Many approaches can be taken for determining the identity of an incorporated terminator, including fluorescence labeling, mass labeling for mass spectrometry, isotope labeling, and tagging the base with a hapten and detecting chromogenically with an anti-hapten antibody-enzyme conjugate (e.g., via an ELISA format). (wikipedia.org)
Tools3
His research utilizes the tools of synthetic chemistry, protein biochemistry, and cancer biology to discover and validate new strategies for the inhibition of anti-cancer targets. (stanford.edu)
The invention relates in general to hydrophilic, biocompatible dendronised polymers, to complexes comprising the dendronised polymers, to methods of preparing the dendronised polymer and to uses of the dendronised polymer as a non-viral transfection agent for the delivery of biomolecules, in particular, genome editing tools, into a cell. (justia.com)
When utilizing traditional tools and methods to monitor and control changes in a lab environment, it can be difficult to get a 24/7 lab-wide view. (perkinelmer.com)
Technology2
Illumina, Inc. utilizes this method in their Infinium technology (http://www.illumina.com/technology/beadarray-technology/infinium-hd-assay.html) to measure DNA methylation levels in the human genome. (wikipedia.org)
As part of the strategic alliance, Genzyme will develop and commercialize mipomersen, a breakthrough, potential blockbuster lipid-lowering treatment for high risk cardiovascular patients that utilizes Isis' antisense technology. (combichem.net)
Antigens1
Conjugate vaccines use carrier proteins to increase the immunogenicity of antigens (e.g., peptides, oligosaccharides, polysaccharides) and other haptens. (genengnews.com)
Conjugate2
Many approaches can be taken for determining the identity of an incorporated terminator, including fluorescence labeling, mass labeling for mass spectrometry, isotope labeling, and tagging the base with a hapten and detecting chromogenically with an anti-hapten antibody-enzyme conjugate (e.g., via an ELISA format). (wikipedia.org)
CRM 197 , which has a single amino acid substitution of glutamic acid for glycine, is a well-characterized carrier protein and is utilized in a number of approved conjugate vaccines for diseases such as meningitis and pneumococcal bacterial infection. (genengnews.com)
Subsequently2
Other solid supports, such as glass slides and nitrocellulose membranes, were subsequently utilized to develop arrays which could accommodate larger panels of antibodies. (wikipedia.org)
Used to support large-scale mapping and sequencing efforts related to the human genome project, FISH accuracy and versatility were subsequently capitalized on in biological and medical research, providing a wealth of diverse applications and FISH-based diagnostic assays. (biosyn.com)
Carrier1
19. Enhancing Antibody Response against Small Molecular Hapten with Tobacco Mosaic Virus as a Polyvalent Carrier. (nih.gov)
Human Genome1
Interest in screening large protein sets only arose as a result of the achievements in genomics by DNA microarrays and the Human Genome Project . (wikipedia.org)
Compound1
Proven methodological methods including, natural make any difference digestion, thickness separation, compound removal and also polymer-bonded detection ended up utilized. (nitazoxanideinhibitor.com)
Target1
Furthermore, to detect the interaction between displayed protein and those other molecules or isolate specific target binders, Creative Biolabs also utilizes the novel biopanning strategies to select high-affinity binders or ligands which are able to recognize the naïve targets. (stratech.co.uk)
Analysis3
The invention also relates to methods of performing genome-wide location analysis, and ChIP-CHIP analysis, using histones and modified histones. (justia.com)
This application claims the benefit of the filing date of U.S. Application No. 60/711,253, filed Aug. 25, 2005, entitled "NOVEL METHODS FOR GENOME-WIDE LOCATION ANALYSIS. (justia.com)
Genome-wide analysis methods have been used to determine how tagged transcriptional regulators encoded in Saccharomyces cerevisae are associated with the genome in living yeast cells and to model the transcriptional regulatory circuitry of these cells. (justia.com)
Cells2
The first demonstration of antigen-specific recall responses by NK cells was in the setting of hapten-induced contact hypersensitivity, where CXCR6 + liver-derived murine NK cells could mediate antigen-specific contact hypersensitivity independently from B and T cells [ 13 , 14 ]. (hindawi.com)
14. Utilizing Viral Nanoparticle/Dendron Hybrid Conjugates in Photodynamic Therapy for Dual Delivery to Macrophages and Cancer Cells. (nih.gov)
Array1
ii) identifying a location on a chromosome to which the DNA-binding protein of interest binds by obtaining results from an array hybridization experiment in which DNA fragment sequences, which have been bound by the protein of interest, are hybridized to a nucleic acid array comprising known sequences, thereby identifying regions of the genome to which the DNA-binding protein binds. (justia.com)
Library1
Recent work has reported the automated generation of a diverse library of multifunctional dihydropyrimidines (DHPMs) utilizing a microwave-mediated solution phase Biginelli three component condensation. (combichem.net)