Genomic dna or rna. Medical search. Frequent questions

DNA Genotek's sample collection devices and nucleic acid stabilization chemistries are protected by issued and pending patents in numerous countries around the world. (dnagenotek.com)
FormaPure XL Total by Beckman Coulter is a single-chemistry extraction kit to isolate total nucleic acid (RNA and DNA) from FFPE tissues. (labcyte.com)
For viruses with an RNA genome, the nucleic acid must enter the nucleus (perhaps accidentally for viruses without a nuclear phase) and be converted to a DNA copy by reverse transcriptase encoded by endogenous retroviruses. (virology.ws)
The delivered nucleic acid extraction kits can deliver up to 2 million laboratory reactions and are used in diagnostic devices called 'automated extraction machines' to extract genomic nucleic acid DNA and RNA of bacteria, viruses and parasites for PCR-based detection from a wide range of samples. (who.int)

The genome of an organism (encoded by the genomic DNA) is the (biological) information of heredity which is passed from one generation of organism to the next. (wikipedia.org)
That genome is transcribed to produce various RNAs, which are necessary for the function of the organism. (wikipedia.org)
Aprataxin resolves adenylated RNA-DNA junctions to maintain genome integrity. (medlineplus.gov)
The genome, or genetic material, of an organism is made up of a unique DNA or RNA sequence. (cdc.gov)
All subtracks use coordinates provided by RefSeq, except for the UCSC RefSeq track, which UCSC produces by realigning the RefSeq RNAs to the genome. (ucsc.edu)
They were predicted based on protein, cDNA, EST and RNA-seq alignments to the genome assembly by the NCBI Gnomon prediction software. (ucsc.edu)
RefSeq Alignments - alignments of RefSeq RNAs to the zebrafish genome provided by the RefSeq group, following the display conventions for PSL tracks . (ucsc.edu)
UCSC RefSeq - annotations generated from UCSC's realignment of RNAs with NM and NR accessions to the zebrafish genome. (ucsc.edu)
To support comprehensive analysis of a genome/exome from one sample, SPRI paramagnetic bead-based technology enables rapid and highly efficient extraction of RNA and genomic, plasmid and mitochondrial DNA. (labcyte.com)
During the replication of retroviruses, a double-stranded DNA copy of the viral RNA genome is synthesized by reverse transcription and integrated into the genomes of the infected cell. (virology.ws)
The first non-retroviral endogenous virus described was bornavirus, a virus with a negative-stranded RNA genome. (virology.ws)
The genome of circoviruses are composed of single-stranded DNA, while those of parvoviruses are linear single-stranded DNAs with base-paired ends (figure). (virology.ws)
The Streptococcus pyogenes Cas9 (SpCas9) nuclease can be efficiently targeted to genomic loci by means of singleguide RNAs (sgRNAs) to enable genome editing 1 - 10 . (cdc.gov)
Positive-sense RNA viruses possess a single-stranded RNA genome that can serve as messenger RNA (mRNA) that can be directly translated to produce an amino acid sequence. (msdmanuals.com)
Negative-sense RNA viruses possess a single-stranded negative-sense genome that first must synthesize a complementary positive-sense antigenome, which is then used to make genomic negative-sense RNA. (msdmanuals.com)
Retroviruses use reverse transcription to create a double-stranded DNA copy (a provirus) of their RNA genome, which is inserted into the genome of their host cell. (msdmanuals.com)
the genome of RNA viruses ranges from 3.5 kilobases (some retroviruses) to 27 kilobases (some reoviruses), and the genome of DNA viruses ranges from 5 kilobases (some parvoviruses) to 280 kilobases (some poxviruses). (msdmanuals.com)
We use a combination of state-of-the-art genomic methods, including whole genome, RNA and Exome sequencing as well as single-cell DNA and RNA-sequencing and leukemia mouse models in our work. (lu.se)

Precursor mRNA (pre-mRNA) is transcribed by RNA polymerase II in the nucleus. (wikipedia.org)
These types are transcribed by RNA polymerase I and RNA polymerase III, respectively, and are essential for protein synthesis. (wikipedia.org)
However 5s rRNA is the only rRNA which is transcribed by RNA Polymerase III. (wikipedia.org)
In a single tube, RNA is first converted to cDNA by a reverse transcriptase, and then a DNA-dependent DNA polymerase amplifies the cDNA, enabling quantitation via qPCR. (neb.com)
In the Luna Probe One-Step RT-qPCR Kit (No ROX), Hot Start Taq DNA Polymerase is combined with a novel WarmStart-activated reverse transcriptase, allowing dual control of enzyme activity via reversible, aptamer-based inhibition. (neb.com)
The Luna Probe One-Step RT-qPCR Kit (No ROX) is supplied at 2X concentration and contains Hot-Start Taq DNA Polymerase, dNTPs, and all required buffer components. (neb.com)
HBV replication is initiated by the binding of polymerase (P) to epsilon (ε), a 61 nucleotide (nt) cis -acting regulatory stem-loop RNA located at the 5′-end of the pregenomic RNA (pgRNA). (nist.gov)
All organisms-bacteria, archaea, and eukaryotes-have a transcription initiation factor that contains a structural module that binds within the RNA polymerase (RNAP) active-center cleft and interacts with template-strand single-stranded DNA (ssDNA) in the immediate vicinity of the RNAP active center. (osti.gov)
A DNA polymerase with reverse transcriptase activity: Genomic replication takes place through an intermediate RNA known as pregenomic RNA. (medscape.com)

G-quadruplex (G4) DNA, an alternate structure formed by Hoogsteen hydrogen bonds between guanines in G-rich sequences, threatens genomic stability by perturbing normal DNA transactions including replication, repair, and transcription. (nih.gov)
We find that this type of non-canonical fork convergence in fission yeast is prone to trigger deletions between repetitive DNA sequences via a mechanism we call Inter-Fork Strand Annealing (IFSA) that depends on the recombination proteins Rad52, Exo1 and Mus81, and is countered by the FANCM-related DNA helicase Fml1. (elifesciences.org)
The NCBI RefSeq Genes composite track shows zebrafish protein-coding and non-protein-coding genes taken from the NCBI RNA reference sequences collection (RefSeq). (ucsc.edu)
With the exception of retroviruses, these endogenous viral sequences have no role in viral replication - they are accidentally integrated into host DNA. (virology.ws)
It is possible that some of the endogenous viral sequences are copied into RNA, or translated into protein, and could have consequences for the host. (virology.ws)
Sequences from ancestral single-stranded DNA viruses in vertebrate genomes: the parvoviridae and circoviridae are more than 40 to 50 million years old. (virology.ws)
The Luna Probe One-Step RT-qPCR Kit (No ROX) is optimized for real-time quantitation of target RNA sequences using hydrolysis probes. (neb.com)
We performed northern blot analyses for the guide RNA truncations and found increased levels of expression for the longer tracrRNA sequences, suggesting that improved target cleavage was at least partially due to higher sgRNA expression or stability ( Fig. 1c ). (cdc.gov)

pre-mRNA is then processed by splicing to remove introns, leaving the exons in the mature messenger RNA (mRNA). (wikipedia.org)
Both vaccines use laboratory-produced messenger RNA (mRNA) as the active ingredient. (cdc.gov)

Extensive quality control procedures ensure high quality genomic DNA. (3hbiomedical.com)
This app could also motivate laboratories to perform diagnostic tests to provide high-quality genomic data. (jmir.org)

RNA (total, poly A+ and miRNA), chromatin immunoprecipitated DNA (ChIP-Seq) and DNA (genomic and amplicon-derived). (utmb.edu)

Different parts of the aprataxin protein allow the protein to interact with other DNA repair proteins to make repairs. (medlineplus.gov)
Proteins/genes with a putative catabolic role and bacterium adaptation mechanisms during OPP degradation were identified via genomic and proteomic analysis. (nature.com)
These tasks can help with understanding the dynamics of how DNA is translated into RNA and proteins, unlocking new clinical applications. (nvidia.com)
Caris molecular profiling performs thorough molecular testing on DNA, RNA and proteins to identify the biomarkers driving a patient's tumor, and to compare the biomarkers with data from clinical studies around the world. (carislifesciences.com)
Once the provirus is integrated into the host cell DNA, it is transcribed using typical cellular mechanisms to produce viral proteins and genetic material. (msdmanuals.com)

Hepadnaviruses encode a reverse transcriptase which produces the genomic DNA from an RNA template. (virology.ws)
The Luna WarmStart RT Enzyme Mix is supplied at 20X concentration and contains Luna WarmStart Reverse Transcriptase as well as Murine RNase Inhibitor to aid in preventing RNA degradation (see also template preparation in product manual). (neb.com)

It does not become part of the cell or affect a person's genes or DNA. (cdc.gov)
One technique that is garnering wide attention in this realm is the DNA array, in which a number of different genes from an individual can be processed to look at certain genotypes. (medscape.com)
For example, in the hereditary cancer syndromes familial adenomatous polyposis or hereditary nonpolyposis colorectal cancer, mutations have been discovered in the APC gene and DNA mismatch repair genes. (medscape.com)

FANCJ belongs to a conserved iron-sulfur (Fe S) cluster family of helicases important for genomic stability including XPD (nucleotide excision repair), DDX11 (sister chromatid cohesion), and RTEL (telomere metabolism), genetically linked to xeroderma pigmentosum/Cockayne syndrome, Warsaw breakage syndrome, and dyskeratosis congenita, respectively. (nih.gov)
The library is loaded into a sequencer, which will identify the nucleotide bases in the DNA fragments. (cdc.gov)
The QIAamp DNA FFPE Tissue Kit purifies DNA that can be used in a wide range of downstream applications, such as single nucleotide polymorphism (SNP) and short-tandem repeat (STR) genotyping and pharmacogenomic research. (qiagen.com)
sgRNAs with +67 or +85 nucleotide (nt) tracrRNA tails mediated DNA cleavage at all target sites tested, with up to fivefold higher levels of indels than the corresponding crRNA-tracrRNA duplexes ( Fig. 1b and Supplementary Fig. 1a ). (cdc.gov)

Other types of RNA include ribosomal RNA (rRNA) and transfer RNA (tRNA). (wikipedia.org)
ribosomal RNA identification of the isolates showed high score similarity with Pseudomonas spp. (lu.se)
Some of the enzymes which generate aromatic radicals that break down most prominent bacterial strains found were isolated and tax- the complex linkages present in lignin to compounds of lower onomically identified using 16S ribosomal RNA (rRNA) se- molecular weight. (lu.se)

DNA Genotek Inc., a subsidiary of OraSure Technologies, Inc. (NASDAQ: OSUR), focuses on providing high-quality biological sample collection products and end-to-end services for human genomics, microbiome and infectious disease applications. (dnagenotek.com)
The joint team of researchers showed that large language models (LLMs) trained on genomics can generalize across a plethora of genomic tasks. (nvidia.com)

I am seeing genomic DNA in my preps when using the Monarch Total RNA Miniprep Kit What could be the problem? (neb.com)
FAQ: I am seeing genomic DNA in my preps when using the Monarch Total RNA Miniprep Kit. (neb.com)
The Monarch Total RNA Miniprep Kit employs both a specific column to capture gDNA ( NEB #T2017 ) and a separate on-column enzymatic DNase I treatment. (neb.com)
Total RNA and DNA from homogenized mosquito pools and tissue samples of brain, liver, lung, and heart from bats and birds were extracted. (cdc.gov)

The Wizard® Genomic DNA Purification Kit provides a simple, solution-based method for isolation of DNA from white blood cells, tissue culture cells, animal tissue, plant tissue, yeast and Gram-positive and Gram-negative bacteria. (selectscience.net)
The QIAamp DNA FFPE Tissue Kit is intended for molecular biology applications. (qiagen.com)
The QIAamp DNA FFPE Tissue Kit is specially designed for purifying DNA from formalin-fixed, paraffin-embedded tissue sections. (qiagen.com)
The kit uses special lysis conditions to release DNA from tissue sections and to overcome inhibitory effects caused by formalin crosslinking of nucleic acids. (qiagen.com)
Purification of DNA using the QIAamp DNA FFPE Tissue Kit can be automated on the QIAcube Connect . (qiagen.com)
The QIAamp DNA FFPE Tissue Kit uses well-established QIAamp MinElute technology for purification of genomic and mitochondrial DNA from small sample volumes or sizes. (qiagen.com)
Specially optimized lysis conditions allow genomic DNA to be efficiently purified from FFPE tissue sections without the need for overnight incubation. (qiagen.com)
After sample lysis, the simple QIAamp DNA FFPE Tissue procedure, which is highly suited for simultaneous processing of multiple samples, yields pure DNA in less than 30 minutes. (qiagen.com)
PCR analysis of DNA purified from FFPE tissue samples. (qiagen.com)
Genomic DNA was purified from different FFPE tissue samples using the QIAamp DNA FFPE Tissue Kit. (qiagen.com)
The FormaPure XL Total extraction and purification kit uses SPRI technology to isolate RNA and DNA from formalin-fixed, paraffin-embedded (FFPE) tissue, without the use of xylene. (labcyte.com)
BioChain's tissue genomic DNAs are isolated from a wide variety of tissues using a proprietary modified guanidine thiocyanate technique. (biochain.com)
Levels of gene expression are measured using a preparation of fluorescently labeled tissue RNA (copies of DNA), together with reference RNA labeled with a different fluorochrome, hybridized onto the slides. (lu.se)

Design and analysis methods for DNA and RNA sequence variation studies. (mayo.edu)
These include DNA sequence variation, gene expression, proteomics and metabolomics. (mayo.edu)
We find that SpCas9 tolerates mismatches between guide RNA and target DNA at different positions in a sequence-dependent manner, sensitive to the number, position and distribution of mismatches. (cdc.gov)
Following crRNA and tracrRNA hybridization, SpCas9 is targeted to genomic loci matching a 20-nt guide sequence within the crRNA, immediately upstream of a required 5′-NGG protospacer adjacent motif (PAM) 11 . (cdc.gov)
Areas that will be covered include: sequence databases, pairwise and multiple sequence alignment, searches in sequence databases, amino acid substitution matrices, secondary structure, prediction of RNA and polypeptides, and models for protein classification. (lu.se)

Determining the order of bases-"genomic sequencing" or simply, "sequencing"-is a core AMD technology. (cdc.gov)
The DNA or RNA to be sequenced must be specially prepared before it can be put into the sequencing machine. (cdc.gov)
By 2003, 99% of the chemical base pairs that make up human DNA had been sequenced to within 99.99% accuracy (with the sequencing reported to have reached 100% by 2021). (medscape.com)
Contact us about our methodology and software for use in studies on family-based genetic epidemiology, genetic association of common diseases, and DNA and RNA sequencing. (mayo.edu)
The company, which has about 15 employees but shares additional staff members and resources with its parent firm, currently offers a variety of genomic services, including next-generation sequencing on the Roche/454 GS FLX and GS Junior platforms. (genomeweb.com)

Genomic deoxyribonucleic acid (abbreviated as gDNA) is chromosomal DNA, in contrast to extra-chromosomal DNAs like plasmids. (wikipedia.org)

Genomic DNA methylation study. (3hbiomedical.com)
DMRs show continuous gain or loss of methylation during differentiation, and the overall change in DNA methylation correlates inversely with gene expression at key loci. (lu.se)
In particular, certain types of ALKBH enzymes are dioxygenases that directly reverse DNA methylation damage via transfer of a methyl group from the DNA adduct onto α-ketoglutarate and release of metabolic products including succinate and formaldehyde. (frontiersin.org)
We also show that SpCas9-mediated cleavage is unaffected by DNA methylation and that the dosage of SpCas9 and sgRNA can be titrated to minimize off-target modification. (cdc.gov)

The principle is based on the use of nonin- the PCR techniques capable of amplifying any adventi- fectious but replication-competent genomic RNA. (cdc.gov)
Problems that arise during DNA replication can drive genomic alterations that are instrumental in the development of cancers and many human genetic disorders. (elifesciences.org)
Eukaryotic DNA replication initiates at multiple origin sites along each chromosome and terminates when replication forks (RFs) from adjacent origins converge. (elifesciences.org)
This so-called recombination-dependent replication (RDR) helps ensure that DNA is fully replicated prior to sister chromatid segregation, thereby avoiding mitotic catastrophes. (elifesciences.org)
Taken together, our work strongly implicates RNA dynamics as an integral feature that governs HBV replication. (nist.gov)
Some viruses have an outer envelope consisting of protein and lipid, surrounding a protein capsid complex with genomic RNA or DNA and sometimes enzymes needed for the first steps of viral replication. (msdmanuals.com)
Certain single-strand, (+) sense RNA viruses termed retroviruses use a very different method of replication. (msdmanuals.com)

Human PBMC Genomic DNA was prepared from purified healthy human peripheral blood mononuclear cells (PBMCs) of single donor. (3hbiomedical.com)
Each organ genomic DNA is from a single donor. (biochain.com)

Now in its second edition, Applying Genomic and Proteomic Microarray Technology in Drug Discovery highlights, describes, and evaluates current scientific research using microarray technology in genomic and proteomic applications. (routledge.com)

Pair-wise comparison of three experimental conditions was obtained either with two labeled cDNA samples co-hybridized to the same array, or by employing Shewanella genomic DNA as a standard reference. (biomedcentral.com)

In what follows we limit ourselves to the analysis of gene expression measurements obtained using microarrays with small spots of DNA fixed to glass slides. (lu.se)

BioChain's Genomic DNAs are available from human tumor tissues. (biochain.com)

To elucidate the role of FANCJ in genomic stability, its molecular functions in G4 metabolism were examined. (nih.gov)
The discovery of the structure of DNA by Francis Crick and James Watson in the early 1950s ushered in a new era in molecular biologic science. (medscape.com)
Note that DNA isolated from FFPE samples is usually of lower molecular weight than DNA from fresh or frozen samples. (qiagen.com)
Our comprehensive molecular profiling approach precisely analyzes DNA, RNA, and protein biomarkers, revealing the highest quality molecular blueprint for evidence-based selection of the most appropriate cancer therapy. (carislifesciences.com)

Wizard® Genomic DNA Purification Kit from Promega Corp. (selectscience.net)
Wizard® Genomic DNA Purification Kit Fea. (selectscience.net)

Genomic Instability. (nih.gov)
Here, we tested whether ALKBH6 plays a significant role in preventing alkylating DNA damage and decreasing genomic instability in pancreatic cancer cells. (frontiersin.org)

Rapid, sensitive and precise probe-based qPCR detection and quantitation of target RNA targets. (neb.com)
One-Step RT-qPCR provides a convenient and powerful method for RNA detection and quantitation. (neb.com)

Moreover, these motions occur in mostly conserved nucleotides from structural regions (i.e., priming loop, pseudo-triloop, and U43 bulge) that biochemical and mutational studies have shown to be essential for P binding, protein-priming, pgRNA packaging, and DNA synthesis. (nist.gov)

One kind of such references is common RNA pools assembled from a number of different cell lines, tissues and conditions. (biomedcentral.com)

2 - 4 Expression profiling on a genomic scale led to the classification of the intrinsic subtypes of breast cancer, thus allowing for the prediction of disease progression and patient stratification. (dovepress.com)

DNA viruses typically replicate in the host cell nucleus, and RNA viruses typically replicate in the cytoplasm. (msdmanuals.com)

Genomic DNA contamination is very common in RNA preps. (neb.com)
Contamination of RNA, polysaccharides and proteoglycans has been effectively eliminated. (biochain.com)

These findings suggest FANCJ is a specialized Fe-S cluster helicase that preserves chromosomal stability by unwinding unimolecular G4 DNA likely to form in transiently unwound single-stranded genomic regions. (nih.gov)
Based on our findings, we propose that IFSA is a potential threat to genomic stability in eukaryotes. (elifesciences.org)

DNA or RNA has become an indispensable tool for the VACCINES diagnosis and surveillance of viral disease. (cdc.gov)
In all cases, recombination could lead to integration of viral DNA into the host chromosome. (virology.ws)

100 predicted genomic off-target loci in 293T and 293FT cells. (cdc.gov)

Our high quality reagents are available for every workflow, including popular DNA assembly methods such as NEBuilder ® HiFi DNA Assembly and NEBridge ® Golden Gate Assembly . (neb.com)

either DNA or RNA viruses may have single or double strands of genetic material. (msdmanuals.com)

To implement clinical NGS applications, health care providers operate their own NGS laboratories or request genomic tests to external laboratories. (jmir.org)
Using genomic DNA as common reference in microarray experiments has recently been tested by different laboratories. (biomedcentral.com)
What genomic services does IMGM Laboratories provide? (genomeweb.com)

At the site of the damage, aprataxin modifies the broken ends of the DNA strands so they can be joined back together correctly. (medlineplus.gov)
Strands of DNA or RNA are first extracted from the bacteria, virus, or other pathogen. (cdc.gov)
Others identify bases by monitoring changes to an electrical current as the DNA strands pass through tiny holes. (cdc.gov)

The BRCA1-associated FANCJ helicase is among those helicases able to unwind G4 DNA in vitro, and FANCJ mutations are associated with breast cancer and linked to Fanconi anemia. (nih.gov)
The G4-specific ligands Phen-DC3 or Phen-DC6 inhibited FANCJ helicase on unimolecular G4 ∼1000-fold better than bi- or tetramolecular G4 DNA. (nih.gov)

The G4 ligand telomestatin induced DNA damage in human cells deficient in FANCJ but not DDX11 or XPD. (nih.gov)
In particular, the loss of ALKBH6 in human pancreatic cancer cells increases alkylating agent-induced DNA damage and significantly decreases cell survival. (frontiersin.org)
The extremely low 5-year overall survival of patients is, in part, due to pancreatic cancer cells having several mechanisms of resistance to different chemotherapeutic treatments, one of which is their capacity to efficiently repair alkylating agent-induced DNA damage. (frontiersin.org)

Using the SURVEYOR nuclease assay 13 , we assessed the ability of each Cas9-sgRNA complex to generate indels in human embryonic kidney (HEK) 293FT cells through the induction of DNA doublestranded breaks (DSBs) and subsequent nonhomologous end joining (NHEJ) DNA damage repair (Online Methods). (cdc.gov)

However, this transcription initiation-factor structural module occupies the path of nascent RNA and thus presumably must be displaced before or during initial transcription. (osti.gov)
The structures reveal that-for both the primary σ-factor and extracytoplasmic (ECF) σ-factors, and for both 5'-triphosphate RNA and 5'-hydroxy RNA-the "σ-finger" is displaced in stepwise fashion, progressively folding back upon itself, driven by collision with the RNA 5'-end, upon extension of nascent RNA from ~5 nt to ~10 nt. (osti.gov)

Genomic analysis identified two orthologous operons encoding the ortho -cleavage of benzoic acid (BA) ( ben/cat ). (nature.com)
NIAGADS along with other NIA approved sites will make these Genomic Data and Associated Phenotypic Data available to qualified investigators in the scientific community for secondary analysis in accordance with standards established by the NIA. (nih.gov)
For RNA-seq analysis, we advise using NCBI aligned tables like RefSeq All or RefSeq Curated. (ucsc.edu)
This work could serve as a guideline for microarray data analysis using genomic DNA as a standard reference. (biomedcentral.com)
Random Amplified Polymorphic DNA (RAPD) analysis was carried out to study genomic changes using 10 different random primers. (cdc.gov)
No significant genomic changes were observed by RAPD analysis. (cdc.gov)
This FOA solicits applications for a Processing Genomic Data Center that will be a part of the Genomic Data Analysis Network. (nih.gov)
Genomic analysis revealed several unique amino acid substitutions among the polyprotein gene. (cdc.gov)

In this paper, we report four sets of crystal structures of bacterial initially transcribing complexes that demonstrate and define details of stepwise, RNA-extension-driven displacement of the "σ-finger" of the bacterial transcription initiation factor σ. (osti.gov)
Because RNA transcription does not involve the same error-checking mechanisms as DNA transcription, RNA viruses, particularly retroviruses, are particularly prone to mutation. (msdmanuals.com)
Extracted samples were analyzed for the presence of flavavirus RNA by using a modified pan-flavavirus reverse transcription PCR. (cdc.gov)

This honor has now been extended to other RNA viruses, and to circoviruses and parvoviruses, which possess single-stranded DNA genomes. (virology.ws)
Single-strand RNA viruses are further divided into those with (+) sense and (-) sense RNA. (msdmanuals.com)

For the legitimacy of clinical NGS genomic testing, quality information from the process of producing genomic data should be included within the results. (jmir.org)
The goal of this study was to develop a Fast Healthcare Interoperability Resources (FHIR)-based web app, NGS Quality Reporting (NGS-QR), to report and manage the quality of the information obtained from clinical NGS genomic tests. (jmir.org)
We defined data elements for the exchange of quality information from clinical NGS genomic tests, and profiled a FHIR genomic resource to enable information exchange in a standardized format. (jmir.org)
This study successfully demonstrated how quality information of clinical NGS genomic testing can be exchanged in a standardized format. (jmir.org)
As the demand for NGS genomic testing in clinical settings increases and genomic data accumulate, quality information can be used as reference material to improve the quality of testing. (jmir.org)

Importantly, alkylating agents induce DNA damage at different genomic sites, which subsequently leads to lethal and/or mutagenic DNA base lesions. (frontiersin.org)

Probe-based qPCR/RT-qPCR monitors an increase in fluorescence upon 5´ → 3´ exonuclease cleavage of a quenched, target-specific probe to measure DNA amplification at each cycle of a PCR. (neb.com)

FANCJ efficiently unwound in a kinetic and ATPase-dependent manner entropically favored unimolecular G4 DNA, whereas other Fe-S helicases tested did not. (nih.gov)

DNA Source: Anonymous donated human peripheral blood of a healthy adult. (3hbiomedical.com)

How are non-retroviral genomes integrated into the host DNA? (virology.ws)
Endogenous non-retroviral RNA virus elements in mammalian genomes. (virology.ws)

The concentration ofgenomic DNA is determined by Qubit dsDNA BR Assay. (3hbiomedical.com)

Chloroplast DNA typical of jack pine. (researchgate.net)

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