• Daily gentamicin using ideal body weight demonstrates lower risk of postpartum endometritis and increased chance of successful outcome compared with traditional 8-hour dosing for the treatment of intrapartum chorioamnionitis. (qxmd.com)
  • In crude analysis, compared to traditional dosing, IDW daily dosing was associated with a lower risk of postpartum endometritis (RR 0.42, 95% CI 0.16-1.10, p = .032). (qxmd.com)
  • Daily dosing of gentamicin using ideal body weight is associated with a lower risk of postpartum endometritis and high chance of a successful outcome in the treatment of intrapartum chorioamnionitis compared with traditional 8-hour dosing in our ethnically diverse, urban population and thus may be considered a superior option to every 8 hours dosing regimens. (qxmd.com)
  • Postpartum endometritis is uterine infection, typically caused by bacteria ascending from the lower genital or gastrointestinal tract. (msdmanuals.com)
  • Endometritis may develop after chorioamnionitis during labor or postpartum. (msdmanuals.com)
  • Typically, the first symptoms of postpartum endometritis are lower abdominal pain and uterine tenderness, followed by fever-most commonly within the first 24 to 72 hours postpartum. (msdmanuals.com)
  • After the first 24 hours, postpartum endometritis is presumed present if no other cause is apparent in patients with temperature ≥ 38 ° C on 2 successive days. (msdmanuals.com)
  • Chlamydia has been associated with late-onset postpartum endometritis. (medscape.com)
  • The incidence of postpartum endometritis in the United States varies depending on the route of delivery and the patient population. (medscape.com)
  • Ascending infection of the uterus with Gram-negative bacteria is responsible for postpartum endometritis in cattle and buffalo and can adversely affect fertility. (ac.ir)
  • In the present study, 30 virgin Swiss Albino mice (5-8 weeks old) were used to evaluate the pathogenic potential of Escherichia coli, isolated from the normally calved postpartum buffalo to induce endometritis. (ac.ir)
  • Relationship between intra-uterine bacterial contamination, endotoxin levels and the development of endometritis in postpartum cows with dystocia or retained placenta. (ac.ir)
  • Intraamniotic infection can lead to complications for the mother as well, such as postpartum hemorrhage , endometritis , and sepsis. (medscape.com)
  • postpartum uterine flaccidity and accumulation of lochia: inappropriate management of placenta retention, uterine prolapse, vaginal and cervical inflammation, improper treatment, inadequate disinfection and bacterial infection of the uterus, causing endometritis. (ballyabio.com)
  • Chronic endometritis is more common after menopause. (wikipedia.org)
  • Chronic endometritis is characterized by the presence of plasma cells in the stroma. (wikipedia.org)
  • Patients with chronic endometritis may have an underlying cancer of the cervix or endometrium (although infectious cause is more common). (wikipedia.org)
  • Women with chronic endometritis are also at a higher risk of pregnancy loss and treatment for this improves future pregnancy outcomes. (wikipedia.org)
  • In human medicine, pyometra (also a veterinary condition of significance) is regarded as a form of chronic endometritis seen in elderly women causing stenosis of the cervical os and accumulation of discharges and infection. (wikipedia.org)
  • Symptom in chronic endometritis is blood stained discharge but in pyometra the patient complaints of lower abdominal pain. (wikipedia.org)
  • Chronic endometritis in the obstetric population is usually associated with retained products of conception after delivery or elective abortion. (medscape.com)
  • In the nonobstetric population, chronic endometritis has been seen with infections (eg, chlamydia, tuberculosis, bacterial vaginosis) and the presence of an intrauterine device. (medscape.com)
  • Gynecologic Infections , including endometritis and pelvic cellulitis caused by Escherichia coli , Klebsiella pneumoniae 1 , Enterobacter species 1 including E. cloacae 1 , and Proteus mirabilis 1 . (pfizermedicalinformation.com)
  • For the treatment of uterine infections (endometritis, metritis and pyometra) in mares, when caused by susceptible organisms including Escherichia coli, Pseudomonas sp and Klebsiella sp. (bodaxvet.com)
  • Rates of endometritis are about 2% following vaginal delivery, 10% following scheduled C-section, and 30% with rupture of membranes before C-section if preventive antibiotics are not used. (wikipedia.org)
  • women undergoing cesarian deliveries are also more likely to have endometritis than those undergoing vaginal delivery . (medscape.com)
  • The combination of clindamycin and gentamicin administered intravenously every 8 hours has been considered the criterion standard treatment. (medscape.com)
  • There is not enough evidence for the use of prophylactic antibiotics to prevent endometritis after manual removal of placental in vaginal birth. (wikipedia.org)
  • A Cochrane database systematic review concluded that the use of vaginal chlorhexidine douching during labor does not prevent endometritis. (medscape.com)
  • Our primary outcomes were resolution of infection following delivery without the development of maternal endometritis and/or neonatal sepsis. (qxmd.com)
  • Only three studies have examined daily gentamicin for the treatment of intrapartum chorioamnionitis and thus is insufficiently investigated. (qxmd.com)
  • This study seeks to determine whether daily dosing of gentamicin using ideal body weight for the treatment of intrapartum chorioamnionitis is more or equivalently efficacious when compared to traditional 8-hour dosing regimens. (qxmd.com)
  • We conducted a retrospective cohort study and reviewed charts on all women receiving treatment for intrapartum chorioamnionitis, which included intravenous gentamicin daily dosing calculated using 5 mg/kg ideal body weight or receiving traditional every 8 hours dosing of gentamicin at two large academic centers. (qxmd.com)
  • There was no statistical difference in incidence of endometritis ( P = 0.34), wound infection ( P = 0.44), or other febrile morbidity ( P = 0.5). (who.int)
  • [ 23 ] Preoperative use of povidone-iodine vaginal preparation prior to cesarean delivery appears to decrease the incidence of postcesarean endometritis but does not seem to decrease the overall risk of postoperative fever or wound infection. (medscape.com)
  • The Centers for Disease Control and Prevention (CDC) 2015 sexually transmitted diseases treatment guideline defines PID as any combination of endometritis, salpingitis, tubo-ovarian abscess, and pelvic peritonitis. (medscape.com)
  • Antibiotic coverage for Bacteroides, group B and A streptococci, Enterobacteriaceae organisms, and Chlamydia trachomatis in endometritis is suggested. (medscape.com)
  • Although universal agreement does not exist regarding the antibiotic regimen of choice, most studies have evaluated intravenous ampicillin dosed at 2 g every 6 hours plus gentamicin dosed every 8 hours. (qxmd.com)
  • Recommended antibiotic regimens for treatment of intraamniotic infection are ampicillin and gentamicin , cefazolin and gentamicin, or clindamycin or vancomycin and gentamicin. (medscape.com)
  • The diagnosis of endometritis is usually based on clinical findings, such as fever and lower abdominal pain (see Clinical Presentation). (medscape.com)
  • After making the diagnosis of endometritis and excluding other sources of infection, the physician should promptly initiate broad-spectrum antibiotics. (medscape.com)
  • Most cases of endometritis, including those following cesarean delivery, should be treated in an inpatient setting. (medscape.com)
  • While nearly all strains of Escherichia coli, Pseudomonas sp and Klebsiella sp, including those that are resistant to gentamicin, kanamycin or other aminoglycosides, are susceptible to amikacin at levels achieved following treatment, it is recommended that the invading organism be cultured and its susceptibility demonstrated as a guide to therapy. (bodaxvet.com)
  • Endometritis is associated with increased maternal mortality due to septic shock. (medscape.com)
  • She was administered cefotaxime, gentamycin and metronidazole parenterally. (jpgo.org)
  • Risk factors for endometritis following delivery include Caesarean section and prolonged rupture of membranes. (wikipedia.org)
  • The study included 500 patients with 255 patients receiving daily dosing of gentamicin and 245 receiving traditional dosing of gentamicin. (qxmd.com)
  • A reduction in cephalopelvic disproportion, repeated cases of endometritis by two-thirds to scars) were enrolled in the study in 2 three-quarters justifies the administration groups, 100 patients in each group. (who.int)
  • 2023. https://im.unboundmedicine.com/medicine/view/Davis-Drug-Guide/109047/11.0/gentamicin. (unboundmedicine.com)
  • The present study demonstrated that the animal model for bubaline endometritis can be developed in mice by intravaginal inoculation of E. coli@ 1.5 × 106 CFU/ml at diestrus. (ac.ir)
  • This study aims to report the handling of endometritis in a dairy cow at Koperasi Agro Niaga Jabung, Malang, Indonesia. (unair.ac.id)
  • Development of a laboratory animal model for bovine endometritis would facilitate the understanding of the pathogenesis as it is difficult to conduct controlled experimentation in the native host. (ac.ir)