Genotyping and genetic. Medical search. Frequent questions

For analysis the genetic diversity of the sub allelic variants of Pvmsp3α and Pvmsp3β genes, Chi-Square test was performed by utilizing Minitab programming software 18. (scielo.br)
In summary, our analysis provides a better understanding of the genetic architecture of autism in isolated populations by highlighting the role of both common and rare gene variants and pointing at new autism-risk genes. (nature.com)
1 The heritability of autism is very high 2 and molecular genetic studies revealed that the genetic risk for autism is shaped by a combination of rare and common variants. (nature.com)
On the contrary, in some cases, the genetic architecture is more complex and involves thousands of common genetic variants, each one with low impact but collectively increasing the susceptibility to autism. (nature.com)
RNA-sequencing (RNA-seq) is a powerful technique for the identification of genetic variants that affect gene-expression levels, either through expression quantitative trait locus (eQTL) mapping or through allele-specific expression (ASE) analysis. (biomedcentral.com)
We also derived genotypes using the RNA-seq reads and used imputation to infer non-coding variants. (biomedcentral.com)
eQTL mapping on individual tissues revealed that a limited number of samples already suffice to identify tissue-specific eQTLs for known disease-associated genetic variants. (biomedcentral.com)
Given the exponential growth of the number of publicly available RNA-seq samples, we expect this approach will become especially relevant for studying the effects of tissue-specific and rare pathogenic genetic variants to aid clinical interpretation of exome and genome sequencing. (biomedcentral.com)
Both rare and common genetic variants have been associated with ADHD. (nature.com)
We performed a genome-wide association study (GWAS) and exome-sequencing analysis to identify common and rare genetic variants associated with plasma myeloperoxidase (MPO)-DNA complex levels, a biomarker for NETs, in the population-based Rotterdam Study cohort. (frontiersin.org)
GWAS was performed using haplotype reference consortium(HRC)-imputed genotypes of common variants in 3,514 individuals from the first and 2,076 individuals from the second cohort of the Rotterdam Study. (frontiersin.org)
Genome-wide association studies (GWAS) and exome-sequencing analysis have been successfully implemented as approaches to identify genetic variants associated with disease susceptibility. (frontiersin.org)
The assessment of genetic variants in association with NETs might help to elucidate potential molecular mechanisms intervening in their formation and their downstream effect on other pathways. (frontiersin.org)
Here, we are the first to apply these approaches to ascertain common and rare genetic variants associated with NETs using data from a population-based cohort study. (frontiersin.org)
Thus, the behavior difference between the groups more likely reflects a G × E interaction, that is, the influence of specific genetic variants manifesting under specific environmental conditions (kennel life). (frontiersin.org)
Investigations have revealed hundreds of genetic variants that influence body weight , and because genes are passed from parents to children, this means that there is an inherited component to obesity. (eatingdisorderhope.com)
Regarding genes and obesity, you can inherit any number of genetic variants that could contribute to weight gain , but whether you actually develop obesity will, in most cases, depend on a myriad of other factors. (eatingdisorderhope.com)
This time around, the FDA said its review of 23andMe's newly authorized tests determined that the company "provided sufficient data to show that the tests are accurate," meaning they can correctly identify genetic variants from the sample and can provide "reproducible results. (latimes.com)
The newly approved 23andMe reports focus on specific genetic variants related to 10 diseases or conditions. (latimes.com)
Using a saliva sample, the company looks for specific genetic variants in a customer's DNA that are associated with increased risk of those diseases or conditions. (latimes.com)
There are many things other than genetic variants that can contribute to the development of these diseases or conditions, including environmental or lifestyle factors. (latimes.com)
The MADCaP Array contains more than 1.5 million markers and an imputation backbone that successfully tags over 94% of common genetic variants in African populations. (sciety.org)
Genetic variants were biochemically characterised. (bmj.com)
OBJECTIVES- Genome-wide association studies have dramatically increased the number of common genetic variants that are robustly associated with type 2 diabetes. (diabetesjournals.org)
The AUC for age, BMI, and sex was 0.78, and adding the genetic risk variants only marginally increased this to 0.80. (diabetesjournals.org)
Limited information on phenotypes attributable to RAD21 variants and genotype-phenotype relationships is currently published. (springer.com)
Variants were frequently familial, and genotype-phenotype analyses demonstrated striking interfamilial and intrafamilial variability. (springer.com)
Genetic variants (specific mutations or allelles of genes) and their corresponding phenotypic variations in the trait or the disease which the genes controls. (bvsalud.org)

Genetic parameters, correlations, and partial regressions were estimated for all the traits. (ccsenet.org)
Conclusion Our study delineates the most common features of PPP2R5D -related neurodevelopmental disorders, expands the clinical and molecular spectrum and identifies genotype-phenotype correlations. (bmj.com)
Correlations between the factor VII genotype, factor VII clotting activity and the clinical phenotype are not tight. (medscape.com)
Correlations between imaging phenotype and genotype. (bvsalud.org)

A multilocus genotype is the combination of alleles found at two or more loci in a single individual. (wikipedia.org)
For example, in a diploid species, if there are two SNP loci and the first locus has alleles A and G, while the second locus has alleles T and C, the multilocus genotype can be represented as {A/G,T/C}. If the genome is not haploid then the multilocus genotype does not necessarily determine which alleles co-occur on chromosomes. (wikipedia.org)
The combination of alleles at two or more loci on a single chromosome make up a haplotype and the two haplotypes in a diploid individual make up the diplotype (a synonym for a phased multilocus genotype). (wikipedia.org)
In genome-wide association studies (GWAS) genetic loci that influence complex traits are localized by inspecting associations between genotypes of genetic markers and the values of the trait of interest. (lu.se)
The genetic map was constructed based on the genotypic data of 140 RILs and included a total of 14,088 markers grouped into 2,296 genetic loci in 14 linkage groups, corresponding to the 14 chromosomes of tetraploid wheat. (huji.ac.il)
We have developed an Africa-specific genotyping array which enables investigators to identify novel disease associations and to fine-map genetic loci that are associated with prostate and other cancers. (sciety.org)
Fifteen CaPsol lineages were identified based on distinct combinations of sequence variations within these genetic loci. (univr.it)

Data -- More than one genotype: How common is intracolonial genetic variability in scleractinian corals? (datadryad.org)
In recent years, a few colonial marine invertebrates have shown intracolonial genetic variability, a previously unreported phenomenon. (datadryad.org)
Intracolonial genetic variability describes the occurrence of more than a single genotype within an individual colony. (datadryad.org)
We investigate the occurrence of intracolonial genetic variability in five scleractinian corals: Acropora florida, Acropora hyacinthus, Acropora sarmentosa, Pocillopora species complex and Porites australiensis. (datadryad.org)
Our results show that intracolonial genetic variability was common (between 46.6% for A. sarmentosa and 23.8% for P. species complex) in all tested corals. (datadryad.org)
This suggests that intracolonial genetic variability is widespread in scleractinian corals and could challenge the view of a coral colony as an individual and therefore a unit of selection. (datadryad.org)
Eighty six promising new barley genotypes and three checks including one indigenous cultivar ( Hordeum vulgare L. var Rum) were grown in two successive seasons of 2005 and 2006 to assess the presence of variability for desired traits and amount of variation for different parameters. (ccsenet.org)
On the other hand, dogs bred and kept solely for breeding or research purposes ("kenneled dogs") are kept and handled under standardized conditions, and are usually of the same breed, thus the effects of environmental and breed-specific genetic variability on their individual behavioral variability is small. (frontiersin.org)
To analyze genetic variability of 48 brinjal genotypes by Simple Sequence Repeat (SSR) markers, four primers named smSSR01, smSSR03, smSSR11 and smSSR14 were selected for analyze the data. (academicjournals.org)

According to 23andMe, GSR can be paired with its mobile API for ResearchKit, enabling researchers to create apps for collecting phenotypes from participants that can be studied with genotype data. (genomeweb.com)
PRS can also be used to examine the genetic association between two different diseases or phenotypes. (nature.com)

Our main goal was to evaluate adaptive responses in Scots pine at phenotype and genotype levels. (gu.se)

Whole-genome analysis showed 90.4% identity with other genotype 5 viruses from humans. (cdc.gov)
Humans have a long history of genetic adaptation that favors the storage of fat, drive to consume tasty, energy-dense foods, and restoration of body weight after weight loss - often referred to as the "Thrifty Gene" which promoted survival of the species. (eatingdisorderhope.com)

Furthermore, most genome-wide association studies have used genotyping arrays that are hindered by SNP ascertainment bias. (sciety.org)

With increasing single-nucleotide polymorphism (SNP) discovery from ongoing Plasmodium genome sequencing projects, a demand for high SNP and sample throughput genotyping platforms for large-scale population genetic studies is required. (ox.ac.uk)
Here we used a computational strategy to identify MDD subtypes based on single-nucleotide polymorphism genotyping data from MDD cases and controls using Hamming distance and cluster analysis. (urosario.edu.co)

Present study was designed to explore the genetic diversity of plasmodium vivax genotypes based on Pvmsp-3α and Pvmsp - 3β genes using allelic specific nested PCR and RFLP assays markers from field isolates in district Mardan, Pakistan. (scielo.br)
In a joint analysis on the 1,262 samples with high quality genotypes, we identified cis- eQTLs effects for 8,034 unique genes (at a false discovery rate ≤0.05). (biomedcentral.com)
Genetic studies have repeatedly implicated the DYX2 locus, specifically the genes DCDC2 and KIAA0319 , in RD, with recent studies suggesting they also influence LI, verbal language, and cognition. (springer.com)

Stochastic computer simulations were used for quantifying the effect of selecting on prion protein (PrP) genotype on the risk of major outbreaks of classical scrapie and the rate of genetic progress in performance in commercial sheep populations already undergoing selection on performance. (gla.ac.uk)
900 seedlings from 24 populations were genotyped using genotyping-by-sequencing (GBS). (gu.se)
You want to download Divergent pattern between phenotypic and genetic variation in Scots pine - 746 unrelated genotyped Pinus sylvestris from 24 different populations across Northern Europe from the SND research data catalogue. (gu.se)
Several studies investigated families with autism from countries where consanguinity is high, 6 but the genetic architecture of autism in isolated populations remains largely unknown. (nature.com)
Clear resolution of geographically distinct populations was demonstrated using Principal Components Analysis (PCA), and global patterns of population genetic diversity were consistent with previous reports. (ox.ac.uk)
To assess if the behavioral difference between the family and kenneled dogs could be due to genetic divergence of these two populations and/or to lower genetic diversity of the kenneled dogs, we analyzed their genetic structure using 11 microsatellite markers. (frontiersin.org)
We found no significant difference between the populations in their genetic diversity (i.e., heterozygosity, level of inbreeding), nor any evidence that the family and kenneled populations originated from different genetic pools. (frontiersin.org)
However, no studies have addressed APOE genotyping in Amazonian exposed populations. (chewbook.com)
Additionally, epidemiological studies with APOE genotyping in Amazon have been restricted to indigenous populations. (chewbook.com)
To overcome these disparities in genomic medicine, the M en of A frican D escent and Ca rcinoma of the P rostate (MADCaP) Network has developed a genotyping array that is optimized for African populations. (sciety.org)
Findings from the present study provide new insights into the genetic diversity and ecology of CaPsol populations in vineyards. (univr.it)

But this link will help explain genetic codes in hamsters - Genetics and Inheritance and also this link has Syrian colours Syrian . (hamstercentral.com)
Moreover, exploring the genetic background of their higher resilience could also help to better understand the genetics behind stress- and fear-related behaviors. (frontiersin.org)

On the other hand, eQTL analyses can be used for any genetic variant, but typically require the use of dozens of samples in order to have sufficient individuals in the different genotype classes. (biomedcentral.com)
One hundred and ninety-three healthy Chinese Dai volunteers were identified with respect to CYP2C19 by genotype and phenotype analyses. (nih.gov)
This ultra-dense SNP-based genetic map with a high level of synteny to barley provides a useful framework for genetic analyses of important traits, positional cloning and marker-assisted selection, as well as for comparative genomics and genome organization studies in wheat and other cereals. (huji.ac.il)

Participants that receive 23andMe's test through GSR can log onto the company's site and, like any other 23andMe customer, view their genotyped results on ancestry, traits, and wellness, as well as their US Food and Drug Administration-cleared carrier status reports. (genomeweb.com)
1. When compared with the scenario where there was no selection on PrP genotype, selection against the VRQ allele had a minimal impact on genetic progress for performance traits. (gla.ac.uk)
We investigated a possible genetic association between ADHD and narcolepsy traits in the Hamamatsu Birth Cohort for mothers and children (HBC study) ( n = 876). (nature.com)
Genotype refers to the genetic makeup of the cells in the body, the actual biological traits that are inherited. (eatingdisorderhope.com)
These reports also include details on an individual's ancestry, genetic traits and whether a customer is a carrier for certain diseases. (latimes.com)

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay. (ox.ac.uk)
The wheat 90K iSelect SNP genotyping assay was used for genotyping of the RILs, detecting segregation for 16,387 polymorphic markers. (huji.ac.il)

We evaluated the genetic variation in rs8099917, substitutions in core amino acid (aa) 70, and the number of aa substitutions in the interferon sensitivity-determining region (ISDR) on the prediction of sustained virological response (SVR) in treatment-naïve hepatitis C virus (HCV) genotype 1b (G1b) patients. (hindawi.com)
In treatment-naïve patients, the genetic variation near the interleukin-28B (IL-28B) gene and amino acid (aa) substitution in the core 70 (core aa 70) of HCV may be the candidate predictors of the virological response to triple therapy. (hindawi.com)
The present investigation regarding study of genetic variation of 15 genotypes including Pusa Ruby of cherry tomato (Solanum lycopersicum L. var. (envirobiotechjournals.com)
Since all tobacco products share the ability of stimulating the dopaminergic reward system, variation in the DRD2 genotype might be associated with waterpipe smoking addiction. (who.int)

He has previously studied the security of consumer genetic services and was the first to demonstrate that molecular information, like DNA, can be a possible vector for malware. (ndss-symposium.org)
However, further studies involving large number of genotypes and primers need to be conducted to get more precise information and help enhance the knowledge of students and researchers relating to molecular characterization of other solanaceious crops. (academicjournals.org)
In this review, we describe the genetic diversity of HTLV-1, and analyze the molecular mechanisms that are at play in HTLV-1 evolution. (biomedcentral.com)
The related report by Yang et al, 'Rapid Genotyping of SNPs Influencing Warfarin Drug Response by SELDI-TOF Mass Spectrometry,' appears in the March 2010 issue of the Journal of Molecular Diagnostics . (news-medical.net)

Eighty percent of the SNPs (n = 306) produced reliable genotype calls on samples containing as little as 2 ng of total genomic DNA and on whole genome amplified DNA. (ox.ac.uk)
Researchers from the Ohio State University have developed a rapid, multiplexed genotyping method to identify the single nucleotide polymorphisms (SNPs) that affect warfarin dose. (news-medical.net)
Certain genetic variations, SNPs, also affect warfarin sensitivity and metabolism. (news-medical.net)
A group led by Dr. Haifeng M. Wu of the Ohio State University has developed a new rapid method to genotype SNPs that will help clinicians to choose appropriate doses of warfarin for individual patients. (news-medical.net)
Using surface-enhanced laser desorption and ionization time-of-flight mass spectrometry (SELDI-TOF MS), which can determine the elemental composition of a sample, Yang et al could determine the genotype of three warfarin-related SNPs in under five hours with high levels of accuracy. (news-medical.net)

The main focus was to test different genera for the phenomenon via microsatellite markers and to distinguish which underlying process caused the genetic heterogeneity. (datadryad.org)
We ran a number of experiments that showed how these files could be used in data extraction attacks to uncover private genetic markers from other users in the database. (ndss-symposium.org)
Finally, Circle Premium offers all of the above, and also tests everything from your drug response markers to your genetic predisposition to conditions like dementia and cancer. (livescience.com)
The present study demonstrated that SSR markers are effective for obtaining unique fingerprints of, and assessing genetic diversity among, tomato wild relatives and would be used for wide range of practical application including varietal identification and pre-screening for distinctiveness of tomato genotypes. (envirobiotechjournals.com)
The SSR markers used in the present study were able to differentiate forty eight brinjal genotypes genetically. (academicjournals.org)
the use of issr and rapd markers for detecting dna polymorphism, genotype identification and genetic diversity among trichosanthes dioica roxb. (academicjournals.org)
Genomic ancestry markers were evaluated by multiplex-PCR reaction, separated by capillary electrophoresis on the ABI 3130 Genetic Analyzer instrument and analyzed on GeneMapper ID v3.2. (chewbook.com)

Genetic diversity in nested PCR products was determined by Restriction Fragment Length Polymorphism (RFLP) utilizing Alu1 and PstI restriction enzymes for alpha and beta gene products digestion, respectively. (scielo.br)
A polymerase chain reaction-restriction fragment length polymorphism method was performed for genotyping procedures. (nih.gov)

Few studies have been conducted on the epidemiology of waterpipe smoking behavior and its genetic determinants. (who.int)

Grain yield per plant showed high significant positive genetic and phenotypic correlation with only number of kernels per main spike. (ccsenet.org)

NEW YORK (GenomeWeb) - 23andMe has launched its Genotyping Services for Research (GSR) platform which it hopes will help streamline scientists' ability to integrate genetic data into their studies and give study participants something back for their contribution. (genomeweb.com)
Gadelrab believes that providing patients access to genetic data may provide "a huge advantage in recruiting. (genomeweb.com)
Hi R users, Does any one know a R package for genetic analysis of VNTR (variable number of tandem repeats) genotype data? (ethz.ch)
The genotype data allow evaluation of genetic variance across landscapes and thus shed light on the degree of genetic-environmental association and the recolonization history of Scots pine in Scandinavia. (gu.se)
Given increasing numbers of RNA-seq samples in the public domain, we here studied to what extent eQTLs and ASE effects can be identified when using public RNA-seq data while deriving the genotypes from the RNA-sequencing reads themselves. (biomedcentral.com)
By deriving and imputing genotypes from RNA-seq data, it is possible to identify both eQTLs and ASE effects. (biomedcentral.com)
Some authors suggest that the term multilocus genotype should only be applied to phased multilocus data while others apply it to unphased multilocus data as well. (wikipedia.org)
Simulation studies and a real data example illustrate the advantages of this new approach compared to single-marker analysis or modern model selection strategies based on separately analyzing genotype and ancestry data, as well as to single-marker analysis combining genotypic and ancestry information. (lu.se)
This type of analysis, known as genetic genealogy, is often performed by third-party web services that aggregate consumer genetic data from different companies to make relative inferences. (ndss-symposium.org)
These third-party services have important implications for genetic privacy because of the amount of genetic data they store - sometimes exceeding millions of genetic profiles - and the recent use of genetic genealogy in new domains like criminal investigations. (ndss-symposium.org)
To understand these risks we constructed artificial genetic data files using publicly available genetic sources and uploaded them to the leading third-party genetic genealogy service. (ndss-symposium.org)
In a second set of experiments we showed how artificial genetic data could be constructed to imply false genetic relationships in the database. (ndss-symposium.org)
An open question is whether these artificial genetic data files could be used by an attacker to avoid identification, especially in a criminal investigation. (ndss-symposium.org)
The company removed health-related results from its genetic tests after this warning, providing only ancestry information and raw genetic data without interpretation. (latimes.com)
The genetic distance (GD) between genotypes was computed from combined data for the four primers, ranging from 0.250 to 1.000. (academicjournals.org)
To understand genetic relationships among these cultivars, Jaccard's similarity coefficient and UPGMA clustering algorithm were applied to the two marker data sets. (academicjournals.org)
Although a few data-driven attempts have been made to identify more homogenous subgroups within MDD, other studies have not focused on using human genetic data for MDD subtyping. (urosario.edu.co)
Advances in this line of research to validate this strategy in other patient groups of different ethnicities will have the potential to eventually be translated to clinical practice, with the tantalising possibility that in the future it may be possible to refine MDD diagnosis based on genetic data. (urosario.edu.co)
Deep data analytics for genetic engineering of diatoms linking genotype to phenotype via machine learning. (ornl.gov)
Just Added Our Health Action Plan features personalized recommendations based on genetic and non-genetic data, including blood test data. (23andme.com)
If you want to get a more complete picture of your health with insights from your genetic data. (23andme.com)

The Unweighed Pair Group Method with Arithmetic Means (UPGMA) cluster tree analysis lead to the grouping of the 48 genotypes into seven major clusters and the genotypes that are derivatives of genetically similar type form cluster together. (academicjournals.org)

Assessment of genetic diversity in cherry tomato (solanum lycopersicum l. var. (envirobiotechjournals.com)

In the clinical world, he said, genetic risk is used only occasionally as supportive evidence. (latimes.com)
3. Clinical diagnosis of achondroplasia (ACH) with genetic confirmation of heterozygous genotype present during screening. (who.int)

5. How do you write a genetic code for a hamster 'who carries, or carrier' a certain gene? (hamstercentral.com)
Previous genetic studies indicated that individuals from Scotland, Norway, Sweden, Ireland, Iceland, and British Isles have significantly contributed to the current gene pool of the Faroese population. (nature.com)
Genetic susceptibility to CBD is associated with alleles of the major histocompatibility gene, human leukocyte antigen DP (HLA-DP) containing glutamic acid at the 69th position of the beta chain (HLA-DPbeta-E69). (cdc.gov)
AIM: This study aims to explore genetic variations in DRD2 gene and waterpipe smoking, motives and addiction in Egyptian rural males. (who.int)

However, studies on the genetic susceptibility to mercury toxicity in the Amazon are scarce, and they tested a limited number of individuals. (chewbook.com)

However, the envelope protein contained Lys 84, which was specific to strains of genotype 5 viruses from South Korea. (cdc.gov)
We report isolation of JEV genotype 5 virus from patient specimens and differences in sequences among other JEV strains (genotypes 1-5). (cdc.gov)
We compared the entire ORF sequences of K15P38 virus with previously reported strains of JEV genotypes 1-5. (cdc.gov)
HTLV-1 exhibits a remarkable genetic stability, however, viral strains have been classified in several genotypes and subgroups, which often mirror the geographic origin of the viral strain. (biomedcentral.com)
While strains from the HTLV-1d genotype represent only a few percent of the strains present in Central African countries, genotypes -e, -f, and -g have been only reported sporadically in particular in Cameroon Gabon, and Central African Republic. (biomedcentral.com)

After getting IRB approval to return genetic test results to participants, researchers can order spit kits online from 23andMe, and send them to participants' homes or to the study site. (genomeweb.com)
Genetic testing firm 23andMe got approval from the Food and Drug Administration last week to sell reports that show customers whether they have an increased genetic risk of developing certain diseases and conditions. (latimes.com)
The go-ahead is the first time the federal agency has approved such direct-to-consumer genetic tests and comes about three years after the FDA warned Mountain View, Calif.-based 23andMe to stop marketing its health reports because they lacked agency authorization. (latimes.com)

Attention Deficit/ hyperactivity Disorder (ADHD): Complex Phenotype, Simple Genotype. (bvsalud.org)

Analysis of artificial mixtures of laboratory clones demonstrated high genotype calling specificity and moderate sensitivity to call minor frequency alleles. (ox.ac.uk)
Four primers generated clear bands and a total of 44 alleles were detected among the 48 brinjal genotypes (9.0 to 14.0 alleles per locus with a mean of 11.0 alleles per locus). (academicjournals.org)

Recently it has been proposed to jointly model genotype and locus-specific ancestry within the framework of single marker tests. (lu.se)

With the help of a genetic structure analysis carried out on 25 Ae. (pasteur.fr)
Mathematical and Statistical Methods for Genetic Analysis. (wikipedia.org)
The CYP2C19 genotype analysis is largely consistent with the mephenytoin phenotype analysis. (nih.gov)
Diet Fit, which is the kit we've tested here, offers you analysis of your dietary and nutrient needs based on your genetic information. (livescience.com)

HTLV-1c genotype, which is found exclusively in Australo-Melanesia, is the most divergent genotype. (biomedcentral.com)

However, genotype 5 was also identified in mosquitoes in South Korea ( 3 ). (cdc.gov)
Since that time, JEV genotype 5 has been detected in mosquitoes in many areas of South Korea ( 4 ). (cdc.gov)
Chikungunya: the specific interactions between the genotypes of mosquitoes and viruses have influenced Ae. (pasteur.fr)
Thus, the specific interactions between the genotypes of mosquitoes and viruses have influenced Ae. (pasteur.fr)

The results of this study will contribute in future studies about the genetic structure of parasite and vaccine development against the malaria. (scielo.br)
Future studies replicating these findings would be warranted to elucidate the genetic vulnerability for daytime sleepiness in individuals with ADHD. (nature.com)
These results validate the utility of the platform in performing population genetic studies of P. falciparum. (ox.ac.uk)
Steps that would directly impact both the power of epidemiologic studies and the cost of surveillance would be to develop and validate improved screening and diagnostic tests, and to identify more genetic factors that affect either sensitization or disease process. (cdc.gov)
Genetic studies, including genotyping, may be warranted for counseling and prenatal diagnosis. (medscape.com)

Our results were validated using samples for which DNA-seq genotypes were available. (biomedcentral.com)
These results suggest that epigenetic factors as well as genotype and maltreatment play a role in the development of alcohol misuse among young adult males. (nih.gov)
The results of the study suggested that SSR can be used as a suitable genetic marker to identify the brinjal genotypes. (academicjournals.org)

More extreme PrP selection strategies aimed at increasing the frequency of the ARR allele and decreasing the frequency of the VRQ allele led to decreases in the rate of genetic progress for performance but reduced the population risk to very low values. (gla.ac.uk)
The reduction in genetic progress was only large when the initial ARR frequency was low and, in general, the risk of major epidemics was very small when the frequency of this allele reached 0.7. (gla.ac.uk)
The 𝜀3 and 𝜀3/𝜀3 were the most frequent allele and genotype, respectively, followed by 𝜀4 allele and 𝜀3/𝜀4 genotype. (chewbook.com)

In 2010, JEV genotype 1 was the predominant virus circulating. (cdc.gov)

Reading disability (RD) and language impairment (LI) are common neurodevelopmental disorders with moderately strong genetic components and lifelong implications. (springer.com)

Our aim was to evaluate the prevalence of insulin resistance in Egyptian patients with chronic HCV genotype 4 infection, to assess factors associated with insulin resistance and to test the impact of insulin resistance on outcomes of treatment with pegylated interferon/ribavirin. (who.int)

RÉSUMÉ Les associations observées entre le polymorphisme du récepteur de la vitamine D et le diabète de type 1 varie en fonction des groupes ethniques. (who.int)

There were no significant difference between the genotype frequencies and chronic complications of diabetes, but the relationship between the Ff genotype and ketoacidosis was significant. (who.int)

Factor VII plasma levels are influenced by both environmental and genetic factors. (medscape.com)
however, it University of Medical Sciences and in environmental and genetic factors. (who.int)

One recent study conducted in Japan demonstrated that the relative risk of narcolepsy in affected first-degree family members is 10- to 40-fold higher than in the general population, suggesting that genetic factors play an important role in this disease 12 . (nature.com)
In our study we experimentally demonstrated that poor API design by genetic genealogy services can lead to significant security and privacy issues. (ndss-symposium.org)
We assessed the effectiveness of the MADCaP Array by genotyping 399 prostate cancer cases and 403 controls from seven urban study sites in sub-Saharan Africa. (sciety.org)

The major cluster A consists of five genotypes whereas major cluster B consists of rest of 10 genotypes. (envirobiotechjournals.com)
The individuals in this hidden subtype have increased common genetic substrates related to major depression and they also have more anxiety and less middle insomnia, depersonalization and derealisation, and paranoid symptoms. (urosario.edu.co)
it is the major genotype in Gabon, Cameroon and Democratic Republic of Congo. (biomedcentral.com)

Anatomy5

Organisms22

Diseases15

Chemicals and Drugs39

Analytical, Diagnostic and Therapeutic Techniques and Equipment68

Psychiatry and Psychology2

Phenomena and Processes73

Disciplines and Occupations14

Anthropology, Education, Sociology and Social Phenomena5

Technology, Industry, Agriculture3

Information Science11

Named Groups5

Health Care20

Geographicals16

Variants28

Correlations4

Loci7

Variability9

Phenotypes2

Phenotype and genotype1

Humans2

Genome-wide as1

Single Nucleotide P2

Genes3

Populations11

Genetics2

Analyses3

Traits5

Assay2

Variation4

Molecular4

SNPs5

Markers7

Polymorphism2

Epidemiology1

Phenotypic1

Data21

Clusters1

Solanum1

Clinical2

Gene4

Susceptibility1

Strains5

23andMe3

Attention deficit1

Alleles2

Ancestry1

Analysis4

Divergent1

Mosquitoes4

Studies5

Results3

Allele3

Predominant1

Neurodevelopmental1

Evaluate1

Associations1

Chronic1

Environmental and genetic factors2

Study3

Major3