DNA DamageMutagensStress, PhysiologicalTumor Suppressor Protein p53Ataxia Telangiectasia Mutated ProteinsMutagenicity TestsCell Cycle ProteinsMethyl MethanesulfonateUltraviolet RaysDNA RepairApoptosisRadiation, IonizingDNA-Binding ProteinsProtein-Serine-Threonine KinasesTumor Suppressor ProteinsCell CycleOxidative StressGamma RaysComet AssayCell Line, TumorSignal TransductionNuclear ProteinsPhosphorylationMutationGenomic InstabilityTranscription FactorsCell LineCRADD Signaling Adaptor ProteinHeat-Shock ResponseProto-Oncogene Proteins c-mdm2Cell SurvivalGene Expression RegulationCheckpoint Kinase 2Molecular Sequence DataDoxorubicinTranscription, GeneticG2 PhaseProto-Oncogene Proteins c-ablDNA Breaks, Double-StrandedGene Expression ProfilingFibroblastsHCT116 CellsProtein Binding