) through development (embryonic day 16-18 to postnatal day 30) to determine if chronic hypercapnia exerts any effect on the developing and adult semi-fossorial response. (bvsalud.org)
The general underlying strategy behind the development of tissue engineered organ substitutes is the utilization of a combination of cells, biomaterials, and biochemical cues intended to recreate the natural organ environment. (biomedcentral.com)
Here, we consider the metabolism of the early embryo through development, and look at the nutrient milieu within the developing stem cell niche. (conditionmed.org)
2020). This places metabolism at the forefront of development and cell state decisions. (conditionmed.org)
This signaling pathway is a highly conserved cell-to-cell communication system that regulates cell fate in development and disease. (5dok.org)
We propose an opportunity to target the cancer cell/microenvironment interface instead of the Notch pathway itself in the development of cancer therapies. (5dok.org)

RACK1 was expressed transiently in the skeletal muscle of post-natal mice, being abundant in the early phase of muscle growth and almost disappearing in adult mature fibers. (sdbonline.org)
Do-Hyun Kim, PhD, a postdoctoral research associate and first author on the study, performed the experiments in germ-free mice lacking intestinal bacteria. (sciencedaily.com)

1] In a broader sense, ageing can refer to single cells within an organism which have ceased dividing, or to the population of a species. (stevechase.org)
The number of mitochondria in a cell can vary widely by organism , tissue , and cell type. (wikipedia.org)
At the top of the list comes the zygote-a fertilized egg, which of course has the ability to divide and differentiate into all cell types in the body and create a new organism. (thefutureofthings.com)
The first three divisions of the zygote give birth to eight totipotent cells, each of which also has the ability to become an entire organism. (thefutureofthings.com)

Collectively, this study provides the first evidence that transient levels of the evolutionarily conserved factor RACK1 are critical for adult SC activation and proper skeletal muscle regeneration, favoring the efficient progression of SC from a committed to a fully differentiated state. (sdbonline.org)

This contradicts all research conducted on mammalian DNA composition conducted before and since, including the Heintz and Rao papers, and another group was unable to reproduce Yura's result. (wikipedia.org)

We used conjugated polymers to develop a novel neural stem cell culture substrate with anchored growth factors to promote cell self-renewal. (5dok.org)

As the embryonic cells divide and the daughter cells differentiate, they become increasingly specific. (thefutureofthings.com)

This laboratory pursues several lines of investigation to understand how T cells contribute to autoimmune diseases and protection from infection, and how to modulate T cell immunity for therapeutic purposes in humans. (utsa.edu)
Republican National Committee Normal human cells however die after about 50 cell divisions in laboratory culture (the Hayflick Limit, discovered by Leonard Hayflick in 1961). (stevechase.org)

Although sturgeons are dioecious, it is difficult to distinguish females and males using morphological characteristics in larval, juvenile or even adult stages. (researchsquare.com)

Shettles, a physician, who specialized in obstetrics and gynecology, found a difference in the size and shape of male sperm cells that he correlated with the different sex chromosomes they carry. (asu.edu)

check the tag ADOLESCENCE HN - 2008 BX - Nutrition in Adolescence FX - Adolescent Nutrition Physiology MH - Peritoneal Stomata UI - D054048 MN - A01.047.025.600.700 MN - A10.810 MS - Natural openings in the subdiaphragmatic lymphatic plexus in the PERITONEUM, delimited by adjacent mesothelial cells. (bvsalud.org)

Recent studies have shown an unexpected signalling property of apoptotic cells, affecting cell fate and/or behaviour of neighbouring cells. (biomedcentral.com)
Student projects in my lab will revolve around cell-fate decisions in Spermatogonial Stem Cells (SSC). (utsa.edu)
SSCs are adult-tissue stem cells in the mammalian testis that balance self renewing and differentiating fate decisions to give rise to and sustain the entire spermatogenic lineage. (utsa.edu)
The cells of the ICM are no longer omnipotent, because they no longer share the fate of the trophoblast, and they have committed themselves to an embryonic fate with the ability to become any cell in the body (but not the trophoblast). (thefutureofthings.com)

Skeletal muscle growth and regeneration involves the activity of resident adult stem cells, namely satellite cells (SC). (sdbonline.org)
This article is intended to provide a review of the most current approaches to utilizing stem cells and bioengineering principles for the purpose of salivary tissue regeneration. (biomedcentral.com)

Finally, apoptotic cells modulate death or survival balance, as was observed in the Drosophila imaginal disc, by producing the Tie ligand Pvf1, that induces death resistance of neighbouring cells [ 17 ]. (biomedcentral.com)

Computed tomography (CT) is widely used to evaluate morphological features and diagnose head disorders in adult dogs. (edu.au)

Since the establishment of the first cell line by Gey et al. (intechopen.com)
Among these is the isolation of the first line of murine stem cells [ 5 , 6 ] in 1981, followed by establishment of the first human embryonic stem cell lines by Thompson [ 7 ]. (intechopen.com)
Even within humans and other mortal species, there are cells with the potential for immortality: cancer cells which have lost the ability to die when maintained in a cell culture such as the HeLa cell line,[17] and specific stem cells such as germ cells (producing ova and spermatozoa). (stevechase.org)

An improved ontological representation of dendritic cells as a paradigm for all cell types. (philarchive.org)
dendritic cell ontology (DC-CL). (philarchive.org)

Likewise, strategies for the containment of cancer might be based on promoting normal pathways of cell loss, the basal mode for handling excess cells. (iospress.com)

As for the virus of the mad cow or the AIDS, reports(connections) state (here) of " germs escaped " from laboratories. (scienceblogs.com)
Avant-garde approaches to stem-cell therapy may be the first stepping-stones to a bright new future of stem-cell medicine and are emerging in leading laboratories worldwide. (thefutureofthings.com)

Currently, the CL employs multiple is_a relations, defining cell types in terms of histological, functional, and lineage properties, and the majority of definitions are written with sufficient generality to hold across multiple species. (philarchive.org)
But across many species, germ cells, those that become eggs or sperm, don't fully separate. (sciencedaily.com)
Cell damage was assessed using MTT assays, and the lactate dehydrogenase (LDH) release rate and flow cytometry were used to detect the accumulation of reactive oxygen species (ROS) and mitochondrial membrane potential respectively. (sdbonline.org)

Voronina E, Seydoux G, Sassone-Corsi P, Nagamori I. RNA granules in regulating mRNA pristiq manufacturer discount stability Knockdown of decapping factors to germ granules. (josephineknight.com)

On the cover: Human induced pluripotent stem cell-derived neuroepithelial-like stem cells stained for actin (green) and DNA (blue). (5dok.org)

The highest levels are found in neuronal cells of the central nervous system. (wikipedia.org)

In particular, scientific developments in areas such as iPS cells open new possibilities of research and, at mid term, of therapeutic applications, but they also bring new ethical challenges and problems requiring further reflection and debate. (lifeissues.net)
International bi-monthly journal of cell signaling, tissue protection, and translational research. (conditionmed.org)
Stem cells are at the forefront of medical research and incite some of the most controversial ethical and religious debates worldwide. (thefutureofthings.com)

The blastocyst comprises the inner cell mass (ICM), which gives rise to the three primary germ layers and consequently the fetus, and the trophectoderm (TE), which gives rise to the extraembryonic and placental tissue. (conditionmed.org)

35 It is true that I am excluding here as elsewhere red blood cells which have no nucleus once released into the blood, and sperm or eggs with only 1,500,000,000 bases in them. (globalchange.com)

Exercise bout improves the activity of immune cells against harmful pathogenic substances in parallel with an enhanced recirculation of antibodies, immune cells as well as anti-inflammatory signals. (yogaoffreedom.guru)
A night of good sleep helps in growth, repair, and rejuvenation of your body According to a new study , s leep improves the potential ability of some of the body's immune cells such as T cell to attach to their targets. (yogaoffreedom.guru)
Stomach distention after chitin ingestion activates an innate immune response that triggers stomach cells to ramp up production of enzymes, known as chitinases, that break down chitin. (sciencedaily.com)

The Acceptability of Online Learning Action Cell Session Practice to Tagumpay National High School Teachers. (philarchive.org)
Andrology, sexual dysfunction and infertility Figure 1 The classic descriptions of men with Klinefelter syndrome are based on the most severe cases of phenotypic abnormalities Most teenagers and young adults seen in our practice have typical body proportions, arm span and penile length as their peers. (health-abstracts.com)
Are stem cells to become the future silver bullet of medical practice? (thefutureofthings.com)
Adult stem cells can be used to replace damaged heart-muscle cells and are used in practice today . (thefutureofthings.com)
The most common application of adult stem cells is probably the restoration of blood cells for patients with leukemia, and there are many more applications currently in practice. (thefutureofthings.com)

Here we have investigated biophysical regulation of cell function. (5dok.org)

Adult stem cells can be used to accelerate bone or tendon healing , and they can induce cartilage progenitor cells to produce a better matrix and repair cartilage damage . (thefutureofthings.com)

Anatomy69

Organisms22

Diseases15

Chemicals and Drugs53

Analytical, Diagnostic and Therapeutic Techniques and Equipment26

Psychiatry and Psychology1

Phenomena and Processes71

Disciplines and Occupations1

Information Science4

Differentiation11

Primordial3

Embryos3

Embryonic stem9

Mesoderm2

Multicellular3

Extra embryonic1

Vitro9

Organisms3

Tissues4

Somatic2

Epigenetic3

Mechanisms that drive2

Proliferation5

Metabolic3

Reproductive3

Regenerative2

Proteins3

Genetics2

Apoptosis7

Methylation1

Biology1

Blastomeres1

Cellular5

Molecular2

Scientists3

Granule cells16

Granulosa cells2

Stem cell res5

Development11

Mice2

Organism4

Efficient1

Composition1

Neural stem1

Differentiate1

Laboratory2

Larval1

Chromosomes1

Physiology1

Fate4

Regeneration2

Modulate1

Morphological features1

Line3

Dendritic2

Pathways1

Laboratories2

Species3

MRNA1

Human1

Neuronal1

Research3

Layers1

Eggs1

Immune3

Practice5

Regulation1

Induce1