Genomics tandem repeat sequences. Medical search. Frequent questions

Exploring genetic variation in the tomato ( Solanum section Lycopersicon) clade by whole-genome sequencing. (genomeweb.com)
Variant detection sensitivity and biases in whole genome and exome sequencing. (genomeweb.com)
Whole-genome sequence analysis reveals differences in population management and selection of European low-input pig breeds. (genomeweb.com)
The researchers used a whole-genome shotgun sequencing strategy and constructed 37 paired-end libraries with an average read length of 52 base pairs. (genomeweb.com)
Whole genome sequencing of Salmonella Typhimurium 12. (who.int)
4. Expert opinion on whole genome sequencing for public health sur- ratory surveillance. (who.int)
It requires not only finding the nucleotide sequence of small pieces of the genome, but also ordering those small pieces together into the whole genome. (learner.org)
Two general strategies have been used in the sequencing of large genomes: clone-based sequencing and whole genome sequencing (Fig. 1). (learner.org)
The increasing accessibility of whole-genome sequencing across research and clinical settings has improved our ability to predict antibacterial susceptibility, to track epidemics at the level of individual outbreaks and wider historical trends, to query the efficacy of the bacille Calmette-Guérin (BCG) vaccine, and to uncover targets for novel antitubercular therapeutics. (jci.org)
Whole-genome sequencing (WGS) of M. tuberculosis and related mycobacteria is now routine, allowing comparisons across time and space. (jci.org)
Integration of whole genome sequencing into a healthcare setting: high diagnostic rates across multiple clinical entities in 3219 rare disease patients. (scilifelab.se)
We report the findings from 4437 individuals (3219 patients and 1218 relatives) who have been analyzed by whole genome sequencing (WGS) at the Genomic Medicine Center Karolinska-Rare Diseases (GMCK-RD) since mid-2015. (scilifelab.se)
We measured sperm mosaicism using deep-whole-genome sequencing, for variants both present in an offspring and evident only in father's sperm, and identified single-nucleotide, structural and short tandem-repeat variants. (nih.gov)
There is evidence that it may be caused by a nonsense mutation in the TANC2 gene, which was found during whole-genome sequencing of a Chinese boy (Tian et al. (defeatingepilepsy.org)
Whole-genome sequencing has also provided evidence for two tandem repeat expansions in patients with Lennox-Gastaut Syndrome, a CGG repeat expansion in the 5' untranslated region of the DIP2B gene, and a CTG expansion in the ATXN8OS gene. (defeatingepilepsy.org)
Use whole genome sequencing to study how and why certain fungi spread and make people sick. (cdc.gov)
oocysts and extract DNA in order to obtain high-quality whole genome sequences with minimum contamination of DNA from other organisms. (cdc.gov)

Simple sequence repeats (SSRs) are highly variable features of all genomes. (biomedcentral.com)
BES analyses identified 6,848 simple sequence repeats (SSRs), of which 3,854 had high quality flanking sequences for PCR primers design. (biomedcentral.com)
Microsatellites (short tandem repeats, STR, or simple sequence repeats, SSR) are widely used markers in population genetics. (cd-genomics.com)
They are also known as short tandem repeats (STRs) or simple sequence repeats (SSRs). (vajiramandravi.com)

Sequence analysis of the Daphnia pulex genome holds some surprises that could not have been anticipated from what was learned so far from other arthropod genomes. (biomedcentral.com)
Long terminal repeat (LTR) retroelements represent a successful group of transposable elements (TEs) that have played an important role in shaping the structure of many eukaryotic genomes. (biomedcentral.com)
Last week, the BGI team published results from de novo assemblies of two human genomes using the Illumina technology ( see In Sequence 12/8/2009 ). (genomeweb.com)
The number of publicly available genome assemblies from the International Nucleotide Sequence Database Collaboration (INSDC) [ 1 ] has reached thousands of animal genomes and millions of bacteria and viruses. (biomedcentral.com)
A different approach to solve the increase in genomes is "crowd-sourcing" the problem to research labs who sequence these genomes. (biomedcentral.com)
Also, beyond the display of annotations, our popular sequence search tool BLAT [ 8 ] is essential when working with genomes but requires one powerful server per genome as the entire sequence index needs to be permanently kept in memory. (biomedcentral.com)
As part of large nation-wide population genomics programs, we map the natural variation in healthy genomes. (ccmb.res.in)
In order to better understand the genomic forces driving the evolution of Echinochloa species toward weed and crop characteristics, we assemble genomes of three Echinochloa species (allohexaploid E. crus-galli and E. colona , and allotetraploid E. oryzicola ) and re-sequence 737 accessions of barnyard grasses and millets from 16 rice-producing countries. (nature.com)
By 2003 biologists had sequenced genomes from about one hundred different species. (learner.org)

Computing for Comparative Microbial Genomics: Bioinformatics for Microbiologists. (wikipedia.org)
Related articles have been published in supplements to BMC Bioinformatics , BMC Genomics , BMC Medical Informatics and Decision Making and BMC Systems Biology . (biomedcentral.com)
NAR Genomics and Bioinformatics 4(4), article number: lqac089. (cardiff.ac.uk)
Article: An integrative approach for codon repeats evolutionary analyses Journal: International Journal of Data Mining and Bioinformatics (IJDMB) 2012 Vol.6 No.4 pp.369 - 381 Abstract: The relationship between genome characteristics and several human diseases has been a central research goal in genomics. (inderscience.com)

Microsatellites (Short sequence repeats, SSRs, Short tandem repeats): are short (1-6bp) repeating sequences in genetic code. (flashcardmachine.com)
CD Genomics provided a technology called Hi-SSRseq that combined the multiplexed amplification of traditional SSRs with high throughput sequencing. (cd-genomics.com)

With state-of-the-art sequencing platforms and deep collaboration with highly experienced technicians and scientists across departments in CD Genomics, an Hi-SSRseq technique is offered that allows to genotype hundreds of individuals at many custom‐designed SSR loci simultaneously, combining multiplex PCR and Illumina sequencing. (cd-genomics.com)
Scientists at the Beijing Genomics Institute in Shenzhen reported this week in Nature that they sequenced and assembled a draft genome of the giant panda using only the Illumina Genome Analyzer platform and the SOAPdenovo algorithm for assembly. (genomeweb.com)
Wang said the study showed that short-read technology such as the Illumina Genome Analyzer is appropriate for generating mammalian draft genome sequences. (genomeweb.com)
Samplix provides target enrichment services using the Xdrop platform together with Oxford Nanopore and/or Illumina sequencing. (lpmhealthcare.com)
Genomic DNA was used to construct Ovation Ultralow libraries for Illumina sequencing. (cdc.gov)

SSR-seq: Genotyping of microsatellites using next-generation sequencing reveals higher level of polymorphism as compared to traditional fragment size scoring. (cd-genomics.com)
Microsatellites are small DNA sequences made up of repeating units. (vajiramandravi.com)

In the last years a special interest in the field of mosquitoes' genomics is highlighted by the completion of three genomic sequences (i.e. (uniba.it)
Hello Amit, The genomic sequences hosted on Galaxy are from UCSC and according to their convention repeats from RepeatMasker and Tandem Repeats Finder (with a period of 12 or less) are shown in lower case and non- repeating sequence is shown in upper case. (usegalaxy.org)
I tried to retrieve a set of 20 bp length genomic sequences using the UCSC Table Browser, using. (usegalaxy.org)
The Benson lab develops algorithms and software for biological sequence comparison and repeat detection in genomic sequences. (bu.edu)
By using next generation sequencing, genomic sequences can be obtained and compared to identify potential genotyping markers. (cdc.gov)
MiSeq sequencing reads were taxonomically profiled for contamination, de novo assembled, and mapped to a draft genome available in GenBank to assess the quality of the resulting genomic sequences. (cdc.gov)
The methods described here will facilitate the accumulation of genomic sequences from various samples, which is a prerequisite for the development of typing tools to aid in outbreak investigations. (cdc.gov)

2020. De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia . (cardiff.ac.uk)
I am using a whole exome sequencing dataset to look for potential pathogenic mutations. (usegalaxy.org)
Mutational genomics and targeted exome capture identify Sr26 and Sr61 as separate single genes that encode unrelated (34.8%) nucleotide binding site leucine rich repeat proteins. (nature.com)

Amplification of the promoter region ( ptxP ) and ptxA was also unsuccessful during multilocus sequence typing targeting acellular vaccine component genes ptxA , ptxP , prn , and fim3 ( 8 ). (cdc.gov)
Furthermore, comparative genomics through BES can be used for identifying positional candidate genes from QTL mapping studies, aid in future assembly of a reference genome sequence and elucidating sequence content and complexity in the rainbow trout genome. (biomedcentral.com)
Genomic Sequencing: Who Controls The Information Your Genes Contain? (medicaldaily.com)
Dear Galaxy, I have the results for the sequence retrieval for Insulator regions in the human genome and I am having difficulty in comprehending the upper and lower case associated with my sequences.I know it for sure that they are regions which do not in any way overlap with exons or introns and are that between any 2 genes. (usegalaxy.org)
However, several open questions still remain, such as, how these tandem repeats appeared in the evolutionary path or how they have evolved in orthologous genes of related organisms. (inderscience.com)
The first stage involved identifying, in unrelated subjects showing linkage to 2q24-q33, genetic variants in exons and flanking sequence within candidate genes and comparing the frequency of the variants between autistic and unrelated nonautistic subjects. (neurotransmitter.net)
He was at the origins of the introduction of DNA analysis into forensic medical examination in our country, participated in the discovery of genes key to Alzheimer's disease, was one of the first in Russia to start working with ancient DNA and sequenced the mitochondrial genome of a mammoth. (vechnayamolodost.ru)
While we were doing this article for two years, some of these genes were gradually added to the reference sequence of the genome, which confirmed the validity of our approach. (vechnayamolodost.ru)

Direct repeats are a type of genetic sequence that consists of two or more repeats of a specific sequence. (wikipedia.org)
Current sequencing technology makes microhaplotypes a powerful new type of genetic marker for forensics. (genomeweb.com)
Fast and cost-effective genetic mapping in apple using next-generation sequencing. (genomeweb.com)
As one of the most studied genome rearrangements, tandem repeats have a considerable impact on genetic backgrounds of inherited diseases. (biomedcentral.com)
Microsatellite DNA is utilised in genetic analysis, more specifically in molecular genetics and genomics. (vajiramandravi.com)
First, we identify genetic variation of individuals using cutting-edge high throughput sequencing technologies. (ccmb.res.in)
We empower them to attain a unique in-depth comprehension of the genetic makeup underlying diseases, a feat made possible only through the utilization of the most sophisticated DNA sequencing technologies. (sequegenics.com)
Samplix ® provides researchers with tailored genomics tools to solve complex genetic landscapes. (lpmhealthcare.com)
In some cases, tandem repeats can serve as genetic markers to track inheritance in families. (genome.gov)
The sequence information provides a starting point from which the real research into the thousands of diseases that have a genetic basis can begin. (learner.org)
Students will gain knowledge in human genetic variability and DNA repeats, and skills in analyzing high-throughput sequencing data, algorithm design and testing, and database development. (bu.edu)

Variable numbers of tandem repeats (VNTR) or microsatellite markers, on the other hand, are codominant markers and therefore provide more information. (biomedcentral.com)
Non-homologous recombination NAHR, Mobile element insertion (MEI), variable number of simple tandem repeats (VNTR) non-homologous rearrangement. (blogspot.com)
This project will develop new algorithmic and statistical methods to permit detection of longer VNTR repeats and the use of longer read sequencing technologies. (bu.edu)
A 40-bp variable number of tandem repeats (VNTR) polymorphism exists in the 15th exon of DAT1 , the gene encoding the human dopamine transporter (DAT). (biomedcentral.com)
Though the VNTR resides in a region encoding the 3' untranslated region (UTR) and does not alter the protein's amino acid sequence, the prevalent 10-repeat variant has shown both linkage and association to Attention Deficit Hyperactivity Disorder (ADHD). (biomedcentral.com)
Though the VNTR resides in the 3'UTR and therefore does not affect the protein's amino acid sequence, regulatory factors such as mRNA stability and nuclear transport, and protein synthesis are potentially regulated by such variations [ 11 - 14 ]. (biomedcentral.com)
Despite its high frequency in the general population [ 7 ] and an absence of studies addressing possible effects of the VNTR on measures of DAT physiology and pharmacology, the 10-repeat DAT1 allele has become generally recognized as a "high risk" allele for ADHD. (biomedcentral.com)
Flp recombinase, the enzymatic basis of the system, is a Saccharomyces cerevisiae derived enzyme that utilizes a substrate Flp recombination target (FRT) sequence upstream of a gene of interest (GOI) to site-specifically insert the GOI into a target site in a host cell line, thereby providing a well-controlled approach to establishing the in vitro functional effect of the DAT1 VNTR polymorphism on the DAT [ 37 ]. (biomedcentral.com)

The process of DNA mismatch repair plays a prominent role in the formation of direct trinucleotide repeat expansions. (wikipedia.org)
Such repeat expansions underlie several neurological and developmental disorders in humans. (wikipedia.org)
Genome-wide sequencing as a first-tier screening test for short tandem repeat expansions. (cdc.gov)
Tandem repeat expansions are repeated DNA sequences that can cause unstable changes in proteins, and may be the cause of epilepsies in other patients as well (Fan & Chu, 2007). (defeatingepilepsy.org)

MToolBox: a highly automated pipeline for heteroplasmy annotation and prioritization analysis of human mitochondrial variants in high-throughput sequencing. (genomeweb.com)
those containing only the DAT1 coding region or the coding region flanked by a truncated 3' UTR resulted in greater DAT density than either of the naturalistic 9- and 10-repeat variants. (biomedcentral.com)

Unlocking the secondary gene-pool of barley with next-generation sequencing. (genomeweb.com)
We performed a whole gene sequencing of the entire FLG coding region using next-generation sequencing technology. (bvsalud.org)
Is it possible to move the goal-posts and say that a clinical "test" no longer revolves around the actual sequencing of a cancer gene, as in the case of BRCA1/2 screening, but is now more about the algorithm used to ask specific questions of what could be a lifetime stored data set? (blogspot.com)
The application uses various web services to gather gene sequence information, local algorithms for tandem repeats identification and similarity measures for gene clustering. (inderscience.com)

A chromosome-based draft sequence of the hexaploid bread wheat ( Triticum aestivum ) genome. (genomeweb.com)
The first tumours they sequenced had mutational phenotypes that went against a gradual model of tumour evolution, no mutations on some chromosomes but massively instable (chromothriptic) chromosome 15. (blogspot.com)
A tandem repeat is a sequence of two or more DNA bases that is repeated numerous times in a head-to-tail manner on a chromosome. (genome.gov)
One special type of plasmid used for genome sequencing is a bacterial artificial chromosome (BAC) , which can contain DNA fragments of about 150 kb. (learner.org)
Interestingly, my very first scientific work, my thesis, was devoted to cloning and sequencing the first fragment of a chromosome containing these alpha-like repeats of DNA centromeres. (vechnayamolodost.ru)

Comparative genomics using paired BAC-ends revealed several regions of conserved synteny across all the fish species analyzed in this study. (biomedcentral.com)
We think the assembly quality is comparable to traditional Sanger assembly, and can be used in annotation, comparative genomics, resequencing, and other analysis," he said. (genomeweb.com)

A tract of repetitive DNA in which a motif of a few base pairs is tandemly repeated numerous times (e.g. 5 to 50 times) is referred to as microsatellite DNA. (wikipedia.org)
The number of repeats at a certain microsatellite locus might vary greatly between people in a population because microsatellite DNA is highly variable. (vajiramandravi.com)
Tumour mutational burden, microsatellite instability, and actionable alterations in metastatic colorectal cancer: Next-generation sequencing results of TRIBE2 study. (cdc.gov)

In particular, our interests lie in two classes of variations known as structural variations and tandem repeats. (ccmb.res.in)
And structural variation hotspots in the human genome are formed by single processes at each hotspot, that is the underlying sequence drives the kind of SV seen in a hotspot. (blogspot.com)

However, the lack of a reference genome sequence hampers research progress for both academic and applied purposes. (biomedcentral.com)

As with other mitochondrial carrier family proteins, the ornithine carrier is composed of 300 amino acids that constitute 3 repeated motifs of approximately 100 amino acids each. (medscape.com)
The transporter was identified by probing a mammalian-expressed sequence tag database with 2 fungal mitochondrial ornithine carrier protein sequences. (medscape.com)

Genome sequencing of normal cells reveals developmental lineages and mutational processes. (genomeweb.com)

2022. Repeat Detector: versatile sizing of expanded tandem repeats and identification of interrupted alleles from targeted DNA sequencing . (cardiff.ac.uk)

A highly accurate statistical method that computes the abundance of species in DNA sequences from a metagenomics sample. (gwdg.de)
Advance the use of genomics and metagenomics for detecting fungal pathogens and antifungal drug resistance. (cdc.gov)

Canu is a fork of the Celera Assembler designed for high-noise single-molecule sequencing (such as the PacBio RSII or Oxford Nanopore MinION). (gwdg.de)

Evgeny Rogaev is a Doctor of Biological Sciences, Corresponding Member of the Russian Academy of Sciences, Head of the Laboratory of Evolutionary Genomics at the Institute of General Genetics of the Russian Academy of Sciences, Professor at the University of Massachusetts Medical School, Director of the Scientific Center for Genetics and Life Sciences at Sirius University. (vechnayamolodost.ru)

The Marmoset Genome Sequencing and Analysis Consortium. (genomeweb.com)
International Wheat Genome Sequencing Consortium (IWGSC). (genomeweb.com)
The panda project "shows the power of high-throughput sequencing and the use of shotgun combined with long paired-end reads," said Kjetill Jakobsen, leader of the consortium that recently sequenced the cod genome with 454 technology and a professor of biology at the Centre for Ecological and Evolutionary Synthesis at the University of Oslo. (genomeweb.com)
We are rapidly acquiring new genomics tools for D. magna such as the genome project which all can be found in Daphnia Genomics Consortium webpage [ 9 ]. (biomedcentral.com)

Flanking (or terminal) repeats (terminal repeat sequences) are sequences that are repeated on both ends of a sequence, for example, the long terminal repeats (LTRs) on retroviruses. (wikipedia.org)
Furthermore a group of non- autonomous elements has been identified, featured by tandem repeated sequences between the LTRs and apparently unrelated to any known Culex retrotransposon family. (uniba.it)

Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity. (genomeweb.com)
In the present study, we used genotyping-by-sequencing and genome-wide association to identify marker loci associated with biomass yield under drought in the field in a panel of diverse germplasm of alfalfa. (usda.gov)

In order to enrich the genomic tools already available in this species and provide further insight on the complexity of its genome, we sequenced a large number of rainbow trout BAC-end sequences (BES) and characterized their contents. (biomedcentral.com)
In contrast, marine bony fish harbor more tandem repeats than freshwater species. (syr.edu)
However, due to the restriction of the limited sequenced species, further analysis needs to be done to alleviate the phylogenetic biases. (syr.edu)
Dulbecco also argued that such a project should be "an international undertaking, because the sequence of the human DNA is the reality of the species, and everything that happens in the world depends upon those sequences. (learner.org)
Though the species of this group show a high degree of karyotypic similarity, D. soaresi was unique in presenting large blocks of het- ITSs (heterochromatic internal telomeric sequences) in the majority of the centromeres. (pensoft.net)

Sr26 and Sr61 are each validated by transgenic complementation using endogenous and/or heterologous promoter sequences. (nature.com)

In other words, the direct repeats are nucleotide sequences present in multiple copies in the genome. (wikipedia.org)
The nucleotide sequence written in bold characters signifies the repeated sequence. (wikipedia.org)
single‐nucleotide polymorphisms (SNPs) or insertions/deletions (indel) polymorphisms in the nucleotide sequence of that fragment, either within the repetitive array or in the flanking regions (FR), remain undetected by length assessment alone. (cd-genomics.com)
To overcome such errors, information about the nucleotide sequence of each allele is needed. (cd-genomics.com)
Finally, automated sequencing machines determine the order of each nucleotide of the many small fragments. (learner.org)

Sr60 is an exception that encodes a tandem kinase protein 10 . (nature.com)
These motifs contain 2 hydrophobic alpha-helical segments connected by an extensive hydrophilic sequence, resulting in 6 transmembrane portions of the protein. (medscape.com)

The study is one of the first in which researchers sequenced and de novo assembled a large mammalian genome using only short-read technology. (genomeweb.com)

The implementation of proprietary algorithms that are highly robust to fluctuations in sequencing coverage guarantee that what is normally considered average sequencing yield is more than enough to achieve variant calling at high sensitivity and precision. (sequegenics.com)

Reading the nucleotides from two ends of a DNA fragment is called paired-end tag (PET) sequencing. (biomedcentral.com)
In 2001 two rival teams jointly announced the completion of a draft sequence of the entire human genome, consisting of more than three billion nucleotides. (learner.org)

Stepwise threshold clustering: a new method for genotyping MHC loci using next-generation sequencing technology. (genomeweb.com)
This method can genotype plenty of SSR loci in hundreds of samples with highly accurate results, due to the substantial coverage afforded by high throughput sequencing, which also greatly reduces the cost and time of genotyping, and the comparison between samples can be directly based on the base sequence. (cd-genomics.com)

Approximately 55% of the BES reads (97,846) had more than 100 base pairs of contiguous non-repetitive sequences. (biomedcentral.com)

AAV type 2 wild-type and vector-mediated genomic integration profiles in human diploid fibroblasts analyzed by 3rd generation PacBio DNA sequencing. (genomeweb.com)

When we use modern sequencing methods to read short sequences (short reading), such sections are very difficult to orient. (vechnayamolodost.ru)

These results integrate the existing data on the genomics of an important disease vector. (uniba.it)
This eliminates the need for additional sequencing data to be produced. (sequegenics.com)
Data management and analysis are critical parts of the process, as these sequencing machines generate vast amounts of data. (learner.org)
The lab has developed an analysis tool, VNTRseek, to identify VNTRs, using high-throughput sequencing data, but it is limited to those TRs that ﬁt within a sequencing read. (bu.edu)
This project involves the development of statistical tools and software for jointly analyzing microbial and host data from sequencing experiments, in order to determine community content, microbe-microbe interactions, and host-microbe relationships. (bu.edu)
Microbial DNA sequence data will be collected from soils obtained through a national sampling initiative - the National Ecological Observatory Network (NEON). (bu.edu)

The genomic sequence analysis recently performed by Arensburger et al. (uniba.it)
Identification of a salmonellosis outbreak by means of molecu- variable number tandem repeat analysis type in Australia, 2014. (who.int)
Some comments and analysis from the exciting and fast moving world of Genomics. (blogspot.com)
Moreover, computer software for sequence analysis was just being developed. (learner.org)
What exactly from the human genome have you sequenced?The role of our group's employees is to participate in the analysis of centromeric alpha-like DNA repeats. (vechnayamolodost.ru)
We are interested in the analysis and modeling of the three-dimensional chromatin structure from high-throughput sequencing experiments. (ucsd.edu)

Editorial: Genomics and Epigenomics of Cancer Immunotherapy: Challenges and Clinical Implications. (cdc.gov)
The future of long-read sequencing has the potential to transform biological sciences, as well as clinical services, according to Miller. (brotmanbatyinstitute.org)

Long-range PCR in next-generation sequencing: comparison of six enzymes and evaluation on the MiSeq sequencer. (genomeweb.com)

There are several types of repeated sequences : Interspersed (or dispersed) DNA repeats (interspersed repetitive sequences) are copies of transposable elements interspersed throughout the genome. (wikipedia.org)

The focus is understanding the occurrence and functional effects of tandem repeats (TRs), and especially, those with variable copy number, also known as variable number of tandem repeats (VNTRs). (bu.edu)

The first rainbow trout repeat elements database (INRA RT rep1.0) containing 735 putative repeat elements was developed, and identified almost 59.5% of the BES database in base-pairs as repetitive sequence. (biomedcentral.com)

Most of the unread genome just belonged to centromeric regions, these are special sections of chromosomes that are necessary for cell division, and they usually consist of tandem repeating DNA sequence units. (vechnayamolodost.ru)

Quantitative full-length sequencing of the HIV-1 transcriptome in primary cell derived resting CD4+ T-cells and T-cell subsets. (brotmanbatyinstitute.org)

Centromeres in all chromosomes were considered homogeneous, consisting of identical repeats. (vechnayamolodost.ru)

GMCK-RD represents a long-term collaborative initiative between Karolinska University Hospital and Science for Life Laboratory to establish advanced, genomics-based diagnostics in the Stockholm healthcare setting. (scilifelab.se)

Many methods designed for tandem repeat detection on reference sequence. (biomedcentral.com)

Their sequences now provide perfect markers and diagnostic tools for marker-assisted breeding. (nature.com)

We also study how the same DNA sequence can give rise to different phenotypes, as observed in various cell types of a single organism. (ccmb.res.in)

However, William Davidson, a professor of molecular biology and biochemistry at Simon Fraser University who is involved in the project to sequence the Atlantic salmon genome, questioned a section in the paper's supplementary material that explains that gaps with tandem repeats that could not be resolved were filled in with Ns and that the contig N50 size grew from 1,483 bp to 39.9 Kb. (genomeweb.com)

These repeating units, which are typically 1-6 base pairs in length, are repeated in tandem, and the amount of repetitions varies between individuals. (vajiramandravi.com)

In clone-based sequencing (also known as hierarchical shotgun sequencing) the first step is mapping. (learner.org)

Interactive graphical genome browsers are essential tools in genomics, but they do not contain all the recent genome assemblies. (biomedcentral.com)

Assessing the impact of water treatment on bacterial biofilms in drinking water distribution systems using high-throughput DNA sequencing. (genomeweb.com)

The SOAPdenovo algorithm was key to the assembly's accuracy, lead author Jun Wang told In Sequence in an e-mail: "The different insert sizes [for] paired-end sequencing is a key factor here," he said. (genomeweb.com)

The discovery of specific repeat elements will facilitate analyses of sequence content (e.g. for SNPs discovery and for transcriptome characterization) and future genome sequence assemblies. (biomedcentral.com)
But as can be seen from these numbers, most sequenced assemblies are still not yet available in any genome browser. (biomedcentral.com)

Mature mouse ApoH shares 76% and 42% aa sequence identity with human and rat ApoH, respectively. (rndsystems.com)
Human Genomics vol. 16 , n° 1 , dir. (mnhn.fr)
In 1986 Nobel laureate Renato Dulbecco laid down the gauntlet to the scientific community to sequence the complete human genome. (learner.org)
Like the conquest of space, sequencing the human genome required the development of wholly new technologies. (learner.org)
The capstone, of course, was the completion of the human genome sequence. (learner.org)
One major surprise emerged from the sequencing of the human genome. (learner.org)
Hi, Using the interval file which you used to fetch fasta sequences, you'll be able to fetch human-chimp alignments. (usegalaxy.org)
The relationship between genome characteristics and several human diseases has been a central research goal in genomics. (inderscience.com)
According to an approximate estimate, the version of the human nuclear genome, which has been constantly replenished and improved since 2001, did not contain about 8% of the genomic DNA sequence. (vechnayamolodost.ru)

While the genome sequence was already transformative at the time, the past 25 years of progress have substantially increased its impact on TB taxonomy, drug discovery, resistance mechanisms, epidemiology, vaccine development, and pathogenesis. (jci.org)

Chemicals and Drugs1

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Phenomena and Processes12

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