• A genomic island (GI) is part of a genome that has evidence of horizontal origins. (wikipedia.org)
  • Sequence based methods depend on the naturally occurring variation that exists between the genome sequence composition of different species. (wikipedia.org)
  • A phenomenon that has recently come to light via metagenomic studies is the prominence of phages with genomes that are much larger than the average size of ~55 kilobases (kb) predicted based on current genome databases 2 . (nature.com)
  • While we have seen a tremendous increase in knowledge about the diversity, genome composition and metabolic capabilities of microbial species living in the ocean, we still lack insights about how these communities work at a systems level. (fems-microbiology.org)
  • This will briefly summarize the major aspects of metagenomics analysis to be covered here: reference genome-based community composition and functional profiling, along with methods for constructing new genomic references by using de novo assembly. (iscb.org)
  • Over 375 repetitive extragenic palindromic sequences unique to Pss B728a when compared with Pst DC3000 are widely distributed throughout the chromosome except in 14 genomic islands, which generally had lower GC content than the genome as a whole. (nih.gov)
  • Further, detection of genomic-level adaptations to life in the eastern oyster gut were enabled for the class Mollicutes through a metabolic reconstruction of a metagenome-assembled genome. (uri.edu)
  • Overall, these studies advanced our understanding of community and genome-level dynamics of bacteria in temperate coastal ecosystems. (uri.edu)
  • Analysis of free-living, particle-associated, and host-associated bacterial lifestyles in the coastal waters of Rhode Island revealed differences in the taxonomic composition of these communities, identified environmental and host factors that may shape them, and revealed potential genome-level adaptations that contribute to the ability to thrive in a particular lifestyle. (uri.edu)
  • In this context, we have analyzed the genome and proteome composition of N. equitans and compared the same with those of other mesophiles, hyperthermophiles and obligatory host-associated organisms. (biomedcentral.com)
  • The present study reveals that the genome and proteome composition of N. equitans are marked with the signatures of dual adaptation - one to high temperature and the other to obligatory parasitism. (biomedcentral.com)
  • They conducted 16S rRNA and whole genome sequencing to determine diversity, composition and functional potential of the buccal and fecal microbiomes. (mdanderson.org)
  • The degree of organization has been shown to increase with genome size, overall GC composition and the presence of nucleoid-binding proteins [ 1 ]. (biomedcentral.com)
  • Corrigendum: Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea. (mbl.edu)
  • Microbial NGS methods can range from ribosomal RNA analysis (16S rRNA sequencing), to parallel genomic sequencing or shotgun metagenomic sequencing, to whole genome sequencing, to metatranscriptomics. (ddw-online.com)
  • This requires the identification and categorisation of massive sets of genomic sequences corresponding to a huge diversity of bacteria and other microorganisms - a challenge quite distinct from studying the human genome (e.g., identifying single nucleotide polymorphisms or chromosomal rearrangements). (ddw-online.com)
  • ST64 strain that caused necrotizing enterocolitis in a neonate in China and further examine its origin and phylogenetic relationship with ST64 strains based on CRISPR diversity and whole-genome single-nucleotide polymorphism (wgSNP). (cdc.gov)
  • Centre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton, England, United Kingdom of Great Britain and Northern Ireland. (who.int)
  • are applicable to biobanks associated with genome, and the development of genomics population-based studies coordinated by databases and new bioinformatics tools. (who.int)
  • Population-based surveys of the bacteria inhabiting the vagina have shown that several kinds of vaginal microbiota exist, that differs in bacterial composition and abundance. (bmj.com)
  • The impact of both composition and dynamic of the vaginal microbiota on the susceptibility to diseases is still poorly understood. (bmj.com)
  • As central microbiota functions are determined by bacterial community networks, it is important to gain insight into the principles that govern bacteria-bacteria interactions. (nature.com)
  • Based on previous observations that the gut microbiota can improve immune responses, fecal microbiota transplantation has been explored to enhance treatment efficacy by reprogramming the tumor microenvironment in colorectal cancer. (news-medical.net)
  • MetaCherchant: analyzing genomic context of antibiotic resistance genes in gut microbiota. (cdc.gov)
  • The analysis determined the composition, function, and genomic profiles of gut microbiota in participants who developed precancerous colorectal lesions before fecal sampling from 2000 to 2015, and in those participants who developed lesions after fecal sampling, between 2015 and 2022. (medscape.com)
  • Host-derived metabolites, or the metabolites that we as hosts make, shape the ecological balance between the good (commensal) and bad (pathogenic) bacteria in our microbiota. (ccf.org)
  • For his thesis, Apollo applied genomic approaches to dissect disease-promoting interactions between members of the oral microbiota. (ccf.org)
  • The current main research interests of Orho-Melanders´research group are related to prediction and prevention of cardiometabolic diseases with main focus in genetic and circulating biomarkers, diet, gut microbiota and causal risk factors in population based cohorts. (lu.se)
  • For this purpose, we will integrate clinical phenotype data with multi-omics data of human (genomic, metabolomic, proteomic) and gut origin to clarify connections between dietary patterns/intakes, host genetic factors, circulating metabolites and inflammatory proteins and gut microbiota composition, diversity and functional capacity, and how such connections relate to risk of cardiometabolic disease (CMD). (lu.se)
  • WORKPLAN: In two large population cohorts, the SCAPIS-Malmö (N=5008) and Malmö Offspring Study (N=3700), we investigate how gut microbiota composition, diversity and functional capacity are related to diet and associate with cardiometabolic risk traits and incidence of T2D and CVD. (lu.se)
  • Research increasingly demonstrates that within each discrete microbial environment (e.g., the skin, gut, vaginal flora), unique compositions of microbiota correspond to various healthy and diseased states. (ddw-online.com)
  • Metabolic engineering in this bacterium led to development of strains of T. maritima that surpassed the Thauer limit of hydrogen production. (eol.org)
  • [1] One of the strains, also known as Tma200, produced 5.77 mol H 2 / mol glucose which is the highest yield so far reported in a fermentative bacterium. (eol.org)
  • Metagenomic sequencing provides a comprehensive view of the genetic make up of the bacterial species comprising the vaginal microbiome, and highlights associations between different genomic species of the same genus, or strains of the same species and their contribution to the protective properties of the vaginal microbiome. (bmj.com)
  • Limited genomic sequencing is planned for other poorly characterized syntrophic strains to further dissect and predict their metabolic potential along with associated cell-cell interactions within the anaerobic communities. (ucla.edu)
  • In addition, the taxonomic composition of bacterial communities can shift, resulting in higher abundances of strains specialized for a new condition. (uri.edu)
  • We engineered immotile strains of the bacterium Pseudomonas fluorescens that lack flagella due to deletion of the regulatory gene fleQ. (scentoferos.com)
  • ABSTRACT The study evaluated the antimicrobial resistance of molecularly characterized strains of Staphylococcus aureus and S. saprophyticus isolated from 3 Lebanese dairy-based food products that are sometimes consumed raw: kishk, shanklish and baladi cheese. (who.int)
  • Abstract Starting from mature vegetable compost, four bac- the utilization of these bacteria as cell factories for upgrading terial strains were selected using a lignin-rich medium. (lu.se)
  • The application of modern genomic technologies, ecological principles and in vitro modelling affords a better understanding of the role of vaginal microbiome in health and diseases. (bmj.com)
  • We study the diversity, physiology and activity of phytoplankton, prokaryotes (archaea and bacteria) and viruses in diverse marine environmental settings by a variety of techniques, including modern genomic techniques. (fems-microbiology.org)
  • In the present study, we searched the unreported phage genomic fragments from this lake for genes involved in methane oxidation. (nature.com)
  • Additionally, the strain in which the reaction takes place need to be a lysogen (have phage genomic information integrated into their genomes) so that they can create phage particles when they lyse. (igem.org)
  • A shift in the community composition of soil microorganisms in response to warming and bushfire will likely have a substantial role in determining the temperature sensitivity of C cycling processes. (waterra.com.au)
  • Raman microspectroscopy offers microbiologists a rapid and non-destructive technique to assess the chemical composition of individual live microorganisms in near real time. (microbial-ecology.de)
  • 2020). However, since the rank of Candidatus is preliminary and the nomenclature lacks priority, others and we are convinced that genomic information needs to be accepted as type material for the permanent description of novel microorganisms (Konstantinidis et al. (mpi-bremen.de)
  • Microorganisms capable of catabolizing lignin-derived ar- carbohydrate and protein components of the organic matter omatics are essentially fungi and bacteria (Bugg et al. (lu.se)
  • T. maritima is one of fermentative bacteria that produces hydrogen to levels that approach the thermodynamic limit (4 mol H 2 / mol glucose). (eol.org)
  • However, similar to other fermentative bacteria, the hydrogen yield in this bacterium does not go beyond 4 mol H 2 / glucose (Thaeur limit) because of its inherent nature to use more energy for its own cell division to grow rapidly than producing H 2 . (eol.org)
  • Because of these reasons fermentative bacteria have not been thought to produce higher amounts of hydrogen at a commercial scale. (eol.org)
  • In this multi-stage process, fermentative bacteria hydrolyze the polymeric substrates present in all anaerobic habitats and then ferment the hydrolysis products to acetate and longer chain fatty acids, alcohols, aromatic compounds, CO 2 , formate, and H 2 . (ucla.edu)
  • The data discovered during the Tübiom-Project will be used to create a reference database that develops a clearer picture of the gut microbiome compositions within healthy people and those with different diseases. (constantcontact.com)
  • This allowed us to associate gut microbiome compositions and functions to detailed histological information about precancerous lesions and CRC, including when lesions were detected relative to fecal sampling [and a reading of the gut microbiome]," Gacesa explained. (medscape.com)
  • Comparative genomics based methods try to identify regions that show signs that they have been horizontally transferred using information from several related species. (wikipedia.org)
  • For example, a genomic region that is present in one species, but is not present in several other related species suggests that the region may have been horizontally transferred. (wikipedia.org)
  • [7] Additionally, this species of bacteria is able to reduce Fe(III) to produce energy using anaerobic respiration. (eol.org)
  • Host species identity and host evolutionary history were both highly predictive of moss microbiome composition, highlighting strong phylogenetic coherence in these microbial communities. (biomedcentral.com)
  • More generally, the relative importance of environment versus host species in mediating moss microbiome composition remains unresolved. (biomedcentral.com)
  • Likewise, although moss microbial communities appear to be strongly influenced by host identity, it is unclear whether the differences in microbial community composition can be predicted from host phylogenetic relationships, the role of host species effects relative to geographic effects, and importantly, whether the composition of the microbial communities found in a given host species is stable across broad environmental gradients. (biomedcentral.com)
  • The two pathovars of this economically important species of plant pathogenic bacteria differ in host range and other interactions with plants, with Pss having a more pronounced epiphytic stage of growth and higher abiotic stress tolerance and Pst DC3000 having a more pronounced apoplastic growth habitat. (nih.gov)
  • We perform novel type of shotgun metagenomic analysis with precision and coverage far beyond the classical reference -based approaches, enabling detection and quantification of all bacterial species to strain level, and phages. (lu.se)
  • Although few organisms are as practical to study as fast-growing Drosophila , research on other species in the past decade or so has produced multiple reports of common phylogenetic patterns in animals and their microbial residents-a phenomenon known as phylosymbiosis-and scientists have documented various correlations between microbiome composition and host phenotypes. (the-scientist.com)
  • The investigators found that in terms of taxonomic, genomic, and transcriptomic composition, there are distinct ecological boundaries separating both surface water from deep water and polar from nonpolar regions. (sciencedaily.com)
  • While differences in the taxonomic composition of these communities were observed, similar relationships with changing environmental parameters were detected. (uri.edu)
  • Only based on accurate taxonomic concepts and methods, can the diversity and composition of complex microbial communities be accurately described and monitored. (mpi-bremen.de)
  • For the genomic information, the researchers ran single nucleotide polymorphisms (SNP) microarray that interrogated 4,327,108 genetic variants selected from the International HapMap and 1,000 Genomes Projects and targeted genetic variation down to 1% minor allele frequency (MAF). (news-medical.net)
  • In the present study, we reconstructed large phage genomes from freshwater lakes known to contain bacteria that oxidize methane. (nature.com)
  • Viruses associated with Antarctic wildlife: From serology based detection to identification of genomes using high throughput sequencing. (cdc.gov)
  • While these observations were made on free-living bacteria, very few data exist on symbiotic bacteria characterized by reduced genomes, shaped by their adaptation to the host metabolic requirements and by their high evolution rate. (biomedcentral.com)
  • Moreover, transcriptomic analyses have demonstrated that, in free-living bacteria, gene transcription levels and chromosomal organization are mutually influenced. (biomedcentral.com)
  • Using an oligonucleotide-based microarray, we normalized the transcriptomic data by genomic DNA signals in order to have access to inter-gene comparison data. (biomedcentral.com)
  • The isolates were affiliated to 23 genera representing 8 different suborders based on nearly full length 16S rRNA gene sequencing. (uni-wuerzburg.de)
  • Overall our results indicate a rather limited comparability between community structures investigated and determined using different primer pairs as well as between metagenome and 16S rRNA gene amplicon based community structure analysis. (frontiersin.org)
  • This is often done by sequencing a region of a conserved gene that varies among microbes in a group, such as the 16S rRNA gene in bacteria. (asm.org)
  • Patients with higher diversity of bacteria in their digestive tract had longer median progression-free survival (PFS), defined at the time point where half of studied patients have their disease progress. (mdanderson.org)
  • Genomic analyses clustered only one couple together per copy number variation (CNVs). (news-medical.net)
  • Dugong: a Docker image, based on Ubuntu Linux, focused on reproducibility and replicability for bioinformatics analyses. (cdc.gov)
  • At the community level, differences were observed between tissue types based on alpha and beta diversity analyses. (uri.edu)
  • Many genomic islands are flanked by repeat structures and carry fragments of other mobile elements such as phages and plasmids. (wikipedia.org)
  • Bacteriophages (phages), viruses that infect and replicate within bacteria, are important in both natural and human microbiomes because they prey on bacterial hosts, mediate horizontal gene transfer, alter host metabolism and redistribute bacterially derived compounds via host cell lysis 1 . (nature.com)
  • The gut bacterial composition can be modified by environmental factors as probiotics and dietary changes, and by gut bacterial viruses, bacteriophages/prophages (phages). (lu.se)
  • OBJECTIVES: We challenge the question of interrelationships between bacteria and phages in human fecal samples and investigate their connection to dietary intakes and the future risk of T2D and CVD. (lu.se)
  • SIGNIFICANCE: Our study will determine interrelationships between gut bacteria and phages and provide prospective evidence for the role of the gut bacteria and their virus in CMD. (lu.se)
  • For example, the genomic make up of certain vaginal bacteria correlates with their ability to maintain a stable and protective vaginal microbiome. (bmj.com)
  • Pyrosequencing of the 16S ribosomal deoxyribonucleic acid (rDNA) amplicon from genomic DNA extracted from the stool samples was used to analyze the gut microbiome. (news-medical.net)
  • Callahan likens each of these gene amplicon sequences to a barcode that corresponds to a type of bacteria, just like barcodes at a store are assigned to specific items. (asm.org)
  • Automated annotation of mobile antibiotic resistance in Gram-negative bacteria: the Multiple Antibiotic Resistance Annotator (MARA) and database. (cdc.gov)
  • Moreover, co-occurrence interactions between fungi and bacteria, mostly contributed by fungal Ascomycota and bacterial Proteobacteria in control, were reverted to co-exclusive interplay in CRC (p=0.00045). (bmj.com)
  • In particular, low-cost culture-independent sequencing has made metagenomic and metatranscriptomic surveys of microbial communities practical, including bacteria, archaea, viruses, and fungi associated with the human body, other hosts, and the environment. (iscb.org)
  • Genomic regions that show abnormal sequence composition (such as nucleotide bias or codon bias) suggests that these regions may have been horizontally transferred. (wikipedia.org)
  • The genomic comparison suggests that several unique genes for Pss B728a such as ectoine synthase, DNA repair, and antibiotic production may contribute to the epiphytic fitness and stress tolerance of this organism. (nih.gov)
  • A new study carried out by the University of Regensburg on how disturbances to gut bacteria may influence depression , suggests that nutrition and diet combined with other strategies could help treat the disorder. (constantcontact.com)
  • It [also] suggests that gut bacteria might enhance currently used noninvasive fecal tests for the detection of colorectal polyps, and even that microbiome-modulating therapies might play a role in prevention of colorectal cancer ," said Gacesa, who won the award for best abstract in the meeting session. (medscape.com)
  • odoriferum was shown to harbor numerous pseudogenes, which suggests low coding capacity and genomic degradation. (mdpi.com)
  • Patients with metastatic melanoma treated with anti-PD1 checkpoint blockade have their disease controlled longer if they have a more diverse population of bacteria in the gut or an abundance of certain types of bacteria, according to the team's analysis of fecal samples to assess patients' gut microbiomes. (mdanderson.org)
  • By doing that, we were sort of able to move their microbiomes towards an Acetobacter -dominated [composition] or a Lactobacillus -dominated [one]. (the-scientist.com)
  • At the base of the marine food web, microbes act both as primary producers and degraders of organic material. (fems-microbiology.org)
  • For example, in recent decades, patents have been granted on a menagerie of laboratory-created life forms, from microbes like the oil-eating bacterium at issue in a 1980 Supreme Court case to mammals like Harvard's OncoMouse, genetically modified to be cancer-prone. (the-american-interest.com)
  • Hendry will use her funds to collect genomic data on microbes secreted by burying beetles. (cornell.edu)
  • The ability of these microbes to delay decomposition and curb the growth of bacteria associated with decay has piqued the interest of researchers, though little is known about the identities of the specific microbes involved or their functions. (cornell.edu)
  • Genomic Sequencing: Who Controls The Information Your Genes Contain? (medicaldaily.com)
  • Temporal probabilistic modeling of bacterial compositions derived from 16S rRNA sequencing. (cdc.gov)
  • Multiplex PCR-Based Next-Generation Sequencing and Global Diversity of Seoul Virus in Humans and Rats. (cdc.gov)
  • In the interview with the GCRI, Prof. Dr. Franke talks about what motivates him as a researcher and discusses the advantages of next generation sequencing technology for genomic projects and the ethical issues associated with this technology. (constantcontact.com)
  • In addition, long-read sequencing of one representative XDR ST235 isolate identified an integron carrying multiple resistance genes (including bla VIM-2), with differences in gene composition and synteny from the P. aeruginosa class 1 integrons described previously. (who.int)
  • Bacteria employ specific sensory biomolecules (DNA, RNA, or proteins) that can perceive temperature fluctuations and translate them into coordinated gene expression outputs. (waterra.com.au)
  • Since the composition and concentration of proteins and other biological components vary from batch to batch in serum, the reproducibility of experiments with cells that were frozen in a serum-containing medium may be compromised. (cls.shop)
  • Among the conspicuous characteristics featuring its hyperthermophilic adaptation are overrepresentation of purine bases in protein coding sequences, higher GC-content in tRNA/rRNA sequences, distinct synonymous codon usage, enhanced usage of aromatic and positively charged residues, and decreased frequencies of polar uncharged residues, as compared to those in mesophilic organisms. (biomedcentral.com)
  • Codon composition shapes maternal mRNA clearance during the maternal-to-zygotic transition in zebrafish, Xenopus, mouse, and Drosophila, and gene expression during homeostasis across human tissues. (scentoferos.com)
  • Codon composition affects both polyadenylation status and translation efficiency. (scentoferos.com)
  • Probes that match gene sequences of bacteria or viruses present in the sample result in capture of the target gene. (cdc.gov)
  • These bacterial taxa have the genomic potential to produce compounds previously shown to inhibit growth of plant pathogens. (usda.gov)
  • 2014). Today, the genomic revolution is enabling very detailed descriptions of new taxa without cultivation, and it is evident that order must be brought to the rather uncontrolled alphanumerical naming of "novel" (Konstantinidis et al. (mpi-bremen.de)
  • The other plasmid used in this scheme is the oriV version of the entry plasmid that was used in the genomic scheme. (igem.org)
  • Bacteria that live in the human digestive tract can influence how cancer responds to immunotherapy, opening a new avenue for research to improve treatment, a team led by researchers at The University of Texas MD Anderson Cancer Center reports in the journal Science . (mdanderson.org)
  • In many cases, these studies have revealed tantalizing clues of microbiome-driven evolution in animals, including humans, and in some cases, pointed to specific adaptations that likely owe their origin, at least in part, to bacteria in the digestive tract. (the-scientist.com)
  • Anaerobic soil disinfestation (ASD) is an organic amendment-based management practice for controlling soil-borne plant pathogens. (usda.gov)
  • Here I'll discuss the potential for skin bacteria to mitigate infection by two key amphibian pathogens, the chytrid fungus Batrachochytrium dendrobatidis (Bd) and the virus ranavirus. (plymouth.ac.uk)
  • Fundamental knowledge of the strength of interaction between skin bacteria and these pathogens can help us predict the likely spread and severity of infection in natural populations based on the prevalence of protective bacteria in the wild. (plymouth.ac.uk)
  • However, antibiotics cannot differentiate between the beneficial bacteria that help keep us healthy and the pathogens that make us sick. (cdc.gov)
  • Changes in composition and diversity of our gut microbiome are generally accepted as a risk factor for becoming carriers of antibiotic resistant pathogens and developing Clostridium difficile infection. (cdc.gov)
  • In particular, Enterococcus faecalis KB1 was identified as an important driver of community composition by affecting the abundance of several other consortium members in vitro. (nature.com)
  • We found significant but minimal differences in community composition between ASD carbon treatments (F4,30 = 2.80, P (usda.gov)
  • We saw a drop in some commensal bacteria, including F aecalibacterium, in both those with recent pathologies and those who developed them in the future. (medscape.com)
  • A key challenge in microbiome research is to predict the functionality of microbial communities based on community membership and (meta)-genomic data. (nature.com)
  • The ideal candidate has experience in the analysis of high throughput genomic data. (fems-microbiology.org)
  • Toward the end of his degree, he also began working in genomic data analysis-a nod to his future scientific pursuits. (asm.org)
  • The vast and diverse set of microbiome genomic data uncovered by NGS requires sophisticated bioinformatic techniques, which come in the form of microbiome community profiling. (ddw-online.com)
  • Finally, we identified putative N 2 -fixing bacteria specific to some moss hosts, including potential N 2 -fixing bacteria outside well-studied cyanobacterial clades. (biomedcentral.com)
  • Currently, others and we have identified a pressing need to do proper taxonomy of abundant and functionally important clades of environmental bacteria and archaea. (mpi-bremen.de)
  • At the same time, bacteria compete for substrates by employing diverse predatory mechanisms, like the production of bacteriocins [ 8 ]. (nature.com)
  • All types of life have representatives in the plankton -- bacteria, archaea, protists, animals and plants, as well as viruses. (sciencedaily.com)
  • Scientists from the University of Colorado at Boulder and the Centers for Disease Control and Prevention (CDC) have developed a microchip-based test that may allow more labs to diagnose influenza infections and learn more about the viruses causing illness. (cdc.gov)
  • Furthermore, as a step towards rapid genomic analysis, a novel method combining ITP-RCA (Isotachophoresis - Rolling Circle Amplification) was studied and optimized for real-time amplification (RCA), focusing and detection of bacterial DNA in a microfluidic channel (Paper IV). (kth.se)
  • After discovering that the most interesting results of his first Ph.D. project were previously published, Callahan embarked on a second theoretical and computational project exploring polyketide synthase pathways in bacteria , and how horizontal gene transfer affects their adaptive evolution. (asm.org)
  • Under strong selection for motility, these bacteria consistently regained flagella within 96 hours via a two-step evolutionary pathway. (scentoferos.com)
  • However, in obligatory intracellular bacteria, many genes involved in DNA recombination and repair along with the biosynthetic and metabolic genes are usually lost [ 3 , 4 ]. (biomedcentral.com)
  • As a result, this study gives fundamental insight into key drivers and mechanistic basis of the OMM 12 interaction network in vitro, which serves as a knowledge base for future mechanistic in vivo studies. (nature.com)
  • Relating in vitro to in vivo exposures with physiologically based tissue dosimetry and tissue response models. (cdc.gov)
  • Although he and his colleagues didn't dig into what the genetic variation meant for the flies' phenotypes, they did show that it mirrored the variation observed in wild Drosophila populations across geographic latitudes in North America-for instance, alleles associated with a Lactobacillus diet in the experiment are more frequent in populations living at higher latitudes, where these bacteria are more abundant. (the-scientist.com)
  • While the team found no substantial differences in response or progression based on buccal samples, analysis of fecal samples of 30 patients who responded to treatment and 13 who did not told a different story. (mdanderson.org)
  • Although happiness may vary between people based on personal experiences, the researchers found that life satisfaction - one of the factors that determines happiness - decreases after the age of nine and increases between the ages of 70 and 96. (medicaldaily.com)
  • CEMET , a microbiome company started by three researchers and a renowned laboratory in Tübingen, is currently working on creating one of the world's largest microbiome reference databases to better understand the influence of gut bacteria in cancer, Alzheimer's disease, and diabetes. (constantcontact.com)
  • Instead, researchers are interested in the hundreds of tiny fruit flies living on the trees and the even tinier bacteria living inside the insects' guts. (the-scientist.com)
  • The results suggest that these locally made dairy-based foods may act as vehicles for the transmission of antimicrobial-resistant Staphylococcus spp. (who.int)
  • This can be determined by base composition analysis, as well as phylogeny estimations. (wikipedia.org)
  • The captured bacteria on the filter paper was detected using Prussian blue (PB) colorimetric analysis. (kth.se)
  • This method has a huge potential to accelerate the time needed for DNA based analysis for infectious diseases. (kth.se)
  • Analysis of urinary metabolite levels in a probability-based sample. (cdc.gov)
  • In contrast to Bacteria, the archaeal domain was often not particularly addressed in the analysis of microbial communities. (frontiersin.org)
  • CEMET is a company based in Tübingen that specializes in microbiome analysis. (constantcontact.com)
  • The shotgun analysis allows for the identification of genes from all organisms present in a sample, not only the bacteria. (constantcontact.com)
  • In temperate coastal ecosystems, there are a variety of potential environmental niches and lifestyles for bacteria to occupy, along with constantly changing environmental conditions. (uri.edu)
  • The second approach (Paper III) involves a selective cell lysis method where lysis buffer composition is optimized to selectively lyse blood cells in 5 min while maintaining bacterial viability. (kth.se)
  • The genomic DNA (gDNA) is isolated by cell lysis followed by the addition of Proteinase K and RNAse A and purification on columns. (cls.shop)
  • You can either a) infect these bacteria with phage lysate which contains assembly phagemids packaged in phage or b) introduce purified phagemid DNA directly into the strain with oriV entry vector by transformation. (igem.org)
  • Staphylococcus aureus is a bacterium that frequently causes serious infections among hospitalised patients. (hrb.ie)
  • Des isolats suspects de Staphylococcus ont d'abord été identifiés par l'analyse biochimique classique, puis les souches confirmées par amplification en chaîne par polymérase (29 isolats de S. aureus et 17 isolats de S. saprophyticus) ont été analysées pour déterminer leur sensibilité aux différents antimicrobiens. (who.int)
  • Some synonymous codons show consistent stabilizing or destabilizing effects, suggesting that amino acid composition influences mRNA stability. (scentoferos.com)
  • BACKGROUND: Despite evidence supporting a role for the gut bacteria in multitude of human diseases including type 2 diabetes (T2D) and cardiovascular disease (CVD), causal- and mechanistic evidence in humans is limited, and prospective studies are lacking. (lu.se)
  • The current standard first- and second-line treatments for metastatic colorectal cancer include therapies targeting epidermal growth factor (EGF) or vascular endothelial growth factor (VEGF) receptors combined with fluorouracil-based chemotherapy. (news-medical.net)
  • These studies are crucial first steps for identifying promising compositions for biodegradable metallic implants," Moridi said. (cornell.edu)
  • At the completion of these exploratory studies, we will have new intellectual property for composition of biodegradable implants. (cornell.edu)
  • Genomic studies on bacteria have clearly shown the existence of chromosomal organization as regards, for example, to gene localization, order and orientation. (biomedcentral.com)
  • Past genomic studies have comprehensively described the organization of the bacterial chromosome, for example in terms of gene localization, order and orientation. (biomedcentral.com)
  • Two isolates belonging to the genera Streptomyces (SBT348) and Micromonospora (SBT687) were prioritized based on their distinct chemistry profiles as well as their anti-trypanosomal activities. (uni-wuerzburg.de)
  • Using E.coli spiked into the diluted blood sample, bacteria separation is demonstrated at an efficiency of 82 to 90% depending on the blood dilution using a single spiral chip (Paper-II). (kth.se)
  • Organic extraction of tissues with QIAzol effectively removes genomic DNA and improves the efficiency of extracted RNA in downstream applications. (qiagen.com)
  • In early sepsis, the concentration of bacteria in the bloodstream is typically low, making diagnosis challenging. (kth.se)
  • [5] Diagnosis is typically by testing for antibodies against the bacteria or finding bacterial DNA in the blood. (mdwiki.org)
  • Because growth of L. pneumophila in the environment is hypothesized to be dependent partly on the composition of local amebic populations ( 9 ), we isolated free-living amebae hosts from the hot tub samples. (cdc.gov)
  • Then, the team added plates of food: control fly populations received standard food, while others got food laced with one of two bacteria commonly found in the insects' guts, Acetobacter and Lactobacillus . (the-scientist.com)
  • Overcoming this limit by improving the conversion of sugar to H 2 could lead to a superior H 2 producing biological system that may supersede fossil fuel-based H 2 production. (eol.org)
  • The Mayo -based rejections generally involved claims to 'measurement of biologically-relevant (sic) molecules in a biological sample' that 'will correlate with a definable aspect of patient care. (patentdocs.org)