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  • activity
  • Class IIa bacteriocins from lactic acid bacteria are small, cationic proteins with antilisterial activity. (biomedcentral.com)
  • They exhibit important technological properties, e.g. thermostability and retaining of activity at a wide pH range, which along with the bactericidal action against Gram-positive food spoilage and pathogenic bacteria, make them an important class of biopreservatives. (biomedcentral.com)
  • group
  • The bacteriocins produced by lactic acid bacteria (LAB) are divided into three main groups: the lantibiotics, which are modified bacteriocins (class I), the nonlantibiotics, which are heat-stable and unmodified (class II), and a group of large heat-labile bacteriocins (class III). (biomedcentral.com)
  • Bifidobacteria
  • Bifidobacteria , called probiotics, are a natural part of the bacterial flora in the human body and have a symbiotic bacteria-host relationship with humans. (kenyon.edu)
  • This pathway, called the bifid shunt, uses the key enzyme frutose-6-phosphate phosphoketolase (F6PPK) and is the generally used as a diagnostic test for this Bifidobacteria because it's not found in other gram-positive intestinal bacteria. (kenyon.edu)
  • When breast-fed infants' diets are changed to cows milk and solid food, Bifidobacteria are joined by rising numbers of other bacteria found in the human body such as Bacteroides and Streptococci lactobacilli . (kenyon.edu)
  • in addition, because Bifidobacteria produces lactic acid instead of gas (like E. coli) , infants and people in general with more Bifidobacteria than other bacteria will have less gas and digestive problems. (kenyon.edu)
  • Bifidobacteria as well as other beneficial bacteria can be found in fermented dairy foods, especially yogurt. (kenyon.edu)
  • Bifidobacteria exert a range of beneficial health effects, including the regulation of intestinal microbial homeostasis, the inhibition of pathogens and harmful bacteria that colonize and/or infect the gut mucosa, the modulation of local and systemic immune responses, the repression of procarcinogenic enzymatic activities within the microbiota, the production of vitamins, and the bioconversion of a number of dietary compounds into bioactive molecules. (kenyon.edu)
  • Bifidobacteria are also able to produce small amounts of succinic acid, although this has never been studied in detail ( 35 ). (asm.org)
  • The aim of this study was to obtain detailed information about the production of succinic acid by bifidobacteria. (asm.org)
  • Detection of bifidobacteria by using propionic acid as a selective agent. (springer.com)
  • In addition, Bifidobacteria produce bacteriocins and bacteriocin-like inhibitory compounds which inhibit the growth of other bacteria. (sigmaaldrich.com)
  • Several functions have been attributed to bifidobacteria, encompassing degradation of non-digestible carbohydrates, protection against pathogens, production of vitamin B, antioxidants, and conjugated linoleic acids, and stimulation of the immune system. (frontiersin.org)
  • It has been shown that the butyrogenic effects of ITF and AXOS are the result of cross-feeding interactions between bifidobacteria and butyrate-producing colon bacteria, such as Faecalibacterium prausnitzii (clostridial cluster IV) and Anaerostipes, Eubacterium , and Roseburia species (clostridial cluster XIVa). (frontiersin.org)
  • These kinds of interactions possibly favor the co-existence of bifidobacterial strains with other bifidobacteria and with butyrate-producing colon bacteria in the human colon. (frontiersin.org)
  • metabolic
  • Baek S-H, Kwon EY, Kim YH, Hahn J-S (2016) Metabolic engineering and adaptive evolution for efficient production of D-lactic acid in Saccharomyes cerevisiae . (springer.com)
  • Beopoulos A, Verbeke J, Bordes F, Guicherd M, Bressy M, Marty A, Nicaud JM (2014) Metabolic engineering for ricinoleic acid production in the oleaginous yeast Yarrowia lipolytica . (springer.com)
  • HAY diets also had a higher metabolic H recovery and methane production (+35%) suggesting more efficient inter-species H transfer between bacteria, protozoa and methanogens. (frontiersin.org)
  • His primary interest lay in the physiological use of organic bound phosphate and the turnover of metabolic energy by its utilization (as "energy rich" or "squiggle" phosphate: ~P) in carbohydrate, fatty acid, amino acid, and nucleic acid syntheses as well as degradations. (encyclopedia.com)
  • For the discovery of coenzyme A as cocatalyst of the metabolic transfer of activated acetate-groups he received the Nobel Prize for Physiology or Medicine in 1953, jointly with Hans Adolf Krebs, who was laureated for untangling the energy-yielding tricarboxylic acid (or "Krebs") cycle, which also (re)utilizes CoA-activated acetate, derived from glucose-borne pyruvate. (encyclopedia.com)
  • There is, therefore, industrial interest in the proteins involved in these metabolic pathways and related transport systems of this bacterium. (royalsocietypublishing.org)
  • 18. The microorganism of claim 16, wherein the heterologous polynucleotide comprises a nucleic acid sequence corresponding to a gene from a C. phytofermentans metabolic pathway. (patentsencyclopedia.com)
  • Metabolic modeling and response surface analysis of an Escherichia coli strain engineered for shikimic acid production BMC Systems Biology, 12, 102. (unam.mx)
  • We refined our metabolic reconstruction according to in vitro observed metabolite consumption and secretion and propose improvements to the current genome annotation of F. prausnitzii A2-165. (asm.org)
  • Because several sugars are ordinarily present in the dough (mainly glucose and maltose), and others may be added (sucrose, high fructose corn syrup), the yeast has a variety of metabolic substrates from which to choose. (buffalobrewingstl.com)
  • group of bacteria
  • Genomics has been crucial in revealing the evolutionary development as well as the biology of any taxonomical group of bacteria and thus in understanding the genetic forces that sustain specific adaptations to an ecological niche ( 15 ). (asm.org)
  • strains
  • The small genomes of lactic acid bacteria encode a broad repertoire of transporters for efficient carbon and nitrogen acquisition from the nutritionally rich environments they inhabit and reflect a limited range of biosynthetic capabilities that indicate both prototrophic and auxotrophic strains. (pnas.org)
  • In an effort to improve the efficiency of this process, growing attention has been devoted to engineering new strains capable of simultaneously utilizing multiple sugars. (biomedcentral.com)
  • Hexose transporter-deficient yeast strains are valuable testbeds for the study of sugar transport by native and heterologous transporters. (tudelft.nl)
  • The resultant engineered strains also lend insight into energetic and redox balance and elucidate mechanisms governing organic acid biosynthesis in this important natural SA-producing microbe. (asm.org)
  • amino
  • The AcCoA is interconverted with amino acids and fatty acids. (asmscience.org)
  • He also initiated research on the nonribosomal synthesis of linear and cyclic (antibiotic) peptides by specifically arranged multienzyme complexes with pantetheine at its active center and on the milieu dependence of the chemical phosphate potential of phosphorylated amino acids in phosphoproteins. (encyclopedia.com)
  • and,c) a polypeptide comprising an amino acid sequence having at least 90% sequence identity with an amino acid sequence as set forth in SEQ ID NO: 210, 290, 104, or 198, wherein said polypeptide has biological activity. (patentsencyclopedia.com)
  • 8. The polypeptide of claim 7 further comprising a heterologous amino acid sequence. (patentsencyclopedia.com)
  • microbes
  • Production of Cinnamic and p-Hydroxycinnamic Acids in Engineered Microbes Frontiers in Bioengineering and Biotechnology, 3, 116. (unam.mx)
  • The Human Microbiome Project ( 3 ) catalog currently contains over 700 reference genomes of human gut microbes, most of which are still biochemically uncharacterized. (asm.org)
  • strain
  • In this study, a "dual-channel" process was implemented to engineer strain MW3 for simultaneous utilization of glucose and xylose, using l -lactic acid as a target product. (biomedcentral.com)
  • In the popular Saccharomyces cerevisiae strain EBY.VW4000, deletion of 21 transporters completely abolished hexose transport. (tudelft.nl)
  • The Role of the ydiB Gene, Which Encodes Quinate/Shikimate Dehydrogenase, in the Production of Quinic, Dehydroshikimic and Shikimic Acids in a PTS- Strain of Escherichia coli Journal of Molecular Microbiology and Biotechnology, 27, 11-21. (unam.mx)
  • Lactate
  • Increased gene and transcript abundances for sugar import and utilisation and production of lactate, propionate and butyrate were also observed in LMY animals. (beds.ac.uk)
  • pathogenic
  • They exhibit important technological properties, e.g. thermostability and retaining of activity at a wide pH range, which along with the bactericidal action against Gram-positive food spoilage and pathogenic bacteria, make them an important class of biopreservatives. (biomedcentral.com)
  • proteins
  • Class IIa bacteriocins from lactic acid bacteria are small, cationic proteins with antilisterial activity. (biomedcentral.com)
  • The bacteriocins produced by Gram-negative bacteria are most often large proteins (many are larger that 20 kDa) and their inhibition spectrum is rather narrow, spanning to closely related species. (biomedcentral.com)
  • The leitmotif of his work was the enzymatic utilization of chemical-bond-energy from degradation of foodstuffs (essentially, glucose from glycolysis) for the biosynthetic processes involving phosphates and vitamin-derived coenzymes, leading to condensed biomacromolecules such as proteins, nucleic acids, fats, and their conjugates. (encyclopedia.com)
  • convert
  • This part of the sake manufacturing process, therefore, shares similarity with the beer-brewing process, in which malt is used to convert the starch (in barley) to simple sugars. (buffalobrewingstl.com)
  • Escherichia Coli
  • L-Rha catabolic pathways were previously characterized in various bacteria including Escherichia coli . (frontiersin.org)
  • Isolation and Properties of a Regulatory Mutant in the Hexose Phosphate Transport System of Escherichia Coli FEBS Letters. (jove.com)
  • Production of cinnamic and p -hydroxycinnamic acid from sugar mixtures with engineered Escherichia coli Microbial Cell Factories, 14, 6. (unam.mx)
  • pathways
  • Additionally, removal of competitive carbon pathways leads to higher-purity SA but also triggers the generation of by-products not previously described from this organism (e.g., lactic acid). (asm.org)
  • bacterial
  • it is thought that Bifidobacterium's ability to compete with other gastrointestinal bacteria and occupy a large percentage in the bacterial flora of the gastrointestinal region might be partly due to the large variety of molecules that it is able to use for energy (Schell et al . (kenyon.edu)
  • microbiota
  • 2017. Gender differences in bile acids and microbiota in relationship with gender dissimilarity in steatosis induced by diet and FXR inactivation. (ucdavis.edu)
  • bioproducts
  • Four-carbon dicarboxylic acids have long been identified as particularly interesting precursors for bioproducts ( 1 ). (asm.org)
  • succinic acid
  • Succinic acid production was found to be associated with growth and stopped when the energy source was depleted. (asm.org)
  • Lauer and Kandler ( 19 ) have shown that small amounts of succinic acid are probably produced through a CO 2 fixation reaction. (asm.org)
  • Succinic acid (SA), in particular, exhibits properties analogous to petrochemically derived maleic anhydride, a primary precursor to 1,4-butanediol (BDO), unsaturated polyester resins, lubricating oil additives, and an array of other products. (asm.org)
  • yield
  • To maximize the ATP yield on sugar in S. cerevisiae, industrial cultivation is typically performed in aerobic, sugar-limited fed-batch reactors which, due to constraints. (tudelft.nl)
  • In this study, we investigate the contribution that rumen bacteria make to methane yield phenotypes in sheep. (beds.ac.uk)
  • The best H 2 yields were obtained for starch fermentations, and the highest yield of 2.91 mol H 2 / mol hexose was reported for C. butyricum . (biomedcentral.com)
  • gram-positive
  • Gram-positive bacteria most often produce peptide bacteriocins smaller than 6 kDa. (biomedcentral.com)
  • Traditionally LAB have been considered to include low G+C content Gram-positive bacteria included in the phylum Firmicutes that are used as starters for industrial food fermentations, notably those based on raw materials derived from milk, meat and plants. (biomedcentral.com)
  • The carbohydrate transport systems operative in gram-positive and gram-negative bacteria are very similar and most likely developed early in evolution. (asmscience.org)
  • butyrate
  • 2017. Hepatic inflammation caused by dysregulated bile acid synthesis is reversible by butyrate supplementation. (ucdavis.edu)
  • enzymes
  • A novel bifunctional enzyme, L-rhamnulose-phosphate aldolase (RhaE) fused to L-lactaldehyde dehydrogenase (RhaW), which is not homologous to previously characterized L-Rha catabolic enzymes, was identified in diverse bacteria including Chloroflexi, Bacilli, and Alphaproteobacteria. (frontiersin.org)
  • Genetic
  • This reconstruction suggests that its evolution was substantially influenced by genetic adaptations to obtain access to glycans, thereby representing a common and potent evolutionary force in shaping bifidobacterial genomes. (asm.org)
  • biosynthetic
  • The LAB have small genomes encoding a range of biosynthetic capabilities that reflect both prototrophic and auxotrophic characters. (pnas.org)