• In a recent filing with the Securities and Exchange Commission (SEC), genetics company Illumina revealed that it is partnering with the UK government to sequence 100,000 genomes by 2017. (extremetech.com)
  • This webinar will outline a project that performs large-scale and integrative single-cell genome and transcriptome profiling of pediatric acute lymphoblastic leukemia (ALL) cases at diagnosis, during drug treatment, and in case of relapse. (genomeweb.com)
  • When a Listeria isolate from food or the environment is sequenced, GenomeTrakr checks the PulseNet database to identify possible links to Listeria DNA fingerprints from patients. (cdc.gov)
  • For over a decade, researchers have been working on nanopore sequencing, which could eliminate these problems by directly reading off the sequence of long, unprocessed strands of DNA. (technologyreview.com)
  • Researchers also hope the cat genome may help in the fight against several human diseases, which is one reason why the National Human Genome Research Institute authorized the cat genome sequencing project in 2005. (avma.org)
  • Acute Myelogenous Leukemia (AML) has a 5 year survival rate of approximately 20% and kills about 8,000 people/year in the U.S. Until recently, only two mutations had been identified as contributing factors, but researchers at the Washington University School of Medicine in St. Louis have used high-throughput-sequencing to produce the first complete genome of a cancer. (medgadget.com)
  • Researchers have produced the first whole-genome sequence of the Neanderthal genome. (nih.gov)
  • The tool of gene sequencing at SNP level is also used to pinpoint functional variants from association studies and improve the knowledge available to researchers interested in evolutionary biology, and hence may lay the foundation for predicting disease susceptibility and drug response. (wikipedia.org)
  • Many regions of the Neanderthal genome, they found, are more like those of the chimpanzee than present-day humans. (nih.gov)
  • For instance, someone could legally pick up your discarded coffee cup and send a minuscule sample of your saliva out for sequencing to determine if you show a predisposition to neurodegenerative disease. (reuters.com)
  • The genome of the kiwi is an important resource for future comparative analyses with other extinct and living flightless birds", says computational biologist Janet Kelso of the Max Planck Institute for Evolutionary Anthropology. (innovations-report.com)
  • The results of the genome-sequence analyses are published this week in the journal Proceedings of the National Academy of Sciences (PNAS) . (nsf.gov)
  • Until sequencing is ready for prime-time, the focus of pediatric sequencing should be exclusively on identifying diseases or conditions that can impact their present-day medical care," Ross said. (medscape.com)
  • The "next generation" sequencing technologies offered by companies including Illumina and Pacific Biosciences have come a very long way, says Jeffery Schloss, program director for technology development at the National Human Genome Research Institute, but "they leave a fair amount to be desired. (technologyreview.com)
  • Jay Flatley, CEO of sequencing giant Illumina, announced at the Consumer Genetics Conference today that the company had reduced the price of its retail whole-genome sequencing service. (scienceblogs.com)
  • At $19,500 this still isn't in the realm of an impulse buy for most of us, but it's a long way down from the $48,000 that Illumina offered at the launch of its service, and more than an order of magnitude below the $350,000 price paid for the first ever retail genome. (scienceblogs.com)
  • The initial genome sequence, announced on 5 February at the Advances in Genome Biology and Technology meeting on Marco Island, Florida, is from a blood sample collected in 1980 from a 63-year-old man from Utah . (newscientist.com)
  • Because important scientific advances are aided by the widest possible dissemination and exchange of information, Monsanto encourages users of this rice genome sequence database to publish their research. (bio.net)
  • The Boston University lab of Amit Meller, whose technology NobleGen has licensed, received $4.2 million in funding from the National Human Genome Research Institute last September. (technologyreview.com)
  • These methods can be used to quantify gene expression, miRNA expression, and identify alternative splicing events in addition to sequence data. (wikipedia.org)
  • NEW YORK (GenomeWeb) - An international team has sequenced and begun an analysis of the genome of the carrot, Daucus carota . (genomeweb.com)
  • Still, Knome president Jorge Conde warns that the price to its customers will remain higher than the basic cost of sequencing a genome, as much of the value comes from the expert analysis needed to interpret the sequence. (newscientist.com)
  • The DNA of a 4-year-old female Abyssinian cat named Cinnamon has been sequenced, according to a report by Joan U. Pontius, PhD, et al, in the November 2007 issue of Genome Research, which details the first assembly, annotation, and comparative analysis of the domestic cat genome. (avma.org)
  • The genome sequence analysis is expected to lead to health benefits for domestic cats. (avma.org)
  • The analysis provides the first genome-wide look at the similarities and differences of the closest evolutionary relative to humans. (nih.gov)
  • The analysis suggests that up to 2% of the DNA in the genome of present-day people outside of Africa originated in Neanderthals or their ancestors. (nih.gov)
  • A Massachusetts startup called Noblegen is developing a simplified version of nanopore genome-sequencing technology-a technique that promises high speed and low costs but that usually requires complex instruments to carry out. (technologyreview.com)
  • The company won't divulge details of its current prototypes, but says the technology could be scaled up to arrays of 400 by 400 nanopores that sequence over 500 gigabases an hour-or about one genome, covered 30 times, in 15 minutes. (technologyreview.com)
  • Whole genome sequencing (WGS) is a cutting-edge technology that FDA has put to a novel and health-promoting use. (fda.gov)
  • There is scope for improvement, however, as meeting attendees have noted that the technology has problems dealing with repetitive DNA sequences . (newscientist.com)
  • But as prices continue to come down, the technology could also be attractive to companies that are already offering more limited genome scans to members of the public. (newscientist.com)
  • Sean George, chief operating officer of Navigenics in Redwood Shores, California, expects his company to start offering genome sequencing to its customers by early next year - although no decision has yet been taken about which technology they will use. (newscientist.com)
  • As the use of whole genome sequencing expands, CDC's national surveillance systems and laboratory infrastructure must keep pace with the changing technology. (cdc.gov)
  • Human Genome Project is 10 years old, what's next? (extremetech.com)
  • Whole genome sequencing of Listeria began as a one-year project in fall 2013 as a collaboration between the Centers for Disease Control and Prevention, U.S. Food and Drug Administration, U.S. Department of Agriculture, National Center for Biotechnology Information, and state and local health departments. (cdc.gov)
  • One of them, the BabySeq Project, explored the medical, behavioral and economic impacts of sequencing. (medscape.com)
  • After hundreds of thousands of years of prodding both intellectually and physically, after the rise of both human dualism and human dissection, it took little more than a century to build from the discovery of DNA to the total sequence of the human blueprint. (extremetech.com)
  • A DNA sequence is a list of these letters, in a certain order, and the 'letters' are called nucleotides or bases. (warwick.ac.uk)
  • C. crescentus is, to our knowledge, the first free-living α-class proteobacterium to be sequenced and will serve as a foundation for exploring the biology of this group of bacteria, which includes the obligate endosymbiont and human pathogen Rickettsia prowazekii , the plant pathogen Agrobacterium tumefaciens , and the bovine and human pathogen Brucella abortus . (pnas.org)
  • To justify screening all infants in mandatory programs, we need to ensure that the benefits greatly outweigh the harms, and we cannot say this is the case for many of the variants we will identify by sequencing," she told Reuters Health by email. (medscape.com)
  • In doing so, they found that Cinnamon's sequences spanned about 65 percent of the gene-containing regions of the feline genome. (avma.org)
  • By looking at the places where the sequence of bases in one fragment seems to overlap the sequence of bases in another fragment, it is possible to overlap the fragments one by one, and eventually, to work out the whole sequence of the genome. (warwick.ac.uk)
  • Determining the order of bases is called sequencing. (cdc.gov)
  • The subunits are chemically strung together in a long sequence, in the region of 10s or 100s of millions of individual letters per chromosome. (warwick.ac.uk)
  • When James Watson - co-discoverer of the DNA double-helix - became the first individual to have his genome sequenced , in 2007, the cost was around $1 million. (newscientist.com)
  • The CGAP published the largest publicly available collection of cancer expressed sequence tags in 2003. (wikipedia.org)
  • In addition to the publication of the three genomes, this week s issue of Science also includes a paper by NIAID grantee Rick Tarleton, Ph.D., of the University of Georgia, Athens, detailing T. cruzi s proteome--the set of expressed proteins encoded by its genome. (innovations-report.com)
  • It is a biochemical laboratory method for the characterization and identification of the DNA or RNA sequences of cancer cell(s). (wikipedia.org)