Genotoxic stress dna damage. Medical search. Frequent questions

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Anatomy21

Cell Line, Tumor Cell Line Fibroblasts Micronuclei, Chromosome-Defective HCT116 Cells HeLa Cells Cell Nucleus Cells, Cultured Chromatin Tumor Cells, Cultured HEK293 Cells Lymphocytes Cell Line, Transformed Mitochondria NIH 3T3 Cells Embryo, Mammalian Cytoplasm Epithelial Cells Keratinocytes Telomere Liver

Organisms5

Mice, Knockout Saccharomyces cerevisiae Mice, Inbred C57BL Cricetinae Schizosaccharomyces

Diseases6

Genomic Instability Micronuclei, Chromosome-Defective Ataxia Telangiectasia Chromosome Aberrations Neoplasms Cell Transformation, Neoplastic

Chemicals and Drugs124

DNA Mutagens Tumor Suppressor Protein p53 Ataxia Telangiectasia Mutated Proteins Cell Cycle Proteins Methyl Methanesulfonate Tumor Suppressor Proteins DNA-Binding Proteins Protein-Serine-Threonine Kinases Checkpoint Kinase 2 Nuclear Proteins Histones Deoxyguanosine Proto-Oncogene Proteins c-mdm2 DNA Adducts DNA Repair Enzymes Poly(ADP-ribose) Polymerases Protein Kinases Doxorubicin CRADD Signaling Adaptor Protein Cyclin-Dependent Kinase Inhibitor p21 Hydroxyurea Mitomycin Poly Adenosine Diphosphate Ribose Etoposide Alkylating Agents RNA, Small Interfering Proto-Oncogene Proteins c-abl Intracellular Signaling Peptides and Proteins Carcinogens cdc25 Phosphatases Saccharomyces cerevisiae Proteins Reactive Oxygen Species Hydrogen Peroxide Replication Protein A Ubiquitin Rad51 Recombinase Transcription Factors Cisplatin BRCA1 Protein Methylnitronitrosoguanidine Chromatin Antimutagenic Agents DNA-Activated Protein Kinase Antineoplastic Agents Caspase 2 Antibiotics, Antineoplastic Ubiquitin-Protein Ligases DNA Helicases rhoB GTP-Binding Protein Cyclins RNA, Messenger Antigens, Nuclear DNA Glycosylases Proliferating Cell Nuclear Antigen Camptothecin zeta-Crystallins Proto-Oncogene Proteins Apoptosis Regulatory Proteins Endonucleases Sirtuin 1 DNA-(Apurinic or Apyrimidinic Site) Lyase CDC2 Protein Kinase Histone Acetyltransferases Death Domain Receptor Signaling Adaptor Proteins Multiprotein Complexes Benzo(a)pyrene Serine SUMO-1 Protein Proteasome Endopeptidase Complex Carrier Proteins Chromosomal Proteins, Non-Histone Caspase 3 Enzyme Inhibitors Proto-Oncogene Proteins c-bcl-2 Carcinogens, Environmental Antioxidants 4-Nitroquinoline-1-oxide Caspases Lysine Ribonucleotide Reductases Cyclin B Xeroderma Pigmentosum Group A Protein DNA-Formamidopyrimidine Glycosylase bcl-2-Associated X Protein DNA Primers Chromium Bleomycin DNA, Neoplasm Recombinant Fusion Proteins Caffeine Adaptor Proteins, Signal Transducing Guanine E2F4 Transcription Factor Repressor Proteins Nucleic Acid Synthesis Inhibitors Pyrimidine Dimers Proteins Mutant Proteins Chromates DNA, Fungal Plant Extracts 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide Oxidants Endodeoxyribonucleases Protein Kinase C-delta Cyclin-Dependent Kinases Trans-Activators NF-kappa B Schizosaccharomyces pombe Proteins Retinoblastoma Protein Phosphoproteins bcl-X Protein Exodeoxyribonucleases Neoplasm Proteins Green Fluorescent Proteins I-kappa B Kinase Polycyclic Hydrocarbons, Aromatic RNA-Binding Proteins Protein Isoforms Mitogen-Activated Protein Kinases Phosphoprotein Phosphatases Glutathione Transferase p38 Mitogen-Activated Protein Kinases

Analytical, Diagnostic and Therapeutic Techniques and Equipment21

Comet Assay Mutagenicity Tests Dose-Response Relationship, Radiation Models, Biological Blotting, Western Transfection Flow Cytometry Gene Knockdown Techniques Immunoblotting Reverse Transcriptase Polymerase Chain Reaction Micronucleus Tests Microscopy, Fluorescence Immunoprecipitation Chromatin Immunoprecipitation Gene Expression Profiling Carcinogenicity Tests Models, Genetic Immunohistochemistry Oligonucleotide Array Sequence Analysis Fluorescent Antibody Technique In Situ Nick-End Labeling

Phenomena and Processes82

DNA Damage DNA Repair Ultraviolet Rays Apoptosis Cell Cycle Gamma Rays DNA Breaks, Double-Stranded Genomic Instability Radiation, Ionizing Phosphorylation G2 Phase Oxidative Stress Mutation Cell Survival Signal Transduction DNA Replication S Phase DNA Adducts Micronuclei, Chromosome-Defective Cell Cycle Checkpoints Cell Aging Radiation Tolerance Mitosis Stress, Physiological Protein Binding Dose-Response Relationship, Radiation Ubiquitination Genes, p53 Gene Expression Regulation Sister Chromatid Exchange Cell Death Transcription, Genetic DNA Breaks Chromatin RNA Interference Time Factors Chromosome Aberrations Sumoylation Enzyme Activation Transfection G1 Phase Base Sequence Transcriptional Activation Dose-Response Relationship, Drug Down-Regulation Cell Proliferation Active Transport, Cell Nucleus Protein Structure, Tertiary Recombination, Genetic DNA Breaks, Single-Stranded Amino Acid Sequence Gene Expression Regulation, Neoplastic Protein Processing, Post-Translational Acetylation Genes, cdc Cell Division Promoter Regions, Genetic Mutagenesis Protein Transport Gene Deletion G2 Phase Cell Cycle Checkpoints Up-Regulation SOS Response (Genetics)X-Rays Phenotype Gene Silencing Plasmids Oxidation-Reduction Gene Expression Drug Resistance, Neoplasm Binding Sites DNA End-Joining Repair Recombinational DNA Repair Gene Expression Regulation, Fungal Lipid Peroxidation DNA Fragmentation Aging Telomere Homologous Recombination Amino Acid Motifs Genes, Reporter Sequence Homology, Amino Acid

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care3

Ultraviolet Rays Dose-Response Relationship, Radiation Occupational Exposure

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science Health Care

DNA Damage DNA Mutagens DNA Repair Tumor Suppressor Protein p53 Comet Assay Ataxia Telangiectasia Mutated Proteins Cell Cycle Proteins Ultraviolet Rays Methyl Methanesulfonate Tumor Suppressor Proteins Mutagenicity Tests DNA-Binding Proteins Protein-Serine-Threonine Kinases Apoptosis Cell Cycle Gamma Rays Checkpoint Kinase 2 DNA Breaks, Double-Stranded Nuclear Proteins Genomic Instability Cell Line, Tumor Radiation, Ionizing Phosphorylation G2 Phase Oxidative Stress Histones Cell Line Mutation Cell Survival Signal Transduction DNA Replication Deoxyguanosine Proto-Oncogene Proteins c-mdm2 S Phase Fibroblasts DNA Adducts DNA Repair Enzymes Poly(ADP-ribose) Polymerases Micronuclei, Chromosome-Defective Protein Kinases HCT116 Cells Cell Cycle Checkpoints Doxorubicin CRADD Signaling Adaptor Protein HeLa Cells Cyclin-Dependent Kinase Inhibitor p21 Hydroxyurea Cell Nucleus Cell Aging Cells, Cultured Radiation Tolerance Mitosis Stress, Physiological Protein Binding Mitomycin Dose-Response Relationship, Radiation Poly Adenosine Diphosphate Ribose Etoposide Alkylating Agents RNA, Small Interfering Proto-Oncogene Proteins c-abl Ubiquitination Intracellular Signaling Peptides and Proteins Carcinogens Genes, p53 cdc25 Phosphatases Saccharomyces cerevisiae Proteins Reactive Oxygen Species Hydrogen Peroxide Replication Protein A Gene Expression Regulation Ataxia Telangiectasia Ubiquitin Molecular Sequence Data Models, Biological Sister Chromatid Exchange Rad51 Recombinase Cell Death Transcription Factors Transcription, Genetic Cisplatin BRCA1 Protein DNA Breaks Methylnitronitrosoguanidine Chromatin RNA Interference Antimutagenic Agents DNA-Activated Protein Kinase Mice, Knockout Saccharomyces cerevisiae Time Factors Antineoplastic Agents Tumor Cells, Cultured Blotting, Western Chromosome Aberrations Sumoylation Enzyme Activation Transfection Caspase 2

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